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    • 10. 发明专利
    • Polymer of novel nitrogen-containing monoterpene derivative
    • 含氮单体衍生物的聚合物
    • JPS5781466A
    • 1982-05-21
    • JP14537681
    • 1981-09-14
    • Taito Kk
    • TOOYAMA RIYOUSUKEINOUE HIROYUKISHINGUU TETSUOTAKEDA YOSHIOIKUMOTO TAKESHIOKUYAMA HIDETOSHIYAMAMOTO OSAMU
    • C07D221/02C07D221/04C09B57/00
    • NEW MATERIAL:Dimer and trimer of a novel nitrogen-containing monoterpene derivatives of formula I W formula IV (R
      1 is methyl ethyl, CH
      2 COOCH
      3 , phenyl; R
      2 is COOCH
      3 ; R
      3 is H, methyl; R
      4 is H, methyl, hydroxymethyl).
      EXAMPLE: The compound of formula VI.
      USE: Synthetic intermediate of dyes, pigments of medicines, analysis of pharmaceutical activity of iridoid compounds, blue protein and other uses.
      PREPARATION: The saccharide part is removed from an iridoid by hydrolysis to obtain the very reactive aglycon and a compound containing a primary amino group is made to act on the aglycon to replace the oxygen atom readily with a nitrogen atom of a primary nitrogen group to produce a nitrogen-containing six- membered ring. For example, a compound of formula III is heated under an oxygen-free condition to give the compound of formula I.
      COPYRIGHT: (C)1982,JPO&Japio
    • 新物质:式I - 式IV的新型含氮单萜衍生物(R1是甲基乙基,CH2COOCH3,苯基; R2是COOCH3; R3是H,甲基; R4是H,甲基,羟甲基)的二聚体和三聚体。 实施例:式VI化合物。 用途:染料合成中间体,药物颜料,环烯醚萜类化合物的药物活性分析,蓝蛋白等用途。 制备:通过水解将糖类部分从环烯醚萜类中除去,得到非常反应性的糖苷配基,使含有伯氨基的化合物作用于糖苷配基上,以容易地与原氮基团的氮原子替代氧原子,从而产生 含氮六元环。 例如,将式III化合物在无氧条件下加热得到式I化合物。