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1. 发明申请

WO2003092777A1 AEROSOL MEDICATION DELIVERY APPARATUS WITH NARROW ORIFICE 审中-公开
标题翻译：具有NARROW ORIFICE的AEROSOL MEDICATION DELIVERY APPARATUS
公开(公告)号：WO2003092777A1
公开(公告)日：2003-11-13
申请号：PCT/US2003/012121
申请日：2003-05-02
申请人： TRUDELL MEDICAL INTERNATIONAL , GRYCHOWSKI, Jerry, R. , FOLEY, Martin, P.
发明人： GRYCHOWSKI, Jerry, R. , FOLEY, Martin, P.
IPC分类号： A61M16/00
CPC分类号： A61M15/0086 , A61M15/0016 , A61M15/0018 , A61M15/009 , A61M16/208
摘要： An aerosol medication delivery apparatus includes a holding chamber (4) having an input end (6) and an output end (14) and defining an interior space (19). The output end comprises an orifice (47) having a cross-sectional area of less than about 60 mm 2 . In one preferred embodiment, the orifice has a circular cross-section. Preferably, the orifice has a diameter of between about 2.0 mm and about 7.50 mm. In one preferred embodiment, an inhalation valve and exhalation valve (110) is located at the output end. A method of using the holding chamber is also provided.
摘要翻译：气溶胶药物输送装置包括具有输入端（6）和输出端（14）并限定内部空间（19）的保持室（4）。输出端包括具有小于约60mm 2的横截面面积的孔口（47）。在一个优选实施例中，孔口具有圆形横截面。优选地，孔口具有在约2.0mm至约7.50mm之间的直径。在一个优选实施例中，吸入阀和呼气阀（110）位于输出端。还提供了使用保持室的方法。

2. 发明申请

WO2009105515A3 RESPIRATORY MUSCLE ENDURANCE TRAINING DEVICE AND METHOD FOR THE USE THEREOF 审中-公开
公开(公告)号：WO2009105515A3
公开(公告)日：2009-08-27
申请号：PCT/US2009/034474
申请日：2009-02-19
申请人： TRUDELL MEDICAL INTERNATIONAL , FOLEY, Martin, P. , GRYCHOWSKI, Jerry, R.
发明人： FOLEY, Martin, P. , GRYCHOWSKI, Jerry, R.
IPC分类号： A63B23/18
摘要： A respiratory muscle endurance training device (RMET) includes a chamber and a patient interface (53). In one implementation, one or both of a C02 sensor or a temperature sensor can be coupled to the chamber or patient interface to provide the user or caregiver with indicia about the C02 level in, or the temperature of, the chamber or patient interface, and/or the duration of use of the device. In another implementation, the RMET may have a fixed volume portion adjustable to contain a measured portion of a specific patient's inspiratory volume capacity. Methods of using the device are also provided.

3. 发明申请

WO2008134330A2 AEROSOL DELIVERY SYSTEM 审中-公开
标题翻译：气溶胶输送系统
公开(公告)号：WO2008134330A2
公开(公告)日：2008-11-06
申请号：PCT/US2008/061203
申请日：2008-04-23
申请人： TRUDELL MEDICAL INTERNATIONAL , FOLEY, Martin, P. , GRYCHOWSKI, Jerry, R. , MEYER, Adam , SCHMIDT, James
发明人： FOLEY, Martin, P. , GRYCHOWSKI, Jerry, R. , MEYER, Adam , SCHMIDT, James
IPC分类号： A61M15/00
CPC分类号： A61M16/14 , A61M15/0015 , A61M15/0018 , A61M15/0068 , A61M15/0086 , A61M15/009 , A61M16/0003 , A61M16/0009 , A61M16/0078 , A61M16/0084 , A61M16/04 , A61M16/08 , A61M16/0816 , A61M16/0833 , A61M16/0841 , A61M16/085 , A61M16/0858 , A61M16/208 , A61M2016/0027 , A61M2205/0233 , A61M2205/3331 , A61M2205/3368
摘要： Ventilator circuit aerosol delivery systems used to administer medication to a patient are disclosed. In one implementation, a metered dose inhaler ("MDI") ventilator assembly may include a housing that defines an interior space, an inhalation port that defines an inhalation passageway in communication with the interior space, an exhalation port that defines an exhalation passageway in communication with the interior space, a patient port that defines a patient passageway in communication with the interior space, and a MDI receptacle positioned on the housing and in communication with the interior space. The MDI receptacle is operative to receive a MDI container and dispense an aerosolized medication within the MID container into the interior space so that during inhalation, an inhalation flow including the aerosolized medication may flow through the inhalation port, the interior space, and the patient port. Conversely, during exhalation, gases, moisture, condensation, and/or mucus expelled from the patient flow through the patient port, the interior space, and the exhalation port.
摘要翻译：公开了用于向患者施用药物的呼吸机回路气雾剂输送系统。在一个实施例中，定量吸入器（“MDI”）通气机组件可以包括限定内部空间的外壳，限定与内部空间连通的吸入通道的吸入端口，限定内部空间中的呼气通道的呼气端口与内部空间连通，限定与内部空间连通的患者通道的患者端口，以及定位在外壳上并与内部空间连通的MDI容器。 MDI容器可操作以接收MDI容器并将MID容器内的雾化药物分配到内部空间中，使得在吸入期间，包括雾化药物的吸入流可以流过吸入端口，内部空间和患者端口。相反，在呼气期间，从患者排出的气体，湿气，凝结物和/或粘液流过患者端口，内部空间和呼气端口。

4. 发明申请

WO2008024375A2 RESPIRATORY MUSCLE ENDURANCE TRAINING DEVICE AND METHOD FOR THE USE THEREOF 审中-公开
标题翻译：呼吸肌训练装置及其使用方法
公开(公告)号：WO2008024375A2
公开(公告)日：2008-02-28
申请号：PCT/US2007/018527
申请日：2007-08-21
申请人： TRUDELL MEDICAL INTERNATIONAL , FOLEY, Martin , GRYCHOWSKI, Jerry, R.
发明人： FOLEY, Martin , GRYCHOWSKI, Jerry, R.
IPC分类号： A63B23/18
CPC分类号： A63B23/18 , A61B5/01 , A61B5/0836 , A61B5/097 , A61B5/486 , A63B2230/433
摘要： A respiratory muscle endurance training device (RMET) includes a chamber and a patient interface. In one implementation, one or both of a CO 2 sensor or a temperature sensor can be coupled to the chamber or patient interface to provide the user or caregiver with indicia about the CO 2 level in, or the temperature of, the chamber or patient interface, and/or the duration of use of the device. In another implementation, the RMET may have a fixed volume portion adjustable to contain a measured portion of a specific patient's inspiratory volume capacity. Methods of using the device are also provided.
摘要翻译：呼吸肌耐力训练装置（RMET）包括腔室和患者接口。在一个实施方式中，CO 2传感器或温度传感器中的一个或两个可以耦合到腔室或患者接口，以向使用者或护理人员提供关于CO 2 2 / >腔室或患者接口的水平或温度，和/或装置的使用持续时间。在另一实施方式中，RMET可以具有可调整的固定的体积部分以包含特定患者的吸气量容量的测量部分。还提供了使用该设备的方法。

5. 发明申请

WO2004071549A2 VENTILATOR CIRCUIT AND THE METHOD FOR THE USE THEREOF 审中-公开
标题翻译：通风机电路及其使用方法
公开(公告)号：WO2004071549A2
公开(公告)日：2004-08-26
申请号：PCT/IB2004/000333
申请日：2004-02-10
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： GRYCHOWSKI, Jerry, R. , FOLEY, Martin, P. , DUNN, Michael, S.
IPC分类号： A61M
CPC分类号： A61M16/208 , A61M15/0015 , A61M15/0018 , A61M15/0086 , A61M15/009 , A61M16/01 , A61M16/08 , A61M16/0833
摘要： A ventilator circuit (2) for use in administering medication to a patient includes a chamber housing (4) defining an interior space (6) and having an input end (8) and an output end (10) and a one-way inhalation valve (56) positioned upstream of the interior space (6). The one-way inhalation valve (56) is operative to permit a flow of medication into the interior space (6) of the chamber housing (4). An inhalation conduit (88) communicates with the output end (10) of the chamber (4) and is adapted to transmit the medication to the patient. An exhaust conduit (18) is connected to the inhalation conduit (68) and a one-way exhaust valve (78) is located in the exhaust conduit (18). The one way exhaust valve (78) is adapted to prevent a backflow of gas from the exhaust conduit (18) into the inhalation conduit (58). A method of administering a medication to a patient includes transmitting oxygen from a gas source through a holding chamber (4) and an inhalation conduit (88) to the patient during an inhalation sequence and introducing the medication into the holding chamber (4). The method further includes preventing a substantial transmission of an exhaust gas into the holding chamber (4) during an exhalation sequence and transmitting a substantial portion of the exhaust gas into the exhaust conduit (18) during exhalation. The method also includes preventing a substantial transmission of the exhaust gas from the exhaust conduit (18) into the inhalation conduit during subsequent inhalation sequences.
摘要翻译：用于向患者施用药物的呼吸机回路（2）包括限定内部空间（6）并具有输入端（8）和输出端（10）的腔室壳体（4）和单向吸入阀（56）定位在所述内部空间（6）的上游。单向吸入阀（56）可操作以允许药物流入腔室（4）的内部空间（6）。吸入管道（88）与腔室（4）的输出端（10）连通并适于将药物传送给患者。排气管道（18）连接到吸入管道（68），并且单向排气阀（78）位于排气管道（18）中。单向排气阀（78）适于防止气体从排气管道（18）回流到吸入管道（58）中。向患者施用药物的方法包括在吸入顺序期间将氧从气体源通过保持室（4）和吸入管道（88）传输到患者，并将药物引入到保持室（4）中。该方法还包括防止在呼气顺序期间废气进入保持室（4）的实质性传输，并且在呼气期间将废气的大部分传送到排气管道（18）中。该方法还包括防止废气在随后的吸入序列期间从排气管道（18）进入吸入管道的实质性传输。

6. 发明公开

EP1311314A2 NASAL INHALER 审中-公开
标题翻译： NASALER气雾
公开(公告)号：EP1311314A2
公开(公告)日：2003-05-21
申请号：EP01921705.8
申请日：2001-04-12
申请人： Trudell Medical International
发明人： FOLEY, Martin , GRYCHOWSKI, Jerry, R. , MACRAE, John, R.
IPC分类号： A61M15/08 , A61M15/00
摘要： A nasal inhaler for introducing a substance to a nasal cavity of a user. The nasal inhaler comprises a chamber having an interior and an exterior, an outlet comprising an air exit passageway in flow communication with the interior of the chamber, a one-way air inlet valve in one-way flow communication with the interior of the chamber, and a dosage inlet passageway in flow communication with the interior of the chamber. A container includes a dispensing portion disposed in the dosage inlet passageway. In preferred embodiment, an adapter defines the dosage inlet passageway and is connected to the chamber. A mask also can be connected to the outlet. A method for dispensing a substance into the nasal cavity of the user comprises inserting the outlet into the nasal cavity, dispensing the substance into the chamber and inhaling through the outlet. A method for assembling a nasal inhaler assembly also is provided.

7. 发明授权

EP2059309B1 RESPIRATORY MUSCLE ENDURANCE TRAINING DEVICE AND METHOD FOR THE USE THEREOF 有权转让
标题翻译：训练设备，以加强使用呼吸肌及其方法
公开(公告)号：EP2059309B1
公开(公告)日：2013-07-03
申请号：EP07837182.0
申请日：2007-08-21
申请人： Trudell Medical International
发明人： FOLEY, Martin , GRYCHOWSKI, Jerry, R.
IPC分类号： A63B23/18
CPC分类号： A63B23/18 , A61B5/01 , A61B5/0836 , A61B5/097 , A61B5/486 , A63B2230/433

8. 发明公开

EP2259849A2 RESPIRATORY MUSCLE ENDURANCE TRAINING DEVICE AND METHOD FOR THE USE THEREOF 审中-公开
标题翻译：呼吸肌耐力训练装置和方法中使用
公开(公告)号：EP2259849A2
公开(公告)日：2010-12-15
申请号：EP09712996.9
申请日：2009-02-19
申请人： Trudell Medical International
发明人： FOLEY, Martin, P. , GRYCHOWSKI, Jerry, R.
IPC分类号： A63B23/18
CPC分类号： A63B23/18 , A63B21/00069 , A63B21/0085 , A63B71/0619 , A63B2071/0625 , A63B2230/433 , A63B2230/50
摘要： A respiratory muscle endurance training device (RMET) includes a chamber and a patient interface (53). In one implementation, one or both of a C02 sensor or a temperature sensor can be coupled to the chamber or patient interface to provide the user or caregiver with indicia about the C02 level in, or the temperature of, the chamber or patient interface, and/or the duration of use of the device. In another implementation, the RMET may have a fixed volume portion adjustable to contain a measured portion of a specific patient's inspiratory volume capacity. Methods of using the device are also provided.

9. 发明授权

EP2155305B1 AEROSOL DELIVERY SYSTEM 有权转让
公开(公告)号：EP2155305B1
公开(公告)日：2018-06-06
申请号：EP08746593.6
申请日：2008-04-23
申请人： Trudell Medical International
发明人： FOLEY, Martin, P. , GRYCHOWSKI, Jerry, R. , MEYER, Adam , SCHMIDT, James
IPC分类号： A61M16/00 , A61M16/08 , A61M16/14 , A61M16/20 , A61M15/00 , A61M16/04
CPC分类号： A61M16/14 , A61M15/0015 , A61M15/0018 , A61M15/0068 , A61M15/0086 , A61M15/009 , A61M16/0003 , A61M16/0009 , A61M16/0078 , A61M16/0084 , A61M16/04 , A61M16/08 , A61M16/0816 , A61M16/0833 , A61M16/0841 , A61M16/085 , A61M16/0858 , A61M16/208 , A61M2016/0027 , A61M2205/0233 , A61M2205/3331 , A61M2205/3368
摘要： Ventilator circuit aerosol delivery systems used to administer medication to a patient are disclosed. In one implementation, a metered dose inhaler (“MDI”) ventilator assembly may include a housing that defines an interior space, an inhalation port that defines an inhalation passageway in communication with the interior space, an exhalation port that defines an exhalation passageway in communication with the interior space, a patient port that defines a patient passageway in communication with the interior space, and a MDI receptacle positioned on the housing and in communication with the interior space. The MDI receptacle is operative to receive a MDI container and dispense an aerosolized medication within the MID container into the interior space so that during inhalation, an inhalation flow including the aerosolized medication may flow through the inhalation port, the interior space, and the patient port. Conversely, during exhalation, gases, moisture, condensation, and/or mucus expelled from the patient flow through the patient port, the interior space, and the exhalation port.

10. 发明公开

EP2155305A2 AEROSOL DELIVERY SYSTEM 有权转让
标题翻译： AEROSOLABGABESYSTEM
公开(公告)号：EP2155305A2
公开(公告)日：2010-02-24
申请号：EP08746593.6
申请日：2008-04-23
申请人： Trudell Medical International
发明人： FOLEY, Martin, P. , GRYCHOWSKI, Jerry, R. , MEYER, Adam , SCHMIDT, James
IPC分类号： A61M15/00
CPC分类号： A61M16/14 , A61M15/0015 , A61M15/0018 , A61M15/0068 , A61M15/0086 , A61M15/009 , A61M16/0003 , A61M16/0009 , A61M16/0078 , A61M16/0084 , A61M16/04 , A61M16/08 , A61M16/0816 , A61M16/0833 , A61M16/0841 , A61M16/085 , A61M16/0858 , A61M16/208 , A61M2016/0027 , A61M2205/0233 , A61M2205/3331 , A61M2205/3368
摘要： Ventilator circuit aerosol delivery systems used to administer medication to a patient are disclosed. In one implementation, a metered dose inhaler (“MDI”) ventilator assembly may include a housing that defines an interior space, an inhalation port that defines an inhalation passageway in communication with the interior space, an exhalation port that defines an exhalation passageway in communication with the interior space, a patient port that defines a patient passageway in communication with the interior space, and a MDI receptacle positioned on the housing and in communication with the interior space. The MDI receptacle is operative to receive a MDI container and dispense an aerosolized medication within the MID container into the interior space so that during inhalation, an inhalation flow including the aerosolized medication may flow through the inhalation port, the interior space, and the patient port. Conversely, during exhalation, gases, moisture, condensation, and/or mucus expelled from the patient flow through the patient port, the interior space, and the exhalation port.
摘要翻译：公开了用于向患者施用药物的呼吸机回路气雾剂输送系统。在一个实施方案中，定量吸入器（“MDI”）呼吸器组件可以包括限定内部空间的壳体，限定与内部空间连通的吸入通道的吸入口，限定呼吸通道的呼气口所述内部空间设置有限定与所述内部空间连通的患者通道的患者口，以及位于所述外壳上并与所述内部空间连通的MDI容器。 MDI容器操作以接收MDI容器并将MID容器内的雾化药物分配到内部空间中，使得在吸入期间，包括雾化药物的吸入流可以流过吸入口，内部空间和患者口。相反，在呼气期间，从患者排出的气体，水分，冷凝物和/或粘液流过患者口，内部空间和呼气口。

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