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    • 5. 发明公开
    • Inulin products with improved nutritional properties
    • 菊苣生产者动物点心(Nahrungseigenschaften)
    • EP1125507A1
    • 2001-08-22
    • EP00103056.8
    • 2000-02-15
    • Tiense Suikerraffinaderij N.V. (Raffinerie Tirlemontoise S.A.)
    • Frippiat, AnneVan Loo, JanSmits, Georges
    • A23L1/0528
    • A61K31/733A23L29/244
    • The invention relates to novel inulin products and compositions thereof, to their manufacture and to their use for modulating the bacterial flora and the fermentation pattern of inulin in the large intestine of humans and mammals, to their use for providing improved inulin-associated nutritional effects/benefits, and to their use for the manufacture of a pharmaceutical composition for providing said effects/benefits in humans and mammals.
      The novel inulin products consist of a mixture of an easily fermentable inulin (EFI) component (preferably an oligofructose, an agave inulin, or a mixture thereof) and a hardly fermentable inulin (HFI) component (preferably a long-chain inulin with a ( DP ¯ ) ≥ 20, typically chicory inulin with a ( DP ¯ ) ≥ 23), in a weight ratio ranging from 10/90 to 70/30.
      The nutritional effects include improved mineral absorption, particularly calcium and magnesium, bone mineral density increase, reduction of bone mineral density loss, improvement of bone structure, modulation of lipid metabolism, stimulation of the immune system, and anti-cancer effects. The novel inulin products are particularly suitable for the manufacture of a composition or a medicament for preventing, for postponing and for treating osteoporosis in humans, particularly postmenopausal women.
    • 本发明涉及新颖的菊粉产品及其组合物,其制备及其用于调节人类和哺乳动物大肠中菊糖的细菌菌群和发酵模式的用途,用于提供改善的菊粉相关营养效应/ 益处以及用于制造用于在人类和哺乳动物中提供所述效果/益处的药物组合物的用途。 新颖的菊粉产品由容易发酵的菊粉(EFI)组分(优选低聚果糖,龙舌兰菊糖或其混合物)和几乎可发酵的菊粉(HFI)组分(优选长链菊粉与( DP)≥20,通常为(DP)≥23的菊苣菊糖),重量比为10/90至70/30。 营养作用包括改善矿物质吸收,特别是钙和镁,骨矿物质密度增加,骨矿物质密度损失减少,骨结构改善,脂质代谢调节,免疫系统刺激和抗癌作用。 新颖的菊粉产品特别适用于制造用于预防,延缓和治疗人类,特别是绝经后妇女的骨质疏松症的组合物或药物。