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    • 4. 发明申请
    • TARGET SUBSTANCE DETECTION CHIP, TARGET SUBSTANCE DETECTION PLATE, TARGET SUBSTANCE DETECTION DEVICE AND TARGET SUBSTANCE DETECTION METHOD
    • 目标物质检测芯片,目标物质检测板,目标物质检测装置和目标物质检测方法
    • US20140170024A1
    • 2014-06-19
    • US14232530
    • 2012-07-03
    • Makoto FujimakiNobuko FukudaKenichi NomuraHidenori NagaiToshihiko Ooie
    • Makoto FujimakiNobuko FukudaKenichi NomuraHidenori NagaiToshihiko Ooie
    • G01N33/543
    • G01N33/54373G01N21/553G01N21/6428G01N21/648G01N2021/6439
    • [Problem] To provide a target substance detection chip, a target substance detection device, and a target substance detection method, that can be manufactured easily in a small size at low costs with reduction of the number of parts involved in the detection chip constituted by an optical prism and a detection plate used for a SPR sensor and an optical waveguide mode sensor, that can detect a target substance quickly with high sensitivity, and in which an analyte liquid is easily delivered.[Solution] A target substance detection chip of the present invention includes: a plate-like transparent base portion which allows light to pass therethrough; and a flow path which is formed in one surface of the transparent base portion as a groove and through which an analyte liquid verifying a presence of a target substance is delivered in a length direction of the groove, wherein the flow path is formed such that at least an electric field enhancement layer is disposed on an inner surface of a groove portion formed to at least partly have inclined surfaces appearing in cross section to be inclined at a gradient to the surface of the transparent base portion, and wherein a part or entirety of an uppermost surface of the groove which contacts the analyte liquid serves as a detection surface for the target substance.
    • 本发明提供能够以低成本容易地制造的目标物质检测装置,目标物质检测装置以及目标物质检测方法,能够减少由 用于SPR传感器和光波导模式传感器的光学棱镜和检测板,其能够以高灵敏度快速检测目标物质,并且其中分析物液体容易传送。 [解决方案]本发明的目标物质检测芯片包括:允许光通过的板状透明基部; 以及在所述透明基部的一个表面中形成为沟槽的流路,并且通过所述流路在所述槽的长度方向上输送检验目标物质的存在的分析液,所述流路形成为: 至少一个电场增强层设置在凹槽部分的内表面上,所述凹槽部分的内表面形成为至少部分地具有倾斜表面,该倾斜表面呈现出与透明基底部分的表面倾斜的斜面,并且其中部分或全部 与分析液接触的槽的最上表面作为目标物质的检测面。