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1. 发明申请

WO2019136081A1 SAMPLING DEVICE FOR DRUG DEVELOPMENT AND DIAGNOSIS OF GASTRIC-INTESTINAL DISEASES 审中-公开
公开(公告)号：WO2019136081A1
公开(公告)日：2019-07-11
申请号：PCT/US2019/012073
申请日：2019-01-02
申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN
发明人： SUN, Duxin , GIANCHANDANI, Yogesh B. , LI, Tao , LIAO, Jinhui , CHENG, Qisen , LEWIS, Johnathan , MEREDITH, Ryan , FELTON, Jeremy
IPC分类号： A61B5/00
摘要： An ingestible electronic capsule for the collection of samples along a gastric intestinal tract and methods relating thereto are provided. The ingestible electronic capsule includes a housing and a cap that form an interior chamber. The cap includes a sampling port and one or more sample collection chambers are disposed within the interior chamber. A motor is also disposed within the interior chamber and is configured to rotate one of the cap and the one or more sample collection chambers so to align one or the one or more sample collection chambers and the sampling port of the cap so to allow for sample collection. A microcontroller is also disposed within the interior chamber and is in communication with at least the motor. The microcontroller is configured to control the selective alignment of the sampling port and one of the one or more sample collection chambers and induce gastric intestinal fluid sampling.

2. 发明申请

WO2014186720A2 INTEGRATED FLUIDIC SYSTEM FOR GAS CHROMATOGRAPHY 审中-公开
标题翻译：用于气相色谱的综合流体系统
公开(公告)号：WO2014186720A2
公开(公告)日：2014-11-20
申请号：PCT/US2014/038421
申请日：2014-05-16
申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN
发明人： GIANCHANDANI, Yogesh B. , QIN, Yutao
IPC分类号： G01N30/32
CPC分类号： G01N30/6095 , B01L3/502707 , B01L2200/12 , B01L2300/0887 , G01N30/08 , G01N30/32 , G01N30/88 , G01N2030/025 , G01N2030/085 , G01N2030/326 , G01N2030/328 , G01N2030/8881
摘要： A method is presented for fabricating a fluidic system for a gas chromatograph. The method includes: microfabricating a portion of a fluidic system of a gas chromatograph on a substrate using a first mask; microfabricating a portion of the fluidic system of the gas chromatograph using a second mask; and microfabricating a portion of the fluidic system of the gas chromatograph using a third mask, such that the first mask, the second mask and the third mask are different from each other and the microfabricating of the fluidic system of the gas chromatograph is completed using only the first, second and third masks.
摘要翻译：提出了一种用于制造用于气相色谱仪的流体系统的方法。该方法包括：使用第一掩模将气相色谱仪的流体系统的一部分微制造在衬底上; 使用第二掩模微气化气相色谱仪的流体系统的一部分; 并使用第三掩模对气相色谱仪的流体系统的一部分进行微制造，使得第一掩模，第二掩模和第三掩模彼此不同，并且仅使用气相色谱仪的流体系统的微加工完成第一，第二和第三个面具。

3. 发明申请

WO2022098361A1 AUTONOMOUS MICROSYSTEM FOR IMMERSION INTO FLUID 审中-公开
公开(公告)号：WO2022098361A1
公开(公告)日：2022-05-12
申请号：PCT/US2020/059333
申请日：2020-11-06
申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN , TOTAL S.E.
发明人： GIANCHANDANI, Yogesh B. , BENKEN, Alexander , VELLALURU, Neeharika , DUTTA, Partha , ORDONEZ-VARELA, John-Richard , LE-BEULZE, Aurelie , BOERO-ROLLO, Jean-Gregoire
IPC分类号： F16L55/26 , F16L55/28 , F16L55/32 , E21B47/06
摘要： In various aspects, the present disclosure provides an example autonomous microsystem for immersion into a fluid. The autonomous microsystem includes electronics, a power source, and a packaging system that surrounds the electronics and the power source. The electronics can be configured to sense and record one or more environmental conditions. The packaging system may include a deformable shell that defines an internal space and a plurality of filler particles disposed in the internal space and configured to control a density of the autonomous microsystem in relation to the fluid. The filler particles may comprise a low-density material having a bulk density greater than or equal to about 100 kg/m3 and less than or equal to about 1,000 kg/m3 and have a packing density greater than or equal to about 1011/m3 and less than or equal to about 1021/m3.

4. 发明申请

WO2013070954A1 DEVICES AND METHODS FOR ADAPTIVE MICRO-GAS CHROMATOGRAPHY 审中-公开
标题翻译：用于自适应微气体色谱的装置和方法
公开(公告)号：WO2013070954A1
公开(公告)日：2013-05-16
申请号：PCT/US2012/064207
申请日：2012-11-08
申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN
发明人： FAN, Xudong , GIANCHANDANI, Yogesh B. , LIU, Jing
IPC分类号： G01N30/02 , G01N30/62
CPC分类号： G01N30/461 , G01N30/46 , G01N30/463 , G01N30/465 , G01N30/466 , G01N30/468 , G01N30/6095 , G01N30/72
摘要： The present disclosure provides adaptive methods for gas chromatography analysis of a gas sample comprising one or more target analytes (such as a micro-gas chromatography) and adaptive gas chromatography devices for carrying out such analytical methods. Broadly, the system can regulate flow into a downstream chromatographic column by detecting one or more upstream conditions. For example, one adaptive chromatography device comprises a first column, a modulator component, and a second column. A first detector or sensor detects the presence of target analytes upstream from the second column, while a second detector detects the presence of target analytes eluted from the second column. The modulator component assembly is responsive to an output generated by the first detector and adaptively regulates fluid flow into the second column. Such adaptive chromatography (micro-GC) systems have higher separation speed, better analyte identification capability, and far greater energy savings.
摘要翻译：本公开提供了用于气体样品的气相色谱分析的自适应方法，所述气体样品包含一种或多种靶分析物（例如微气相色谱）和用于进行这种分析方法的适应性气相色谱装置。通常，系统可以通过检测一个或多个上游条件来调节流入下游色谱柱的流量。例如，一个自适应色谱装置包括第一列，调制器组件和第二列。第一检测器或传感器检测来自第二列上游的目标分析物的存在，而第二检测器检测从第二列洗脱的目标分析物的存在。调制器部件组件响应于由第一检测器产生的输出并且自适应地调节流入第二列的流体流。这种自适应色谱（micro-GC）系统具有更高的分离速度，更好的分析物识别能力和更大的能量节省。

5. 发明公开

EP4241011A1 AUTONOMOUS MICROSYSTEM FOR IMMERSION INTO FLUID 失效
公开(公告)号：EP4241011A1
公开(公告)日：2023-09-13
申请号：EP20960967.6
申请日：2020-11-06
申请人： The Regents Of The University Of Michigan , TOTALENERGIES ONETECH
发明人： GIANCHANDANI, Yogesh B. , BENKEN, Alexander , VELLALURU, Neeharika , DUTTA, Partha , ORDONEZ-VARELA, John-Richard , LE-BEULZE, Aurelie , BOERO-ROLLO, Jean-Gregoire
IPC分类号： F16L55/26 , F16L55/28 , F16L55/32 , E21B47/06

6. 发明公开

EP4038363A1 DISTRIBUTED PRESSURE MEASUREMENT SYSTEM FOR CORE FLOOD EXPERIMENTS 审中-公开
公开(公告)号：EP4038363A1
公开(公告)日：2022-08-10
申请号：EP20871474.1
申请日：2020-10-02
申请人： TOTAL SE , The Regents of The University of Michigan
发明人： GIANCHANDANI, Yogesh B. , LI, Tao , DUTTA, Partha , BENKEN, Alexander , ORDONEZ-VARELA, John-Richard
IPC分类号： G01N15/08 , E21B25/00 , E21B25/08 , G01N33/24

7. 发明公开

EP2997359A2 INTEGRATED FLUIDIC SYSTEM FOR GAS CHROMATOGRAPHY 审中-公开
标题翻译：整合流体系统FÜRDIE GASCHROMATOGRAFIE
公开(公告)号：EP2997359A2
公开(公告)日：2016-03-23
申请号：EP14728401.2
申请日：2014-05-16
申请人： The Regents of the University of Michigan
发明人： GIANCHANDANI, Yogesh B. , QIN, Yutao
IPC分类号： G01N30/32 , B01L3/00 , B81C1/00 , G01N30/60 , G01N30/88 , G01N30/08
CPC分类号： G01N30/6095 , B01L3/502707 , B01L2200/12 , B01L2300/0887 , G01N30/08 , G01N30/32 , G01N30/88 , G01N2030/025 , G01N2030/085 , G01N2030/326 , G01N2030/328 , G01N2030/8881
摘要： A method is presented for fabricating a fluidic system for a gas chromatograph. The method includes: microfabricating a portion of a fluidic system of a gas chromatograph on a substrate using a first mask; microfabricating a portion of the fluidic system of the gas chromatograph using a second mask; and microfabricating a portion of the fluidic system of the gas chromatograph using a third mask, such that the first mask, the second mask and the third mask are different from each other and the microfabricating of the fluidic system of the gas chromatograph is completed using only the first, second and third masks. A gas chromatograph wherein a microfabricated Knudsen pump is arranged to operate in a first direction to draw carrier gas into a preconcentrator and in a second direction to draw gas out of the preconcentrator.
摘要翻译：提出了一种用于制造气相色谱仪的流体系统的方法。该方法包括：使用第一掩模将一部分气相色谱仪的流体系统微调制在基板上; 使用第二掩模对气相色谱仪的流体系统的一部分进行微制造; 并使用第三掩模对气相色谱仪的流体系统的一部分进行微制造，使得第一掩模，第二掩模和第三掩模彼此不同，并且仅使用气相色谱仪的流体系统的微加工完成第一，第二和第三个面具。一种气相色谱仪，其中微制造的克努森泵被布置成沿第一方向操作以将载气吸入预浓缩器并沿第二方向将气体抽出预浓缩器。

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