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1. 发明授权

US07977331B1 Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor 有权
标题翻译：四环稠合杂环化合物及其作为HCV聚合酶抑制剂的用途
公开(公告)号：US07977331B1
公开(公告)日：2011-07-12
申请号：US11962622
申请日：2007-12-21
申请人： Takahiro Oka , Kazutaka Ikegashira , Shintaro Hirashima , Hiroshi Yamanaka , Satoru Noji , Yasushi Niwa , Yoko Matsumoto , Toshihiro Sato , Izuru Ando , Yukihiro Nomura
发明人： Takahiro Oka , Kazutaka Ikegashira , Shintaro Hirashima , Hiroshi Yamanaka , Satoru Noji , Yasushi Niwa , Yoko Matsumoto , Toshihiro Sato , Izuru Ando , Yukihiro Nomura
IPC分类号： A61K31/53 , A61K31/495 , A61K31/519 , A61K31/44 , A61K31/415 , A61K31/40 , C07D253/00 , C07D487/00 , C07D239/02 , C07D471/02 , C07D209/80
CPC分类号： C07D513/04 , C07D487/04 , C07D487/14 , C07D498/04 , C07D498/14
摘要： The present invention relates to a tetracyclic fused heterocyclic compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable a salt thereof, and a hepatitis C virus (HCV) polymerase inhibitor and a therapeutic agent for hepatitis C containing this compound. The compound of the present invention shows an anti-HCV activity based on the HCV polymerase inhibitory activity, and useful as an agent for the prophylaxis or treatment of hepatitis C.
摘要翻译：本发明涉及由下式[I]表示的四环稠合杂环化合物，其中各符号如说明书中所定义，或其药学上可接受的盐，丙型肝炎病毒（HCV）聚合酶抑制剂和治疗剂含有该化合物的丙型肝炎。本发明化合物基于HCV聚合酶抑制活性显示抗HCV活性，可用作预防或治疗丙型肝炎的药剂。

2. 发明申请

US20120070409A1 TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR 审中-公开
标题翻译：四氢呋喃杂交化合物及其作为HCV聚合酶抑制剂的用途
公开(公告)号：US20120070409A1
公开(公告)日：2012-03-22
申请号：US13020621
申请日：2011-02-03
申请人： Takahiro Oka , Kazutaka Ikegashira , Shintaro Hirashima , Hiroshi Yamanaka , Satoru Noji , Yasushi Niwa , Yoko Matsumoto , Toshihiro Sato , Izuru Ando , Yukihiro Nomura
发明人： Takahiro Oka , Kazutaka Ikegashira , Shintaro Hirashima , Hiroshi Yamanaka , Satoru Noji , Yasushi Niwa , Yoko Matsumoto , Toshihiro Sato , Izuru Ando , Yukihiro Nomura
IPC分类号： A61K31/553 , C07D487/04 , C07D498/04 , C07D513/04 , A61K31/5365 , A61K31/55 , A61K31/407 , A61K31/542 , A61P1/16 , A61K38/21 , A61P31/14 , A61K31/554 , C07D498/14 , C07D471/14 , C07D471/04 , A61K31/4745 , C07D519/00 , A61K31/5517
CPC分类号： C07D513/04 , C07D487/04 , C07D487/14 , C07D498/04 , C07D498/14
摘要： The present invention relates to a tetracyclic fused heterocyclic compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable a salt thereof, and a hepatitis C virus (HCV) polymerase inhibitor and a therapeutic agent for hepatitis C containing this compound. The compound of the present invention shows an anti-HCV activity based on the HCV polymerase inhibitory activity, and useful as an agent for the prophylaxis or treatment of hepatitis C.
摘要翻译：本发明涉及由下式[I]表示的四环稠合杂环化合物，其中各符号如说明书中所定义，或其药学上可接受的盐，丙型肝炎病毒（HCV）聚合酶抑制剂和治疗剂含有该化合物的丙型肝炎。本发明化合物基于HCV聚合酶抑制活性显示抗HCV活性，可用作预防或治疗丙型肝炎的药剂。

3. 发明申请

US20070049593A1 Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor 审中-公开
标题翻译：四环稠合杂环化合物及其作为HCV聚合酶抑制剂的用途
公开(公告)号：US20070049593A1
公开(公告)日：2007-03-01
申请号：US11064319
申请日：2005-02-23
申请人： Takahiro Oka , Kazutaka Ikegashira , Shintaro Hirashima , Hiroshi Yamanaka , Satoru Noji , Yasushi Niwa , Yoko Matsumoto , Toshihiro Sato , Izuru Ando , Yukihiro Nomura
发明人： Takahiro Oka , Kazutaka Ikegashira , Shintaro Hirashima , Hiroshi Yamanaka , Satoru Noji , Yasushi Niwa , Yoko Matsumoto , Toshihiro Sato , Izuru Ando , Yukihiro Nomura
IPC分类号： C07D471/02 , A61K31/53 , A61K31/519 , A61K31/498 , A61K31/503 , A61K31/4745
CPC分类号： C07D513/04 , C07D487/04 , C07D487/14 , C07D498/04 , C07D498/14
摘要： The present invention relates to a tetracyclic fused heterocyclic compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable a salt thereof, and a hepatitis C virus (HCV) polymerase inhibitor and a therapeutic agent for hepatitis C containing this compound. The compound of the present invention shows an anti-HCV activity based on the HCV polymerase inhibitory activity, and useful as an agent for the prophylaxis or treatment of hepatitis C.
摘要翻译：本发明涉及由下式[I]表示的四环稠合杂环化合物，其中各符号如说明书中所定义，或其药学上可接受的盐，丙型肝炎病毒（HCV）聚合酶抑制剂和治疗剂含有该化合物的丙型肝炎。本发明化合物基于HCV聚合酶抑制活性显示抗HCV活性，可用作预防或治疗丙型肝炎的药剂。

4. 发明申请

US20120020920A1 5-5-MEMBERED FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR 审中-公开
标题翻译： 5-5-共聚合的杂环化合物及其作为HCV聚合酶抑制剂的用途
公开(公告)号：US20120020920A1
公开(公告)日：2012-01-26
申请号：US13034306
申请日：2011-02-24
申请人： Ryo Mizojiri , Shintaro Hirashima , Takahiro Oka , Kenta Aoki , Satoru Noji , Izuru Ando , Toshihiro Sato , Yasushi Niwa
发明人： Ryo Mizojiri , Shintaro Hirashima , Takahiro Oka , Kenta Aoki , Satoru Noji , Izuru Ando , Toshihiro Sato , Yasushi Niwa
IPC分类号： A61K38/21 , A61K31/4188 , A61K31/407 , A61P1/16 , A61K31/496 , A61K31/454 , A61K31/4545 , A61P31/14 , C07D495/04 , A61K31/5377
CPC分类号： C07D495/04
摘要： The present invention relates to a fused ring compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable a salt thereof, and a hepatitis C virus (HCV) polymerase inhibitor and a therapeutic agent for hepatitis C containing this compound. The compound of the present invention shows an anti-HCV activity based on the HCV polymerase inhibitory activity, and useful as an agent for the prophylaxis or treatment of hepatitis C.
摘要翻译：本发明涉及由下式[I]表示的稠环化合物，其中各符号如说明书中所定义，或其药学上可接受的盐，丙型肝炎病毒（HCV）聚合酶抑制剂和治疗剂含有该化合物的丙型肝炎。本发明化合物基于HCV聚合酶抑制活性显示抗HCV活性，可用作预防或治疗丙型肝炎的药剂。

5. 发明申请

US20090036444A1 5-5-Membered fused heterocyclic compound and use thereof as HCV polymerase inhibitor 审中-公开
标题翻译： 5-5-稠合杂环化合物及其作为HCV聚合酶抑制剂的用途
公开(公告)号：US20090036444A1
公开(公告)日：2009-02-05
申请号：US11436375
申请日：2006-05-18
申请人： Ryo Mizojiri , Shintaro Hirashima , Takahiro Oka , Kenta Aoki , Satoru Noji , Izuru Ando , Toshihiro Sato , Yasushi Niwa
发明人： Ryo Mizojiri , Shintaro Hirashima , Takahiro Oka , Kenta Aoki , Satoru Noji , Izuru Ando , Toshihiro Sato , Yasushi Niwa
IPC分类号： A61K31/5377 , C07D235/02 , A61K31/4188 , C07D495/02 , A61K31/496 , A61K31/454 , A61P31/12 , A61K31/4545 , C07D211/00 , C07D241/02 , A61K31/407 , C07D295/00
CPC分类号： C07D495/04
摘要： The present invention relates to a fused ring compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable a salt thereof, and a hepatitis C virus (HCV) polymerase inhibitor and a therapeutic agent for hepatitis C containing this compound. The compound of the present invention shows an anti-HCV activity based on the HCV polymerase inhibitory activity, and useful as an agent for the prophylaxis or treatment of hepatitis C.
摘要翻译：本发明涉及由下式[I]表示的稠环化合物，其中每个符号如说明书中所定义，或其药学上可接受的盐，丙型肝炎病毒（HCV）聚合酶抑制剂和治疗剂含有该化合物的丙型肝炎。本发明化合物基于HCV聚合酶抑制活性显示抗HCV活性，可用作预防或治疗丙型肝炎的药剂。

6. 发明申请

US20060167246A1 Thienopyrrole compound and use thereof as HCV polymerase inhibitor 失效
标题翻译：噻吩并吡咯化合物及其作为HCV聚合酶抑制剂的用途
公开(公告)号：US20060167246A1
公开(公告)日：2006-07-27
申请号：US11271136
申请日：2005-11-10
申请人： Ryo Mizojiri , Takahiro Oka , Kenta Aoki , Satoru Noji , Yoko Matsumoto , Toshihiro Sato , Izuru Ando , Yasushi Niwa
发明人： Ryo Mizojiri , Takahiro Oka , Kenta Aoki , Satoru Noji , Yoko Matsumoto , Toshihiro Sato , Izuru Ando , Yasushi Niwa
IPC分类号： A61K31/553 , A61K31/551 , C07D498/14
CPC分类号： C07D498/14 , A61K31/5517 , A61K31/553 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a thienopyrrole compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable a salt thereof, and a hepatitis C virus (HCV) polymerase inhibitor and a therapeutic agent for hepatitis C containing this compound as an active ingredient. The compound of the present invention shows an anti-HCV activity based on the HCV polymerase inhibitory activity, and useful as an agent for the prophylaxis or treatment of hepatitis C.
摘要翻译：本发明涉及由下式[I]表示的噻吩并吡咯化合物，其中各符号如说明书中所定义，或其药学上可接受的盐，丙型肝炎病毒（HCV）聚合酶抑制剂和肝炎治疗剂 C含有该化合物作为活性成分。本发明化合物基于HCV聚合酶抑制活性显示抗HCV活性，可用作预防或治疗丙型肝炎的药剂。

7. 发明授权

US07659263B2 Thienopyrrole compound and use thereof as HCV polymerase inhibitor 失效
标题翻译：噻吩并吡咯化合物及其作为HCV聚合酶抑制剂的用途
公开(公告)号：US07659263B2
公开(公告)日：2010-02-09
申请号：US11271136
申请日：2005-11-10
申请人： Ryo Mizojiri , Takahiro Oka , Kenta Aoki , Satoru Noji , Yoko Matsumoto , Toshihiro Sato , Izuru Ando , Yasushi Niwa
发明人： Ryo Mizojiri , Takahiro Oka , Kenta Aoki , Satoru Noji , Yoko Matsumoto , Toshihiro Sato , Izuru Ando , Yasushi Niwa
IPC分类号： A61P1/16 , A61P31/12 , A61P43/00 , A61K31/553 , A61K31/5517 , C07D498/12 , C07D267/02 , C07D495/14
CPC分类号： C07D498/14 , A61K31/5517 , A61K31/553 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a thienopyrrole compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable a salt thereof, and a hepatitis C virus (HCV) polymerase inhibitor and a therapeutic agent for hepatitis C containing this compound as an active ingredient. The compound of the present invention shows an anti-HCV activity based on the HCV polymerase inhibitory activity, and useful as an agent for the prophylaxis or treatment of hepatitis C.
摘要翻译：本发明涉及由下式[I]表示的噻吩并吡咯化合物，其中各符号如说明书中所定义，或其药学上可接受的盐，丙型肝炎病毒（HCV）聚合酶抑制剂和肝炎治疗剂 C含有该化合物作为活性成分。本发明化合物基于HCV聚合酶抑制活性显示抗HCV活性，可用作预防或治疗丙型肝炎的药剂。

8. 发明授权

US5005359A Air supply control systems for turbocharged internal combustion engines 失效
公开(公告)号：US5005359A
公开(公告)日：1991-04-09
申请号：US324670
申请日：1989-03-17
申请人： Seiji Tashima , Haruo Okimoto , Toshimichi Akagi , Yasushi Niwa
发明人： Seiji Tashima , Haruo Okimoto , Toshimichi Akagi , Yasushi Niwa
IPC分类号： F02B37/007 , F02B37/16 , F02B37/18 , F02D41/00
CPC分类号： F02D41/0007 , F02B37/007 , F02B37/16 , F02B37/18 , Y02T10/144 , Y02T10/42
摘要： An air supply control system for an internal combustion engine comprises a plurality of superchargers including a turbosupercharger, an exhaust cutoff valve operative selectively to open and close an exhaust passage in which a turbine of the turbosupercharger is disposed, an intake air cutoff valve operative selectively to open and close an intake passage in which a blower of the turbosupercharger is disposed, an intake air relief valve operative selectively to open and close a relief passage provided for detouring the blower of the turbosupercharger, an engine operation detector for detecting operating conditions of the engine, a cutoff valve controller operative, in response to the detection output from the engine operation detector, to cause both the exhaust cutoff valve and the intake air cutoff valve to be closed when intake air mass flow fed to the engine is to be relatively small and to cause both the exhaust cutoff valve and the intake air cutoff valve to be open when the intake air mass flow fed to the engine is to be relatively large, and a relief valve controller operative, in response to the detection output from the engine operation detector, to cause the intake air relief valve to be closed at a time point earlier than another time point at which the exhaust cutoff valve is fully opened.

9. 发明授权

US08720421B2 Turbo-charging apparatus for vehicle engine 有权
标题翻译：汽车发动机涡轮增压装置
公开(公告)号：US08720421B2
公开(公告)日：2014-05-13
申请号：US13159628
申请日：2011-06-14
申请人： Yasushi Niwa , Einosuke Suekuni , Atsuhiro Hatabu , Satoshi Nishizaka
发明人： Yasushi Niwa , Einosuke Suekuni , Atsuhiro Hatabu , Satoshi Nishizaka
IPC分类号： F02B33/00 , F02B33/44
CPC分类号： F02B37/013 , F02B29/0406 , F02B37/004 , F02B37/127 , F02B37/183 , F02B39/00 , F02M26/08 , F02M26/10 , F02M26/25 , Y02T10/144
摘要： The disclosure provides a turbo-charging apparatus for a vehicle engine, which includes a first and second turbocharger, an inter-turbine passage connecting a discharging port of a first turbocharger turbine with an introducing port of a second turbocharger turbine, a bypass passage connecting an introducing passage of the first turbocharger turbine with the inter-turbine passage, and a control valve for opening and closing the bypass passage. The inter-turbine passage extends substantially straight from the discharging port of the first turbocharger turbine toward the second turbocharger when viewed from a direction parallel to turbine shafts of the first and second turbochargers, which are arranged substantially parallel to each other, so that the inter-turbine passage connects with an outer circumferential part of the second turbocharger turbine so as to extend in a direction tangent to an outer circumference direction of the second turbocharger turbine.
摘要翻译：本发明提供了一种用于车辆发动机的涡轮增压装置，其包括第一和第二涡轮增压器，将第一涡轮增压器涡轮机的排出口与第二涡轮增压器涡轮机的引入口连接的涡轮机间通道，引入第一涡轮增压器涡轮机与涡轮机间通道的通道，以及用于打开和关闭旁路通道的控制阀。当从与第一和第二涡轮增压器的涡轮轴平行的方向观察时，涡轮间间通道从第一涡轮增压器涡轮机的排出口向第二涡轮增压器基本上直线延伸，第一涡轮增压器和第二涡轮增压器基本上彼此平行布置，涡轮通道与第二涡轮增压器涡轮机的外圆周部分连接，以沿与第二涡轮增压器涡轮机的外周方向相切的方向延伸。

10. 发明授权

US06975052B2 Terminal arrangement of motor and capacitor motor 失效
标题翻译：电机和电容电机的端子排列
公开(公告)号：US06975052B2
公开(公告)日：2005-12-13
申请号：US10921392
申请日：2004-08-19
申请人： Keiji Uchida , Hiroyuki Tanaka , Hitoshi Ishii , Yasushi Niwa , Toshio Kobayashi
发明人： Keiji Uchida , Hiroyuki Tanaka , Hitoshi Ishii , Yasushi Niwa , Toshio Kobayashi
IPC分类号： H02K3/52 , H02K5/22 , H02K7/00
CPC分类号： H02K3/522 , H02K5/225 , H02K2203/03
摘要： A terminal arrangement of a motor has a terminal base formed with a plurality of terminal pins, the terminal base being fixed detachably on a stator iron core of a motor, terminal pins formed on bobbins, connected electrically with windings wound around the bobbins, a printed circuit board arranged on the stator iron core so as to connect electrically the terminal pins formed on the bobbins with the terminal pins formed on the terminal base, and an end bracket arranged so as to cover the printed circuit board. A hole is formed in the stator iron core, and an earth electrode is projected from the terminal base, and inserted into the hole so as to be connected electrically with the stator iron core, the earth electrode being connected electrically to one of the terminal pins formed on the terminal base. A capacitor motor has a motor having a stator iron core, and a phase advancing capacitor fixed detachably on the stator iron core.
摘要翻译：电动机的端子装置具有形成有多个端子销的端子基座，端子基座可拆卸地固定在电动机的定子铁心上，端子销形成在线轴上，与缠绕在线轴上的绕组电连接，印刷布置在定子铁芯上的电路板，以便将形成在线轴上的端子销与形成在端子座上的端子针电连接，以及端盖，以便覆盖印刷电路板。在定子铁芯上形成孔，接地电极从端子基座突出，插入孔内，与定子铁心电连接，接地电极与端子脚之一电连接形成在终端基地。电容器电动机具有定子铁心的电动机和可分离地固定在定子铁芯上的相位前进电容器。

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