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1. 发明申请

US20090009166A1 METHOD OF USING G-MATRIX FOURIER TRANSFORMATION NUCLEAR MAGNETIC RESONANCE (GFT NMR) SPECTROSCOPY FOR RAPID CHEMICAL SHIFT ASSIGNMENT AND SECONDARY STRUCTURE DETERMINATION OF PROTEINS 有权
标题翻译：使用G-MATRIX FOURIER转换核磁共振（GFT NMR）光谱法进行快速化学转移分配和二级结构测定蛋白质的方法
公开(公告)号：US20090009166A1
公开(公告)日：2009-01-08
申请号：US12057076
申请日：2008-03-27
申请人： Thomas A. Szyperski , Seho Kim , Hanudatta S. Atreya
发明人： Thomas A. Szyperski , Seho Kim , Hanudatta S. Atreya
IPC分类号： G01R33/54 , G01N24/08
CPC分类号： G01R33/4633 , G01R33/465 , Y10T436/24
摘要： The present invention presents a new approach to rapidly obtaining precise high-dimensional NMR spectral information, named “GFT NMR spectroscopy”, which is based on the phase sensitive joint sampling of the indirect dimensions spanning a subspace of a conventional NMR experiment. The phase-sensitive joint sampling of several indirect dimensions of a high-dimensional NMR experiment leads to largely reduced minimum measurement times when compared to FT NMR. This allows one to avoid the “sampling limited” data collection regime. Concomitantly, the analysis of the resulting chemical shift multiplets, which are edited by the G-matrix transformation, yields increased precision for the measurement of the chemical shifts. Additionally, methods of conducting specific GFT NMR experiments as well as methods of conducting a combination of GFT NMR experiments for rapidly obtaining precise chemical shift assignment and determining the structure of proteins or other molecules are disclosed.
摘要翻译：本发明提供了一种快速获得精确的高维NMR光谱信息的新方法，命名为“GFT NMR光谱”，其基于跨过常规NMR实验的子空间的间接尺寸的相敏联合采样。与FT NMR相比，高维NMR实验的几个间接尺寸的相敏联合取样导致最大测量时间大大降低。这样可以避免“采样受限”的数据收集制度。伴随地，通过G矩阵变换编辑的所得到的化学位移多重峰的分析产生了用于测量化学位移的增加的精度。此外，公开了进行特定GFT NMR实验的方法以及进行GFT NMR实验的组合以快速获得精确的化学位移分配和确定蛋白质或其他分子的结构的方法。

2. 发明授权

US06831459B2 Method of using G-matrix Fourier transformation nuclear magnetic resonance (GFT NMR) spectroscopy for rapid chemical shift assignment and secondary structure determination of proteins 有权
公开(公告)号：US06831459B2
公开(公告)日：2004-12-14
申请号：US10617482
申请日：2003-07-11
申请人： Thomas A. Szyperski , Seho Kim , Hanudatta S. Atreya
发明人： Thomas A. Szyperski , Seho Kim , Hanudatta S. Atreya
IPC分类号： G01V300
CPC分类号： G01R33/4633 , G01R33/465 , Y10T436/24
摘要： The present invention presents a new approach to rapidly obtaining precise high-dimensional NMR spectral information, named “GFT NMR spectroscopy”, which is based on the phase sensitive joint sampling of the indirect dimensions spanning a subspace of a conventional NMR experiment. The phase-sensitive joint sampling of several indirect dimensions of a high-dimensional NMR experiment leads to largely reduced minimum measurement times when compared to FT NMR. This allows one to avoid the “sampling limited” data collection regime. Concomitantly, the analysis of the resulting chemical shift multiplets, which are edited by the G-matrix transformation, yields increased precision for the measurement of the chemical shifts. Additionally, methods of conducting specific GFT NMR experiments as well as methods of conducting a combination of GFT NMR experiments for rapidly obtaining precise chemical shift assignment and determining the structure of proteins or other molecules are disclosed.

3. 发明授权

US07880468B2 Method of using G-matrix fourier transformation nuclear magnetic resonance (GFT NMR) spectroscopy for rapid chemical shift assignment and secondary structure determination of proteins 有权
标题翻译：使用G矩阵傅里叶变换核磁共振（GFT NMR）光谱法进行蛋白质快速化学位移分配和二级结构测定的方法
公开(公告)号：US07880468B2
公开(公告)日：2011-02-01
申请号：US12057076
申请日：2008-03-27
申请人： Thomas A. Szyperski , Seho Kim , Hanudatta S. Atreya
发明人： Thomas A. Szyperski , Seho Kim , Hanudatta S. Atreya
IPC分类号： G01V3/00
CPC分类号： G01R33/4633 , G01R33/465 , Y10T436/24
摘要： The present invention presents a new approach to rapidly obtaining precise high-dimensional NMR spectral information, named “GFT NMR spectroscopy”, which is based on the phase sensitive joint sampling of the indirect dimensions spanning a subspace of a conventional NMR experiment. The phase-sensitive joint sampling of several indirect dimensions of a high-dimensional NMR experiment leads to largely reduced minimum measurement times when compared to FT NMR. This allows one to avoid the “sampling limited” data collection regime. Concomitantly, the analysis of the resulting chemical shift multiplets, which are edited by the G-matrix transformation, yields increased precision for the measurement of the chemical shifts. Additionally, methods of conducting specific GFT NMR experiments as well as methods of conducting a combination of GFT NMR experiments for rapidly obtaining precise chemical shift assignment and determining the structure of proteins or other molecules are disclosed.
摘要翻译：本发明提供了一种快速获得精确的高维NMR光谱信息的新方法，命名为“GFT NMR光谱”，其基于跨过常规NMR实验的子空间的间接尺寸的相敏联合采样。与FT NMR相比，高维NMR实验的几个间接尺寸的相敏联合取样导致最大测量时间大大降低。这样可以避免“采样受限”的数据收集制度。伴随地，通过G矩阵变换编辑的所得到的化学位移多重峰的分析产生了用于测量化学位移的增加的精度。此外，公开了进行特定GFT NMR实验的方法以及进行GFT NMR实验的组合以快速获得精确的化学位移分配和确定蛋白质或其他分子的结构的方法。

4. 发明授权

US07365539B2 Method of using G-matrix fourier transformation nuclear magnetic resonance (GFT NMR) spectroscopy for rapid chemical shift assignment and secondary structure determination of proteins 失效
标题翻译：使用G矩阵傅里叶变换核磁共振（GFT NMR）光谱法进行蛋白质快速化学位移分配和二级结构测定的方法
公开(公告)号：US07365539B2
公开(公告)日：2008-04-29
申请号：US10973807
申请日：2004-10-26
申请人： Thomas A. Szyperski , Seho Kim , Hanudatta S. Atreya
发明人： Thomas A. Szyperski , Seho Kim , Hanudatta S. Atreya
IPC分类号： G01V3/00
CPC分类号： G01R33/4633 , G01R33/465 , Y10T436/24
摘要： The present invention presents a new approach to rapidly obtaining precise high-dimensional NMR spectral information, named “GFT NMR spectroscopy”, which is based on the phase sensitive joint sampling of the indirect dimensions spanning a subspace of a conventional NMR experiment. The phase-sensitive joint sampling of several indirect dimensions of a high-dimensional NMR experiment leads to largely reduced minimum measurement times when compared to FT NMR. This allows one to avoid the “sampling limited” data collection regime. Concomitantly, the analysis of the resulting checmical shift multiplets, which are edited by the G-matrix transformation, yields increased precision for the measurement of the chemical shifts. Additionally, methods of conducting specific GFT NMR experiments as well as methods of conducting a combination of GFT NMR experiments for rapidly obtaining precise chemical shift assignment and determining the structure of proteins or other molecules are disclosed.
摘要翻译：本发明提出了一种快速获得精确的高维NMR光谱信息的新方法，命名为“GFT NMR光谱”，其基于跨过常规NMR实验的子空间的间接尺寸的相敏联合采样。与FT NMR相比，高维NMR实验的几个间接尺寸的相敏联合取样导致最大测量时间大大降低。这样可以避免“采样受限”的数据收集制度。伴随地，通过G矩阵变换编辑的所得到的移动多重点的分析产生了用于化学位移测量的增加的精度。此外，公开了进行特定GFT NMR实验的方法以及进行GFT NMR实验的组合以快速获得精确的化学位移分配和确定蛋白质或其他分子的结构的方法。

5. 发明授权

US07396685B2 Phase sensitively-detected reduced dimensionality nuclear magnetic resonance spectroscopy for rapid chemical shift assignment and secondary structure determination of proteins 失效
标题翻译：相位敏感检测降低维度核磁共振波谱用于蛋白质的快速化学位移分配和二级结构测定
公开(公告)号：US07396685B2
公开(公告)日：2008-07-08
申请号：US10628818
申请日：2003-07-28
申请人： Thomas A. Szyperski , Seho Kim
发明人： Thomas A. Szyperski , Seho Kim
IPC分类号： G01N24/00
CPC分类号： G01R33/4633 , G01R33/465 , Y10T436/24
摘要： The present invention discloses eleven reduced dimensionality (RD) triple resonance nuclear magnetic resonance (NMR) experiments for measuring chemical shift values of certain nuclei in a protein molecule, where the chemical shift values encoded in a peak pair of an NMR spectrum are detected in a phase sensitive manner. The RD 3D HA,CA,(CO),N,HN NMR and RD 3D H,C,(C-TOCSY-CO),N,HN NMR experiments are designed to yield “sequential” connectivities, while the RD 3D Hα/β,Cα/β,CO,HA NMR and RD 3D Hα/β,Cα/β,N,HN NMR experiments provide “intraresidue” connectivities. The RD 3D H,C,C,H-COSY NMR, RD 3D H,C,C,H-TOCSY NMR, and RD 2D H,C,H-COSY NMR experiments allow one to obtain assignments for aliphatic and aromatic side chain chemical shifts, while the RD 2D HB,CB,(CG,CD),HD NMR experiment provide information for the aromatic side chain chemical shifts. In addition, methods of conducting suites of RD triple resonance NMR experiments for high-throughput resonance assignment of proteins and determination of secondary structure elements are disclosed.
摘要翻译：本发明公开了一种用于测量蛋白质分子中某些核的化学位移值的十一维三维共振核磁共振（NMR）实验，其中在一个核磁共振谱的峰对中编码的化学位移值在相位敏感的方式。 CA，（CO），N，HN NMR和RD 3D H， Hα/β， CO，HA NMR和RD 3D Hα/β， N，1 H NMR实验提供“残留”连接。 C，C，H-COZY NMR，RD 3D H， H， C，C，H-TOCSY NMR和RD 2D H， HB，（UC，CD），HD NMR实验提供了芳族侧链化学位移的信息。此外，公开了用于蛋白质的高通量共振分配的RD三重共振NMR实验的套件的方法和二级结构元件的测定。

6. 发明申请

US20090115414A1 PHASE-SENSITIVELY DETECTED REDUCED DIMENSIONALITY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY FOR RAPID CHEMICAL SHIFT ASSIGNMENT AND SECONDARY STRUCTURE DETERMINATION OF PROTEINS 审中-公开
标题翻译：相敏检测减少尺寸核激光共振光谱快速化学转移分配和二级结构测定蛋白质
公开(公告)号：US20090115414A1
公开(公告)日：2009-05-07
申请号：US12132320
申请日：2008-06-03
申请人： Thomas A. Szyperski , Seho Kim
发明人： Thomas A. Szyperski , Seho Kim
IPC分类号： G01R33/44
CPC分类号： G01R33/4633 , G01R33/465 , Y10T436/24
摘要： The present invention discloses eleven reduced dimensionality (RD) triple resonance nuclear magnetic resonance (NMR) experiments for measuring chemical shift values of certain nuclei in a protein molecule, where the chemical shift values encoded in a peak pair of an NMR spectrum are detected in a phase sensitive manner. The RD 3D HA,CA,(CO),N,HN NMR and RD 3D H,C,(C-TOCSY-CO),N,HN NMR experiments are designed to yield “sequential” connectivities, while the RD 3D Hα/β,Cα/β, CO,HA NMR and RD 3D Hα/β,Cα/β,N,HN NMR experiments provide “intraresidue” connectivities. The RD 3D H,C,C,H-COSY NMR, RD 3D H,C,C,H-TOCSY NMR, and RD 2D H,C,H-COSY NMR experiments allow one to obtain assignments for aliphatic and aromatic side chain chemical shifts, while the RD 2D HB,CB,(CG,CD),HD NMR experiment provide information for the aromatic side chain chemical shifts. In addition, methods of conducting suites of RD triple resonance NMR experiments for high-throughput resonance assignment of proteins and determination of secondary structure elements are disclosed.
摘要翻译：本发明公开了一种用于测量蛋白质分子中某些核的化学位移值的十一维三维共振核磁共振（NMR）实验，其中在一个核磁共振谱的峰对中编码的化学位移值在相位敏感的方式。 HA，CA，（CO），N，HN NMR和RD 3D H，单独的 “C，（C-TOCSY-CO），N，HN NMR实验被设计为产生”顺序“连接，而RD 3D Hal /β， Calpha / beta，CO，HA NMR和RD 3D氦/氦，Calpha /β，N，HN NMR实验提供了“残留”连接。 RD 3D H，C，C，H-COZY NMR，RD 3D，H， C，C，H-TOCSY NMR和RD 2D H，C，H-COZY NMR实验允许获得脂族和芳族侧链化学位移的分配，而DB 2D，CB，（CG，CD），HD NMR实验提供了芳族侧链化学位移的信息。此外，公开了用于蛋白质的高通量共振分配的RD三重共振NMR实验的套件的方法和二级结构元件的测定。

7. 发明授权

US08920008B2 Shield actuator for head lamp in the vehicle 有权
标题翻译：用于车辆前照灯的屏蔽执行器
公开(公告)号：US08920008B2
公开(公告)日：2014-12-30
申请号：US13575506
申请日：2010-11-22
申请人： Seho Kim
发明人： Seho Kim
IPC分类号： F21V7/00 , B60Q1/076
CPC分类号： B60Q1/076 , F21S41/689 , F21S41/698 , H02K7/116 , Y10T74/188
摘要： Disclosed is a vehicle head lamp-purpose shield actuator, including a case, and a motor fixed inside the case, and a first rotating shaft rotated by the motor to be connected to an output shaft that drives a shield member for controlling an opening angle of a head lamp, and a second rotating shaft disposed inside the case to be connected to an output shaft that drives a shield member for opening the shield member, wherein the case is constructed by an inter-coupling of a left side case and a right side case, and the left side case and right side case each having a shaft connection part connecting a first rotating shaft and a second rotating shaft, and an output shaft, respectively, thereby being used commonly in a left side head lamp and a right side head lamp, and consequently improving productivity and assembling capacity and reducing production expense.
摘要翻译：本发明公开了一种车载灯具用屏蔽致动器，包括壳体和固定在壳体内的电动机，以及由马达旋转以连接到输出轴的第一旋转轴，驱动屏蔽构件用于控制开启角度一个头灯和一个设置在壳体内的第二旋转轴，以连接到驱动用于打开屏蔽构件的屏蔽构件的输出轴，其中壳体通过左侧壳体和右侧的相互连接构成壳体和分别具有连接第一旋转轴和第二旋转轴的轴连接部分的左侧壳体和右侧壳体以及输出轴，从而被共同地用于左侧头灯和右侧头部灯，从而提高生产率和组装能力，降低生产成本。

8. 发明授权

US09219812B2 Mobile terminal 有权
标题翻译：移动终端
公开(公告)号：US09219812B2
公开(公告)日：2015-12-22
申请号：US13553674
申请日：2012-07-19
申请人： Seho Kim , Yeonhwa Lee , Byeonghak Jung , Youngsun Park
发明人： Seho Kim , Yeonhwa Lee , Byeonghak Jung , Youngsun Park
IPC分类号： H04M1/725
CPC分类号： H04M1/72583 , G06F3/04817 , G06F3/0482 , G06F3/04842 , G06F3/0486 , G06F2203/04803 , G06F2203/04804 , G06F2203/04808 , H04M1/72544
摘要： A mobile terminal is disclosed. The mobile terminal may include a display module and a controller. The display module displays a plurality of icons on a background thereof. The controller changes the background to a specific background predetermined for a specific icon upon selection of the specific icon from the plurality of icons, and executes a specific application corresponding to the specific icon using information corresponding to a specific region of the changed background when the selected specific icon is moved to the specific region.
摘要翻译：公开了一种移动终端。移动终端可以包括显示模块和控制器。显示模块在其背景上显示多个图标。当从多个图标中选择特定图标时，控制器将背景改变为针对特定图标预定的特定背景，并且当所选择的图像使用与改变背景的特定区域相对应的信息时，执行与特定图标相对应的特定应用特定图标被移动到特定区域。

9. 发明申请

US20140035846A1 MOBILE TERMINAL AND CONTROLLING METHOD THEREOF 审中-公开
标题翻译：移动终端及其控制方法
公开(公告)号：US20140035846A1
公开(公告)日：2014-02-06
申请号：US13931217
申请日：2013-06-28
申请人： Yeonhwa LEE , Seho Kim
发明人： Yeonhwa LEE , Seho Kim
IPC分类号： G06F3/0488
CPC分类号： G06F3/0488 , G06F3/04886
摘要： A mobile terminal and controlling method thereof are disclosed, which flexibly utilizes a display screen space of a mobile terminal in consideration of user's convenience and necessity. The present invention includes a touchscreen configured to display a main screen including at least one object, a memory configured to store an action corresponding to the at least one object, and a controller, if at least one of the at least one object is selected by a 1st touch input to the touchscreen and an action display region is designated within the main screen by a 2nd touch input, controlling an active action screen for the selected object to be displayed within the action display region.
摘要翻译：公开了一种移动终端及其控制方法，其考虑到用户的便利性和必要性，灵活地利用移动终端的显示屏空间。本发明包括触摸屏，被配置为显示包括至少一个对象的主屏幕，被配置为存储与至少一个对象相对应的动作的存储器和控制器，如果至少一个对象中的至少一个被通过第二触摸输入在主屏幕内指定触摸屏的第一触摸输入和动作显示区域，控制要在动作显示区域内显示的所选对象的主动动作画面。

10. 发明申请

US20130019704A1 Linear Step Motor 有权
标题翻译：线性步进电机
公开(公告)号：US20130019704A1
公开(公告)日：2013-01-24
申请号：US13483798
申请日：2012-05-30
申请人： Seho Kim
发明人： Seho Kim
IPC分类号： F16H25/24
CPC分类号： H02K37/14 , F16C35/063 , H02K7/003 , H02K7/06 , H02K7/085 , Y10T74/18584 , Y10T74/186 , Y10T74/18664 , Y10T74/18688
摘要： Provided is a linear step motor, the motor including: a motor housing fixedly mounted at an inner surface of a ring-shaped stator and formed with an opening; a rotor rotatably mounted at a space centrally formed at the stator; a cover member coupled to a bearing to open/close the opening; a nut shaft centrally arranged at the rotor, coupled to an outside of the cover member by passing through a shaft hole centrally formed at an inner ring of the bearing, coupled at a periphery by a magnet and formed with a female screw gear-combined with a lead screw member formed at an inner surface with a male screw; and a fixing unit integrally formed with the nut shaft and fixed to the bearing coupled to the cover member.
摘要翻译：本发明提供线性步进电动机，该电动机包括：固定地安装在环形定子的内表面并形成开口的电动机壳体; 可旋转地安装在定子中心形成的空间的转子; 联接到轴承以打开/关闭所述开口的盖构件; 中心地布置在转子处的螺母轴通过中心形成在轴承的内圈上的轴孔联接到盖构件的外部，轴孔在周边处由磁体联接并形成有与内螺纹齿轮组合的内螺纹齿轮导螺杆构件，在内表面上形成有外螺纹; 以及固定单元，与所述螺母轴一体地形成并且固定到联接到所述盖构件的轴承。

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