专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07812054B2 Lipoxin analogs and methods for the treatment of periodontal disease 有权
标题翻译：脂氧素类似物和治疗牙周病的方法
公开(公告)号：US07812054B2
公开(公告)日：2010-10-12
申请号：US12539728
申请日：2009-08-12
申请人： Thomas E. Van Dyke , Nicos A. Petasis , Charles N. Serhan
发明人： Thomas E. Van Dyke , Nicos A. Petasis , Charles N. Serhan
IPC分类号： A01N37/06
CPC分类号： A61K31/202 , A61K31/22 , A61K31/365 , C07B2200/07 , C07C69/732 , C07C69/736 , C07C229/30 , C07C235/28 , C07C259/06 , C07C2601/16 , A61K2300/00
摘要： This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invention also provides for methods of treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease with compositions containing COX-2 inhibitors. Further, the invention provides methods for preventing systemic diseases beyond theoral cavity that are related to periodontal disease using the composition containing lipoxin analogs, COX-2 inhibitors, or both.
摘要翻译：本发明提供了新的脂氧素类似物，含有类似物的组合物，以及使用这些化合物和组合物治疗和预防口腔炎症的方法，包括牙龈炎，牙周炎和其它形式的牙周病。本发明还提供了含有COX-2抑制剂的组合物治疗和预防口腔炎症的方法，包括牙龈炎，牙周炎和其他形式的牙周病。此外，本发明提供了使用含有脂氧素类似物，COX-2抑制剂或两者的组合物来预防与牙周疾病相关的全腔外疾病的方法。

2. 发明申请

US20090311201A1 LIPOXIN ANALOGS AND METHODS FOR THE TREATMENT OF PERIODONTAL DISEASE 有权
标题翻译： LIPOXIN类似物和治疗周围疾病的方法
公开(公告)号：US20090311201A1
公开(公告)日：2009-12-17
申请号：US12539728
申请日：2009-08-12
申请人： Thomas E. Van Dyke , Nicos A. Petasis , Charles N. Serhan
发明人： Thomas E. Van Dyke , Nicos A. Petasis , Charles N. Serhan
IPC分类号： A61K8/365 , C07C59/48 , A61K31/192 , A61P29/00 , A61P31/00 , A61Q11/00
CPC分类号： A61K31/202 , A61K31/22 , A61K31/365 , C07B2200/07 , C07C69/732 , C07C69/736 , C07C229/30 , C07C235/28 , C07C259/06 , C07C2601/16 , A61K2300/00
摘要： This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invention also provides for methods of treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease with compositions containing COX-2 inhibitors. Further, the invention provides methods for preventing systemic diseases beyond theoral cavity that are related to periodontal disease using the composition containing lipoxin analogs, COX-2 inhibitors, or both.
摘要翻译：本发明提供了新的脂氧素类似物，含有类似物的组合物，以及使用这些化合物和组合物治疗和预防口腔炎症的方法，包括牙龈炎，牙周炎和其他形式的牙周病。本发明还提供了含有COX-2抑制剂的组合物治疗和预防口腔炎症的方法，包括牙龈炎，牙周炎和其他形式的牙周病。此外，本发明提供了使用含有脂氧素类似物，COX-2抑制剂或两者的组合物来预防与口腔疾病相关的全腔外疾病的方法。

3. 发明授权

US07700650B2 Lipoxin analogs and method for the treatment of periodontal disease 有权
标题翻译：脂氧素类似物和治疗牙周病的方法
公开(公告)号：US07700650B2
公开(公告)日：2010-04-20
申请号：US10239444
申请日：2001-03-20
申请人： Thomas E. Van Dyke , Nicos A. Petasis , Charles N. Serhan
发明人： Thomas E. Van Dyke , Nicos A. Petasis , Charles N. Serhan
IPC分类号： A01N37/06
CPC分类号： A61K31/202 , A61K31/22 , A61K31/365 , C07B2200/07 , C07C69/732 , C07C69/736 , C07C229/30 , C07C235/28 , C07C259/06 , C07C2601/16 , A61K2300/00
摘要： This invention provides new lipoxin analogs, compositions containing these analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invention also provides for methods of treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease with compositions containing COX-2 inhibitors. Further, the invention provides methods for preventing systemic diseases beyond theoral cavity that are related to periodontal disease using the compositions containing lipoxin analogs, COX-2 inhibitors, or both.
摘要翻译：本发明提供新的脂氧素类似物，含有这些类似物的组合物，以及使用这些化合物和组合物治疗和预防口腔炎症的方法，包括牙龈炎，牙周炎和其它形式的牙周病。本发明还提供了含有COX-2抑制剂的组合物治疗和预防口腔炎症的方法，包括牙龈炎，牙周炎和其他形式的牙周病。此外，本发明提供了使用含有脂氧素类似物，COX-2抑制剂或两者的组合物来预防与口腔疾病相关的全腔外疾病的方法。

4. 发明授权

US08604229B2 Lipoxin analogs and methods for the treatment of periodontal disease 有权
标题翻译：脂氧素类似物和治疗牙周病的方法
公开(公告)号：US08604229B2
公开(公告)日：2013-12-10
申请号：US13346543
申请日：2012-01-09
申请人： Thomas E. Van Dyke , Nicos A. Petasis , Charles N. Serhan
发明人： Thomas E. Van Dyke , Nicos A. Petasis , Charles N. Serhan
IPC分类号： C07C59/00
CPC分类号： A61K31/202 , A61K31/22 , A61K31/365 , C07B2200/07 , C07C69/732 , C07C69/736 , C07C229/30 , C07C235/28 , C07C259/06 , C07C2601/16 , A61K2300/00
摘要： This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invention also provides for methods of treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease with compositions containing COX-2 inhibitors. Further, the invention provides methods for preventing systemic diseases beyond the oral cavity that are related to periodontal disease using the composition containing lipoxin analogs, COX-2 inhibitors, or both.
摘要翻译：本发明提供了新的脂氧素类似物，含有类似物的组合物，以及使用这些化合物和组合物治疗和预防口腔炎症的方法，包括牙龈炎，牙周炎和其它形式的牙周病。本发明还提供了含有COX-2抑制剂的组合物治疗和预防口腔炎症的方法，包括牙龈炎，牙周炎和其他形式的牙周病。此外，本发明提供使用含有脂氧素类似物，COX-2抑制剂或两者的组合物来预防与牙周疾病相关的口腔以外的全身疾病的方法。

5. 发明申请

US20120114566A1 LIPOXIN ANALOGS AND METHODS FOR THE TREATMENT OF PERIODONTAL DISEASE 有权
标题翻译： LIPOXIN类似物和治疗周围疾病的方法
公开(公告)号：US20120114566A1
公开(公告)日：2012-05-10
申请号：US13346543
申请日：2012-01-09
申请人： Thomas E. Van Dyke , Nicos A. Petasis , Charles N. Serhan
发明人： Thomas E. Van Dyke , Nicos A. Petasis , Charles N. Serhan
IPC分类号： A61K9/68 , C07C229/40 , A61P29/00 , C07C59/48 , C07C59/42 , A61P1/04 , A61K31/20 , C07C59/46
CPC分类号： A61K31/202 , A61K31/22 , A61K31/365 , C07B2200/07 , C07C69/732 , C07C69/736 , C07C229/30 , C07C235/28 , C07C259/06 , C07C2601/16 , A61K2300/00
摘要： This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invention also provides for methods of treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease with compositions containing COX-2 inhibitors. Further, the invention provides methods for preventing systemic diseases beyond theoral cavity that are related to periodontal disease using the composition containing lipoxin analogs, COX-2 inhibitors, or both.
摘要翻译：本发明提供了新的脂氧素类似物，含有类似物的组合物，以及使用这些化合物和组合物治疗和预防口腔炎症的方法，包括牙龈炎，牙周炎和其它形式的牙周病。本发明还提供了含有COX-2抑制剂的组合物治疗和预防口腔炎症的方法，包括牙龈炎，牙周炎和其他形式的牙周病。此外，本发明提供了使用含有脂氧素类似物，COX-2抑制剂或两者的组合物来预防与口腔疾病相关的全腔外疾病的方法。

6. 发明授权

US08093417B2 Lipoxin analogs and methods for the treatment of periodontal disease 有权
标题翻译：脂氧素类似物和治疗牙周病的方法
公开(公告)号：US08093417B2
公开(公告)日：2012-01-10
申请号：US12892872
申请日：2010-09-28
申请人： Thomas E. Van Dyke , Nicos A. Petasis , Charles N. Serhan
发明人： Thomas E. Van Dyke , Nicos A. Petasis , Charles N. Serhan
IPC分类号： C07C59/00
CPC分类号： A61K31/202 , A61K31/22 , A61K31/365 , C07B2200/07 , C07C69/732 , C07C69/736 , C07C229/30 , C07C235/28 , C07C259/06 , C07C2601/16 , A61K2300/00
摘要： This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invention also provides for methods of treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease with compositions containing COX-2 inhibitors. Further, the invention provides methods for preventing systemic diseases beyond theoral cavity that are related to periodontal disease using the composition containing lipoxin analogs, COX-2 inhibitors, or both.
摘要翻译：本发明提供了新的脂氧素类似物，含有类似物的组合物，以及使用这些化合物和组合物治疗和预防口腔炎症的方法，包括牙龈炎，牙周炎和其它形式的牙周病。本发明还提供了含有COX-2抑制剂的组合物治疗和预防口腔炎症的方法，包括牙龈炎，牙周炎和其他形式的牙周病。此外，本发明提供了使用含有脂氧素类似物，COX-2抑制剂或两者的组合物来预防与口腔疾病相关的全腔外疾病的方法。

7. 发明申请

US20110064677A1 LIPOXIN ANALOGS AND METHODS FOR THE TREATMENT OF PERIODONTAL DISEASE 有权
标题翻译： LIPOXIN类似物和治疗周围疾病的方法
公开(公告)号：US20110064677A1
公开(公告)日：2011-03-17
申请号：US12892872
申请日：2010-09-28
申请人： Thomas E. Van Dyke , Nicos A. Petasis , Charles N. Serhan
发明人： Thomas E. Van Dyke , Nicos A. Petasis , Charles N. Serhan
IPC分类号： A61K31/201 , C07C59/48 , A61K31/635 , A61K31/341 , A61K31/42 , A61K8/365 , A61K9/68 , A61K9/12 , A61P1/00 , A61P29/00 , A61P43/00 , A61Q11/00
CPC分类号： A61K31/202 , A61K31/22 , A61K31/365 , C07B2200/07 , C07C69/732 , C07C69/736 , C07C229/30 , C07C235/28 , C07C259/06 , C07C2601/16 , A61K2300/00
摘要： This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invention also provides for methods of treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease with compositions containing COX-2 inhibitors. Further, the invention provides methods for preventing systemic diseases beyond theoral cavity that are related to periodontal disease using the composition containing lipoxin analogs, COX-2 inhibitors, or both.
摘要翻译：本发明提供了新的脂氧素类似物，含有类似物的组合物，以及使用这些化合物和组合物治疗和预防口腔炎症的方法，包括牙龈炎，牙周炎和其它形式的牙周病。本发明还提供了含有COX-2抑制剂的组合物治疗和预防口腔炎症的方法，包括牙龈炎，牙周炎和其他形式的牙周病。此外，本发明提供了使用含有脂氧素类似物，COX-2抑制剂或两者的组合物来预防与牙周疾病相关的全腔外疾病的方法。

8. 发明申请

US20110135716A1 DELIVERY OF H2 ANTAGONISTS 审中-公开
标题翻译：交付H2拮抗剂
公开(公告)号：US20110135716A1
公开(公告)日：2011-06-09
申请号：US13027437
申请日：2011-02-15
申请人： Thomas E. Van Dyke , Michael Holick , Alpdogan Kantarci , Hatice Hasturk
发明人： Thomas E. Van Dyke , Michael Holick , Alpdogan Kantarci , Hatice Hasturk
IPC分类号： A61K9/127 , A61K31/4164 , A61K31/426 , A61K31/341 , A61P1/02
CPC分类号： A61K9/0002 , A61K9/0063 , A61K9/127 , A61K9/1277 , A61K31/341 , A61K31/4164 , A61K31/426
摘要： The present invention provides improved systems and methods for the local delivery of H2 antagonists. The inventive methods include topical administration of an effective amount of a H2 antagonist encapsulated in liposomes. In certain embodiments, the H2 antagonist, for example, Cimetidine, is encapsulated into paucilamellar liposomes, such as NOVASOME® microvesicles. Also provided are pharmaceutical compositions comprising liposome-encapsulated H2 antagonists. The methods and compositions of the present invention may be used to treat any disease state or condition where local administration of H2 antagonists is beneficial.
摘要翻译：本发明提供了用于局部递送H 2拮抗剂的改进的系统和方法。本发明的方法包括局部施用包封在脂质体中的有效量的H 2拮抗剂。在某些实施方案中，将H 2拮抗剂（例如西咪替丁）包封在微囊脂质体如微泡中。还提供了包含脂质体包封的H2拮抗剂的药物组合物。本发明的方法和组合物可用于治疗H 2拮抗剂的局部给药有益的任何疾病状态或病症。

9. 发明申请

US20140315807A1 Treatment and Prevention of Bone Loss Using Resolvins 有权
标题翻译：使用溶栓剂治疗和预防骨丢失
公开(公告)号：US20140315807A1
公开(公告)日：2014-10-23
申请号：US14134627
申请日：2013-12-19
申请人： Thomas E. Van Dyke
发明人： Thomas E. Van Dyke
IPC分类号： A61K31/202 , A61K45/06
CPC分类号： A61K31/202 , A61K31/22 , A61K31/557 , A61K31/663 , A61K45/06 , A61K2300/00
摘要： The invention provides new methods for inducing or promoting bone growth and/or for reducing or preventing bone deterioration in a mammal subject. The inventive methods generally comprise administering to the subject an effective amount of a resolving. In particular, the inventive methods may be useful for treating or preventing conditions associated with bone degradation, deterioration or degeneration such as periodontal disease, osteoarthritis, and metastatic bone disease and osteolytic bone disease. Pharmaceutical compositions and kits comprising at least one resolving are also provided that can be used to performed the inventive methods.
摘要翻译：本发明提供用于诱导或促进骨生长和/或用于减少或预防哺乳动物受试者的骨质退化的新方法。本发明的方法通常包括向受试者施用有效量的分辨。特别地，本发明的方法可用于治疗或预防与骨质退化，恶化或变性如牙周病，骨关节炎和转移性骨病以及溶骨性骨病相关的病症。还提供了可用于实施本发明方法的包含至少一种拆分的药物组合物和试剂盒。

10. 发明授权

US08636986B2 Treatment and prevention of bone loss using resolvins 有权
标题翻译：使用溶解剂治疗和预防骨质流失
公开(公告)号：US08636986B2
公开(公告)日：2014-01-28
申请号：US12094016
申请日：2006-11-17
申请人： Thomas E. Van Dyke
发明人： Thomas E. Van Dyke
IPC分类号： A61K8/00
CPC分类号： A61K31/202 , A61K31/22 , A61K31/557 , A61K31/663 , A61K45/06 , A61K2300/00
摘要： The present invention provides new methods for inducing or promoting bone growth and/or for reducing or preventing bone deterioration in a mammal subject. The inventive methods generally comprise administering to the subject an effective amount of a resolvin. In particular, the inventive methods may be useful for treating or preventing conditions associated with bone degradation, deterioration or degeneration such as periodontal disease, osteoarthritis, and metastatic bone disease and osteolytic bone disease. Pharmaceutical compositions and kits comprising at least one resolvin are also provided that can be used to performed the inventive methods.
摘要翻译：本发明提供用于诱导或促进骨生长和/或用于减少或预防哺乳动物受试者的骨质退化的新方法。本发明的方法通常包括向受试者施用有效量的阿维生素。特别地，本发明的方法可用于治疗或预防与骨质退化，恶化或变性如牙周病，骨关节炎和转移性骨病以及溶骨性骨病相关的病症。还提供了可用于实施本发明的方法的药物组合物和包含至少一种阿维生素的试剂盒。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式