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1. 发明授权

US09179889B2 Ultrasonic diagnostic device, and method for measuring initma-media complex thickness 有权
标题翻译：超声波诊断装置以及测量初始 - 媒体复合物厚度的方法
公开(公告)号：US09179889B2
公开(公告)日：2015-11-10
申请号：US13496832
申请日：2010-11-12
申请人： Takenori Fukumoto , Akihiro Kawabata , Makiko Urabe , Takao Suzuki , Yushi Nishimura
发明人： Takenori Fukumoto , Akihiro Kawabata , Makiko Urabe , Takao Suzuki , Yushi Nishimura
IPC分类号： A61B8/02 , A61B8/08
CPC分类号： A61B8/0858 , A61B8/0891 , A61B8/5284
摘要： An ultrasonic diagnostic apparatus according to the present invention includes: an ultrasonic signal processing section, which performs transmission processing for transmitting an ultrasonic wave toward a subject's blood vessel by driving a probe and reception processing for generating a received signal based on the ultrasonic wave reflected from the subject's blood vessel and received at the probe; a tomographic image processing section, which generates a tomographic image based on the received signal; a boundary detecting section, which detects the lumen-intima and media-adventitia boundaries of the blood vessel based on the received signal or the tomographic image; a vascular wall thickness calculating section, which calculates, as a vascular wall thickness value, the interval between the lumen-intima and media-adventitia boundaries detected by the boundary detecting section; a reliability determining section, which determines the reliability of the vascular wall thickness value by a signal feature of the received signal or an image information feature of the tomographic image at a location on the lumen-intima and/or media-adventitia boundaries detected; and a control section, which decides, in accordance with the decision made by the reliability determining section, that the vascular wall thickness value be defined as an intima-media thickness.
摘要翻译：根据本发明的超声波诊断装置包括：超声波信号处理部，其进行用于通过驱动探头向被检者的血管发送超声波的发送处理和基于从所述超声波反射的超声波生成接收信号的接收处理受试者的血管并在探头处接受; 断层图像处理部，其基于所接收的信号生成断层图像; 边界检测部，其基于所接收的信号或断层图像检测血管的内腔和介质 - 外膜边界; 血管壁厚计算部，其计算由所述边界检测部检测出的所述内腔和介质 - 外膜边界之间的间隔作为血管壁厚度值; 可靠性确定部，其通过接收信号的信号特征或者在检测到的管腔内膜和/或介质外膜边界上的位置处的断层图像的图像信息特征来确定血管壁厚值的可靠性; 以及控制部，其根据所述可靠性判定部的判定，判断为血管壁厚值被定义为内膜中间厚度。

2. 发明申请

US20120179042A1 ULTRASONIC DIAGNOSTIC DEVICE, AND METHOD FOR MEASURING INITMA-MEDIA COMPLEX THICKNESS 有权
标题翻译：超声波诊断装置及测量复合材料厚度的方法
公开(公告)号：US20120179042A1
公开(公告)日：2012-07-12
申请号：US13496832
申请日：2010-11-12
申请人： Takenori Fukumoto , Akihiro. Kawabata , Makiko Urabe , Takao Suzuki , Yushi Nishimura
发明人： Takenori Fukumoto , Akihiro. Kawabata , Makiko Urabe , Takao Suzuki , Yushi Nishimura
IPC分类号： A61B8/02 , A61B8/14
CPC分类号： A61B8/0858 , A61B8/0891 , A61B8/5284
摘要： An ultrasonic diagnostic apparatus according to the present invention includes: an ultrasonic signal processing section, which performs transmission processing for transmitting an ultrasonic wave toward a subject's blood vessel by driving a probe and reception processing for generating a received signal based on the ultrasonic wave reflected from the subject's blood vessel and received at the probe; a tomographic image processing section, which generates a tomographic image based on the received signal; a boundary detecting section, which detects the lumen-intima and media-adventitia boundaries of the blood vessel based on the received signal or the tomographic image; a vascular wall thickness calculating section, which calculates, as a vascular wall thickness value, the interval between the lumen-intima and media-adventitia boundaries detected by the boundary detecting section; a reliability determining section, which determines the reliability of the vascular wall thickness value by a signal feature of the received signal or an image information feature of the tomographic image at a location on the lumen-intima and/or media-adventitia boundaries detected; and a control section, which decides, in accordance with the decision made by the reliability determining section, that the vascular wall thickness value be defined as an intima-media thickness.
摘要翻译：根据本发明的超声波诊断装置包括：超声波信号处理部，其进行用于通过驱动探头向被检者的血管发送超声波的发送处理和基于从所述超声波反射的超声波生成接收信号的接收处理受试者的血管并在探头处接受; 断层图像处理部，其基于所接收的信号生成断层图像; 边界检测部，其基于所接收的信号或断层图像检测血管的内腔和介质 - 外膜边界; 血管壁厚计算部，其计算由所述边界检测部检测出的所述内腔和介质 - 外膜边界之间的间隔作为血管壁厚度值; 可靠性确定部，其通过接收信号的信号特征或者在检测到的管腔内膜和/或介质外膜边界上的位置处的断层图像的图像信息特征来确定血管壁厚值的可靠性; 以及控制部，其根据所述可靠性判定部的判定，判断为血管壁厚值被定义为内膜中间厚度。

3. 发明授权

US09770227B2 Ultrasound diagnostic apparatus and ultrasound measurement method using same 有权
公开(公告)号：US09770227B2
公开(公告)日：2017-09-26
申请号：US14000702
申请日：2012-06-07
申请人： Akihiro Kawabata , Manabu Migita , Takenori Fukumoto , Makiko Urabe
发明人： Akihiro Kawabata , Manabu Migita , Takenori Fukumoto , Makiko Urabe
IPC分类号： A61B8/08 , A61B8/00 , A61B8/14
CPC分类号： A61B8/5246 , A61B8/0858 , A61B8/0883 , A61B8/0891 , A61B8/14 , A61B8/483 , A61B8/5223 , A61B8/5284 , A61B8/54 , A61B8/543
摘要： An ultrasonic diagnostic apparatus according to the present disclosure is configured so that a probe including transducers is connectable thereto and performs predetermined measuring processing on a subject's region of interest. The apparatus includes a controller, which performs transmission processing, in which an ultrasonic wave is transmitted toward the subject including the region of interest by driving the probe, and received signal processing, in which frames are generated based on the probe's received signals representing the ultrasonic wave reflected from the subject including the region of interest, a number of times at mutually different times, thereby generating multiple frames, which selects at least two frames under measurement to be subjected to measurement from the multiple frames, which extracts measurable ranges, where the measuring processing can be carried out, based on respective received signals obtained from the region of interest represented in the at least two frames under measurement, and which combines those measurable ranges together to perform predetermined measuring processing on the region of interest.

4. 发明申请

US20130331700A1 ULTRASOUND DIAGNOSTIC APPARATUS AND ULTRASOUND MEASUREMENT METHOD USING SAME 有权
标题翻译：超声波诊断装置和超声波测量方法
公开(公告)号：US20130331700A1
公开(公告)日：2013-12-12
申请号：US14000702
申请日：2012-06-07
申请人： Akihiro Kawabata , Manabu Migita , Takenori Fukumoto , Makiko Urabe
发明人： Akihiro Kawabata , Manabu Migita , Takenori Fukumoto , Makiko Urabe
IPC分类号： A61B8/08 , A61B8/00 , A61B8/14
CPC分类号： A61B8/5246 , A61B8/0858 , A61B8/0883 , A61B8/0891 , A61B8/14 , A61B8/483 , A61B8/5223 , A61B8/5284 , A61B8/54 , A61B8/543
摘要： An ultrasonic diagnostic apparatus according to the present disclosure is configured so that a probe including transducers is connectible thereto and performs predetermined measuring processing on a subject's region of interest. The apparatus includes a controller, which performs transmission processing, in which an ultrasonic wave is transmitted toward the subject including the region of interest by driving the probe, and received signal processing, in which frames are generated based on the probe's received signals representing the ultrasonic wave reflected from the subject including the region of interest, a number of times at mutually different times, thereby generating multiple frames, which selects at least two frames under measurement to be subjected to measurement from the multiple frames, which extracts measurable ranges, where the measuring processing can be carried out, based on respective received signals obtained from the region of interest represented in the at least two frames under measurement, and which combines those measurable ranges together to perform predetermined measuring processing on the region of interest.
摘要翻译：根据本公开的超声波诊断装置被配置为使得包括换能器的探针可连接到其上，并对受检者的感兴趣区域执行预定的测量处理。该装置包括执行传输处理的控制器，其中通过驱动探测器向包括感兴趣区域的对象发送超声波，以及接收信号处理，其中基于探针的表示超声波的接收信号生成帧从包括感兴趣区域的对象反射的波，在相互不同的时间多次，从而生成多个帧，其从多个帧中选择待测量的至少两个帧进行测量，该帧提取可测量的范围，其中可以基于从在测量中的至少两个帧中表示的感兴趣区域获得的各个接收信号进行测量处理，并且将这些可测量范围组合在一起，以对感兴趣的区域执行预定的测量处理。

5. 发明申请

US20120310086A1 ULTRASONIC DIAGNOSTIC DEVICE, AND METHOD FOR MEASURING INTIMA-MEDIA THICKNESS 有权
标题翻译：超声波诊断装置及测量介质厚度的方法
公开(公告)号：US20120310086A1
公开(公告)日：2012-12-06
申请号：US13520214
申请日：2010-11-12
申请人： Takenori Fukumoto , Kazuya Takagi , Takao Suzuki , Akihiro Kawabata
发明人： Takenori Fukumoto , Kazuya Takagi , Takao Suzuki , Akihiro Kawabata
IPC分类号： A61B8/00
CPC分类号： A61B8/0858 , A61B8/0891 , G06T7/12 , G06T7/62 , G06T2207/10132 , G06T2207/30048 , G06T2207/30101
摘要： The present invention provides a method for detecting lumen and adventitia boundaries and measuring an intima-media thickness without depending on the magnitudes of echo intensity variations on the lumen and adventitia sides.The ultrasonic diagnostic apparatus transmits an ultrasonic wave toward a body and obtains biological information based on an echo signal received and includes: an intensity distribution generating section that generates an echo intensity distribution in a depth direction about a vascular wall based on the echo signal; a template generating section that generates a template to detect a boundary based on template data provided in advance to represent a reference pattern of the intensity distribution; a pattern similarity calculating section that changes the depth and intima-media thickness pattern of the template to calculate similarity between the template and the intensity distribution on any change made; and a boundary defining section that defines lumen and adventitia boundaries based on the degree of similarity calculated on any change made.
摘要翻译：本发明提供一种用于检测内腔和外膜边界并测量内膜 - 中膜厚度的方法，而不依赖于内腔和外膜侧的回波强度变化的大小。所述超声波诊断装置向身体发送超声波，并且基于所接收的回波信号获得生物信息，并且包括：强度分布生成部，其基于所述回波信号生成围绕血管壁的深度方向的回波强度分布; 模板生成部，其基于预先提供的表示强度分布的参照图案的模板数据，生成检测边界的模板; 模式相似度计算部分，改变模板的深度和中内层厚度模式，以计算模板与强度分布之间的相似性; 以及基于根据任何改变而计算出的相似程度来定义腔和外膜边界的边界限定部分。

6. 发明授权

US08740796B2 Ultrasonic diagnostic device, and method for measuring intima-media thickness 有权
标题翻译：超声诊断装置以及内膜厚度测定方法
公开(公告)号：US08740796B2
公开(公告)日：2014-06-03
申请号：US13520214
申请日：2010-11-12
申请人： Takenori Fukumoto , Kazuya Takagi , Takao Suzuki , Akihiro Kawabata
发明人： Takenori Fukumoto , Kazuya Takagi , Takao Suzuki , Akihiro Kawabata
IPC分类号： A61B8/00 , G06K9/00
CPC分类号： A61B8/0858 , A61B8/0891 , G06T7/12 , G06T7/62 , G06T2207/10132 , G06T2207/30048 , G06T2207/30101
摘要： An ultrasonic diagnostic apparatus transmits an ultrasonic wave toward a body and obtains biological information based on an echo signal received and includes: an intensity distribution generating section that generates an echo intensity distribution in a depth direction about a vascular wall based on the echo signal; a template generating section that generates a template to detect a boundary based on template data provided in advance to represent a reference pattern of the intensity distribution; a pattern similarity calculating section that changes the depth and intima-media thickness pattern of the template to calculate similarity between the template and the intensity distribution on any change made; and a boundary defining section that defines lumen and adventitia boundaries based on the degree of similarity calculated on any change made. The intima-media thickness is thus determined without depending on the magnitudes of echo intensity variations on the lumen and adventitia sides.
摘要翻译：超声波诊断装置向身体发送超声波，并且基于接收到的回波信号获取生物信息，并且包括：强度分布生成部，其基于回波信号，在血管壁周围的深度方向生成回波强度分布; 模板生成部，其基于预先提供的表示强度分布的参照图案的模板数据，生成检测边界的模板; 模式相似度计算部分，改变模板的深度和中内层厚度模式，以计算模板与强度分布之间的相似性; 以及基于根据任何改变而计算出的相似程度来定义腔和外膜边界的边界限定部分。因此确定内膜 - 中膜厚度，而不依赖于内腔和外膜侧的回波强度变化的大小。

7. 发明申请

US20110015524A1 ULTRASONOGRAPH 有权
公开(公告)号：US20110015524A1
公开(公告)日：2011-01-20
申请号：US12933129
申请日：2008-07-30
申请人： Takao Suzuki , Takenori Fukumoto
发明人： Takao Suzuki , Takenori Fukumoto
IPC分类号： A61B8/14
CPC分类号： A61B8/0858 , A61B5/7289 , A61B8/485
摘要： An ultrasonic diagnostic apparatus includes: a transmitting section for driving a probe to send out ultrasonic waves toward a subject one after another; a receiving section for getting an echo, produced as a result of reflection of each ultrasonic wave from the subject, received by the probe, thereby generating a received signal; a tissue tracking section for generating position tracking waveforms, each representing the positional displacement of an associated one of measuring points on the subject, based on the received signals; a boundary detecting section for determining the boundary location of the subject's tissue; a tracking waveform choosing section for choosing at least two position tracking waveforms, including the one associated with the boundary, from the position tracking waveforms by reference to at least one of the waveforms associated with the measuring points, the location of the boundary, and the amplitudes of the received signals; and a tissue attribute value calculating section for calculating a tissue attribute value of the subject using the position tracking waveforms chosen.
摘要翻译：一种超声波诊断装置，包括：发送部，其用于驱动探头，朝向对象一个接一个地发送超声波; 用于获得由探头接收的每个超声波的反射的结果产生的回波的接收部分，从而产生接收信号; 组织跟踪部分，用于基于所接收的信号产生位置跟踪波形，每个位置跟踪波形表示对象上相关联的一个测量点的位置偏移; 边界检测部分，用于确定被检者的组织的边界位置; 跟踪波形选择部分，用于通过参考与测量点相关联的至少一个波形，边界的位置和边界的位置，从位置跟踪波形中选择包括与边界相关联的至少两个位置跟踪波形接收信号的振幅; 以及组织属性值计算部分，用于使用所选择的位置跟踪波形来计算对象的组织属性值。

8. 发明申请

US20090163811A1 ULTRASONOGRAPH 审中-公开
公开(公告)号：US20090163811A1
公开(公告)日：2009-06-25
申请号：US12293520
申请日：2007-03-13
申请人： Takenori Fukumoto , Hisashi Hagiwara , Takao Suzuki
发明人： Takenori Fukumoto , Hisashi Hagiwara , Takao Suzuki
IPC分类号： A61B8/14
CPC分类号： A61B8/0858 , A61B5/02007 , A61B8/485 , G01S7/52036 , G01S7/52042
摘要： The present invention is to provide an ultrasonograph which can accurately measure an IMT value of a blood vessel by using an ultrasonic wave. The ultrasonograph includes an ultrasonic signal emitting unit (1) for emitting an ultrasonic signal, an ultrasonic echo receiving unit (2) for receiving, as a reflected signal, an ultrasonic echo from inside tissue, and converting the ultrasonic echo into an electronic signal, an amplitude information processing unit (5) for processing amplitude information on the ultrasonic echo, a phase information processing unit (6) for processing phase information of the ultrasonic echo, and a boundary detecting unit (7) for determining a distribution of a boundary between a blood flow region and an intima and a boundary between a media and an adventitia on the basis of at least one processing result output from the amplitude information processing unit and at least one processing result output from the phase information processing unit, and an IMT value calculating unit (9) for computing an IMT value of a blood vessel from position information indicative of the position of the boundary between the blood flow region and the intima and position information indicative of the position of the boundary between the media and the adventitia.
摘要翻译：本发明提供一种能够通过超声波精确地测定血管的IMT值的超声波诊断装置。所述超声波诊断装置包括用于发射超声信号的超声波信号发射单元（1），用于从内部组织接收来自内部组织的超声回波作为反射信号的超声波回波接收单元（2），并将超声波回波转换为电子信号，用于处理关于超声回波的振幅信息的振幅信息处理单元（5），用于处理超声波回波的相位信息的相位信息处理单元（6），以及用于确定超声回波的边界分布的边界检测单元基于从振幅信息处理单元输出的至少一个处理结果和从相位信息处理单元输出的至少一个处理结果，媒体和外膜之间的血流区域和内膜以及边界，以及IMT值计算单元（9），用于根据表示t之间的边界的位置的位置信息计算血管的IMT值他的血流区域和指示介质与外膜之间边界位置的内膜和位置信息。

9. 发明授权

US08469889B2 Ultrasonograph that chooses tracking waveforms for attribute value calculations 有权
标题翻译：选择属性值计算的跟踪波形的超声波检查仪
公开(公告)号：US08469889B2
公开(公告)日：2013-06-25
申请号：US12933129
申请日：2008-07-30
申请人： Takao Suzuki , Takenori Fukumoto
发明人： Takao Suzuki , Takenori Fukumoto
IPC分类号： A61B8/00
CPC分类号： A61B8/0858 , A61B5/7289 , A61B8/485
摘要： An ultrasonic diagnostic apparatus includes: a transmitting section for driving a probe to send out ultrasonic waves toward a subject one after another; a receiving section for getting an echo, produced as a result of reflection of each ultrasonic wave from the subject, received by the probe, thereby generating a received signal; a tissue tracking section for generating position tracking waveforms, each representing the positional displacement of an associated one of measuring points on the subject, based on the received signals; a boundary detecting section for determining the boundary location of the subject's tissue; a tracking waveform choosing section for choosing at least two position tracking waveforms, including the one associated with the boundary, from the position tracking waveforms by reference to at least one of the waveforms associated with the measuring points, the location of the boundary, and the amplitudes of the received signals; and a tissue attribute value calculating section for calculating a tissue attribute value of the subject using the position tracking waveforms chosen.
摘要翻译：一种超声波诊断装置，包括：发送部，其用于驱动探头，朝向对象一个接一个地发送超声波; 用于获得由探头接收的每个超声波的反射的结果产生的回波的接收部分，从而产生接收信号; 组织跟踪部分，用于基于所接收的信号产生位置跟踪波形，每个位置跟踪波形表示对象上相关联的一个测量点的位置偏移; 边界检测部分，用于确定被检者的组织的边界位置; 跟踪波形选择部分，用于通过参考与测量点相关联的至少一个波形，边界的位置和边界的位置，从位置跟踪波形中选择包括与边界相关联的至少两个位置跟踪波形接收信号的振幅; 以及组织属性值计算部分，用于使用所选择的位置跟踪波形来计算对象的组织属性值。

10. 发明申请

US20100185090A1 ULTRASONOGRAPHIC DEVICE 审中-公开
标题翻译：超声波设备
公开(公告)号：US20100185090A1
公开(公告)日：2010-07-22
申请号：US12669544
申请日：2008-07-14
申请人： Takao Suzuki , Makoto Kato , Masahiko Kadokura , Takenori Fukumoto
发明人： Takao Suzuki , Makoto Kato , Masahiko Kadokura , Takenori Fukumoto
IPC分类号： A61B8/14
CPC分类号： A61B8/14 , A61B8/0858 , A61B8/485 , A61B8/543 , G01S7/52036 , G01S7/52071 , G01S7/52073 , G01S15/8906
摘要： An ultrasonic diagnostic apparatus that can make accurate and highly reliable measurements is provided.The apparatus includes: a transmitting section for driving an ultrasonic probe to transmit an ultrasonic wave toward a vital tissue; a receiving section for receiving a reflected wave, produced by getting the ultrasonic wave reflected by the tissue, at the probe to generate a received signal; an image generating section for generating a tomographic image representing the intensity of the received signal on each acoustic line of the ultrasonic wave; a shape measured value calculating section for calculating, based on the received signal, the magnitudes of displacements at measuring points on the tissue; a determining section for determining a degree of reliability of measurement on at least some acoustic lines of the ultrasonic wave by comparing variations in the brightness of a tomographic image, associated with the acoustic lines of the ultrasonic wave, and/or the magnitudes of displacements, with a reference set in advance about the reliability of the received signal; and a display section for displaying the tomographic image and the result of a decision on the degree of reliability.
摘要翻译：提供了可以进行精确和高度可靠的测量的超声波诊断装置。该装置包括：发送部分，用于驱动超声波探头以向生命组织传送超声波; 接收部分，用于接收由所述组织反射的超声波产生的反射波，以产生接收信号; 图像生成部，其生成表示超声波的各声线上的接收信号的强度的断层图像; 形状测量值计算部分，用于基于所接收的信号计算组织上测量点处的位移大小; 确定部，用于通过比较与超声波的声线相关联的断层图像的亮度和/或位移的大小来确定超声波的至少一些声线上的测量的可靠度，预先设定关于接收信号的可靠性的参考; 以及用于显示断层图像的显示部分和关于可靠度的决定的结果。

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