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    • 8. 发明申请
    • High unsaponifiables and methods of using the same and its derivatives and uses thereof
    • 高不皂化物及其使用方法及其衍生物及用途
    • US20090191243A9
    • 2009-07-30
    • US10611775
    • 2003-06-30
    • John HillRobert KleimanJames BrownSambasivarao Koritala
    • John HillRobert KleimanJames BrownSambasivarao Koritala
    • A61K7/075A61K7/08A61K35/78A61K35/60
    • A61K36/185A61K8/042A61K8/361A61K8/922A61Q9/02A61Q19/00A61Q19/10
    • Materials with high levels of unsaponifiable matter, such as extracts from plants, result in Hydrolysates with unique properties. It has been found that the application of a hydrolysis process to materials, particularly materials with a high level of unsaponifiables (e.g., at least 6% by total weight of the material) produces a product with properties significantly different from those products resulting from the conventional saponification of materials with less than 6% by weight of unsaponifiables. The resulting Hydrolysates from the practice of the present invention are substantive, resisting both physical and aqueous-based removal from skin and hair, exhibit a very unique surfactant property, and are not foaming agents with water. Addition of extra alkali metal hydroxides to these Hydrolysates according to the present invention may thus be used to neutralized acidic gelling agents and thereby providing a gel with enhanced the performance for cosmetics and pharmaceuticals.
    • 具有高水平不皂化物质的物质,如植物提取物,导致具有独特性质的水解产物。 已经发现,将水解方法应用于材料,特别是具有高水平不可皂化物的材料(例如,材料的总重量至少为6%)产生具有与常规的那些产物显着不同的性能的产品 皂化不到6%(重量)的不皂化物的材料。 所得到的本发明实施例的水解产物是实质性的,抵抗从皮肤和毛发的物理和水性去除,表现出非常独特的表面活性剂性质,并且不是水的发泡剂。 因此,根据本发明的这些水解产物中加入额外的碱金属氢氧化物可用于中和酸性胶凝剂,从而提供增强化妆品和药物性能的凝胶。