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1. 发明授权

US4508912A Process for producing N-carbobenzoxy-L-aspartic anhydride 失效
标题翻译：制备N-苄氧羰基-L-天冬氨酸酐的方法
公开(公告)号：US4508912A
公开(公告)日：1985-04-02
申请号：US479898
申请日：1983-03-29
申请人： Tetsuo Yamatani , Toyoto Hijiya , Hideo Takeda , Koji Shibuya , Kiichiro Tanaka
发明人： Tetsuo Yamatani , Toyoto Hijiya , Hideo Takeda , Koji Shibuya , Kiichiro Tanaka
IPC分类号： C07D307/66
CPC分类号： C07D307/66
摘要： A process for producing a high yield of N-carbobenzoxy-L-aspartic anhydride from N-carbobenzoxy-L-aspartic acid in a very short period using commercially acceptable reaction conditions is disclosed. The process is characterized by reacting N-carbobenzoxy-L-aspartic acid with acetic anhydride in the presence of a metal oxide, a metal hydroxide, a metal salt of acid, an organobasic compound or an acid having a dissociation constant of 5.times.10.sup.-2 or more.
摘要翻译：公开了一种在非常短的时间内使用商业上可接受的反应条件从N-苄氧羰基-L-天冬氨酸生产N-苄氧羰基-L-天冬氨酸高产率的方法。该方法的特征在于N-烷氧羰基-L-天冬氨酸与乙酸酐在金属氧化物，金属氢氧化物，酸金属盐，有机碱化合物或解离常数为5×10 -2的酸的存在下反应，或更多。

2. 发明授权

US4536842A System for measuring interfloor traffic for group control of elevator cars 失效
标题翻译：用于电梯轿厢集团控制的车内交通流量测量系统
公开(公告)号：US4536842A
公开(公告)日：1985-08-20
申请号：US479899
申请日：1983-03-29
申请人： Kiyoshi Yoneda , Hiroshi Takeuchi , Tetsuo Yamatani , Toyoto Hijiya , Hideo Takeda , Koji Shibuya , Kiichiro Tanaka
发明人： Kiyoshi Yoneda , Hiroshi Takeuchi , Tetsuo Yamatani , Toyoto Hijiya , Hideo Takeda , Koji Shibuya , Kiichiro Tanaka
IPC分类号： B66B1/20 , B66B1/24 , G06F15/46 , B66B1/18
CPC分类号： B66B1/2458 , B66B2201/102 , B66B2201/214 , B66B2201/222 , B66B2201/235 , B66B2201/403
摘要： An elevator passenger traffic measuring system distributes passengers whose destination floors cannot be determined to each of origin-destination floor pairs in accordance with an elevator car position, an incoming passenger number and an outgoing passenger number at each floor, and registered car calls, using probability weights for the origin-destination floor pairs which are determined by previous traffic measurements. The system then estimates the number of passengers for each of the origin-destination floor pairs in accordance with the distributed passengers, and the passengers who moved the corresponding one of the origin-destination floor pairs.
摘要翻译：电梯客运测量系统根据电梯轿厢位置，每层楼的入场乘客人数和出行乘客人数以及使用概率的登记车辆呼叫来分配目的地楼层不能确定每个起点到目的地楼层对的乘客通过先前的流量测量确定的起始 - 目的地楼层对的权重。然后，该系统根据分配的乘客以及移动相应的一个起始 - 目的地楼层对的乘客来估计每个起始 - 目的地楼层对的乘客人数。

3. 发明授权

US5352450A Method for preparing vaccine for dental caries and vaccinal compositions for dental caries used as nasal drop 失效
标题翻译：用于龋齿疫苗的方法和用作鼻滴的龋齿的疫苗组合物
公开(公告)号：US5352450A
公开(公告)日：1994-10-04
申请号：US529602
申请日：1990-05-29
申请人： Toshihiko Koga , Nobuo Okahashi , Ichiro Takahashi , Koji Shibuya , Hirotaka Ohta
发明人： Toshihiko Koga , Nobuo Okahashi , Ichiro Takahashi , Koji Shibuya , Hirotaka Ohta
IPC分类号： A61K9/00 , A61K39/00 , C07K14/315 , A61K39/02 , C12P21/06 , C12P21/04
CPC分类号： A61K9/0043 , C07K14/315 , A61K39/00
摘要： A method for preparing a vaccine for dental caries comprises the step of culturing a variant which is obtained by integrating a protein antigen (PAc)-expressing gene into the chromosomal gene of a Streptococcus mutans GS-5 strain to obtain the protein antigen, the protein antigen being produced on the surface of cells of oral Streptococcus mutans or it being extracellularly produced by the microorganism and having a molecular weight ranging from about 170,000 to 220,000. Streptococcus mutans GS-5 (K-3), in which a protein antigen-expressing gene is integrated into the chromosomal gene thereof, has an ability of producing the protein antigen on the surface of the cells or extracellularly. A preventive vaccine composition for dental caries for nasal drops comprises the protein antigen thus produced by the strain: Streptcoccus mutans, the vaccine being intranasally administered. The method makes it possible to enhance the yield of PAc and to simplify processes for purifying PAc. The vaccine composition makes-it possible to internally easily absorb the protein antigen, PAc, in high efficiency and it also makes it possible to effectively increase the antibody titer observed after the administration thereof.
摘要翻译：制备龋齿疫苗的方法包括将通过将表达蛋白质抗原（PAc）的基因整合到变形链球菌GS-5株的染色体基因而获得的变体的方法来获得蛋白质抗原，所述蛋白质抗原在口腔变形链球菌的细胞表面产生，或由微生物细胞外产生，分子量范围为约17万至22万。其中将表达蛋白质抗原的基因整合到其染色体基因中的变形链球菌GS-5（K-3）具有在细胞表面或细胞外产生蛋白质抗原的能力。用于鼻滴龋齿的预防性疫苗组合物包含由菌株：由变形链球菌产生的蛋白质抗原，该疫苗被鼻内给药。该方法可以提高PAc的产率并简化PAc的纯化过程。疫苗组合物能够高效地内部容易地吸收蛋白质抗原PAc，并且还可以有效地增加施用后观察到的抗体滴度。

4. 发明授权

US5741487A Mutanase-containing oral compositions 失效
标题翻译：含有含Mutantase的口服组合物
公开(公告)号：US5741487A
公开(公告)日：1998-04-21
申请号：US806626
申请日：1997-02-26
申请人： Yoshio Asai , Motoyasu Ohdera , Hiromitsu Kigawa , Isao Shimotsuura , Yoshiko Yokobori , Masanori Hirano , Koji Shibuya
发明人： Yoshio Asai , Motoyasu Ohdera , Hiromitsu Kigawa , Isao Shimotsuura , Yoshiko Yokobori , Masanori Hirano , Koji Shibuya
IPC分类号： A61K8/00 , A61K8/66 , A61K38/46 , A61K38/47 , A61P1/02 , A61Q11/00 , A61Q11/02 , C12N1/20 , C12N9/24 , C12R1/07
CPC分类号： A61Q11/02 , A61K8/66 , A61Q11/00 , C12N9/2402 , C12Y302/01084
摘要： An oral composition contains mutanase prepared from a culture which is obtained by cultivating a mutanase-producing microorganism belonging to the genus Bacillus having negative protease producibility. The oral composition is effective for suppressing dental plaque formation while the mutanase possesses commercially acceptable stability in the oral composition.
摘要翻译：口服组合物含有由通过培养属于具有阴性蛋白酶生产能力的芽孢杆菌属的产生葡聚糖酶的微生物获得的培养物制备的齿斑葡聚糖酶。口腔组合物对于抑制牙菌斑形成是有效的，而斑驳葡聚糖酶在口腔组合物中具有商业上可接受的稳定性。

5. 发明授权

US5157987A Tie rod device 失效
标题翻译：拉杆装置
公开(公告)号：US5157987A
公开(公告)日：1992-10-27
申请号：US449241
申请日：1989-12-07
申请人： Shiro Satoh , Takashi Takeuchi , Koji Shibuya , Tetsuya Kogo
发明人： Shiro Satoh , Takashi Takeuchi , Koji Shibuya , Tetsuya Kogo
IPC分类号： B62D7/22 , G05G25/00
CPC分类号： G05G25/00 , B62D7/22 , Y10T74/2142 , Y10T74/2144 , Y10T74/2147
摘要： A tie rod device includes a vibration-absorbing damper. The tie rod comprises a tie rod assembly comprising first and second rods for interconnecting a rack shaft and a knuckle. The vibration-absorbing damper is interposed between the first and second rods for absorbing vibration transmitted from the knuckle.
摘要翻译：拉杆装置包括减振阻尼器。拉杆包括拉杆组件，其包括用于互连齿条轴和转向节的第一和第二杆。减震阻尼器介于第一和第二杆之间，用于吸收从转向节传递的振动。

6. 发明授权

US09294066B2 Transmission device 有权
标题翻译：传输设备
公开(公告)号：US09294066B2
公开(公告)日：2016-03-22
申请号：US14235964
申请日：2012-12-19
申请人： Koji Shibuya , Hideyuki Ohashi
发明人： Koji Shibuya , Hideyuki Ohashi
IPC分类号： H03H7/38 , H04B3/30 , H04L25/02
CPC分类号： H03H7/38 , H04B3/30 , H04L25/0272 , H04L25/0276 , H04L25/0278
摘要： A transmission device that establishes efficient match with an impedance mismatch section of a differential transmission system. The transmission device includes: a differential driver; a differential receiver; a differential line that connects between the differential driver and the differential receiver, the differential line including in-phase signal wiring and inverted-phase signal wiring; a delay increasing structure interposed in the differential line at an upstream of the impedance mismatch section; and a delay increasing structure interposed at a downstream of the impedance mismatch section. The delay increasing structure is interposed only in one of the in-phase signal wiring and the inverted-phase signal wiring, and the delay increasing structure is interposed only in another of the in-phase signal wiring and the inverted-phase signal wiring.
摘要翻译：一种与差分传输系统的阻抗失配部分建立有效匹配的传输装置。传动装置包括：差动驱动器; 差分接收机连接差分驱动器和差分接收器之间的差分线，差分线包括同相信号线和反相信号线; 在所述阻抗失配部分的上游插入所述差动线路中的延迟增加结构; 以及插入在阻抗失配部分的下游的延迟增加结构。延迟增加结构仅被插入到同相信号布线和反相信号布线中的一个中，并且延迟增加结构仅被插入在同相信号布线和反相信号布线中的另一个中。

7. 发明申请

US20140167875A1 TRANSMISSION DEVICE 有权
标题翻译：传输设备
公开(公告)号：US20140167875A1
公开(公告)日：2014-06-19
申请号：US14235964
申请日：2012-12-19
申请人： Koji Shibuya , Hideyuki Ohashi
发明人： Koji Shibuya , Hideyuki Ohashi
IPC分类号： H03H7/38
CPC分类号： H03H7/38 , H04B3/30 , H04L25/0272 , H04L25/0276 , H04L25/0278
摘要： A transmission device that establishes efficient match with an impedance mismatch section of a differential transmission system. The transmission device includes: a differential driver; a differential receiver; a differential line that connects between the differential driver and the differential receiver, the differential line including in-phase signal wiring and inverted-phase signal wiring; a delay increasing structure interposed in the differential line at an upstream of the impedance mismatch section; and a delay increasing structure interposed at a downstream of the impedance mismatch section. The delay increasing structure is interposed only in one of the in-phase signal wiring and the inverted-phase signal wiring, and the delay increasing structure is interposed only in another of the in-phase signal wiring and the inverted-phase signal wiring.
摘要翻译：一种与差分传输系统的阻抗失配部分建立有效匹配的传输装置。传动装置包括：差动驱动器; 差分接收机连接差分驱动器和差分接收器之间的差分线，差分线包括同相信号线和反相信号线; 在所述阻抗失配部分的上游插入所述差动线路中的延迟增加结构; 以及插入在阻抗失配部分的下游的延迟增加结构。延迟增加结构仅被插入到同相信号布线和反相信号布线中的一个中，并且延迟增加结构仅被插入在同相信号布线和反相信号布线中的另一个中。

8. 发明授权

US6164710A Dog waste receptacle and disposal device 失效
标题翻译：狗废物容器和处理装置
公开(公告)号：US6164710A
公开(公告)日：2000-12-26
申请号：US338792
申请日：1999-06-23
申请人： Koji Shibuya
发明人： Koji Shibuya
IPC分类号： A01K23/00 , A01K29/00
CPC分类号： A01K23/005
摘要： A dog waste receptacle device has a container with an opening at the top and bottom, a top cover and a bottom tray that each can be opened and closed freely, a latch for holding the bottom tray in a closed state, and a carrying rod whose lower end is attached to the side of the container. The top cover is hinged to the carrying rod in such a manner that it can be opened and closed freely. A trigger connected to the top cover for opening and closing it is mounted on the upper part of the carrying rod. A latching device capable of latching and unlatching the trigger is provided to hold the trigger in its position with the top cover open. A paper bag to accommodate dog droppings is placed inside the container. The top cover is closed under its own weight by releasing the trigger and the device is carried along by holding the carrying rod. As soon as the dog shows a motion of excreting, the top cover is opened and the container is placed under the dog's bottom. When returning from the walk, the bottom tray is released by pressing a knob with the tray positioned above a toilet, and the paper bag and its contents are readily disposed.
摘要翻译：狗废物容器装置具有在顶部和底部具有开口的容器，顶盖和底部托盘，每个容器可以自由地打开和关闭，用于将底部托盘保持在关闭状态的闩锁和承载杆，下端附着在容器的侧面。顶盖以可自由打开和关闭的方式铰接到承载杆上。连接到顶盖上用于打开和关闭触发器的触发器安装在承载杆的上部。提供能够锁定和解锁触发器的闩锁装置，以将触发器保持在顶盖打开的位置。容纳狗粪便的纸袋放置在容器内。顶盖通过释放扳机而在自重的情况下关闭，装置通过握住传送杆而携带。一旦狗显示出排泄物的动作，顶盖就被打开，容器被放在狗的底部。当从行走返回时，通过按压具有位于马桶上方的托盘的旋钮来释放底部托盘，并且容易地布置纸袋及其内容物。

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