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1. 发明申请

US20050089921A1 Methods and compositions for destabilizing microtubules 失效
标题翻译：不稳定微管的方法和组合物
公开(公告)号：US20050089921A1
公开(公告)日：2005-04-28
申请号：US11003543
申请日：2004-12-03
申请人： Tang Tang , Liang-Yi Hung , Ching-Wen Chang
发明人： Tang Tang , Liang-Yi Hung , Ching-Wen Chang
IPC分类号： A61K38/00 , C07K14/47 , C12Q1/68 , C07H21/04 , C12N9/22 , C12N15/85
CPC分类号： C07K14/47 , A61K38/00
摘要： Polypeptides that comprise an approximately 100-amino acid residue region of a centrosomal P4.1-associated protein (CPAP) that possess microtubule-destabilizing activity, polynucleotides encoding such polypeptides, compositions comprising the polypeptides and polynucleotides, and methods of use thereof, are disclosed. The invention is useful for destabilizing microtubules in eukaryotic cells, including but not limited to cancer cells.
摘要翻译：公开了包含具有微管去稳定活性的中心体P4.1相关蛋白（CPAP）的约100个氨基酸残基的多肽，编码该多肽的多核苷酸，包含多肽和多核苷酸的组合物及其使用方法。本发明可用于在真核细胞中去稳定微管，包括但不限于癌细胞。

2. 发明授权

US07449563B2 Methods and compositions for destabilizing microtubules 失效
标题翻译：不稳定微管的方法和组合物
公开(公告)号：US07449563B2
公开(公告)日：2008-11-11
申请号：US11003543
申请日：2004-12-03
申请人： Tang K. Tang , Liang-Yi Hung , Ching-Wen Chang
发明人： Tang K. Tang , Liang-Yi Hung , Ching-Wen Chang
IPC分类号： C07H21/04 , C12N15/00 , C12N5/02
CPC分类号： C07K14/47 , A61K38/00
摘要： Polypeptides that comprise an approximately 100-amino acid residue region of a centrosomal P4.1-associated protein (CPAP) that possess microtubule-destabilizing activity, polynucleotides encoding such polypeptides, compositions comprising the polypeptides and polynucleotides, and methods of use thereof, are disclosed. The invention is useful for destabilizing microtubules in eukaryotic cells, including but not limited to cancer cells.
摘要翻译：公开了包含具有微管去稳定活性的中心体P4.1相关蛋白（CPAP）的约100个氨基酸残基的多肽，编码该多肽的多核苷酸，包含多肽和多核苷酸的组合物及其使用方法。本发明可用于在真核细胞中去稳定微管，包括但不限于癌细胞。

3. 发明授权

US06864238B1 Methods and compositions for destabilizing microtubules 失效
公开(公告)号：US06864238B1
公开(公告)日：2005-03-08
申请号：US10680730
申请日：2003-10-06
申请人： Tang K. Tang , Liang-Yi Hung , Ching-Wen Chang
发明人： Tang K. Tang , Liang-Yi Hung , Ching-Wen Chang
IPC分类号： A61K38/00 , C07K14/47
CPC分类号： C07K14/47 , A61K38/00
摘要： Polypeptides that comprise an approximately 100-amino acid residue region of a centrosomal P4.1-associated protein (CPAP) that possess microtubule-destabilizing activity, polynucleotides encoding such polypeptides, compositions comprising the polypeptides and polynucleotides, and methods of use thereof, are disclosed. The invention is useful for destabilizing microtubules in eukaryotic cells, including but not limited to cancer cells.

4. 发明授权

US09032135B2 Data protecting method, memory controller and memory storage device using the same 有权
标题翻译：数据保护方法，内存控制器和使用其的内存存储设备
公开(公告)号：US09032135B2
公开(公告)日：2015-05-12
申请号：US13491607
申请日：2012-06-08
申请人： Ching-Wen Chang
发明人： Ching-Wen Chang
IPC分类号： G06F12/08 , G06F12/14 , G06F12/02
CPC分类号： G06F12/145 , G06F12/0246 , G06F2212/7201
摘要： A data protecting method for a rewritable non-volatile memory module having physical blocks is provided, a plurality of logical block addresses is mapped to a part of the physical blocks. The method includes, configuring a plurality of virtual block addresses to map to the logical block addresses, grouping at least one virtual block address into a virtual block address area, and allocating the virtual block address area to an application. The method also includes, receiving an access command which is configured to instruct accessing a first virtual block address from the application. The method also includes: determining whether the first virtual block address belongs to the virtual block address area, if not, sending an error message to the application. Accordingly, the method can effectively prevent an application from accessing the data which can not be accessed by the application program.
摘要翻译：提供了具有物理块的可重写非易失性存储器模块的数据保护方法，将多个逻辑块地址映射到物理块的一部分。该方法包括：配置多个虚拟块地址以映射到逻辑块地址，将至少一个虚拟块地址分组成虚拟块地址区域，以及将虚拟块地址区域分配给应用。该方法还包括：接收配置为指示从应用访问第一虚拟块地址的访问命令。该方法还包括：确定第一虚拟块地址是否属于虚拟块地址区域，否则，向应用发送错误消息。因此，该方法可以有效地防止应用程序访问应用程序无法访问的数据。

5. 发明授权

US08769309B2 Flash memory storage system, and controller and method for anti-falsifying data thereof 有权
标题翻译：闪存存储系统，以及用于防伪数据的控制器和方法
公开(公告)号：US08769309B2
公开(公告)日：2014-07-01
申请号：US12371820
申请日：2009-02-16
申请人： Ching-Wen Chang
发明人： Ching-Wen Chang
IPC分类号： G06F12/14
CPC分类号： G06F21/572 , H04L9/3234 , H04L9/3239 , H04L2209/56
摘要： A flash memory storage system is provided. The flash memory storage system includes a controller having a rewritable non-volatile memory and a flash memory chip. The rewritable non-volatile memory stores a data token and the flash memory chip stores a security data and a message digest. When the security data in the flash memory chip is updated, the controller updates the data token and generates an eigenvalue, and updates the message digest according to the updated data token and the updated eigenvalue by using a one-way hash function, respectively. When the security data in the flash memory chip is processed by the controller, the controller determinates whether the security data is falsified according to the data token, the eigenvalue and the message digest. In such a way, the security data stored in the flash memory storage system can be effectively protected.
摘要翻译：提供闪存存储系统。闪存存储系统包括具有可重写非易失性存储器和闪存芯片的控制器。可重写非易失性存储器存储数据令牌，闪存芯片存储安全数据和消息摘要。当更新闪速存储器芯片中的安全数据时，控制器更新数据令牌并产生特征值，并且分别通过使用单向散列函数根据更新的数据令牌和更新的特征值来更新消息摘要。当控制器处理闪存芯片中的安全数据时，控制器根据数据令牌，特征值和消息摘要确定安全数据是否被伪造。以这种方式，可以有效地保护存储在闪速存储器存储系统中的安全数据。

6. 发明授权

US08769243B2 Apparatus with smart card chip for storing communication file in non-volatile memory 有权
标题翻译：具有用于在非易失性存储器中存储通信文件的智能卡芯片的装置
公开(公告)号：US08769243B2
公开(公告)日：2014-07-01
申请号：US13426620
申请日：2012-03-22
申请人： Ching-Wen Chang , Huan-Sheng Li
发明人： Ching-Wen Chang , Huan-Sheng Li
IPC分类号： G06F12/02 , G06F12/10
CPC分类号： G06F12/0246 , G06F3/0619 , G06F3/0643 , G06F3/0679 , G06F12/1009 , G06F2212/177 , G06F2212/7202
摘要： A data processing method for a memory storage apparatus having physical blocks is provided. The method includes: grouping the physical blocks into a data area, a spare area and a system area; configuring a plurality of logical addresses which would be formatted into a file allocation table area having cluster entry fields, a root directory area having directory entry fields and a file area having clusters; storing a communication file from the Kth cluster of the file area; recording a file description block corresponding to the communication file in the Mth directory entry field and storing an end of cluster chain mark in the cluster entry field corresponding to the last cluster of the clusters where the communication file stores, and K and M are positive integers which are larger than one. Accordingly, the method can prevent the communication file from being overwritten after the memory storage apparatus is formatted.
摘要翻译：提供一种具有物理块的存储器存储装置的数据处理方法。该方法包括：将物理块分组成数据区，备用区和系统区; 配置将被格式化成具有集群条目字段的文件分配表区域，具有目录条目字段的根目录区域和具有集群的文件区域的多个逻辑地址; 存储来自文件区域的第K个集群的通信文件; 在第M个目录条目字段中记录与该通信文件相对应的文件描述块，并将集群链标记的结束存储在与通信文件存储的集群的最后一个集群相对应的集群条目字段中，并且K和M是正整数大于1。因此，该方法可以防止在格式化存储器存储装置之后通信文件被覆盖。

7. 发明申请

US20130262747A1 DATA WRITING METHOD, AND MEMORY CONTROLLER AND MEMORY STORAGE DEVICE USING THE SAME 有权
标题翻译：数据写入方法，以及使用其的存储器控制器和存储器存储器件
公开(公告)号：US20130262747A1
公开(公告)日：2013-10-03
申请号：US13477068
申请日：2012-05-22
申请人： Ching-Wen Chang
发明人： Ching-Wen Chang
IPC分类号： G06F12/02
CPC分类号： G06F12/0246 , G06F11/1443
摘要： A data writing method for a rewritable non-volatile memory module containing physical blocks is provided. The method includes: configuring virtual block address to map to at least a part of the logical blocks; receiving a write command which instructs to write file data to the first virtual block addresses, and the first virtual block addresses are mapped to first logical blocks of the at least the part of the logical blocks. The method further includes: writing the file data into the physical blocks mapped to a plurality of second logical blocks; determining whether a program failure is occurred during the writing period; and if the program failure is not occurred, the first virtual block addresses are remapped to the second logical block. Accordingly, the method can ensure the update completeness of the file data.
摘要翻译：提供了一种用于包含物理块的可重写非易失性存储器模块的数据写入方法。该方法包括：配置虚拟块地址以映射到至少一部分逻辑块; 接收指令向第一虚拟块地址写入文件数据的写入命令，并且将第一虚拟块地址映射到至少部分逻辑块的第一逻辑块。该方法还包括：将文件数据写入映射到多个第二逻辑块的物理块; 确定写入期间程序故障是否发生; 并且如果没有发生程序故障，则将第一虚拟块地址重新映射到第二逻辑块。因此，该方法可以确保文件数据的更新完整性。

8. 发明授权

US08250288B2 Flash memory storage system and controller and data protection method thereof 有权
标题翻译：闪存存储系统及其控制器及其数据保护方法
公开(公告)号：US08250288B2
公开(公告)日：2012-08-21
申请号：US12353686
申请日：2009-01-14
申请人： Ching-Wen Chang
发明人： Ching-Wen Chang
IPC分类号： G06F13/00 , G06F13/28 , H04L9/32
CPC分类号： G06F21/64
摘要： A flash memory storage system including a controller and a flash memory chip is provided, wherein the controller is disposed with a rewritable non-volatile memory. When the controller writes a security data into the flash memory chip, the controller randomly generates a data token and generates a message digest according to the security data and the data token by using a one-way hash function, wherein the data token and the message digest are respectively stored in the rewritable non-volatile memory and the flash memory chip. Subsequently, when the controller reads the security data from the flash memory chip, the controller determinates whether the security data is falsified according to the data token and the message digest respectively stored in the rewritable non-volatile memory and the flash memory chip. Thereby, the security data in the flash memory chip can be effectively protected.
摘要翻译：提供一种包括控制器和闪速存储器芯片的闪速存储器存储系统，其中控制器配置有可重写的非易失性存储器。当控制器将安全数据写入闪速存储器芯片时，控制器随机地生成数据令牌，并通过使用单向散列函数根据安全数据和数据令牌生成消息摘要，其中数据令牌和消息摘要分别存储在可重写的非易失性存储器和闪存芯片中。随后，当控制器从闪存芯片读取安全数据时，控制器根据分别存储在可重写非易失性存储器和闪存芯片中的数据令牌和消息摘要来确定安全数据是否被伪造。从而可以有效地保护闪存芯片中的安全数据。

9. 发明授权

US08219824B2 Storage apparatus, memory card accessing apparatus and method of reading/writing the same 有权
标题翻译：存储装置，存储卡访问装置及其读/写方法
公开(公告)号：US08219824B2
公开(公告)日：2012-07-10
申请号：US11771112
申请日：2007-06-29
申请人： Ching-Wen Chang
发明人： Ching-Wen Chang
IPC分类号： G06F21/00
CPC分类号： G06F12/1433 , G06F21/31 , G06F21/34
摘要： A storage apparatus having a non-volatile memory and a controller is provided, wherein the non-volatile memory includes a root directory area and a data area, and a password file is stored in the root directory area. The controller identifies a user by using a password in the password file, and the user can access the data area through an encryption/decryption unit of the controller only if the user passes the identification. By using the secured storage apparatus, the risk of the password and encrypted data being cracked is reduced. Accordingly, the protection over the data stored in the storage apparatus is enhanced.
摘要翻译：提供了具有非易失性存储器和控制器的存储装置，其中非易失性存储器包括根目录区域和数据区域，并且密码文件存储在根目录区域中。控制器通过在密码文件中使用密码来识别用户，并且只有在用户通过该标识的情况下，用户才能通过控制器的加密/解密单元来访问数据区域。通过使用安全存储装置，密码和加密数据被破解的风险降低。因此，对存储在存储装置中的数据的保护增强。

10. 发明申请

US20110035602A1 DATA SCRAMBLING, DESCRAMBLING, AND DATA PROCESSING METHOD, AND CONTROLLER AND STORAGE SYSTEM USING THE SAME 有权
标题翻译：数据扫描，DESCRAMBLING和数据处理方法，以及使用它的控制器和存储系统
公开(公告)号：US20110035602A1
公开(公告)日：2011-02-10
申请号：US12565152
申请日：2009-09-23
申请人： Tzu-Yuan Meng , Ching-Wen Chang
发明人： Tzu-Yuan Meng , Ching-Wen Chang
IPC分类号： G06F12/14 , H04L9/00 , G06F12/00
CPC分类号： H04L9/0662 , H04L9/0894
摘要： A data scrambling method for scrambling raw data from a host system is provided. The data scrambling method includes generating a random number and storing the random number into a storage unit. The data scrambling method also includes receiving a user password from the host system, generating a padded value by using a first function unit based on the random number and the user password, and generating a nonce value by using a second function unit based on the padded value and a key. The data scrambling method further includes generating scrambled data corresponding to the raw data by using a third function unit based on the nonce value and the raw data. Accordingly, the raw data of the host system can be effectively protected.
摘要翻译：提供了一种用于对来自主机系统的原始数据进行加扰的数据加扰方法。数据加扰方法包括生成随机数并将随机数存储到存储单元中。数据加密方法还包括从主机系统接收用户密码，通过使用基于随机数和用户密码的第一功能单元生成填充值，并且通过使用第二功能单元，基于填充的价值和关键。数据加扰方法还包括基于随机数值和原始数据通过使用第三功能单元来生成与原始数据相对应的加扰数据。因此，可以有效地保护主机系统的原始数据。

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