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1. 发明申请

US20070265673A1 FLEXIBLE INTERCONNECT ASSEMBLY FOR IMPLANTABLE MEDICAL DEVICES 审中-公开
标题翻译：用于可植入医疗器械的柔性互连组件
公开(公告)号：US20070265673A1
公开(公告)日：2007-11-15
申请号：US11696142
申请日：2007-04-03
申请人： Terrance Ransbury , Stephen Purcell
发明人： Terrance Ransbury , Stephen Purcell
IPC分类号： A61N1/00
CPC分类号： A61N1/375 , Y10T29/49826
摘要： A modular implantable medical device having first and second component containers and a flexible connector for connecting the first and second containers. The connector can include a pair of end members and a flexible portion extending therebetween to define an internal passage between the end members. Each of the end members can include a receptacle configured to communicate with the containers. The connector further includes a conduit extending between the pair of end members in the internal passage to provide a communication path between the first and second containers such that the first and second component containers are in communication.
摘要翻译：具有第一和第二组件容器的模块化可植入医疗装置和用于连接第一和第二容器的柔性连接器。连接器可以包括一对端部构件和在它们之间延伸的柔性部分，以限定端部构件之间的内部通道。每个端部构件可以包括构造成与容器连通的插座。连接器还包括在内部通道中的一对端部构件之间延伸的导管，以在第一和第二容器之间提供连通路径，使得第一和第二组件容器连通。

2. 发明授权

US08204596B2 Isolation connector for an intravascular implantable medical device 有权
标题翻译：用于血管内植入式医疗设备的隔离连接器
公开(公告)号：US08204596B2
公开(公告)日：2012-06-19
申请号：US12263240
申请日：2008-10-31
申请人： Terrance Ransbury , Stephen Purcell
发明人： Terrance Ransbury , Stephen Purcell
IPC分类号： A61N1/00
CPC分类号： A61N1/375
摘要： Devices and methods providing for a isolation connector for a generally cylindrical or frustro-cylindrical housing of an implantable intravascular medical device are described herein. The isolation connector has a generally annular exterior surface, a proximal end, and a distal end. The isolation connector includes a housing interface portion at the proximal end which is secured to a first end of the housing. The proximal end of the housing interface portion is constructed to be obverse to the first end of the housing and presents a perimeter of substantially similar size and shape to the perimeter of the first end of the housing. The isolation connector further includes a first insulator portion disposed adjacent to a distal end of the housing interface portion. The isolation connector may further include a feed-through channel constructed to traverse the proximal and distal ends of the isolation connector and is defined through the housing interface portion and the first insulator portion. In an optional embodiment, an electrical conductor is disposed within the feed-through channel to electrically coupled at least one component disposed within the housing to at least one component disposed beyond the insulator portion.
摘要翻译：本文描述了提供用于可植入血管内医疗装置的大致圆柱形或截头圆柱形壳体的隔离连接器的装置和方法。隔离连接器具有大致环形的外表面，近端和远端。隔离连接器包括在近端处的壳体接口部分，其被固定到壳体的第一端。壳体接口部分的近端被构造成朝向壳体的第一端正面，并且具有与壳体的第一端的周边基本相似的尺寸和形状的周边。隔离连接器还包括邻近壳体接口部分的远端设置的第一绝缘体部分。隔离连接器还可以包括构造成穿过隔离连接器的近端和远端并且通过壳体接口部分和第一绝缘体部分限定的馈通通道。在可选实施例中，电导体设置在馈通通道内，以将布置在壳体内的至少一个部件电耦合到设置在绝缘体部分之外的至少一个部件。

3. 发明授权

US07899554B2 Intravascular System and Method 有权
标题翻译：血管内系统和方法
公开(公告)号：US07899554B2
公开(公告)日：2011-03-01
申请号：US11980006
申请日：2007-10-30
申请人： Michael S. Williams , Terrance Ransbury , Richard A. Glenn , Daniel W. Fifer , Kevin Holbrook
发明人： Michael S. Williams , Terrance Ransbury , Richard A. Glenn , Daniel W. Fifer , Kevin Holbrook
IPC分类号： A61N1/02
CPC分类号： A61N1/057 , A61N1/37205 , A61N1/375
摘要： The present application describes an intravascular implantable pacing and/or defibrillation system. The described system includes a pulse generator that is implantable within a blood vessel and proportioned to blood flow through the blood vessel, and at least one electrode attachable to the pulse generator. During implantation, the pulse generator is introduced into a patient's vasculature, advanced to a desired vessel and anchored in place within the vessel. The electrode or electrodes are placed within the heart or surrounding vessels as needed to deliver electrical pulses to the appropriate location.
摘要翻译：本申请描述了血管内可植入起搏和/或除颤系统。所描述的系统包括脉冲发生器，该脉冲发生器可植入血管内并与通过血管的血液流动成比例，以及至少一个可附着到脉冲发生器的电极。在植入期间，将脉冲发生器引入患者的脉管系统中，前进到期望的血管并锚定在血管内的适当位置。根据需要将电极或电极放置在心脏或周围血管内，以将电脉冲传递到适当的位置。

4. 发明申请

US20090281521A1 METHOD AND APPARATUS FOR RETAINING MEDICAL IMPLANTS WITHIN BODY VESSELS 失效
标题翻译：用于在体内保留医用植入物的方法和装置
公开(公告)号：US20090281521A1
公开(公告)日：2009-11-12
申请号：US12506232
申请日：2009-07-20
申请人： Michael S. Williams , Terrance Ransbury , Richard A. Glenn , Kevin Holbrook
发明人： Michael S. Williams , Terrance Ransbury , Richard A. Glenn , Kevin Holbrook
IPC分类号： A61M31/00 , A61N1/05
CPC分类号： A61N1/057 , A61N1/37205 , A61N1/375
摘要： The present application describes a retention device for anchoring a medical device within the vasculature. The device may include expandable member coupled to an intravascular medical device and proportioned for receipt within a vessel. At least a portion of the expandable member is expandable to radially engage a vessel wall and to thereby retain the medical device within the vessel. The system is suitable for a variety of intravascular devices, including but not limited to ICD's, pacemakers, and intravascular drug delivery systems.
摘要翻译：本申请描述了用于将医疗装置锚定在脉管系统内的保持装置。该装置可以包括联接到血管内医疗装置并且成比例地用于在容器内接收的可扩张构件。可膨胀构件的至少一部分可扩张以径向接合容器壁并由此将医疗装置保持在容器内。该系统适用于各种血管内装置，包括但不限于ICD，起搏器和血管内药物输送系统。

5. 发明申请

US20090192579A1 IMPLANTATION METHODS, SYSTEMS AND TOOLS FOR INTRAVASCULAR IMPLANTABLE DEVICES 审中-公开
标题翻译：静脉注射装置的植入方法，系统和工具
公开(公告)号：US20090192579A1
公开(公告)日：2009-07-30
申请号：US12327808
申请日：2008-12-03
申请人： Terrance Ransbury , Kevin Holbrook
发明人： Terrance Ransbury , Kevin Holbrook
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61B17/064 , A61B17/068 , A61B2017/0649 , A61M39/0613 , A61N1/0573 , A61N2001/0578
摘要： Methods, systems and tools for implanting long-term active therapeutic medical devices referred to as intravascular implantable devices (IID) within a patient's vasculature are disclosed. In one embodiment, the implantation techniques and instruments of the present invention are adapted for implanting an IID having only a single anchoring arrangement positioned proximate a distal portion of the device for anchoring within a vessel located superior to the heart, i.e. above the heart in a direction toward the head of a patient. Other embodiments of the invention include various methods and tools for delivering and implanting an IID, delivering and securing an anchor, and delivering and implanting one or more leads.
摘要翻译：公开了用于植入长期活跃治疗医疗装置的方法，系统和工具，称为患者脉管系统内的血管内可植入装置（IID）。在一个实施例中，本发明的植入技术和仪器适于植入仅具有靠近装置的远端部分定位的单个锚固装置的IID，用于锚定在位于心脏上方的容器内，即位于心脏上方的血管朝向患者头部的方向。本发明的其它实施例包括用于递送和植入IID，递送和固定锚定器以及递送和植入一个或多个引线的各种方法和工具。

6. 发明申请

US20080147168A1 Intravascular implantable device having detachable tether arrangement 审中-公开
标题翻译：具有可拆卸系绳布置的血管内植入装置
公开(公告)号：US20080147168A1
公开(公告)日：2008-06-19
申请号：US11999517
申请日：2007-12-04
申请人： Terrance Ransbury , Kevin Holbrook
发明人： Terrance Ransbury , Kevin Holbrook
IPC分类号： A61F2/06
CPC分类号： A61N1/375 , A61F2/82 , A61N1/056 , A61N1/0563
摘要： An intravascular implantable medical device includes a detachable tether arrangement. In one embodiment, the detachable tether arrangement comprises a tip assembly that includes a break-away joint and a tether portion, and may also include a connector and an extension portion connected to an end of an elongated intravascular implantable medical device. In this embodiment, the break-away joint is disposed between the extension portion and the tether portion. In some embodiments, the extension portion may comprise a housing or other arrangement that includes an antenna for transmitting and receiving data. In other embodiments, the extension portion may also include a lead for defibrillation, pacing, and/or sensing cardiac electrical activity. In certain embodiments, the tether arrangement is designed to be secured within a patient's vasculature with a vascular anchor either in the form of a separate anchor, such as a conventional stent, or by various integrated retention arrangements.
摘要翻译：血管内可植入医疗装置包括可拆卸系绳装置。在一个实施例中，可拆卸的系链装置包括尖端组件，其包括分离接头和系绳部分，并且还可以包括连接器和连接到细长的血管内可植入医疗装置的端部的延伸部分。在该实施例中，脱开接头设置在延伸部和系链部之间。在一些实施例中，延伸部分可以包括外壳或其他布置，其包括用于发送和接收数据的天线。在其他实施例中，延伸部分还可以包括用于除颤，起搏和/或感测心脏电活动的引线。在某些实施例中，系链装置被设计成用血管锚定件固定在病人的脉管系统中，或者以单独的锚，例如常规支架的形式，或通过各种整合的保留装置。

7. 发明申请

US20130072997A1 SYSTEM AND METHOD FOR NEUROMODULATION 有权
标题翻译：神经修复的系统和方法
公开(公告)号：US20130072997A1
公开(公告)日：2013-03-21
申请号：US13547031
申请日：2012-07-11
申请人： William E. Sanders , Stephen C. Masson , Terrance Ransbury , Richard S. Stack
发明人： William E. Sanders , Stephen C. Masson , Terrance Ransbury , Richard S. Stack
IPC分类号： A61N1/36
CPC分类号： A61N1/36114 , A61N1/0551 , A61N1/056 , A61N1/36053 , A61N1/36135 , A61N1/36139
摘要： A method of treating autonomic imbalance in a patient includes energizing a first therapeutic element disposed in a superior vena cava of the patient to deliver therapy to a parasympathetic nerve fiber (e.g. vagus nerve), and energizing a second therapeutic element disposed within the superior vena cava to deliver therapy to a sympathetic cardiac nerve fiber. A neuromodulation system includes a parasympathetic therapy element adapted for positioning within a blood vessel, a sympathetic therapy element adapted for positioning within the blood vessel; and a stimulator to energize the parasympathetic therapy element to deliver parasympathetic therapy to a parasympathetic nerve fiber disposed external to the blood vessel and energize the sympathetic therapy element within the blood vessel to deliver sympathetic therapy to a sympathetic nerve fiber disposed external to the blood vessel. The therapy decreases the patient's heart rate and elevates or maintains the blood pressure of the patient.
摘要翻译：一种治疗患者自主性不平衡的方法包括激励设置在患者上腔静脉中的第一治疗元件，以将治疗递送至副交感神经纤维（例如迷走神经），以及激励位于上腔静脉内的第二治疗元件为交感神经纤维提供治疗。神经调节系统包括适于定位在血管内的副交感神经治疗元件，适于定位在血管内的交感治疗元件; 以及刺激器，用于激励所述副交感神经治疗元件以将副交感神经治疗递送到设置在所述血管外部的副交感神经纤维，并激励所述血管内的所述交感神经治疗元件，以将交感神经治疗递送至设置在所述血管外部的交感神经纤维。该疗法可降低患者的心率，提高或维持患者的血压。

8. 发明授权

US08239045B2 Device and method for retaining a medical device within a vessel 有权
标题翻译：用于将医疗装置保持在容器内的装置和方法
公开(公告)号：US08239045B2
公开(公告)日：2012-08-07
申请号：US10453971
申请日：2003-06-04
申请人： Terrance Ransbury , Michael S. Williams
发明人： Terrance Ransbury , Michael S. Williams
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/056 , A61N1/057 , A61N1/37205
摘要： A method and apparatus for retaining a medical device within a blood vessel are described. A medical device (e.g. a pulse generator or a lead) is positioned within a blood vessel. An expandable the retention sleeve is passed into the vessel adjacent to the medical device and expanded to an expanded position to engage the medical device between an exterior surface of the retention sleeve and a surface of the vessel.
摘要翻译：描述了用于将医疗装置保持在血管内的方法和装置。医疗装置（例如脉冲发生器或引线）位于血管内。将可扩张的保持套筒传送到与医疗装置相邻的容器中并且膨胀到扩张位置，以在保持套筒的外表面和容器的表面之间接合医疗装置。

9. 发明申请

US20090163927A1 DELIVERY TOOLS AND METHODS FOR INTRAVASCULAR IMPLANTABLE DEVICES 审中-公开
标题翻译：递送工具和方法用于静脉内植入装置
公开(公告)号：US20090163927A1
公开(公告)日：2009-06-25
申请号：US12327785
申请日：2008-12-03
申请人： Terrance Ransbury , Kevin Holbrook
发明人： Terrance Ransbury , Kevin Holbrook
IPC分类号： A61B17/00 , A61N1/02
CPC分类号： A61N1/056 , A61B17/064 , A61B17/068 , A61B2017/0649 , A61M39/0613 , A61N1/0573 , A61N2001/0578
摘要： Improved methods and apparatuses for positioning intravascular implantable device (IID) in a patient's vasculature utilize a device delivery system having an elongated flexible body. A handle can be operably connected to the proximal end and a grasper mechanism can be positioned at the distal end of the device delivery system. The grasper mechanism can be configured to releasably grasp the IID by closing a releasable honda around the IID and can be selectively controllable with the handle.
摘要翻译：用于在患者的脉管系统中定位血管内可植入装置（IID）的改进的方法和装置利用具有细长的柔性体的装置递送系统。手柄可以可操作地连接到近端，并且抓紧机构可以定位在装置输送系统的远端。抓紧机构可以构造成通过闭合IID周围的可释放本体来可释放地抓住IID，并且可以用手柄选择性地控制。

10. 发明申请

US20090118798A1 ISOLATATION CONNECTOR FOR AN INTRAVASCULAR IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：静脉插入式医疗装置隔离连接器
公开(公告)号：US20090118798A1
公开(公告)日：2009-05-07
申请号：US12263240
申请日：2008-10-31
申请人： Terrance Ransbury
发明人： Terrance Ransbury
IPC分类号： A61N1/375 , H01R4/60 , H01R4/50
CPC分类号： A61N1/375
摘要： Devices and methods providing for a isolation connector for a generally cylindrical or frustro-cylindrical housing of an implantable intravascular medical device are described herein. The isolation connector has a generally annular exterior surface, a proximal end, and a distal end. The isolation connector includes a housing interface portion at the proximal end which is secured to a first end of the housing. The proximal end of the housing interface portion is constructed to be obverse to the first end of the housing and presents a perimeter of substantially similar size and shape to the perimeter of the first end of the housing. The isolation connector further includes a first insulator portion disposed adjacent to a distal end of the housing interface portion. The isolation connector may further include a feed-through channel constructed to traverse the proximal and distal ends of the isolation connector and is defined through the housing interface portion and the first insulator portion. In an optional embodiment, an electrical conductor is disposed within the feed-through channel to electrically coupled at least one component disposed within the housing to at least one component disposed beyond the insulator portion.
摘要翻译：本文描述了提供用于可植入血管内医疗装置的大致圆柱形或截头圆柱形壳体的隔离连接器的装置和方法。隔离连接器具有大致环形的外表面，近端和远端。隔离连接器包括在近端处的壳体接口部分，其被固定到壳体的第一端。壳体接口部分的近端被构造成朝向壳体的第一端正面，并且具有与壳体的第一端的周边基本相似的尺寸和形状的周边。隔离连接器还包括邻近壳体接口部分的远端设置的第一绝缘体部分。隔离连接器还可以包括构造成穿过隔离连接器的近端和远端并且通过壳体接口部分和第一绝缘体部分限定的馈通通道。在可选实施例中，电导体设置在馈通通道内，以将布置在壳体内的至少一个部件电耦合到设置在绝缘体部分之外的至少一个部件。

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