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1. 发明授权

US06841583B2 Composition and uses thereof 有权
标题翻译：组合物及其用途
公开(公告)号：US06841583B2
公开(公告)日：2005-01-11
申请号：US10218604
申请日：2002-08-15
申请人： Takanori Sueda , Masayoshi Yamaguchi , Atsushi Komoriya , Kouichi Kizu
发明人： Takanori Sueda , Masayoshi Yamaguchi , Atsushi Komoriya , Kouichi Kizu
IPC分类号： C08F2/00 , C08J9/04 , C08L23/04 , C08L23/08 , C08J9/00
CPC分类号： C08J9/04 , C08J2323/08 , C08L23/04 , C08L23/0815 , C08L2203/14 , C08L2205/02 , Y10T428/249954 , Y10T428/249958 , Y10T428/249993 , Y10T428/31573 , Y10T428/31587 , Y10T428/4935 , C08L2666/04
摘要： A composition that has an ethylene/α-olefin copolymer (A), a blowing agent (B), and optionally, an organic peroxide and a crosslinking assistant. The ethylene/α-olefin copolymer (A) has an ethylene/α-olefin copolymer (A1) having a density of not less than 0.880 g/cm3 and less than 0.900 g/cm3 and MFR (190° C.) of 0.1 to 50 g/10 min and an ethylene/α-olefin copolymer (A2) having a density of 0.900 to 0.930 g/cm3, MFR (190° C.) of 0.1 to 50 g/10 min and a main melting point peak at a position of not higher than 110° C., in a specific ratio. A foamed product, obtained by heat treatment of the composition, may be further subjected to secondary compression. A laminate made of the foamed product and a layer made of a polyolefin, a polyurethane, a rubber, a leather or an artificial leather. Footwear or a footwear part made of the foamed product or the laminate.
摘要翻译：具有乙烯/α-烯烃共聚物（A），发泡剂（B）和任选的有机过氧化物和交联助剂的组合物。乙烯/α-烯烃共聚物（A）具有密度不小于0.880g / cm 3且小于0.900g / cm 3的乙烯/α-烯烃共聚物（A1）和MFR（190° C）为0.1〜50g / 10min，密度为0.900〜0.930g / cm 3的乙烯/α-烯烃共聚物（A2），MFR（190℃）为0.1〜50g / 10 min，特定比例为不高于110℃的主熔点峰。通过组合物的热处理获得的发泡产品可以进一步进行二次压缩。由发泡产品制成的层压材料和由聚烯烃，聚氨酯，橡胶，皮革或人造革制成的层。鞋类或由发泡制品或层压制成的鞋类部件。

2. 发明授权

US07259211B2 Ethylene type ternary copolymer and propylene type resin composition 有权
标题翻译：乙烯型三元共聚物和丙烯类树脂组合物
公开(公告)号：US07259211B2
公开(公告)日：2007-08-21
申请号：US10996435
申请日：2004-11-26
申请人： Kouichi Kizu , Keiji Okada , Masayoshi Yamaguchi
发明人： Kouichi Kizu , Keiji Okada , Masayoshi Yamaguchi
IPC分类号： C08L23/00
CPC分类号： C08F210/16 , C08F210/06 , C08F210/14 , C08F2500/12 , C08F2500/03 , C08F2500/08 , C08F2500/17 , C08F210/08
摘要： (i) A material is developed which modifies the rigidity, tensile elongation at break and impact resistance of resins such as a polypropylene resin when used as a modifier. The invention relates to an ethylene type ternary copolymer (A) comprising (i) an ethylene, propylene or 1-butene and a higher α-olefin having 6 to 20 carbon atoms, wherein the content of ethylene is 70 to 89 mol %, the content of propylene or 1-butene is 10 to 22 mol % and the content of a higher α-olefin having 6 to 20 carbon atoms is 1 to 11 mol % and the molar ratio of the higher-olefin having 6 to 20 carbon atoms to the structural units except for ethylene (either propylene or 1-butene and the higher α-olefin having 6 to 20 carbon atoms) is 1/10 to 5/10 and the ethylene type ternary copolymer has a density of 0.857 to 0.885 g/cm3. The invention also relates to (ii) a propylene type resin composition comprising a propylene type polymer (B), the ethylene type ternary copolymer (A) and an inorganic filler (C).
摘要翻译：（i）开发了当用作改性剂时改性树脂如聚丙烯树脂的刚性，断裂拉伸伸长率和耐冲击性的材料。本发明涉及一种乙烯型三元共聚物（A），其包含（i）乙烯，丙烯或1-丁烯和具有6至20个碳原子的较高级α-烯烃，其中乙烯的含量为70至89摩尔％，丙烯或1-丁烯的含量为10〜22摩尔％，碳原子数6〜20的高级α-烯烃的含量为1〜11摩尔％，碳原子数为6〜20的高级烯烃的摩尔比为乙烯（丙烯或1-丁烯和碳原子数6〜20的高级α-烯烃）以外的结构单元为1/10〜5/10，乙烯型三元共聚物的密度为0.857〜0.885g / cm 3 ^{3 。本发明还涉及（ii）包含丙烯类聚合物（B），乙烯型三元共聚物（A）和无机填料（C）的丙烯类树脂组合物。}

3. 发明申请

US20050131158A1 Ethylene type ternary copolymer and propylene type resin composition 有权
标题翻译：乙烯型三元共聚物和丙烯类树脂组合物
公开(公告)号：US20050131158A1
公开(公告)日：2005-06-16
申请号：US10996435
申请日：2004-11-26
申请人： Kouichi Kizu , Keiji Okada , Masayoshi Yamaguchi
发明人： Kouichi Kizu , Keiji Okada , Masayoshi Yamaguchi
IPC分类号： C08F210/00 , C08F210/06 , C08F210/16 , C08L23/00
CPC分类号： C08F210/16 , C08F210/06 , C08F210/14 , C08F2500/12 , C08F2500/03 , C08F2500/08 , C08F2500/17 , C08F210/08
摘要： (i) A material is developed which modifies the rigidity, tensile elongation at break and impact resistance of resins such as a polypropylene resin when used as a modifier. The invention relates to an ethylene type ternary copolymer (A) comprising (i) an ethylene, propylene or 1-butene and a higher α-olefin having 6 to 20 carbon atoms, wherein the content of ethylene is 70 to 89 mol %, the content of propylene or 1-butene is 10 to 22 mol % and the content of a higher α-olefin having 6 to 20 carbon atoms is 1 to 11 mol % and the molar ratio of the higher-olefin having 6 to 20 carbon atoms to the structural units except for ethylene (either propylene or 1-butene and the higher α-olefin having 6 to 20 carbon atoms) is 1/10 to 5/10 and the ethylene type ternary copolymer has a density of 0.857 to 0.885 g/cm3. The invention also relates to (ii) a propylene type resin composition comprising a propylene type polymer (B), the ethylene type ternary copolymer (A) and an inorganic filler (C).
摘要翻译：（i）开发了当用作改性剂时改性树脂如聚丙烯树脂的刚性，断裂拉伸伸长率和耐冲击性的材料。本发明涉及一种乙烯型三元共聚物（A），其包含（i）乙烯，丙烯或1-丁烯和具有6至20个碳原子的较高级α-烯烃，其中乙烯的含量为70至89摩尔％，丙烯或1-丁烯的含量为10〜22摩尔％，碳原子数6〜20的高级α-烯烃的含量为1〜11摩尔％，碳原子数为6〜20的高级烯烃的摩尔比为乙烯（丙烯或1-丁烯和碳原子数6〜20的高级α-烯烃）以外的结构单元为1/10〜5/10，乙烯型三元共聚物的密度为0.857〜0.885g / cm 3 ^{3 。本发明还涉及（ii）包含丙烯类聚合物（B），乙烯型三元共聚物（A）和无机填料（C）的丙烯类树脂组合物。}

4. 发明授权

US09301945B2 Methods for treating inflammatory conditions and states, and cancers by antagonizing NF-κB activation 有权
标题翻译：通过拮抗NF-κB活化来治疗炎症状态和状态以及癌症的方法
公开(公告)号：US09301945B2
公开(公告)日：2016-04-05
申请号：US14234033
申请日：2012-07-19
申请人： M. Neale Weitzmann , Masayoshi Yamaguchi
发明人： M. Neale Weitzmann , Masayoshi Yamaguchi
IPC分类号： A61K31/381 , A61K45/06 , A61K33/24
CPC分类号： A61K31/381 , A61K33/24 , A61K45/06
摘要： The disclosure is directed to methods for treating inflammatory conditions and cancers that have misregulated NF-κB. In some embodiments, the disclosure is directed to methods for treating inflammatory conditions, inflammatory states associated with treating HIV and AIDS infections, and cancers that include administering strontium ranelate to a subject diagnosed with or at risk of inflammatory conditions, inflammatory states, and cancers, respectively.
摘要翻译：本公开涉及用于治疗炎症性疾病和已经失调NF-κB的癌症的方法。在一些实施方案中，本公开涉及用于治疗炎性病症，与治疗HIV和AIDS感染相关的炎症状态的癌症，以及包括向被诊断患有或处于炎症状态，炎性状态和癌症风险的受试者施用雷奈酸锶的癌症的方法，分别。

5. 发明授权

US09217078B2 Propylene based resin composition and use thereof 有权
标题翻译：丙烯基树脂组合物及其用途
公开(公告)号：US09217078B2
公开(公告)日：2015-12-22
申请号：US13619135
申请日：2012-09-14
申请人： Hiroshi Hoya , Kiminori Noda , Norihide Inoue , Hiroshi Uehara , Eiji Shiba , Masayoshi Yamaguchi , Manabu Kawamoto , Akira Yamashita
发明人： Hiroshi Hoya , Kiminori Noda , Norihide Inoue , Hiroshi Uehara , Eiji Shiba , Masayoshi Yamaguchi , Manabu Kawamoto , Akira Yamashita
IPC分类号： B32B27/08 , B32B7/02 , C08L23/12 , C08L23/08 , C08L23/10 , C08L23/14 , C08L23/16 , C08L53/02 , H01L31/048
CPC分类号： C08J9/0061 , A43B13/04 , A43B13/12 , A43B17/006 , B32B5/18 , B32B9/025 , B32B25/00 , B32B27/065 , B32B27/32 , B32B27/40 , B32B2250/02 , B32B2437/02 , C08J5/18 , C08J2323/08 , C08J2323/12 , C08J2323/14 , C08J2423/12 , C08J2423/14 , C08L23/0815 , C08L23/10 , C08L23/12 , C08L23/14 , C08L23/142 , C08L23/16 , C08L23/26 , C08L25/04 , C08L53/02 , C08L2205/02 , H01L31/0481 , Y10T428/1397 , Y10T428/24942 , Y10T428/31692 , Y10T428/31913 , Y10T428/31938 , Y10T442/60 , C08L2666/06 , C08L2666/02 , C08L2666/24
摘要： Means for Solving the ProblemsThe thermoplastic resin composition (X1) of the present invention comprises (A1), (B1), (C1), and optionally (D1) below: 1 to 90 wt % of an isotactic polypropylene (A1); 9 to 98 wt % of a propylene/ethylene/α-olefin copolymer (B1) containing 45 to 89 mol % of propylene-derived structural units, 10 to 25 mol % of ethylene-derived structural units, and optionally, 0 to 30 mol % of C4-C20α-olefin-derived structural units (a1); 1 to 80 wt % of a styrene-based elastomer (C1); and 0 to 70 wt % of an ethylene/α-olefin copolymer (D1) whose density is in the range of 0.850 to 0.910 g/cm3, wherein (A1)+(B1)+(C1)+(D1)=100 wt %.
摘要翻译：解决问题的手段本发明的热塑性树脂组合物（X1）包含（A1），（B1），（C1）和任选（D1）：1〜90重量％的全同立构聚丙烯（A1）; 9〜98重量％的丙烯 - 乙烯/α-烯烃共聚物（B1），含有45〜89摩尔％的丙烯衍生的结构单元，10〜25摩尔％的来自乙烯的结构单元，任选的0〜30摩尔％的C 4 -C 20α-烯烃衍生的结构单元（a1）; 1〜80重量％的苯乙烯系弹性体（C1）; 和0〜70重量％的密度为0.850〜0.910g / cm 3的乙烯/α-烯烃共聚物（D1），其中（A1）+（B1）+（C1）+（D1）= 100重量％％。

6. 发明申请

US20140163093A1 METHODS FOR TREATING INFLAMATORY CONDITIONS AND STATES, AND CANCERS BY ANTAGONIZING NF-kB ACTIVATION 审中-公开
标题翻译：通过拮抗NF-kB激活治疗炎症病症和状况的方法和癌症
公开(公告)号：US20140163093A1
公开(公告)日：2014-06-12
申请号：US14234033
申请日：2012-07-19
申请人： M. Neale Weitzmann , Masayoshi Yamaguchi
发明人： M. Neale Weitzmann , Masayoshi Yamaguchi
IPC分类号： A61K31/381 , A61K45/06
CPC分类号： A61K31/381 , A61K33/24 , A61K45/06
摘要： The disclosure is directed to methods for treating inflammatory conditions and cancers that have misregulated NF-κB. In some embodiments, the disclosure is directed to methods for treating inflammatory conditions, inflammatory states associated with treating HIV and AIDS infections, and cancers that include administering strontium ranelate to a subject diagnosed with or at risk of inflammatory conditions, inflammatory states, and cancers, respectively.
摘要翻译：本公开涉及用于治疗炎症性疾病和已经失调NF-κB的癌症的方法。在一些实施方案中，本公开涉及用于治疗炎性病症，与治疗HIV和AIDS感染相关的炎症状态的癌症，以及包括向被诊断患有或处于炎症状态，炎性状态和癌症风险的受试者施用雷奈酸锶的癌症的方法，分别。

7. 发明申请

US20130011596A1 PROPYLENE BASED RESIN COMPOSITION AND USE THEREOF 有权
标题翻译：基于丙烯的树脂组合物及其用途
公开(公告)号：US20130011596A1
公开(公告)日：2013-01-10
申请号：US13619001
申请日：2012-09-14
申请人： Hiroshi HOYA , Kiminori Noda , Norihide Inoue , Hiroshi Uehara , Eiji Shiba , Masayoshi Yamaguchi , Manabu Kawamoto , Akira Yamashita
发明人： Hiroshi HOYA , Kiminori Noda , Norihide Inoue , Hiroshi Uehara , Eiji Shiba , Masayoshi Yamaguchi , Manabu Kawamoto , Akira Yamashita
IPC分类号： C08L23/14 , B32B1/08 , C08L23/12 , C08L23/20 , C08L53/00
CPC分类号： C08J9/0061 , A43B13/04 , A43B13/12 , A43B17/006 , B32B5/18 , B32B9/025 , B32B25/00 , B32B27/065 , B32B27/32 , B32B27/40 , B32B2250/02 , B32B2437/02 , C08J5/18 , C08J2323/08 , C08J2323/12 , C08J2323/14 , C08J2423/12 , C08J2423/14 , C08L23/0815 , C08L23/10 , C08L23/12 , C08L23/14 , C08L23/142 , C08L23/16 , C08L23/26 , C08L25/04 , C08L53/02 , C08L2205/02 , H01L31/0481 , Y10T428/1397 , Y10T428/24942 , Y10T428/31692 , Y10T428/31913 , Y10T428/31938 , Y10T442/60 , C08L2666/06 , C08L2666/02 , C08L2666/24
摘要： Means for Solving the ProblemsThe thermoplastic resin composition (X1) of the present invention comprises (A1), (B1), (C1), and optionally (D1) below: 1 to 90 wt % of an isotactic polypropylene (A1); 9 to 98 wt % of a propylene/ethylene/α-olefin copolymer (B1) containing 45 to 89 mol % of propylene-derived structural units, 10 to 25 mol % of ethylene-derived structural units, and optionally, 0 to 30 mol % of C4-C20 α-olefin-derived structural units (a1); 1 to 80 wt % of a styrene-based elastomer (C1); and 0 to 70 wt % of an ethylene/α-olefin copolymer (D1) whose density is in the range of 0.850 to 0.910 g/cm3, wherein (A1)+(B1)+(C1)+(D1)=100 wt %.
摘要翻译：解决问题的手段本发明的热塑性树脂组合物（X1）包含（A1），（B1），（C1）和任选（D1）：1〜90重量％的全同立构聚丙烯（A1）; 9〜98重量％的丙烯 - 乙烯/α-烯烃共聚物（B1），含有45〜89摩尔％的丙烯衍生的结构单元，10〜25摩尔％的来自乙烯的结构单元，任选的0〜30摩尔％的C 4 -C 20α-烯烃衍生的结构单元（a1）; 1〜80重量％的苯乙烯系弹性体（C1）; 和0〜70重量％的密度为0.850〜0.910g / cm 3的乙烯/α-烯烃共聚物（D1），其中（A1）+（B1）+（C1）+（D1）= 100重量％％。

8. 发明授权

US08148431B2 Osteogenesis promoter containing β-cryptoxanthin as the active ingredient 有权
标题翻译：含骨质疏松促进剂含有黄曲霉毒素作为活性成分
公开(公告)号：US08148431B2
公开(公告)日：2012-04-03
申请号：US10532775
申请日：2003-10-03
申请人： Masayoshi Yamaguchi
发明人： Masayoshi Yamaguchi
IPC分类号： A61K31/07
CPC分类号： A61K31/07 , A23K20/174 , A23K20/179 , A23L33/105 , A61K31/045
摘要： It is intended to provide an osteogenesis promoter having a remarkable effect of positively promoting osteogenesis and thus preventing/treating bone diseases; a preventive/a remedy for bone diseases such as osteoporosis having both of an osteogenesis-promoting effect and a bone resorption-inhibiting effect; and a method of screening an active ingredient for preventing/treating bone diseases by using a compound having both of an osteogenesis-promoting effect and a bone resorption-inhibiting effect as a lead compound. It is confirmed that beta-cryptoxanthin, which occurs in a large amount in peel and sarcocarp of satsuma orange, has an osteogenesis-promoting effect and a therapeutic effect on bone disease. Thus, beta-cryptoxanthin or its composition is used as an osteogenesis promoter, a preventive/a remedy for bone diseases, a functional food or a food material for preventing/treating bone diseases and a feed composition.
摘要翻译：本发明提供一种成骨促进剂，其具有积极促进成骨，从而预防/治疗骨病的显着效果; 骨质疏松症等骨疾病的预防/补救措施，具有成骨促进作用和骨吸收抑制作用; 以及通过使用具有成骨促进作用和骨吸收抑制作用两者的化合物作为前导化合物来筛选用于预防/治疗骨疾病的活性成分的方法。可以确认，在沙粒的果皮和果肉中大量发生的β-隐黄质具有成骨促进作用和对骨病的治疗作用。因此，β-隐黄质或其组合物用作成骨促进剂，用于骨疾病的预防/治疗，功能性食品或用于预防/治疗骨疾病的食物材料和饲料组合物。

9. 发明申请

US20100130662A1 CROSSLINKED MATERIAL OF PROPYLENE RESIN COMPOSITION, A PROCESS FOR PRODUCING THE CROSSLINKED MATERIAL AND CROSSLINKED MOLDED ARTICLE FORMED FROM THE CROSSLINKED MATERIAL 有权
标题翻译：丙烯类树脂组合物的交联材料，生产从交联材料形成的交联材料和交联成型品的方法
公开(公告)号：US20100130662A1
公开(公告)日：2010-05-27
申请号：US12451242
申请日：2008-04-23
申请人： Hiroshi Uehara , Kiminori Noda , Masayoshi Yamaguchi
发明人： Hiroshi Uehara , Kiminori Noda , Masayoshi Yamaguchi
IPC分类号： C08K3/26 , C08L23/12 , C08F110/06
CPC分类号： C08J3/24 , C08J7/123 , C08J2323/10 , C08J2423/10 , C08K5/0025 , C08K5/34924 , C08L23/10 , C08L2205/02 , H01B3/441 , C08L2666/06
摘要： The crosslinked material of the present invention is obtainable by crosslinking a propylene resin composition through irradiation with an ionizing radiation wherein the propylene resin composition comprises 100 parts by mass of a propylene resin comprising 15 to 99% by mass of a propylene polymer (A) having a melting point, as measured by a differential scanning calorimeter (DSC), of 120 to 170° C., and 1 to 85% by mass of propylene polymer (B) having a melting point, as measured by a differential scanning calorimeter (DSC), of below 120° C. or not observed (provided that the total of the components (A) and (B) is 100% by mass), and 0.1 to 5 parts by mass of a crosslinking assistant (C). The production process of the crosslinked material of the present invention comprises a step of molding the propylene resin composition into a molded form, and a step of crosslinking the molded form through irradiation with an ionizing radiation. The crosslinked molded article of the present invention is formed from the crosslinked material.
摘要翻译：本发明的交联材料可以通过用电离辐射照射使丙烯树脂组合物交联而获得，其中丙烯树脂组合物包含100质量份含有15至99质量％的丙烯聚合物（A）的丙烯树脂，其具有通过差示扫描量热计（DSC）测定的熔点为120〜170℃，1〜85质量％的通过差示扫描量热计（DSC）测定的熔点的丙烯聚合物（B）），低于120℃或未观察到（组分（A）和（B）的总量为100质量％）和0.1〜5质量份交联助剂（C）。本发明的交联材料的制造方法包括将丙烯类树脂组合物成型为成型体的工序，以及通过电离辐射照射使成型体交联的工序。本发明的交联成型体由交联材料形成。

10. 发明申请

US20080056581A1 Database management program, database management apparatus and database management method 有权
标题翻译：数据库管理程序，数据库管理装置和数据库管理方法
公开(公告)号：US20080056581A1
公开(公告)日：2008-03-06
申请号：US11892650
申请日：2007-08-24
申请人： Masayoshi Yamaguchi , Terutoshi Taguchi
发明人： Masayoshi Yamaguchi , Terutoshi Taguchi
IPC分类号： G06K9/46 , G06F17/30
CPC分类号： G06F17/30259 , G06K9/6211
摘要： A database management program, a database management apparatus and a database management method can determine the sameness of shape data at high speed. The program causes a computer to execute a first edge line acquisition step that acquires the edge lines of the first shape data, an information registration step that generates information showing the characteristics of the edge lines acquired by the first edge line acquisition step as first edge line characteristic information, associates the first edge line characteristic information with the first shape data and registers them in a database, a second edge line acquisition step that acquires the edge lines of the second shape data showing the requirements of retrieval, an information generation step that generates edge line characteristic information of the edge lines acquired by the second edge line acquisition step as second edge line characteristic information and a retrieval step that retrieves the third shape data that is the part of the first shape data that agrees with the second shape data according to the first edge line characteristic information and the second edge line characteristic information.
摘要翻译：数据库管理程序，数据库管理装置和数据库管理方法可以高速确定形状数据的同一性。该程序使计算机执行获取第一形状数据的边缘线的第一边缘线获取步骤，产生表示通过第一边缘线获取步骤获取的边缘线的特性的信息作为第一边缘线的信息登记步骤特征信息，将第一边缘线特征信息与第一形状数据相关联并将它们登记在数据库中;第二边缘线获取步骤，获取表示检索要求的第二形状数据的边缘线;信息生成步骤，生成由第二边缘线获取步骤获取的边缘线的边缘线特性信息作为第二边缘线特征信息;以及检索步骤，检索作为与第二形状数据相符合的第一形状数据的第三形状数据，根据第一边缘线特征信息和第二边缘线c 特征信息。

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