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1. 发明授权

US5241080A Process for stabilizing dibenzylidenesorbitols and composition thereof 失效
标题翻译：稳定二苯基二苯醚的方法及其组合物
公开(公告)号：US5241080A
公开(公告)日：1993-08-31
申请号：US904488
申请日：1992-06-25
申请人： Tadashi Kobayashi , Hiroaki Matsuno , Shoji Obuchi
发明人： Tadashi Kobayashi , Hiroaki Matsuno , Shoji Obuchi
IPC分类号： C08K5/09 , C08K5/1575
CPC分类号： C08K5/09 , C08K5/1575
摘要： A process for stabilizing dibenzylidenesorbitols comprising incorporating 0.05-20 pts. wt. sorbic acid and/or potassium sorbate in 100 pts. wt. dibenzylidenesorbitol represented by the following formula, ##STR1## and a stabilized dibenzylidenesorbitol composition formed thereby. The storage stability of dibenzylidenesorbitols is thus greatly improved.

2. 发明授权

US4923951A Production process of aromatic polyamide 失效
标题翻译：芳香族聚酰胺的生产工艺
公开(公告)号：US4923951A
公开(公告)日：1990-05-08
申请号：US306943
申请日：1989-02-07
申请人： Tadashi Kobayashi , Shouji Obuchi , Hiroaki Matsuno , Mitsuo Wada , Hiroshi Takayanagi
发明人： Tadashi Kobayashi , Shouji Obuchi , Hiroaki Matsuno , Mitsuo Wada , Hiroshi Takayanagi
IPC分类号： C08G18/34 , C08G69/28 , C08G69/32
CPC分类号： C08G69/32 , C08G18/341 , C08G69/28
摘要： An aromatic polyamide is produced by subjecting an aromatic diisocyanate and an aromatic dicarboxylic acid to polycondensation in the presence of an alkali metal compound and/or an alkaline earth metal compound as a catalyst in an aprotonic polar solvent. The aromatic polyamide can be rendered suitable for use in the production of high-tenacity fibers by charging in advance the solvent, aromatic dicarboxylic acid and catalyst in a mixing system, reducing the water content in the mixing system to at least 50 ppm and then introducing the aromatic diisocyanate to conduct the polycondensation.

3. 发明授权

US06555645B1 Degradable polyurethane resin 失效
标题翻译：可降解聚氨酯树脂
公开(公告)号：US06555645B1
公开(公告)日：2003-04-29
申请号：US09831408
申请日：2001-05-09
申请人： Kan Ikeda , Hiroaki Matsuno , Naoki Sato
发明人： Kan Ikeda , Hiroaki Matsuno , Naoki Sato
IPC分类号： C08G1875
CPC分类号： C08G18/4269 , C08G18/42 , C08G18/4238 , C08G18/757 , C08G18/758 , C08G18/7831 , C08G18/798 , C08G2230/00
摘要： The invention is a degradable polyurethane resin obtained by reacting 2,5-/2,6-diisocyanatomethylbicyclo[2.2.1]heptane and/or a modified compound thereof with polyol comprising a single compound, mixture or copolycondensate selected from the group consisting of (A) polyhydroxycarboxylate polyol, (B) aliphatic polyester polyol and (C) saccharides, or (D) straight or branched polyol formed by condensation of (A) and/or (B) with aliphatic polyhydric alcohol having functionality of three or more, and the polyurethane resin has hydralyzability and biodegradability, is excellent in rigidity and elasticity in combination with flexibility as compared with conventionally known biodegradable resin, and can provide formed articles having outstandingly high elasticity and elongation and other unprecedented properties.
摘要翻译：本发明是通过使2,5- / 2,6-二异氰酸甲酯基双环[2.2.1]庚烷和/或其改性化合物与多元醇反应得到的可降解聚氨酯树脂，所述多元醇包含单一化合物，混合物或共缩聚物，其选自（ A）多羟基羧酸酯多元醇，（B）脂肪族聚酯多元醇和（C）糖类，或（D）通过（A）和/或（B）与官能度为3以上的脂肪族多元醇缩合形成的直链或支链多元醇，以及聚氨酯树脂具有可水解性和生物降解性，与常规已知的可生物降解树脂相比，刚性和弹性与柔韧性相比优异，并且可以提供具有突出的高弹性和伸长率等前所未有的性能的成型制品。

4. 发明申请

US20110039764A1 THERAPEUTIC COMPOSITION FOR BONE INFECTIOUS DISEASE 审中-公开
标题翻译：用于骨感染疾病的治疗组合物
公开(公告)号：US20110039764A1
公开(公告)日：2011-02-17
申请号：US12912104
申请日：2010-10-26
申请人： Hiroaki Matsuno , Masamichi Hashimoto , Yoshiaki Miyata , Teruzou Miyoshi
发明人： Hiroaki Matsuno , Masamichi Hashimoto , Yoshiaki Miyata , Teruzou Miyoshi
IPC分类号： A61K38/12 , A61K31/7036 , A61K31/65 , A61P31/04
CPC分类号： A61K31/7036 , A61K31/65
摘要： A biodegradable composition containing an antibiotic or a physiologically active substance for use in surgical treatment of infection. A highly safe and biocompatible composition showing appropriately sustained release of an antibiotic or physiologically active substance which produces excellent antibiotic and bone regenerating effects. A composition having excellent effects in treatment of bone infection occurring after operations for total arthroplasty and/or bone fracture. (1) A medical composition for treatment of bone infection comprising an antibiotic and a polysaccharide.
摘要翻译：一种可生物降解的组合物，其含有用于外科治疗感染的抗生素或生理活性物质。显示适当缓释抗生素或生理活性物质的高度安全和生物相容的组合物，其产生优异的抗生素和骨再生效果。一种在完全关节成形术和/或骨折手术后发生的骨感染治疗具有优异效果的组合物。（1）一种用于治疗骨感染的医药组合物，其包含抗生素和多糖。

5. 发明申请

US20060153893A1 Therapeutic composition for bone infectious disease 审中-公开
标题翻译：骨传染病治疗组合物
公开(公告)号：US20060153893A1
公开(公告)日：2006-07-13
申请号：US10509323
申请日：2003-04-08
申请人： Hiroaki Matsuno , Masamichi Hashimoto , Yoshiaki Miyata , Teruzuo Miyoshi
发明人： Hiroaki Matsuno , Masamichi Hashimoto , Yoshiaki Miyata , Teruzuo Miyoshi
IPC分类号： A61K38/14 , A61K31/728 , A61K31/7034 , A61F2/00
CPC分类号： A61K31/7036 , A61K31/65
摘要： A biodegradable composition containing an antibiotic or a physiologically active substance for use in surgical treatment of infection. A highly safe and biocompatible composition showing appropriately sustained release of an antibiotic or physiologically active substance which produces excellent antibiotic and bone regenerating effects. A composition having excellent effects in treatment of bone infection occurring after operations for total arthroplasty and/or bone fracture. (1) A medical composition for treatment of bone infection comprising an antibiotic and a polysaccharide.
摘要翻译：一种可生物降解的组合物，其含有用于外科治疗感染的抗生素或生理活性物质。显示适当缓释抗生素或生理活性物质的高度安全和生物相容的组合物，其产生优异的抗生素和骨再生效果。一种在完全关节成形术和/或骨折手术后发生的骨感染治疗具有优异效果的组合物。（1）一种用于治疗骨感染的医药组合物，其包含抗生素和多糖。

6. 发明授权

US5763687A Preparation process for aromatic mononitro compounds 失效
标题翻译：芳香族单硝基化合物的制备方法
公开(公告)号：US5763687A
公开(公告)日：1998-06-09
申请号：US763146
申请日：1996-12-10
申请人： Jyoji Morisaki , Masaaki Iijima , Kouki Oogaki , Hiroaki Matsuno , Takashi Yamaguchi , Katsuharu Miyata
发明人： Jyoji Morisaki , Masaaki Iijima , Kouki Oogaki , Hiroaki Matsuno , Takashi Yamaguchi , Katsuharu Miyata
IPC分类号： B01J19/24 , C07C201/08 , C07C205/06 , C07C205/12 , C07C205/00 , C07C201/00
CPC分类号： C07C201/08 , B01J19/2415 , B01J2219/00186
摘要： An improved preparation process for an aromatic mononitro compound comprising reacting an aromatic compound with mixed acid consisting of nitric acid, sulfuric acid or phosphoric acid and water, wherein these flow to react with each other in a reactor comprising a tube inside of which more than one twisted tabular members are aligned in sequence in a manner that a front margin of a twisted tabular member is substantially perpendicular to an back margin of the preceding member, can resolve a number of problems such as an inadequate mixing efficiency, reduction of a reaction rate, associated voluminal increase/complication of a reactor and difficulty in securing safety as well as provide the aromatic mononitro compound with minimal amount of by-products in a considerably short period.
摘要翻译：一种改进的芳族单硝基化合物的制备方法，包括使芳族化合物与硝酸，硫酸或磷酸和水组成的混合酸反应，其中这些流动在包含管内的多个反应器的反应器中彼此反应扭曲的平板状构件按照使得扭曲的平板状构件的前缘基本上垂直于前一构件的后缘的方式顺序排列，可以解决许多问题，例如不充分的混合效率，降低反应速率，相关的体积增加/反应器的并发症和难以确保安全性，以及在相当短的时间内提供芳香族单硝基化合物与最少量的副产物。

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