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1. 发明申请

US20070004700A1 2-Thioethenyl substituted carbapenem derivatives 失效
标题翻译： 2-噻吩基取代的碳青霉烯衍生物
公开(公告)号：US20070004700A1
公开(公告)日：2007-01-04
申请号：US11401892
申请日：2006-04-12
申请人： Takahisa Maruyama , Yuko Kano , Takashi Ando , Toshiro Sasaki , Takehiko Sawabe , Nobuyoshi Baba , Hiromi Takata , Hisashi Suzuki , Kazuhiro Aihara , Toshiki Fujita
发明人： Takahisa Maruyama , Yuko Kano , Takashi Ando , Toshiro Sasaki , Takehiko Sawabe , Nobuyoshi Baba , Hiromi Takata , Hisashi Suzuki , Kazuhiro Aihara , Toshiki Fujita
IPC分类号： A61K31/407 , C07D487/04
CPC分类号： C07D487/04
摘要： [Objective] An objective of the present invention is to provide compounds that are effective against various resistant bacteria which cause current clinical problems, for example, pneumococci including penicillin resistant Streptococcus pneumoneae (PRSP), Haemophilus influenzae including bata-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae (BLNAR), and Moraxella (Branhamella) catarrhalis. [Structure] The present invention provides 2-ethenylthio-based carbapenem derivatives represented by the formula (I) or pharmaceutically acceptable salts thereof that are effective, for example, against pneumococci including penicillin resistant Streptococcus pneumoneae (PRSP), Haemophilus influenzae including beta-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae (BLNAR), and Moraxella (Branhamella) catarrhalis:
摘要翻译： [目的]本发明的目的是提供对于引起目前临床问题的各种抗性细菌有效的化合物，例如包括耐青霉素的肺炎链球菌（PRSP），流感嗜血杆菌，包括不产生氨苄青霉素的bata-内酰胺酶的肺炎球菌流感嗜血杆菌（BLNAR）和莫拉氏菌（布拉汉氏菌）卡他氏菌。 [结构]本发明提供了式（I）表示的2-乙烯基硫代碳青霉烯衍生物或其药学上可接受的盐，其可有效地例如针对包括耐青霉素的肺炎链球菌（PRSP）在内的肺炎球菌，包括β-内酰胺酶的流感嗜血杆菌 - 非生产氨苄青霉素耐药性流感嗜血杆菌（BLNAR）和莫拉氏菌（Branhamella）卡他性：

2. 发明授权

US07687490B2 2-thioethenyl substituted carbapenem derivatives 失效
标题翻译： 2-硫代乙烯基取代的碳青霉烯衍生物
公开(公告)号：US07687490B2
公开(公告)日：2010-03-30
申请号：US11401892
申请日：2006-04-12
申请人： Takahisa Maruyama , Yuko Kano , Takashi Ando , Takehiko Sawabe , Nobuyoshi Baba , Hiromi Takata , Hisashi Suzuki , Kazuhiro Aihara , Toshiki Fujita
发明人： Takahisa Maruyama , Yuko Kano , Takashi Ando , Takehiko Sawabe , Nobuyoshi Baba , Hiromi Takata , Hisashi Suzuki , Kazuhiro Aihara , Toshiki Fujita
IPC分类号： C07D477/20 , A61K31/426 , A61K31/454 , A61P31/04 , C07D277/56 , C07D277/26 , C07D277/30 , C07D277/40 , C07D417/06
CPC分类号： C07D487/04
摘要： An objective of the present invention is to provide compounds that are effective against various resistant bacteria which cause current clinical problems, for example, pneumococci including penicillin resistant Streptococcus pneumoneae (PRSP), Haemophilus influenzae including bata-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae (BLNAR), and Moraxella (Branhamella) catarrhalis.The present invention provides 2-ethenylthio-based carbapenem derivatives represented by the formula (I) or pharmaceutically acceptable salts thereof that are effective, for example, against pneumococci including penicillin resistant Streptococcus pneumoneae (PRSP), Haemophilus influenzae including beta-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae (BLNAR), and Moraxella (Branhamella) catarrhalis:
摘要翻译：本发明的目的是提供对于引起当前临床问题的各种耐药性细菌有效的化合物，例如包括耐青霉素的肺炎链球菌（PRSP），流感嗜血杆菌（Haemophilus influenzae），包括不含巴生酵母的氨苄青霉素抗性流感嗜血杆菌 BLNAR）和莫拉氏菌（Branhamella）卡他氏菌。本发明提供了由式（I）表示的2-乙烯基硫代碳青霉烯衍生物或其药学上可接受的盐，其可有效地例如针对包括耐青霉素的肺炎链球菌（PRSP）在内的肺炎球菌，流感嗜血杆菌，包括β-内酰胺酶非生产氨苄青霉素耐药性流感嗜血杆菌（BLNAR）和莫拉氏菌（Branhamella）卡他性：

3. 发明授权

US08344154B2 2-thioethenyl substituted carbapenem derivatives 失效
标题翻译： 2-硫代乙烯基取代的碳青霉烯衍生物
公开(公告)号：US08344154B2
公开(公告)日：2013-01-01
申请号：US12656606
申请日：2010-02-04
申请人： Takahisa Maruyama , Yuko Kano , Takashi Ando , Toshiro Sasaki , Kazuhiro Aihara , Toshiki Fujita
发明人： Takahisa Maruyama , Yuko Kano , Takashi Ando , Toshiro Sasaki , Kazuhiro Aihara , Toshiki Fujita
IPC分类号： C07D277/24 , C07D277/26
CPC分类号： C07D487/04
摘要： 2-Ethenylthio-type carbapenem derivatives of formula (I) or pharmaceutically acceptable salts thereof are provided. The compounds according to the present invention have potent antimicrobial activity and a wide antimicrobial spectrum against pneumococci including penicillin resistant Streptococcus pneumoniae (PRSP), Haemophilus influenzae including β-lactamase-negative, ampicillin-resistant Haemophilus influenzae (BLNAR), and Moraxella (Branhamella) catarrhalis.
摘要翻译：提供式（I）的2-乙烯基硫代碳代青霉烯衍生物或其药学上可接受的盐。根据本发明的化合物具有有效的抗微生物活性和抗肺炎球菌的广谱抗菌谱，包括耐青霉素肺炎链球菌（PRSP），流感嗜血杆菌，包括β-内酰胺酶阴性，氨苄青霉素抗性流感嗜血杆菌（BLNAR）和莫拉氏菌）卡他氏菌

4. 发明申请

US20100145063A1 2- thioethenyl substituted carbapenem derivatives 失效
标题翻译： 2-硫代乙烯基取代的碳青霉烯衍生物
公开(公告)号：US20100145063A1
公开(公告)日：2010-06-10
申请号：US12656606
申请日：2010-02-04
申请人： Takahisa Maruyama , Yuko Kano , Takashi Ando , Toshiro Sasaki , Kazuhiro Aihara , Toshiki Fujita
发明人： Takahisa Maruyama , Yuko Kano , Takashi Ando , Toshiro Sasaki , Kazuhiro Aihara , Toshiki Fujita
IPC分类号： C07D277/34 , C07D417/02
CPC分类号： C07D487/04
摘要： 2-Ethenylthio-type carbapenem derivatives of formula (I) or pharmaceutically acceptable salts thereof are provided. The compounds according to the present invention have potent antimicrobial activity and a wide antimicrobial spectrum against pneumococci including penicillin resistant Streptococcus pneumoniae (PRSP), Haemophilus influenzae including β-lactamase-negative, ampicillin-resistant Haemophilus influenzae (BLNAR), and Moraxella (Branhamella) catarrhalis.
摘要翻译：提供式（I）的2-乙烯基硫代碳代青霉烯衍生物或其药学上可接受的盐。根据本发明的化合物具有有效的抗微生物活性和抗肺炎球菌的广谱抗菌谱，包括耐青霉素肺炎链球菌（PRSP），流感嗜血杆菌，包括β-内酰胺酶阴性，氨苄青霉素抗性流感嗜血杆菌（BLNAR）和莫拉氏菌）卡他氏菌

5. 发明授权

US4955227A Apparatus for inspecting glass bottles 失效
标题翻译：检查玻璃瓶的装置
公开(公告)号：US4955227A
公开(公告)日：1990-09-11
申请号：US209952
申请日：1988-05-25
申请人： Toshiki Fujita , Hirokazu Kimura , Yoshihiro Yamato
发明人： Toshiki Fujita , Hirokazu Kimura , Yoshihiro Yamato
IPC分类号： B07C5/12 , B07C5/34 , B07C5/36 , G01B5/00 , G01B5/02 , G01B5/08 , G01B5/12 , G01B5/24 , G01N19/08
CPC分类号： G01B5/24 , B07C5/124 , B07C5/34 , B07C5/36 , G01B5/08
摘要： An apparatus for inspecting glass bottles generally comprises an operation table, an annular conveyor passage onto which glass bottles to be inspected are conveyed one-by-one and on which the bottles are moved slidably, and a turn table coaxially disposed inside the annular conveyor passage. A plurality of guide members are circumferentially mounted on the peripheral surface of the turn table, and a plurality of bottle inspecting stations are disposed circumferentially and spaced equally therearound. The inspecting stations include a down sealing surface measuring station for measuring the down sealing surface of the lip portion of each bottle, an outer diameter and perpendicularly measuring station for measuring outer diameters of the various portions of each bottle and an inner diameter measuring station for measuring the inner diameter of the lip opening. The bottles inspected or measured are conveyed out of the conveying passage and selectively divided into defective bottles and satisfactory bottles.
摘要翻译：用于检查玻璃瓶的装置通常包括操作台（1），环形输送通道，待检查的玻璃瓶一个接一个地输送到其上，并且瓶子可滑动地移动到其上并且同时旋转的转台设置在环形输送通道内。多个引导构件（6）周向地安装在转台的周面上，并且多个瓶检查站（A-F）周向地设置在其周围。检查站包括用于测量每个瓶子的唇缘部分的向下密封表面的下封面测量站，用于测量每个瓶子的各个部分的外径的外径和垂直度测量站以及用于测量的内径测量站唇口的内径。检查或测量的瓶子被输送出输送通道，并选择性地分成有缺陷的瓶子和令人满意的瓶子。

6. 发明授权

US5930726A Mobile communication without call interruption during transition between outdoor and indoor modes 失效
标题翻译：移动通信在室外和室外模式之间转换期间无呼叫中断
公开(公告)号：US5930726A
公开(公告)日：1999-07-27
申请号：US784925
申请日：1997-01-16
申请人： Toshiki Fujita
发明人： Toshiki Fujita
IPC分类号： H04B7/26 , H04B7/005 , H04B7/15 , H04W16/26 , H04W52/50 , H04B1/00
CPC分类号： H04W16/26 , H04W52/50
摘要： A mobile communication system having a base station and a mobile station, provided with indoor and outdoor antennas in different locations of a building structure that substantially prevents penetration of electromagnetic radiation. A communication unit is connected between the indoor and outdoor antennas. The communication unit is arranged to detect a signal received at the indoor antenna from the mobile station while the mobile station is communicating with the base station, determines that the mobile station is entering the structure when the detected signal exceeds a predetermined reference level and establishes a radio link between the outdoor antenna and the base station and a circuit between the indoor and outdoor antennas and commands the mobile station to establish a radio link to the indoor antenna. The radio link established between the mobile station and the indoor antenna uses forward and reverse channels that avoid interference with other mobile stations.
摘要翻译：一种具有基站和移动台的移动通信系统，其在建筑物结构的不同位置设置有室内和室外天线，其基本上防止电磁辐射的穿透。通信单元连接在室内和室外天线之间。通信单元被配置为当移动台正在与基站进行通信时，从移动台检测在室内天线处接收到的信号，当检测到的信号超过预定参考电平时确定移动台正在进入结构，并建立室外天线与基站之间的无线电链路以及室内和室外天线之间的电路，并命令移动台建立到室内天线的无线电链路。建立在移动台和室内天线之间的无线电链路使用避免与其他移动台干扰的前向和反向信道。

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