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1. 发明授权

US4512348A Device for automatically and continuously measuring the constituent parts of blood 失效
标题翻译：用于自动连续测量血液成分的装置
公开(公告)号：US4512348A
公开(公告)日：1985-04-23
申请号：US371482
申请日：1982-04-23
申请人： Takatoshi Uchigaki , Akio Saito , Naoki Yamada
发明人： Takatoshi Uchigaki , Akio Saito , Naoki Yamada
IPC分类号： A61B5/00 , A61B5/155 , A61M1/36 , G01N33/48 , G01N33/483 , G01N33/487 , G01N
CPC分类号： G01N33/48 , A61B5/14865 , A61B5/15003 , A61B5/150229 , A61B5/150992 , A61B5/155 , A61M1/3672
摘要： At the time of drawing the blood continuously from the vein of the patient by means of a catheter and measuring the concentration of a specified constituent part contained in the blood automatically and continuously for long hours, the sample liquid and two sorts of correcting liquids (standard liquid I and base liquid) are sucked by a single sampling nozzle in prescribed order and are supplied to the measuring section through a common channel. Each of the liquids are diluted with a buffer solution at the identical rate with the manifold in the measuring section, are separated from one another through the interposition of air layers among them, and supplied to a sensor. The outputs of the measured sample liquid from the sensor are corrected by the outputs of each of the neighboring measured correcting liquids in succession and are displayed as measured values. In the blood-drawing section, there is used a double-current catheter having the first and second catheter arrangements which are constructed so as to be incorporated directly into the tube pump.
摘要翻译：在通过导管从患者的静脉连续抽取血液时，长时间自动连续测量血液中所含有的特定组成部分的浓度，将样品液和两种校正液（标准液体I和基础液体）以规定的顺序由单个采样喷嘴吸入，并通过公共通道供给到测量部。每个液体以与测量部分中的歧管相同的速率用缓冲溶液稀释，通过在它们之间插入空气层而彼此分离，并提供给传感器。来自传感器的测量样品液体的输出通过相邻测量校正液中的每一个的输出被连续校正，并且被显示为测量值。在抽血部分中，使用具有第一和第二导管装置的双流导管，其构造成直接结合在管泵中。

2. 发明授权

US5266179A Quantitative analysis method and its system using a disposable sensor 失效
标题翻译：定量分析方法及其使用一次性传感器的系统
公开(公告)号：US5266179A
公开(公告)日：1993-11-30
申请号：US733130
申请日：1991-07-19
申请人： Shiro Nankai , Mariko Kawaguri , Toshihiko Yoshioka , Haruhiro Tsutsumi , Kyozo Terao , Naoki Tanimoto , Masahiro Yoshioka , Hiroshi Hyodo , Takatoshi Uchigaki
发明人： Shiro Nankai , Mariko Kawaguri , Toshihiko Yoshioka , Haruhiro Tsutsumi , Kyozo Terao , Naoki Tanimoto , Masahiro Yoshioka , Hiroshi Hyodo , Takatoshi Uchigaki
IPC分类号： G01N27/26 , G01N27/28 , G01N27/416 , G01N27/49
CPC分类号： G01N33/48771 , G01N2035/009
摘要： A sensor 13 is inserted into a connector 14. A constant voltage required to obtain a response current is applied across the connector 14 by a voltage applying source 15 at timings required. A response current of the sensor 13 inserted into the connector 14 is converted into a voltage by a current-to-voltage converter 16, and the amount thereof is determined by a microcomputer, the analysis results being displayed onto a display unit.

3. 发明授权

US07131984B2 Lancing device, method of making lancing device, pump mechanism, and sucking device 失效
标题翻译：起搏装置，采血装置的方法，泵机构，以及抽吸装置
公开(公告)号：US07131984B2
公开(公告)日：2006-11-07
申请号：US10466146
申请日：2002-01-11
申请人： Yoshiharu Sato , Etsuo Hirao , Masahiro Fukuzawa , Takatoshi Uchigaki
发明人： Yoshiharu Sato , Etsuo Hirao , Masahiro Fukuzawa , Takatoshi Uchigaki
IPC分类号： A61B17/14
CPC分类号： A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150412 , A61B5/150503 , A61B5/15113 , A61B5/15117 , A61B5/15186 , A61B5/1519 , A61B5/15194
摘要： A lancing device according to the present invention includes: a housing; a moving body movable relatively to the housing for forward movement of a needle; a driving mechanism for forward movement of the moving body; a hollow pressing portion at a front end of the housing for contact with a part where a puncture is to be made; and a pump mechanism capable of causing a vacuum to act inside the pressing portion. The pump mechanism is capable of adjusting the vacuum. The pump mechanism includes for example: a moving portion capable of reciprocating in a first direction and a second direction away from the first direction. Preferably, the adjustment of the vacuum is made by changing the number of reciprocations of the moving part in the first and the second directions.
摘要翻译：根据本发明的采血装置包括：壳体; 可相对于壳体移动的移动体，用于针的向前运动; 用于移动体向前运动的驱动机构; 在壳体的前端处与要进行穿刺的部分接触的中空按压部分; 以及能够在按压部内部进行真空的泵机构。泵机构能够调节真空度。泵机构包括例如：能够沿第一方向往复移动的移动部分和远离第一方向的第二方向。优选地，通过改变第一和第二方向上的运动部件的往复运动次数来进行真空的调节。

4. 发明授权

US06830551B1 Body fluid measuring instrument and body fluid sampler thereof 失效
标题翻译：体液测量仪及其体液取样器
公开(公告)号：US06830551B1
公开(公告)日：2004-12-14
申请号：US10129155
申请日：2002-07-22
申请人： Takatoshi Uchigaki , Kohei Ishida , Shiro Matsuoka
发明人： Takatoshi Uchigaki , Kohei Ishida , Shiro Matsuoka
IPC分类号： A61B500
CPC分类号： A61B5/1486 , A61B5/14532 , A61B5/150022 , A61B5/150427 , A61B5/15113 , A61B5/15117 , A61B5/15198 , A61B5/157
摘要： A body fluid measuring apparatus includes a main body (20) and a body fluid sampler (30) attached to the main body (20). The body fluid sampler (30) includes a fixed member (35) fixed to the main body (20) and a movable member guided by the fixed member (35). The fixed member (35) is provided with a body fluid-sucking chamber (39) open at the tip of the fixed member (35) and a through-hole communicating therewith. The movable member (31) includes a lancet (32) acting as a first electrode and is reciprocatively movable for bringing the tip of the lancet (32) into and out of the tip of the fixed member (35). The body fluid-sucking chamber (39) is provided with a second electrode (36) and a reactive layer containing a reactive reagent necessary for measurement. The main body (20) includes an electronic circuit (24) for determining a measured value on the basis of an electrical signal from the lancet (32) as the first electrode and a second electrode. The main body also includes a drive mechanism (43) which drives the movable member for causing the tip of the lancet to project from the tip of the fixed member.
摘要翻译：体液测量装置包括主体（20）和附接到主体（20）的体液取样器（30）。体液取样器（30）包括固定到主体（20）的固定构件（35）和由固定构件（35）引导的可动构件。固定部件（35）设置有在固定部件（35）的前端开口的体液吸入室（39）和与其连通的贯通孔。可动构件（31）具有作为第一电极的柳叶刀（32），并且能够使刺血针（32）的前端进入固定部件（35）的前端部并使其移出。体液吸入室（39）具有第二电极（36）和含有测定所需的反应试剂的反应层。主体（20）包括用于基于来自作为第一电极的刺血针（32）的电信号和第二电极来确定测量值的电子电路（24）。主体还包括驱动机构（43），该驱动机构（43）驱动可动部件使刺血针的尖端从固定部件的前端突出。

5. 发明授权

US5270006A Automatic sample analyzer 失效
标题翻译：自动样品分析仪
公开(公告)号：US5270006A
公开(公告)日：1993-12-14
申请号：US754002
申请日：1991-09-03
申请人： Takatoshi Uchigaki , Yasumitsu Takagi , Hideki Nishimura
发明人： Takatoshi Uchigaki , Yasumitsu Takagi , Hideki Nishimura
IPC分类号： G01N33/493 , G01N33/52 , G01N35/00 , G01N35/02 , G01N33/00
CPC分类号： G01N35/00029 , G01N2035/00039 , G01N2035/00089 , G01N2035/00118 , G01N2035/00752
摘要： An automatic sample analyzer comprising, a plurality of sticks which have a plurality of reagent portions corresponding to different examination items so as to be divided into a plurality of groups of sticks by combinations of the examination items, a plurality of cassettes each having an outlet and a discriminatory mark, the discriminatory mark corresponding to one of the group of the sticks so as to accommodate the one of the group of the sticks, a removal device for automatically taking a desired one of the sticks of the cassettes by using a single removal mechanism.

6. 发明授权

US07790106B2 Sensor cartridge, sensor feeder, and measuring instrument 有权
标题翻译：传感器墨盒，传感器进纸器和测量仪器
公开(公告)号：US07790106B2
公开(公告)日：2010-09-07
申请号：US12274912
申请日：2008-11-20
申请人： Takatoshi Uchigaki , Takao Fukuoka , Yasuhide Kusaka , Katsumi Hamamoto
发明人： Takatoshi Uchigaki , Takao Fukuoka , Yasuhide Kusaka , Katsumi Hamamoto
IPC分类号： G01N33/00
CPC分类号： G01N33/48757 , B01L9/52 , B01L2300/0825
摘要： A sensor cartridge (1) for use on a sensor feeder includes a cartridge body (10) and a mold (12). The cartridge body (10) has an upper surface (10a), a front (10c) extending continuously from the upper surface, and a plurality of sensor-holding slots (11). Each of the sensor-holding slots (11) includes a first opening formed in the upper surface (10a) and a second opening formed in the front (10c) and communicating with the first opening. The mold (12) closes the first opening and second openings in case sensors are charged in the sensor-holding slots (11).
摘要翻译：用于传感器馈送器的传感器盒（1）包括盒体（10）和模具（12）。盒体（10）具有上表面（10a），从上表面连续延伸的前（10c）和多个传感器保持槽（11）。每个传感器保持槽（11）包括形成在上表面（10a）中的第一开口和形成在前面（10c）中并与第一开口连通的第二开口。在传感器保持槽（11）中，传感器被充电的情况下，模具（12）封闭第一开口和第二开口。

7. 发明授权

US07297152B2 Lancing apparatus 失效
标题翻译：打捞机
公开(公告)号：US07297152B2
公开(公告)日：2007-11-20
申请号：US10493984
申请日：2002-10-25
申请人： Masahiro Fukuzawa , Masufumi Koike , Takatoshi Uchigaki
发明人： Masahiro Fukuzawa , Masufumi Koike , Takatoshi Uchigaki
IPC分类号： A61B17/32
CPC分类号： A61B5/150022 , A61B5/150099 , A61B5/15019 , A61B5/150213 , A61B5/150221 , A61B5/150412 , A61B5/150503 , A61B5/15113 , A61B5/15117 , A61B5/1519 , A61B5/15194
摘要： The present invention relates to a lancing apparatus (A) comprising an apparatus body (1) including a housing (5) and a movable member for advancing a needle (40b), the movable member being arranged movably in the housing (5), and a plurality of front end covers (2, 3) each for coming into contact with a portion to be lanced in lancing. Preferably, the plurality of front end covers (2, 3) have different structures adapted for lancing different portions and are removably attachable to a same portion of the apparatus body (1) individually. A suitable cover (2 or 3) for the portion to be lanced is selectable from the front end covers (2, 3), and the selected front end cover (2 or 3) is attached to the apparatus body (1) in use.
摘要翻译：本发明涉及一种包括装置主体（1）的采血装置（A），该装置主体（1）包括壳体（5）和用于使针（40b）前进的可动构件，所述可动构件可移动地布置在所述壳体中，以及多个前端盖（2,3），每个前端盖（2,3）与要切割的部分接触。优选地，多个前端盖（2,3）具有不同的结构，其适用于切割不同部分，并且可移除地附接到装置本体（1）的相同部分。可以从前端盖（2,3）选择用于待切割部分的合适的盖（2或3），并且所选择的前端盖（2或3）在使用中附接到设备主体（1）。

8. 发明授权

US5038021A Analyzing device 失效
标题翻译：分析设备
公开(公告)号：US5038021A
公开(公告)日：1991-08-06
申请号：US514932
申请日：1990-04-26
申请人： Takatoshi Uchigaki , Yoshito Komada , Yasumitsu Takagi
发明人： Takatoshi Uchigaki , Yoshito Komada , Yasumitsu Takagi
IPC分类号： G01N35/02 , G01N33/487 , G01N33/49 , G01N35/00
CPC分类号： G01N35/00029 , G01N2035/00039 , G01N2035/00138 , G01N2035/00752
摘要： An analyzng device comprises a plate holding table, a shifting mechanism for shifting the plate holding table, bar code reading sensors, and a detecting unit for detecting the signals based on the drops of the solutions in the plate set on the plate holding table located in the plate measurement position. When the data of the bar code read by the bar code reading sensor is not fit for a predetermined measurement condition, the plate holding table is shifted to the plate exhausting position. On the other hand, when the data of the bar code is fit for the predetermined measurement condition, the plate holding table is shifted to the solution pipetting position and when the pipetting of the solutions is finished, the plate holding table is further shifted to the mesurement position. When the concentration of substance in the test solution is completed by the detecting unit, the plate holding table is shifted to the plate exhausting position.

9. 发明授权

US4304119A Method and device for measuring the freezing point lowering 失效
标题翻译：用于测量冰点降低的方法和装置
公开(公告)号：US4304119A
公开(公告)日：1981-12-08
申请号：US076552
申请日：1979-09-18
申请人： Takatoshi Uchigaki
发明人： Takatoshi Uchigaki
IPC分类号： G01N13/04 , A61M1/14 , G01N25/04 , G01N25/06 , G01N33/48 , G01N33/483 , G01N33/86
CPC分类号： G01N25/04
摘要： A method and device for measuring the osmotic pressure on the basis of an improved supercooling process, whereby and wherein cryohydrate nuclei are made to generate almost spontaneously in a part of a sample liquid by cooling the above part down further to a temperature (to an extra-supercooled state) lower than the temperature of a supercooled state, wherethrough the sample liquid as a whole is induced to freeze statically. Because of a non-necessity of using any stirring rod, it becomes possible to design a small-sized device, to reduce the sample liquid to be used to a possible infinitesimal, and further to perform the continuous measurement with the aid of the adoption of a flow cell.
摘要翻译：一种用于基于改进的过冷却过程来测量渗透压的方法和装置，由此通过将上述部分进一步冷却至一个温度（一个额外的温度），使冷冻水核几乎自发地在一部分样品液体中产生 - 过冷状态）低于过冷状态的温度，通过样品液体作为整体被诱导静止地冷冻。由于不需要使用任何搅拌棒，因此可以设计小尺寸的装置，以将样品液体减少到可能的无穷小，并且进一步在采用流动池。

10. 发明授权

US07758602B2 Lancing device, method of making lancing device, pump mechanism, and sucking device 失效
标题翻译：起搏装置，采血装置的方法，泵机构，以及抽吸装置
公开(公告)号：US07758602B2
公开(公告)日：2010-07-20
申请号：US11523160
申请日：2006-09-19
申请人： Yoshiharu Sato , Etsuo Hirao , Masahiro Fukuzawa , Takatoshi Uchigaki
发明人： Yoshiharu Sato , Etsuo Hirao , Masahiro Fukuzawa , Takatoshi Uchigaki
IPC分类号： A61B17/14
CPC分类号： A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150412 , A61B5/150503 , A61B5/15113 , A61B5/15117 , A61B5/15186 , A61B5/1519 , A61B5/15194
摘要： A lancing device according to the present invention includes: a housing; a moving body movable relatively to the housing for forward movement of a needle; a driving mechanism for forward movement of the moving body; a hollow pressing portion at a front end of the housing for contact with a part where a puncture is to be made; and a pump mechanism capable of causing a vacuum to act inside the pressing portion. The pump mechanism is capable of adjusting the vacuum. The pump mechanism includes for example: a moving portion capable of reciprocating in a first direction and a second direction away from the first direction. Preferably, the adjustment of the vacuum is made by changing the number of reciprocations of the moving part in the first and the second directions.
摘要翻译：根据本发明的采血装置包括：壳体; 可相对于壳体移动的移动体，用于针的向前运动; 用于移动体向前运动的驱动机构; 在壳体的前端处与要进行穿刺的部分接触的中空按压部分; 以及能够在按压部内部进行真空的泵机构。泵机构能够调节真空度。泵机构包括例如：能够沿第一方向往复移动的移动部分和远离第一方向的第二方向。优选地，通过改变第一和第二方向上的运动部件的往复运动次数来进行真空的调节。

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