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    • 4. 发明专利
    • Method for conditioning intestinal environment by using symbiotics
    • 通过使用符号来调节INTESTINAL环境的方法
    • JP2010126457A
    • 2010-06-10
    • JP2008300365
    • 2008-11-26
    • Taiyo Kagaku Co Ltd太陽化学株式会社
    • ISHIHARA NORIYUKITOKUNAGA MAKOTO
    • A61K36/48A23K1/16A23L1/30A61K31/736A61K35/74A61K36/00A61K36/18A61P1/14
    • PROBLEM TO BE SOLVED: To provide a method for conditioning intestinal environment by using symbiotics, a combination of probiotics and prebiotics. SOLUTION: The method for conditioning intestinal environment comprises oral administration of symbiotics comprising (A) prebiotics and (B) probiotics so as to induce production of butyric acid from lactic acid and sugars inside the intestinal tract and conditioning of the intestinal environment. The (A) prebiotics comprise hydrolyzed endosperm of Cyamopsis tetragonolobus characterized by (1) galactomannan having a weight-average molecular weight of 3-50 kDa obtained by gel filtration on high-performance liquid chromatography using pullulan as a molecular marker and (2) a protein content of ≤1.0% calculated by multiplying a nitrogen content measured by a Kjeldahl method by a coefficient of 6.25. The (B) probiotics comprise one or more chosen from bifidobacteria, lactic acid bacteria, Bacillus subtilis, butyric acid-producing bacteria, lactic acid-utilizing bacteria and propionic acid-producing bacteria and has a water content of ≤20%. COPYRIGHT: (C)2010,JPO&INPIT
    • 要解决的问题:提供通过使用共生菌,益生菌和益生元的组合来调节肠道环境的方法。 解决方案:肠道环境调理方法包括(A)益生元和(B)益生菌的共生菌的口服给药,以诱导肠道内乳酸和糖的生成和肠环境的调理。 (A)益生元包括四孢杆菌的水解胚乳,其特征在于(1)通过在使用支链淀粉作为分子标记的高效液相色谱上通过凝胶过滤获得的重均分子量为3-50kDa的半乳甘露聚糖,和(2) 通过将通过凯氏定氮法测量的氮含量乘以6.25的系数计算的蛋白质含量≤1.0%。 (B)益生菌含有选自双歧杆菌,乳酸菌,枯草芽孢杆菌,丁酸生产菌,乳酸利用菌和丙酸生产菌中的一种或多种,​​水含量≤20%。 版权所有(C)2010,JPO&INPIT