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1. 发明授权

US06180056B2 Method and compositions for minimizing biological and colloidal fouling 失效
标题翻译：用于最小化生物和胶体结垢的方法和组合物
公开(公告)号：US06180056B2
公开(公告)日：2001-01-30
申请号：US09208473
申请日：1998-12-10
申请人： Thomas E. McNeel , Daniel L. Comstock , Maryam Z. Anstead , Richard A. Clark
发明人： Thomas E. McNeel , Daniel L. Comstock , Maryam Z. Anstead , Richard A. Clark
IPC分类号： C23F1402
CPC分类号： C02F1/50 , B01D61/025 , B01D61/027 , B01D61/04 , B01D61/145 , B01D61/147 , B01D61/16 , B01D2311/04 , B01D2311/12 , B01D2311/16 , C02F5/08
摘要： A composition for minimizing biological and/or colloidal fouling is described, which includes an anionic antiscalant and a cationically charged biocide. Further, a method of controlling fouling is described and achieved by introducing a formulation of the present invention into an aqueous system which uses a separation membrane. The compositions used in the present invention are compatible with such separation systems and preferably prevent membrane fouling.
摘要翻译：描述了用于最小化生物和/或胶体结垢的组合物，其包括阴离子防垢剂和阳离子电荷的杀生物剂。此外，通过将本发明的制剂引入使用分离膜的水性体系来描述和实现控制结垢的方法。用于本发明的组合物与这种分离系统相容，并且优选防止膜污染。

2. 发明申请

US20130043194A1 Tagged Polymers, Water Treatment Compositions, And Methods Of Their Use In Aqueous Systems 有权
标题翻译：标签聚合物，水处理组合物及其在水系统中的使用方法
公开(公告)号：US20130043194A1
公开(公告)日：2013-02-21
申请号：US13561455
申请日：2012-07-30
申请人： Thomas E. McNeel , Marilyn S. Whittemore , Richard A. Clark , Jadwiga J. Grabowicz
发明人： Thomas E. McNeel , Marilyn S. Whittemore , Richard A. Clark , Jadwiga J. Grabowicz
IPC分类号： C08F26/06 , C02F1/00
CPC分类号： G01N33/1826 , C02F1/008 , C02F1/5209 , C02F2209/06 , C02F2303/20 , C09K11/06 , G01N33/18 , Y02A20/206 , Y10S210/917 , Y10T436/13
摘要： A method and composition is described for controlling the growth of fouling materials, such as scale, in aqueous systems using a tagged (fluorescent) polymer. The tagged polymer can be a fluorescent polymer which has at least one fluorescent monomeric unit derived from a fluorophore which has at least one terminal end comprising an olefinic group. The method of controlling the growth of at least one fouling material in an aqueous system can include the steps of adding the tagged polymer to the aqueous system to be treated, fluorometrically monitoring the concentration of the tagged polymer, and adjusting, as needed, the concentration of the tagged polymer and proportionally used water treatment compound or compounds effective to control the growth of at least one fouling material. The adjustment of pH before determination of the fluorescence signal can be employed to increase sensitivity of the fluorophore and minimize background interference.
摘要翻译：描述了一种方法和组合物，用于使用标记（荧光）聚合物在含水体系中控制污垢物质如水垢的生长。标记的聚合物可以是具有至少一种衍生自荧光团的荧光单体单元的荧光聚合物，该荧光团具有至少一个包含烯属基团的末端。控制水性体系中至少一种结垢材料的生长的方法可以包括以下步骤：将标记的聚合物加入待处理的水性体系中，荧光测量监测标记的聚合物的浓度，并根据需要调节浓度的标记聚合物和成比例地使用的水处理化合物或有效控制至少一种结垢材料生长的化合物。荧光信号测定前pH值的调节可用于提高荧光团的灵敏度，并使背景干扰最小化。

3. 发明授权

US08951960B2 Synergistic combination of DBNPA and polycyclic antibacterial peptide as biocide in bioethanol production 有权
标题翻译： DBNPA和多环抗菌肽在生物乙醇生产中的协同增效作为杀生物剂
公开(公告)号：US08951960B2
公开(公告)日：2015-02-10
申请号：US13048972
申请日：2011-03-16
申请人： Christopher L. Wiatr , Michael L. Corcoran , Thomas E. McNeel , Richard A. Clark , Rita de Cassia Bortoto Porto , David Oppong
发明人： Christopher L. Wiatr , Michael L. Corcoran , Thomas E. McNeel , Richard A. Clark , Rita de Cassia Bortoto Porto , David Oppong
IPC分类号： A23K1/06 , A01N37/18 , A01N37/34 , C12P7/06 , A01P1/00 , C07K14/195 , A23K1/14 , A01N31/02 , A01N63/02
CPC分类号： A01N37/34 , A01N31/02 , A01N63/02 , A23K10/37 , A23K10/38 , B01D3/002 , C07K14/195 , C12P7/06 , Y02E50/16 , Y02E50/17 , Y02P20/582 , Y02P60/873 , A01N2300/00 , A01N33/12 , A01N33/18 , A01N33/20 , A01N35/02 , A01N35/08 , A01N37/16 , A01N43/80 , A01N43/88 , A01N47/14 , A01N47/44 , A01N47/48 , A01N57/34 , A01N59/00
摘要： Methods for controlling the growth of bacteria in ethanol fermentation systems with antibiotic alternatives, which can be nonoxidizing biocides, stabilized oxidizers, or any combinations thereof, are described. As an option, a process or composition of the present invention can include one or more polycyclic antibacterial peptides. The methods can provide improvements, such as increased ethanol yields with minimal carryover of biocide into co-products of the processes.
摘要翻译：描述了用抗生素替代物（其可以是非氧化杀生物剂，稳定的氧化剂或其任何组合）来控制乙醇发酵系统中细菌生长的方法。作为选择，本发明的方法或组合物可以包括一种或多种多环抗菌肽。这些方法可以提供改进，例如提高乙醇产率，同时将杀生物剂最少携带到工艺的共同产品中。

4. 发明授权

US09347928B2 Tagged polymers, water treatment compositions, and methods of their use in aqueous systems 有权
标题翻译：标签聚合物，水处理组合物及其在含水体系中的使用方法
公开(公告)号：US09347928B2
公开(公告)日：2016-05-24
申请号：US13561455
申请日：2012-07-30
申请人： Thomas E. McNeel , Marilyn S. Whittemore , Richard A. Clark , Jadwiga J. Grabowicz
发明人： Thomas E. McNeel , Marilyn S. Whittemore , Richard A. Clark , Jadwiga J. Grabowicz
IPC分类号： C02F1/52 , G01N33/18 , C09K11/06 , C02F1/00
CPC分类号： G01N33/1826 , C02F1/008 , C02F1/5209 , C02F2209/06 , C02F2303/20 , C09K11/06 , G01N33/18 , Y02A20/206 , Y10S210/917 , Y10T436/13
摘要： A method and composition is described for controlling the growth of fouling materials, such as scale, in aqueous systems using a tagged (fluorescent) polymer. The tagged polymer can be a fluorescent polymer which has at least one fluorescent monomeric unit derived from a fluorophore which has at least one terminal end comprising an olefinic group. The method of controlling the growth of at least one fouling material in an aqueous system can include the steps of adding the tagged polymer to the aqueous system to be treated, fluorometrically monitoring the concentration of the tagged polymer, and adjusting, as needed, the concentration of the tagged polymer and proportionally used water treatment compound or compounds effective to control the growth of at least one fouling material. The adjustment of pH before determination of the fluorescence signal can be employed to increase sensitivity of the fluorophore and minimize background interference.
摘要翻译：描述了一种方法和组合物，用于使用标记（荧光）聚合物在含水体系中控制污垢物质如水垢的生长。标记的聚合物可以是具有至少一种衍生自荧光团的荧光单体单元的荧光聚合物，其具有至少一个包含烯属基团的末端。控制水性体系中至少一种结垢材料的生长的方法可以包括以下步骤：将标记的聚合物加入待处理的水性体系中，荧光测量监测标记的聚合物的浓度，并根据需要调节浓度的标记聚合物和成比例地使用的水处理化合物或有效控制至少一种结垢材料生长的化合物。荧光信号测定前pH值的调节可用于提高荧光团的灵敏度，并使背景干扰最小化。

5. 发明申请

US20110230394A1 Processes Using Antibiotic Alternatives In Bioethanol Production 有权
标题翻译：在生物乙醇生产中使用抗生素替代物的方法
公开(公告)号：US20110230394A1
公开(公告)日：2011-09-22
申请号：US13048972
申请日：2011-03-16
申请人： Christopher L. Wiatr , Michael L. Corcoran , Thomas E. McNeel , Richard A. Clark , Rita de Cassia Bortoto Porto , David Oppong
发明人： Christopher L. Wiatr , Michael L. Corcoran , Thomas E. McNeel , Richard A. Clark , Rita de Cassia Bortoto Porto , David Oppong
IPC分类号： A01N37/18 , C12P7/06 , A01P1/00 , A23L1/105 , A23K1/06
CPC分类号： A01N37/34 , A01N31/02 , A01N63/02 , A23K10/37 , A23K10/38 , B01D3/002 , C07K14/195 , C12P7/06 , Y02E50/16 , Y02E50/17 , Y02P20/582 , Y02P60/873 , A01N2300/00 , A01N33/12 , A01N33/18 , A01N33/20 , A01N35/02 , A01N35/08 , A01N37/16 , A01N43/80 , A01N43/88 , A01N47/14 , A01N47/44 , A01N47/48 , A01N57/34 , A01N59/00
摘要： Methods for controlling the growth of bacteria in ethanol fermentation systems with antibiotic alternatives, which can be nonoxidizing biocides, stabilized oxidizers, or any combinations thereof, are described. As an option, a process or composition of the present invention can include one or more polycyclic antibacterial peptides. The methods can provide improvements, such as increased ethanol yields with minimal carryover of biocide into co-products of the processes.
摘要翻译：描述了用抗生素替代物（其可以是非氧化杀生物剂，稳定的氧化剂或其任何组合）来控制乙醇发酵系统中细菌生长的方法。作为选择，本发明的方法或组合物可以包括一种或多种多环抗菌肽。这些方法可以提供改进，例如提高乙醇产率，同时将杀生物剂最少携带到工艺的共同产品中。

6. 发明授权

US06311546B1 Biofouling monitor and methods to monitor or detect biofouling 失效
标题翻译：生物污染监测器和监测或检测生物污垢的方法
公开(公告)号：US06311546B1
公开(公告)日：2001-11-06
申请号：US09209453
申请日：1998-12-11
申请人： Wayne H. Dickinson , Thomas E. McNeel , Richard A. Clark , E. Van Haute
发明人： Wayne H. Dickinson , Thomas E. McNeel , Richard A. Clark , E. Van Haute
IPC分类号： G01M302
CPC分类号： G01N17/00
摘要： A biofouling monitor is described which has a column having an inlet and an outlet; a microorganism nutrient feed line located upstream of the inlet; and a first pressure sensor located upstream of the inlet for measuring flow pressure and a second pressure system located downstream of the outlet for measuring flow pressure. Also described is a biofouling monitor which further has a recirculation system and optionally inert packing material located in the column. A method to monitor or detect biofouling ahead of time in an aqueous system is further described.
摘要翻译：描述了一种具有入口和出口的柱的生物污垢监测器; 位于入口上游的微生物营养供料管线; 以及位于所述入口上游的用于测量流压的第一压力传感器和位于所述出口下游的用于测量流量压力的第二压力系统。还描述了一种生物污垢监测器，其还具有位于该塔中的再循环系统和任选的惰性包装材料。进一步描述在水系统中提前监测或检测生物污损的方法。

7. 发明授权

US07563991B2 All weather housing assembly for electronic components 有权
标题翻译：电子元件的所有天气住宅组件
公开(公告)号：US07563991B2
公开(公告)日：2009-07-21
申请号：US11423127
申请日：2006-06-08
申请人： Robert W. Twitchell, Jr. , Richard A. Clark
发明人： Robert W. Twitchell, Jr. , Richard A. Clark
IPC分类号： H01R13/502 , H01L23/02 , H05K5/06
CPC分类号： H05K5/0004 , Y02D70/10 , Y10T29/49117 , Y10T29/4973 , Y10T29/49817
摘要： An all weather housing assembly for protection of electrical components includes a first housing having an open end and defining a first compartment for receipt therein of electronic components; a cover attached to the first housing for enclosing the first compartment, the cover further including a mounting structure for receiving and retaining a power source which structure is mounted on a side of the cover that is exterior to the enclosed first compartment; and a second housing having an open end and defining a second compartment that is dimensioned to cover and protect a power source when received and retained by the mounting structure of the cover, the second housing being connected to the first housing independent of the attachment of the cover to the first housing.
摘要翻译：用于保护电气部件的全天候外壳组件包括具有开口端并限定用于在其中接收电子部件的第一隔室的第一壳体; 盖子，其附接到所述第一壳体以封闭所述第一隔室，所述盖子还包括用于接收和保持电源的安装结构，所述电源安装在所述封盖的封闭的第一隔间外部的一侧; 以及第二壳体，其具有开口端并且限定第二隔室，其尺寸被设计成在由盖的安装结构接收和保持时覆盖和保护电源，所述第二壳体与第一壳体的连接无关，覆盖到第一个房屋。

8. 发明申请

US20090111738A1 FIBRONECTIN POLYPEPTIDES AND METHODS OF USE 有权
标题翻译：纤维蛋白多糖和使用方法
公开(公告)号：US20090111738A1
公开(公告)日：2009-04-30
申请号：US12089291
申请日：2006-10-04
申请人： Richard A. Clark , Xiang-Dong Ren , Fubao Lin
发明人： Richard A. Clark , Xiang-Dong Ren , Fubao Lin
IPC分类号： A61K38/39 , C07K14/78 , C07H21/04 , A61P35/04 , C07K7/08
CPC分类号： A61Q19/00 , A61K8/02 , A61K8/64 , A61K38/00 , A61K45/06 , A61K48/00 , A61K2800/24 , A61Q17/04 , A61Q19/001 , C07K14/78
摘要： Described herein are fragments of fibronectin and variants thereof that bind growth factors. Compositions containing such a fragment of fibronectin are therefore useful in sequestering growth factors, and complexes containing both a FN fragment and a bound, active growth factor can be used to deliver growth factors to a patient (e.g., to a wound on the patient's skin).
摘要翻译：本文描述了结合生长因子的纤连蛋白及其变体的片段。因此，含有这种纤连蛋白片段的组合物可用于螯合生长因子，并且可以使用含有FN片段和结合的活性生长因子的复合物将生长因子递送至患者（例如，对患者皮肤上的伤口）。

9. 发明授权

US07183502B1 Extendable channel unit containing a conductor 失效
标题翻译：包含导体的可扩展通道单元
公开(公告)号：US07183502B1
公开(公告)日：2007-02-27
申请号：US11409815
申请日：2006-04-24
申请人： David H. Johnston , Richard A. Clark
发明人： David H. Johnston , Richard A. Clark
IPC分类号： H02G3/04
CPC分类号： H02G3/0487 , H02G3/0431 , H02G3/0608
摘要： An extendable channel unit such as molding unit (21) has a pair of telescopically arranged relatively extendable conduits (55, 75) with a conductor (22) interconnected in conductive relation between the conduits, with an intermediate section (137) of the conductor effective to accommodate the relative extension of the conduits. The intermediate section may include a sinuous configuration (133) or expandable coils (139). The channel unit may be installed along a wall (145) or other surface for decoratively covering the installation of the conductor for connection with an operated device (153). The channel unit may be installed into an extendable ramp (163) when installed along a floor, such as within a doorway (171). Two joints (308, 310) provide freedom of rotation about the conductor axis on opposed sides of an angled joint (312) that provides freedom of rotation about an axis disposed at a 45° angle to the axis of the conductor. This combination permits the unit to be configured to pass around both inside and outside corners, as well as to form upward and downward right angles along a straight wall.
摘要翻译：诸如模制单元（21）的可延伸通道单元具有一对可伸缩布置的相对可延伸的导管（55,75），导体（22）在导管之间以导电关系相互连接，导体的中间部分（137）有效以适应导管的相对延伸。中间部分可以包括弯曲构造（133）或可扩展线圈（139）。通道单元可以沿着壁（145）或其他表面安装，用于装饰地覆盖用于与被操作的装置（153）连接的导体的安装。当沿着诸如门口（171）内的地板安装时，通道单元可以被安装到可延伸斜坡（163）中。两个接头（308,310）在成角度接头（312）的相对侧上提供围绕导体轴线的旋转自由度，其提供围绕与导体轴线成45°角设置的轴的旋转自由度。这种组合允许单元被配置成绕内角和外角通过，并且沿直壁形成向上和向下的直角。

10. 发明授权

US5866016A Methods and compositions for controlling biofouling using combinations of an ionene polymer and a salt of dodecylamine 失效
标题翻译：使用紫罗烯聚合物和十二烷基胺盐的组合来控制生物污损的方法和组合物
公开(公告)号：US5866016A
公开(公告)日：1999-02-02
申请号：US886548
申请日：1997-07-01
申请人： Percy A. Jaquess , Luis Fernando Del Corral , Richard A. Clark
发明人： Percy A. Jaquess , Luis Fernando Del Corral , Richard A. Clark
IPC分类号： A01N33/12 , A01N43/40 , C02F1/50 , C09D5/14 , A01N33/04 , A61K7/22 , C02F1/68
CPC分类号： C09D5/14 , A01N33/12 , A01N43/40 , C02F1/50 , Y10S210/931
摘要： The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an ionene polymer and a salt of dodecylamine in a combined amount effective to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an ionene polymer and a salt of dodecylamine in a combined amount effective to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the fouling organisms. The present invention also relates to compositions containing an ionene polymer and a salt of dodecylamine and useable in the above methods. The compositions comprise an ionene polymer and a salt of dodecylamine in a combined amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.
摘要翻译：本发明涉及一种抑制细菌粘附在潜水表面上的方法。该方法用阴离子聚合物和十二烷胺的盐接触潜水表面，其组合量有效地抑制细菌粘附到潜水表面。本发明还涉及一种用于控制水系统的生物污垢的方法。该方法以有效抑制细菌粘附到水系统内的浸没表面的组合量加入紫罗烯聚合物和十二烷基胺盐。该方法有效地控制生物污染，而不会基本上杀死污染的生物体。本发明还涉及含有紫罗烯聚合物和十二烷基胺盐的组合物，可用于上述方法。组合物包含有效抑制细菌粘附到潜水或浸没表面的组合量的紫罗烯聚合物和十二烷基胺盐。

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