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1. 发明授权

US6017598A Multilayer polymer film for a multichamber medical bag and process for fabrication thereof 失效
标题翻译：用于多室医用袋的多层聚合物膜及其制造方法
公开(公告)号：US6017598A
公开(公告)日：2000-01-25
申请号：US564134
申请日：1996-05-28
申请人： Thomas Kreischer , Klaus Heilmann , Thomas Nicola , Michael Zimmermann
发明人： Thomas Kreischer , Klaus Heilmann , Thomas Nicola , Michael Zimmermann
IPC分类号： A61J1/05 , A61J1/00 , A61J1/10 , A61J1/20 , B29C65/00 , B29C65/02 , B29C65/18 , B29C65/76 , B32B7/02 , B32B7/06 , B32B7/10 , B32B27/08 , B65D30/02 , B65D33/14 , B65D77/30 , B65D81/32 , C08L23/02 , C08L23/08 , C08L23/10 , C08L23/12 , C08L23/14 , C08L53/00 , C08L53/02
CPC分类号： A61J1/10 , A61J1/2093 , B29C65/02 , B29C65/76 , B29C66/3472 , B29C66/53262 , B29C66/71 , B29C66/91411 , B29C66/91445 , B29C66/919 , B29C66/9192 , B32B27/08 , B32B7/02 , B32B7/06 , B65D81/3266 , C08L23/02 , C08L23/0815 , C08L23/10 , C08L23/142 , A61M2207/00 , B29C65/18 , B29C65/8207 , B29C65/8215 , B29C66/1122 , B29C66/43 , B29C66/4312 , B29C66/91212 , B29C66/91231 , B29L2009/00 , B29L2031/7148 , C08L2203/02 , C08L23/12 , C08L53/00 , C08L53/02 , Y10S206/828
摘要： The invention concerns a multilayer polymer film and a multichamber bag, whose bag chambers are formed by seams in the outer border zone and by at least one seam in the chamber separation zone, whereby the seams are formed from the polymer materials facing the chambers. The polymer materials facing the chambers are inseparably sealed together in the outer border zone and sealed together in the chamber separation zone such that the seam is separable with a force which lies in the range from 5 to 20 N. The different strength of the bond from the sealing process is obtained by varying sealing temperatures.
摘要翻译： PCT No.PCT / EP95 / 01152 Sec。 371日期：1996年5月28日 102（e）日期1996年5月28日PCT提交1995年3月28日PCT公布。 WO95 / 26177 PCT出版物日期1995年10月5日本发明涉及多层聚合物膜和多室袋，其袋室由外界区域中的接缝和腔室分离区中的至少一个接缝形成，由此由聚合物材料形成接缝面对房间。面向腔室的聚合物材料在外边界区域不可分离地密封在一起并密封在腔室分离区域中，使得接缝可以与5至20N的范围内的力分离。通过改变密封温度来获得密封过程。

2. 发明授权

US5783269A Non-PVC multilayer film for medical bags 失效
标题翻译：医用袋非PVC多层膜
公开(公告)号：US5783269A
公开(公告)日：1998-07-21
申请号：US638249
申请日：1996-04-26
申请人： Klaus Heilmann , Thomas Nicola , Thomas Kreischer
发明人： Klaus Heilmann , Thomas Nicola , Thomas Kreischer
IPC分类号： B65D30/02 , A61J1/10 , B29C47/06 , B32B7/02 , B32B27/00 , B32B27/32 , B65D65/40 , B32B1/08
CPC分类号： B32B27/32 , Y10T428/1334 , Y10T428/1352 , Y10T428/1359 , Y10T428/2826 , Y10T428/31909 , Y10T428/31913 , Y10T428/31917 , Y10T428/31924 , Y10T428/31931
摘要： Non-PVC multi-layer film (1) containing an outer layer (2), a supporting layer (4) together with at least one interposed central layer (3), characterized in that the outer (2) and supporting (4) layers contain polymers having Vicat softening temperatures of above approximately 121.degree. C. and that at least one central layer (3) contains polymers having softening temperatures of below approximately 70.degree. C. The non-PVC multi-layer film (1) is particularly suitable for the production of medical bags, in particular multi-chamber bags, as the materials of the individual layers (2-4) are selected in such a manner that the film is transparent and flexible, but in particular also heat-sterilizable, fusible and heat sealable. The film is moreover completely recyclable.
摘要翻译：包含外层（2），支撑层（4）以及至少一个插入的中间层（3）的非PVC多层膜（1），其特征在于，外层（2）和支撑层（4）层含有维卡软化温度高于约121℃的聚合物，并且至少一个中心层（3）含有软化温度低于约70℃的聚合物。非PVC多层膜（1）特别适用于作为单层（2-4）的材料，以这样的方式选择医用袋，特别是多室袋的生产，使得膜是透明和柔性的，但是特别地也是热可灭菌，易熔和热可密封此外，电影完全可回收。

3. 发明授权

US5928744A PVC-free multilayer tube for medical purposes, process for the production thereof and use 失效
标题翻译：用于医疗目的的无PVC多层管，其生产和使用的方法
公开(公告)号：US5928744A
公开(公告)日：1999-07-27
申请号：US689862
申请日：1996-08-15
申请人： Klaus Heilmann , Thomas Nicola
发明人： Klaus Heilmann , Thomas Nicola
IPC分类号： A61M5/14 , A61J1/10 , A61L29/14 , B29C47/06 , B29L9/00 , B29L23/00 , B32B1/08 , B32B7/02 , B32B27/32 , F16L11/04
CPC分类号： A61M39/08 , A61L29/14 , B29C47/0023 , B29C47/003 , B29C47/065 , B32B1/08 , F16L11/04 , B29L2031/753 , Y10T428/1379 , Y10T428/1383 , Y10T428/1393 , Y10T428/31551 , Y10T428/31797 , Y10T428/3192 , Y10T428/31928
摘要： According to the invention, strong adhesion of the layers to each other and simple formation of a strong and leakproof connection with bags or connectors made from polypropylene or polycarbonate during steam sterilisation is achieved by the first plastic material containing at least one polymer which is dimensionally stable at temperatures of .gtoreq.121.degree. C., while the second plastic material contains at least one polymer which is no longer dimensionally stable at temperatures of .gtoreq.121.degree. C. A layer C) (2) is optionally present, the plastic material of which contains at least one polymer which is dimensionally stable at temperatures of .gtoreq.121.degree. C. The invention can be used for medical purposes, in particular as a fluid line in dialysis, infusion or artificial feeding, primarily in connection with connectors or medical bags.
摘要翻译：根据本发明，通过在蒸汽灭菌过程中，由聚丙烯或聚碳酸酯制成的袋或连接件在彼此之间的牢固的粘附和简单的形成强的和防漏的连接是通过第一塑料材料实现的，该塑料材料含有至少一种尺寸稳定的聚合物在> 121℃的温度下，而第二塑料材料含有至少一种在> 121℃的温度下不再尺寸稳定的聚合物。任选地存在C）（2）层，塑料其材料含有至少一种在> 121℃的温度下尺寸稳定的聚合物。本发明可用于医疗目的，特别是用于透析，输液或人造进料中的流体管线，主要与连接器或医疗袋。

4. 发明授权

US6004311A Connecting arrangement and process for connecting two separate parts of a medical system 失效
标题翻译：用于连接医疗系统的两个单独部件的连接布置和过程
公开(公告)号：US6004311A
公开(公告)日：1999-12-21
申请号：US712099
申请日：1996-09-11
申请人： Klaus Heilmann , Thomas Nicola
发明人： Klaus Heilmann , Thomas Nicola
IPC分类号： A61J1/10 , A61J1/05 , A61M39/02 , C08J5/12 , A61M25/00 , D02G3/00
CPC分类号： C08J5/121 , A61J1/10 , A61J1/1475 , Y10S604/905 , Y10T428/2933 , Y10T428/2935 , Y10T428/2975 , Y10T428/2998
摘要： A connecting arrangement for a medical system, having a first part including a plastic material that is dimensionally stable at a heat-treatment temperature and a second part including a plastic material that is not dimensionally stable at the heat-treatment temperature and thus tends to flow under a compressive force; in which the plastic materials do not contain any PVC or EVA. The connection is made by bringing the surfaces on the first and second parts together with subsequent heat-treatment under a compressive force, wherein the second plastic material tends to flow under the simultaneous effects of temperature and compressive force.
摘要翻译：一种用于医疗系统的连接装置，其具有包括在热处理温度下尺寸稳定的塑料材料的第一部分和包括在热处理温度下尺寸不稳定并因此倾向于流动的塑料材料的第二部件在压力下其中塑料材料不含任何PVC或EVA。通过将第一和第二部件上的表面与压缩力进行随后的热处理一起进行连接，其中第二塑料材料在同时受到温度和压缩力的作用下倾向于流动。

5. 发明授权

US5713850A Apparatus for controlling a fluid flow 失效
标题翻译：用于控制流体流动的装置
公开(公告)号：US5713850A
公开(公告)日：1998-02-03
申请号：US567561
申请日：1995-12-05
申请人： Klaus Heilmann , Josef Herrmann , Claus Jessen , Helmut Schmidt , Christian Schwegmann , Michael Zimmermann
发明人： Klaus Heilmann , Josef Herrmann , Claus Jessen , Helmut Schmidt , Christian Schwegmann , Michael Zimmermann
IPC分类号： A61M1/28 , A61M39/18 , A61M39/22 , F16L33/18 , A61M1/00
CPC分类号： A61M1/285 , A61M39/18 , A61M39/223 , A61M2039/1088 , Y10T137/86863
摘要： Apparatus for controlling a fluid flow includes a housing having a first fitting for connection of a tube and at least one further fitting for detachable securement of a coupling piece of a peritoneal catheter. Accommodated in the housing is a rotary valve which is indexable in predetermined positions to selectively establish a fluid communication between the fittings. Associated with one of the fittings is at least one closure member which is acted upon by the rotary valve for displacement in a radial direction to open and close a passage to the peritoneal catheter.
摘要翻译：用于控制流体流动的装置包括壳体，该壳体具有用于连接管的第一配件和至少一个用于可分离地固定腹膜导管联接件的配件。容纳在壳体中的是旋转阀，其可在预定位置可转位以选择性地在配件之间建立流体连通。与其中一个配件相关联的是至少一个由旋转阀作用的关闭构件，用于沿径向移动以打开和关闭通向腹膜导管的通道。

6. 发明申请

US20060096907A1 Filter device 审中-公开
公开(公告)号：US20060096907A1
公开(公告)日：2006-05-11
申请号：US11314655
申请日：2005-12-20
申请人： Uwe Hahmann , Klaus Heilmann , Michael Schonhofen , Gerhard Wiesen
发明人： Uwe Hahmann , Klaus Heilmann , Michael Schonhofen , Gerhard Wiesen
IPC分类号： B01D63/02
CPC分类号： B01D63/022 , B01D63/02 , B01D63/023 , B01D65/00 , B01D2313/20
摘要： A filter device having two flow paths. The first flow path having at least one cap and fluid port. The second flow path surrounding the first fluid flow path and having at least one cap that overlaps the cap of the first fluid flow path. The second flow path also having at least one fluid port. The filter device providing a simple arrangement that is easily disinfected or sterilized.

7. 发明授权

US06776909B2 Filter device 有权
标题翻译：过滤装置
公开(公告)号：US06776909B2
公开(公告)日：2004-08-17
申请号：US10167520
申请日：2002-06-12
申请人： Uwe Hahmann , Klaus Heilmann , Michael Schönhofen , Gerhard Wiesen
发明人： Uwe Hahmann , Klaus Heilmann , Michael Schönhofen , Gerhard Wiesen
IPC分类号： B01D6302
CPC分类号： B01D63/022 , B01D63/02 , B01D63/023 , B01D65/00 , B01D2313/20
摘要： A filter device has two flow paths. The first flow path having at least one cap and fluid port. The second flow path surrounding the first fluid flow path and having at least one cap that overlaps the cap of the first fluid flow path. The second flow path also having at least one fluid port. The filter device providing a simple arrangement that is easily disinfected or sterilized.
摘要翻译：过滤装置具有两个流动路径。第一流路具有至少一个盖和流体端口。第二流路围绕第一流体流动路径并且具有与第一流体流动路径的盖重叠的至少一个盖。第二流路还具有至少一个流体端口。过滤装置提供易于消毒或灭菌的简单布置。

8. 发明授权

US06419825B1 Closure element 有权
标题翻译：封闭元素
公开(公告)号：US06419825B1
公开(公告)日：2002-07-16
申请号：US09441182
申请日：1999-11-15
申请人： Uwe Hahmann , Christian Sauerwald , Klaus Heilmann , Gerhard Breith , Steffen Fritzsche , Igor Raiko
发明人： Uwe Hahmann , Christian Sauerwald , Klaus Heilmann , Gerhard Breith , Steffen Fritzsche , Igor Raiko
IPC分类号： A61M3920
CPC分类号： A61M39/20 , A61M1/169 , B01D61/30 , B01D65/00 , B01D65/022
摘要： A closure element for sterile closure of connections, in particular connections of filter modules for dialysis, hemofiltration or ultrafiltration is described. A closure element with a simple design that provides a reliable seal is formed by having the closure element include a wall with an automatically closing slit-shaped indentation which when closed creates a germ-proof seal. The sealing element is used for sterile closure of connections of medical items, as well as for the medical items themselves.
摘要翻译：描述了用于无菌封闭连接的闭合元件，特别是用于透析，血液滤过或超滤的过滤器模块的连接。具有提供可靠密封的简单设计的封闭元件通过具有封闭元件包括具有自动闭合的狭缝形凹陷的壁而形成，其在闭合时形成防菌密封。密封元件用于无菌封闭医疗用品的连接以及医疗用品本身。

9. 发明授权

US6053967A Air separator 失效
标题翻译：空气分离器
公开(公告)号：US6053967A
公开(公告)日：2000-04-25
申请号：US295430
申请日：1994-08-25
申请人： Klaus Heilmann , Bernd Knierbein
发明人： Klaus Heilmann , Bernd Knierbein
IPC分类号： A61M1/36 , B01D19/00
CPC分类号： A61M1/3627 , B01D19/0057 , A61M2206/16
摘要： An air separator for liquid containing gas bubbles having an essentially cylinder-shaped chamber through which liquid, such as blood, flows essentially in helical flow paths, with the result that air bubbles are driven in a radial direction relative to the longitudinal axis of the chamber because of pressure differences produced by centrifugal forces. The inlet and outlet of the chamber of the air separator are coaxial relative to each other in the longitudinal axis of the chamber. The air separator also includes a flow-deflection component or influx distributor, which includes a rotation-symmetrical base body element whose outer surface faces inflowing liquid as a first deflection surface, which is geometrically defined by rotation of a curve section about the longitudinal axis of the chamber. The first deflection surface has deflection surface deflector vanes, which are curved in planes perpendicular relative to the longitudinal axis of the chamber, with the result that axially inflowing liquid is deflected so that desired helical flow development is induced.
摘要翻译：一种用于含有气泡的液体的空气分离器，其具有基本上圆柱形的腔室，诸如血液的液体通过其基本上在螺旋形流动路径中流动，结果是气体相对于腔室的纵向轴线在径向方向上被驱动因为由离心力产生的压差。空气分离器的室的入口和出口在腔室的纵向轴线中彼此相同。空气分离器还包括流动偏转部件或流入分配器，其包括旋转对称的基体元件，其外表面面向作为第一偏转表面的流入液体，该第一偏转表面通过围绕纵向轴线的曲线部分的旋转限定房间。第一偏转表面具有偏转表面偏转叶片，其在相对于腔室的纵向轴线垂直的平面中弯曲，结果是轴向流入的液体被偏转，从而引起期望的螺旋流动展开。

10. 发明授权

US4274964A Dialysator 失效
标题翻译：透析器
公开(公告)号：US4274964A
公开(公告)日：1981-06-23
申请号：US65075
申请日：1979-08-09
申请人： Gerd Krick , Peter Konang , Jan-Erik Sigdell , Klaus Heilmann
发明人： Gerd Krick , Peter Konang , Jan-Erik Sigdell , Klaus Heilmann
IPC分类号： A61M1/22 , B01D63/00 , B01D63/14 , B01D31/00
CPC分类号： B01D61/28 , B01D63/06 , B01D63/14 , Y10T156/1015
摘要： A dialyzer is formed by first placing a film strip into a membrane hose and then simultaneously folding the hose and a netting intermediate layer so that the folds of the hose and the folds of the netting extend crosswise relative to each other in a mutually interlocking manner. The facing ends of the hose layers are then sealed with a curable sealing compound and severed. Then the film strips are withdrawn from the hoses in the so formed package. The resulting product is a dialyzer or hemofilter, depending on the type of membrane hose used, in which the facing ends of the membrane hoses are open for the passage of blood therethrough, after the withdrawal of the film, and in which the netting layers are located between adjacent hoses.
摘要翻译：通过首先将膜条放置在膜软管中，然后同时折叠软管和网状中间层，使得软管的折叠和网的折叠以相互互锁的方式相对于彼此横向延伸，形成透析器。然后将软管层的相对端用可固化的密封化合物密封并切断。然后将薄膜条从如此形成的包装中的软管中取出。所得到的产品是透析器或血液滤膜器，取决于所用的膜软管的类型，其中膜软管的面对端打开以使血液通过其中，在膜退出之后，其中网状层是位于相邻软管之间。

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