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1. 发明申请

US20070134389A1 Unsaturated cyclic and acyclic carbamates exhibiting taste and flavor enhancement effect in flavor compositions 有权
标题翻译：不饱和的环状和非环状的氨基甲酸酯在风味组合物中表现出味道和风味增强效果
公开(公告)号：US20070134389A1
公开(公告)日：2007-06-14
申请号：US11304151
申请日：2005-12-14
申请人： Tao Pei , Mark Dewis , Adam Janczuk
发明人： Tao Pei , Mark Dewis , Adam Janczuk
IPC分类号： A23L1/236
CPC分类号： C07C333/04 , A23L27/20 , C07C271/12 , C07C271/34 , C07C271/44 , C07C317/18 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07D333/48
摘要： The present invention relates to novel compounds having sweet, salt or umami taste enhancement qualities. These compounds have the structure: where R1 is H or methyl; R2 is selected from the group consisting of H, C1-C4 alkyl, alkenyl; R3 is selected from the group consisting of H, phenyl, C1-C10 straight or branched chain alkyl, alkenyl, alkynyl, alkyldienyl, acyclic or containing no more than one ring, which contains no more than a total of five heteroatoms selected from F, O, S, N, and P; and if R1=H, R2 and R3 taken together can represent cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl, which contains no more than two of each heteroatom selected from N, O, and S; or if R1, R2 and R3 taken together can represent one, or two aromatic rings, which contain no more than three of each heteroatom selected from F, N, S, and O. R4 is selected from the group consisting of H, methyl or ethyl; R5 is selected from the group consisting of H, methyl and ethyl; R6 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring; except for in the case of structure 1 when if R4=H or methyl and R5=H or methyl, R6 as described above and phenyl; or when R4, R5, and R6 taken together can be equal to R7 is selected from the group consisting C1-C4 alkyl, or alkenyl.
摘要翻译：本发明涉及具有甜味，盐或鲜味增强品质的新颖化合物。这些化合物具有以下结构：其中R 1是H或甲基; R 2选自H，C 1 -C 4烷基，烯基; R 3选自H，苯基，C 1 -C 10直链或支链烷基，烯基，炔基，烷基二烯基，无环或不超过一个环，其不超过一个共有五个选自F，O，S，N和P的杂原子; 并且如果R 1 = H，R 2和R 3一起可以表示环丙基，环丁基，环戊基，环戊烯基，环己基或环己烯基，其含有不多于两个选自N，O和S的杂原子; 或者如果R 1，R 2和R 3一起可以代表一个或两个芳环，其包含不超过三个的每个选自F，N，S和O的杂原子。R 4选自H，甲基或乙基; R 5选自H，甲基和乙基; R 6选自H，C 1 -C 9直链或支链烷基，烯基，烷基二烯基，无环或不超过一个环; 除了在结构1的情况下，如果R 4 = H或甲基，R 5 = H或甲基，则如上所述，R 6 和苯基; 或当R 4，R 5，R 6和R 6合在一起可以等于R 7选自该基团由C 1 -C 4烷基或烯基组成。

2. 发明申请

US20060068071A1 Saturated and unsaturated N-alkamides exhibiting taste and flavor enhancement effect in flavor compositions 有权
公开(公告)号：US20060068071A1
公开(公告)日：2006-03-30
申请号：US11178179
申请日：2005-07-08
申请人： Mark Dewis , Garry Conkiln , Tao Pei , Catherine Smith , Adam Janczuk
发明人： Mark Dewis , Garry Conkiln , Tao Pei , Catherine Smith , Adam Janczuk
IPC分类号： A23L1/22
CPC分类号： C07C233/05 , A23L2/56 , A23L23/00 , A23L27/2054 , A23L27/40 , A23L27/88 , A61K47/18 , C07C233/09 , C07C233/58 , C07C2602/02
摘要： The present invention is directed to novel compounds and a process for augmenting or imparting a flavor enhancement effect or modifying the perception of one or more of the five basic taste qualities sweet, sour, salt, bitter and umami, to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup a flavor enhancement or modification of basic taste quality augmenting, enhancing or imparting quantity and concentration of at least one N-substituted unsaturated alkyl amide defined according to the structures:

3. 发明申请

US20060057268A1 Saturated and unsaturated N-alkamides exhibiting taste and flavor enhancement effect in flavor compositions 有权
标题翻译：饱和和不饱和的N-烷酰胺在风味组合物中表现出味道和风味增强效果
公开(公告)号：US20060057268A1
公开(公告)日：2006-03-16
申请号：US10939096
申请日：2004-09-10
申请人： Mark Dewis , Garry Conklin , Tao Pei
发明人： Mark Dewis , Garry Conklin , Tao Pei
IPC分类号： A23L1/22
CPC分类号： C07C233/05 , A23L27/202 , A23L27/203 , A23L27/204
摘要： Saturated and unsaturated compounds having sweet, salt or umami taste enhancement qualities. The compounds have the structure: where R1═H or methyl; R2 is selected from the group consisting of H, C1-C4 alkyl, alkenyl and methylene; R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl or phenyl; or if R1═H, R2 and R3 taken together can represent cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl; R4 is selected from the group consisting of H, methyl and ethyl; R5 is selected from the group consisting of H, methyl and ethyl; R6 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring; with the proviso that in structure 1 when R4 is H or Me; and R5═H or methyl, R6 may be selected from the group described above or phenyl.
摘要翻译：饱和和不饱和化合物，具有甜味，盐或鲜味增强品质。该化合物具有以下结构：

4. 发明申请

US20050075368A1 Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof 有权
公开(公告)号：US20050075368A1
公开(公告)日：2005-04-07
申请号：US10919631
申请日：2004-08-17
申请人： Mark Dewis , Thumplasseril John , Markus Eckert , Jan Colstee , Neil Da Costa , Tao Pei
发明人： Mark Dewis , Thumplasseril John , Markus Eckert , Jan Colstee , Neil Da Costa , Tao Pei
IPC分类号： A01N25/00 , A01N37/18 , A01N65/00 , A23G3/34 , A23G4/00 , A23G4/06 , A23L1/222 , A23L1/226 , A23L1/305 , A23L2/56 , A61K8/42 , A61K47/16 , A61K47/22 , A61Q11/00 , C07C233/09 , C07C235/76 , C07D207/08 , C07D211/30 , C07D211/32 , C07D295/185 , C11B9/00 , A61K31/445 , A61K31/16 , A61K31/401
CPC分类号： A23G3/346 , A01N37/18 , A01N65/08 , A23G4/06 , A23G4/068 , A23G2200/00 , A23G2200/14 , A23L2/56 , A23L27/2028 , A23L27/2054 , A23L33/175 , A61K8/42 , A61Q5/02 , A61Q11/00 , A61Q13/00 , A61Q17/005 , C07C233/09 , C07D295/185 , C11B9/0019 , C11B9/0092 , A01N2300/00
摘要： Described are mixtures of at least four of the alkadienamides defined according to the structure: wherein R represents C1-C2 n-alkyl; R1 is 2-methyl-1-propyl and R2 is hydrogen, or R1 and R2 taken together is a moiety having the formula —(CH2)n— wherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.

5. 发明申请

US20050042257A1 Ethyl 3-mercaptobutyrate as a flavoring or fragrance agent and methods for preparing and using same 审中-公开
标题翻译： 3-巯基丁酸乙酯作为调味剂或香料，以及制备和使用它们的方法
公开(公告)号：US20050042257A1
公开(公告)日：2005-02-24
申请号：US10955833
申请日：2004-09-30
申请人： Mark Dewis , David Edwards , Lesley Kendrick , Maria Wright , Amir Yusuf
发明人： Mark Dewis , David Edwards , Lesley Kendrick , Maria Wright , Amir Yusuf
IPC分类号： A23L27/00 , A23L27/20 , A23L27/29 , A61K47/00 , A23L2/00
CPC分类号： A23G3/36 , A23G3/48 , A23G4/06 , A23G4/068 , A23L27/2022 , A23L27/29 , C11B9/0011
摘要： This invention pertains to a method for flavoring an ingestible composition with a flavoring agent in organoleptically purified form, unaccompanied by substances of natural origin present in mango. The flavoring agent may be used in a wide variety of ingestible vehicles such as chewing gum compositions, hard and soft confections, dairy products, beverage products including juice drinks and juice products, green vegetable and chicken products, and the like. The present invention also pertains to an ingestible composition comprising an ingestible vehicle and an organoleptically effective amount of the purified flavoring agent. The present invention further pertains to ethyl 3-mercaptobutyrate represented by the formula, CH3(SH)CHCH2COOCH2CH3, in purified form, unaccompanied by substances of natural origin present in mango. The present invention still further pertains to a method to confer, enhance, improve, or modify the odor properties of a perfuming composition or a perfumed article, which comprises adding to the perfuming composition or perfumed article, ethyl 3-mercaptobutyrate represented by the formula, CH3(SH)CHCH2COOCH2CH3. The present invention still further pertains to a perfuming composition or a perfumed article containing as an active perfuming ingredient, ethyl 3-mercaptobutyrate represented by the formula, CH3(SH)CHCH2COOCH2CH3. The present invention also pertains to a method for preparing ethyl 3-mercaptobutyrate which comprises reacting ethyl crotonate with sodium hydrogen sulfide and sodium bicarbonate to form the disulfide dimer of ethyl 3-mercaptobutyrate followed by reducing the disulfide dimer to yield ethyl 3-mercaptobutyrate.
摘要翻译：本发明涉及一种通过感官纯化形式调味具有调味剂的可摄入组合物的方法，不伴随芒果中存在的天然来源的物质。调味剂可以用于各种可摄取的载体，例如口香糖组合物，硬和软糖果，乳制品，饮料产品，包括果汁饮料和果汁产品，绿色蔬菜和鸡肉制品等。本发明还涉及包含可摄入载体和感官有效量的纯化调味剂的可摄取组合物。本发明还涉及以通式CH3（SH）CHCH2COOCH2CH3表示的3-巯基丁酸乙酯，纯化形式，不含芒果中存在的天然来源的物质。本发明还涉及赋予，增强，改善或改善加香组合物或加香制品的气味性质的方法，其包括向加香组合物或香料制品中加入由式表示的3-巯基丁酸乙酯， CH3（SH）CHCH2COOCH2CH3。本发明还涉及含有作为活性加香成分的由式CH3（SH）CHCH2COOCH2CH3表示的3-巯基丁酸乙酯的加香组合物或香料制品。本发明还涉及制备3-巯基丁酸乙酯的方法，该方法包括使巴豆酸乙酯与硫化氢钠和碳酸氢钠反应，形成3-巯基丁酸乙酯的二硫化物二聚物，然后还原二硫化物二聚物，得到3-巯基丁酸乙酯。

6. 发明申请

US20070225199A1 FRUIT, BERRY, CRANBERRY AND HEDONICALLY-STABLE CITRUS FLAVORED COMPOSITIONS AND PROCESS FOR PREPARING SAME 有权
标题翻译：水果，白葡萄酒，克兰巴兰和HEDONICALLY-STABLE CITRUS FLAVORED COMPOSITIONS AND PROCESS FOR PREPARTING SAME
公开(公告)号：US20070225199A1
公开(公告)日：2007-09-27
申请号：US11419311
申请日：2006-06-16
申请人： Mark Dewis , Michelle Huber , David Agyemang , Garry Conklin
发明人： Mark Dewis , Michelle Huber , David Agyemang , Garry Conklin
IPC分类号： A61Q13/00
CPC分类号： A23L2/56 , A23L27/2026 , A23L27/203 , A23L27/29
摘要： Described is to a process for augmenting, enhancing, modifying or imparting a berry or citrus aroma or taste in or to a foodstuff or aqueous beverage comprising the step of adding to a foodstuff or aqueous beverage an aroma or taste augmenting, enhancing, modifying or imparting quantity and concentration of at least one oxo-terpene carbinol, carbinyl C1-C6 alkanoate or C4-C6 alkenoate.
摘要翻译：描述了一种用于在食品或含水饮料中增加，增强，改良或赋予浆果或柑橘香气或味道的方法，其包括向食品或水性饮料中添加芳香或味道增强，增强，改性或赋予至少一种氧代 - 萜烯甲醇的量和浓度，碳水化合物C 1 -C 6烷酸酯或C 4 -C 6烷基， /亚油酸酯。

7. 发明申请

US20050074533A1 Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof 有权
标题翻译：共轭二烯酰胺，其制备方法，含有它们的组合物及其用途
公开(公告)号：US20050074533A1
公开(公告)日：2005-04-07
申请号：US10678558
申请日：2003-10-03
申请人： Thumplasseril John , Markus Eckert , Mark Dewis , Jan Colstee , Neil da Costa
发明人： Thumplasseril John , Markus Eckert , Mark Dewis , Jan Colstee , Neil da Costa
IPC分类号： A23G3/34 , A23G4/00 , A23G4/06 , A23L1/226 , A23L1/305 , A23L2/56 , A61K8/42 , A61Q11/00 , C07C233/09 , C07D295/185 , A23L1/22
CPC分类号： C07D295/185 , A01N65/08 , A23G3/346 , A23G4/06 , A23G4/068 , A23G2200/00 , A23G2200/14 , A23L2/56 , A23L3/3472 , A23L27/11 , A23L27/12 , A23L27/2028 , A23L27/2054 , A23L33/105 , A23L33/12 , A23L33/175 , A61K8/42 , A61K8/4913 , A61K8/4926 , A61K2800/242 , A61Q5/02 , A61Q11/00 , A61Q13/00 , A61Q17/005 , A61Q19/00 , C07C233/09
摘要： Described are mixtures of at least four of the alkadienamides defined according to the structure: wherein R represents C1-C2 n-alkyl; R1 is 2-methyl-1-propyl and R2 is hydrogen, or R1 and R2 taken together is a moiety having the formula —(CH2)n— wherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.
摘要翻译：描述了根据以下结构定义的至少四种烷酰胺的混合物：其中R表示C 1 -C 2正烷基; R 1是2-甲基-1-丙基，R 2是氢，或者R 1和R 2一起是具有式 - （CH 2）n - 的部分，其中n是4或5，或包含基本浓度的这种混合物的组合物，以新颖的方法：（a）提取一种Pi子种，Pi um n或琵琶鹦鹉之一的基本干燥的果实; （b）天然产物形成合成; 或（c）合成产物形成合成。还描述了如此形成的产品用于在消耗材料和/或口腔和/或哺乳动物表皮中或/或在哺乳动物表皮上增加，增强或赋予芳香，味觉，化学疗效和/或抗菌作用的用途。

8. 发明申请

US20050010062A1 E2,E4,Z8-UNDECATRIENOIC ACID AND ESTER AND CARBOXAMIDE DERIVATIVES THEREOF, ORGANOLEPTIC USES THEREOF AND PROCESSES FOR PREPARING SAME 有权
标题翻译： E2，E4，Z8-非氨基酸和酯及其羧酰胺衍生物，其有机物用途及其制备方法
公开(公告)号：US20050010062A1
公开(公告)日：2005-01-13
申请号：US10618367
申请日：2003-07-10
申请人： Mark Dewis , Michelle Huber
发明人： Mark Dewis , Michelle Huber
IPC分类号： A23L1/226 , A61K8/36 , A61K8/37 , A61K8/42 , A61K8/49 , A61Q5/12 , A61Q11/00 , A61Q19/00 , C07C51/16 , C07C51/295 , C07C57/03 , C07C67/12 , C07C69/587 , C07C69/96 , C07C233/09 , C07C233/02 , C07D317/44
CPC分类号： A61K8/361 , A23L27/2026 , A23L27/2054 , A61K8/37 , A61K8/42 , A61K8/4973 , A61Q5/12 , A61Q11/00 , A61Q19/00 , C07C51/16 , C07C51/295 , C07C57/03 , C07C67/12 , C07C69/587 , C07C69/96 , C07C233/09
摘要： Described is a genus of E2,E4,Z8-undecatrienoic acid derivatives defined according to the structure: wherein Z represents —OR″ or —NRR′ with the provisos that when Z is —OR″, R″ is hydrogen, C1-C6 straight chain or branched-chain alkyl or C3-C6 straight chain or branched-chain alkenyl; and when Z is —NRR′, R represents, in the alternative, hydrogen, methyl or ethyl and R′ represents methyl, ethyl, n-propyl, cyclopropyl, isopropyl, n-butyl, sec-butyl, isobutyl, 2-methylbutyl, cyclobutyl, cyclopentyl or allyl. The E2,E4,Z8-undecatrienoic acid derivatives are useful in imparting, augmenting and/or enhancing flavors, aromas and somatosensory effects in or to consumable materials such as foods, beverages, skin care products, oral care products, medicinal products and the like. Also described is a synthesis process for producing such derivatives.
摘要翻译：描述了根据以下结构定义的E2，E4，Z8-十一碳烯酸衍生物属：其中Z表示-OR“或-NRR'，条件是当Z为-OR”时，R“为氢，C1 -C6直链或支链烷基或C3-C6直链或支链烯基; 当Z是-NRR'时，R代表氢，甲基或乙基，R'代表甲基，乙基，正丙基，环丙基，异丙基，正丁基，仲丁基，异丁基，2-甲基丁基，环丁基，环戊基或烯丙基。 E2，E4，Z8-十一碳三烯酸衍生物可用于赋予，增强和/或增强食用，饮料，护肤品，口腔护理产品，药用产品等中的消耗材料中的香料，香气和体感效应。还描述了制备这种衍生物的合成方法。

9. 发明申请

US20080008811A1 CONJUGATED DIENAMIDES, METHODS OF PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAME AND USES THEREOF 有权
标题翻译：连结剂，其生产方法，包含其的组合物及其用途
公开(公告)号：US20080008811A1
公开(公告)日：2008-01-10
申请号：US11857672
申请日：2007-09-19
申请人： Thumplasseril John , Markus Eckert , Mark Dewis , Jan Colstee , Neil da Costa
发明人： Thumplasseril John , Markus Eckert , Mark Dewis , Jan Colstee , Neil da Costa
IPC分类号： A23L1/221
CPC分类号： C07D295/185 , A01N65/08 , A23G3/346 , A23G4/06 , A23G4/068 , A23G2200/00 , A23G2200/14 , A23L2/56 , A23L3/3472 , A23L27/11 , A23L27/12 , A23L27/2028 , A23L27/2054 , A23L33/105 , A23L33/12 , A23L33/175 , A61K8/42 , A61K8/4913 , A61K8/4926 , A61K2800/242 , A61Q5/02 , A61Q11/00 , A61Q13/00 , A61Q17/005 , A61Q19/00 , C07C233/09
摘要： Described are mixtures of at least four of the alkadienamides defined according to the structure: wherein R represents C1-C2 n-alkyl; R1 is 2-methyl-1-propyl and R2 is hydrogen, or R1 and R2 taken together is a moiety having the formula —(CH2)n—, wherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.
摘要翻译：描述了根据以下结构定义的至少四种烷酰胺的混合物：其中R表示C 1 -C 2烷基; R 1是2-甲基-1-丙基，R 2是氢，或R 1和R 2是氢，一起是具有下式的部分：其中n为4或5，或含有基本浓度的这种混合物的组合物，其按照新颖的方法制备过程：（a）提取per皮种之一的干燥果实，Pi um或per per; （b）天然产物形成合成; 或（c）合成产物形成合成。还描述了如此形成的产品用于在消耗材料和/或口腔和/或哺乳动物表皮中或/或在哺乳动物表皮上增强，增强或赋予芳香，味觉，化学疗效和/或抗菌作用的用途。

10. 发明申请

US20080008810A1 CONJUGATED DIENAMIDES, METHODS OF PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAME AND USES THEREOF 有权
公开(公告)号：US20080008810A1
公开(公告)日：2008-01-10
申请号：US11857587
申请日：2007-09-19
申请人： Thumplasseril John , Markus Eckert , Mark Dewis , Jan Colstee , Neil Costa
发明人： Thumplasseril John , Markus Eckert , Mark Dewis , Jan Colstee , Neil Costa
IPC分类号： A23L1/221
CPC分类号： C07D295/185 , A01N65/08 , A23G3/346 , A23G4/06 , A23G4/068 , A23G2200/00 , A23G2200/14 , A23L2/56 , A23L3/3472 , A23L27/11 , A23L27/12 , A23L27/2028 , A23L27/2054 , A23L33/105 , A23L33/12 , A23L33/175 , A61K8/42 , A61K8/4913 , A61K8/4926 , A61K2800/242 , A61Q5/02 , A61Q11/00 , A61Q13/00 , A61Q17/005 , A61Q19/00 , C07C233/09
摘要： Described are mixtures of at least four of the alkadienamides defined according to the structure: wherein R represents C1-C2 n-alkyl; R1 is 2-methyl-1-propyl and R2 is hydrogen, or R1 and R2 taken together is a moiety having the formula —(CH2)n—, wherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.

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