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1. 发明专利

AU2275701A Hypodermic needle with weeping tip and method of use 未知
公开(公告)号：AU2275701A
公开(公告)日：2001-07-03
申请号：AU2275701
申请日：2000-12-18
申请人： TRICARDIA LLC , TASSEL ROBERT A VAN , HOLMES DAVID R , SCHWARTZ ROBERT S
发明人： TASSEL ROBERT A VAN , HOLMES DAVID R , SCHWARTZ ROBERT S
IPC分类号： C12N15/09 , A61K31/711 , A61K48/00 , A61M5/158 , A61M5/32 , A61M25/00 , A61M31/00 , A61P43/00
摘要： The invention provides surgical needles with a porous distal portion from which a liquid injectate will weep or ooze multidirectionally under injection pressure while the porous distal portion of the needle is inserted into a body surface. The porous distal portion of the needle can be fabricated from a porous carbon, metal, ceramic or polymer and preferably has a decreasing gradient of impedance to fluid flowing to the point of the needle to compensate for the falling off of injection pressure as fluid moves towards the point, thereby ensuring uniform weeping of the injectate along the injection course. The needle is adapted for attachment to a catheter or syringe. In another embodiment, a surgical assemblage is provided wherein a porous distal portion having similar fluid flow characteristics is located along the distal end of a catheter, and a needle point is attached to the distal end of the catheter (e.g., a steerable catheter) for piercing tissue. A guidance catheter can be used to direct the invention devices to a remote internal injection site. The invention devices and methods can be used to inject fluids (including those containing nucleic acids for gene therapy) into interior body walls or tissue, such as a beating heart, without substantial loss of fluid and without substantial damage to tissue caused by injectate.

2. 发明申请

WO02083228A2 SYRINGE SYSTEM 审中-公开
标题翻译： SYRINGE系统
公开(公告)号：WO02083228A2
公开(公告)日：2002-10-24
申请号：PCT/US0211681
申请日：2002-04-11
申请人： TRICARDIA LLC , SCHWARTZ ROBERT S , VANTASSEL ROBERT A , HOLMES DAVID R
发明人： SCHWARTZ ROBERT S , VANTASSEL ROBERT A , HOLMES DAVID R
IPC分类号： A61B17/00 , A61B17/34 , A61M5/145 , A61M5/158 , A61M5/168 , A61M5/31 , A61M5/32 , A61M25/00
CPC分类号： A61M5/158 , A61B17/3478 , A61B2017/00247 , A61B2018/00392 , A61M5/14546 , A61M5/16813 , A61M5/3291 , A61M2005/14513 , A61M2005/3123 , A61M2025/0008 , A61M2025/0057 , A61M2025/0079 , A61M2025/0081 , A61M2025/0091
摘要： A medical device is provided having a needle or a catheter, insertable into a living body, which defines a plurality of holes in fluid communication with a central lumen. The holes may be of various patterns located and angled to create a desired injectate cloud pattern when an injectate is forced through the central lumen and through the plurality of holes. One embodiment provides various designs including a moveable sheath or stylet used to selectively occlude one or more of the holes while in use, thereby providing an operating physician a way to manipulate the cloud pattern anytime during the introduction of the injectate. A reducer may be used in conjunction with these needles which provides an increased degree of control when injecting very small quantities of fluid.
摘要翻译：提供具有可插入生物体中的针或导管的医疗装置，其限定与中心腔流体连通的多个孔。当注射剂被迫穿过中心腔并穿过多个孔时，孔可以是各种图案，其定位和成角度以产生期望的注射云图案。一个实施例提供了各种设计，包括用于在使用中选择性地闭塞一个或多个孔的可移动护套或探针，从而为操作医师提供在注射器引入期间随时操作云图案的方式。减速器可以与这些针结合使用，当注射非常少量的流体时，可以提供更高程度的控制。

3. 发明专利

JP2000350705A PRESSURE/TEMPERATURE/FLOW MONITORING APPARATUS FOR VASCULAR IMPLANTATION 失效
公开(公告)号：JP2000350705A
公开(公告)日：2000-12-19
申请号：JP2000133068
申请日：2000-05-02
申请人： TRICARDIA LLC
发明人： VANTASSEL ROBERT A , SCHWARTZ ROBERT S , HOLMES DAVID R
IPC分类号： A61B5/00 , A61B5/01 , A61B5/0205 , A61B5/0215 , A61B5/026 , A61B5/028 , A61B5/0295 , A61B17/00 , A61F2/82
摘要： PROBLEM TO BE SOLVED: To enable a medical specialist to easily diagnose and remedy various medical conditions by including a means fixed on a support means for detecting one measurable parameter and a means on the supporting means for percutaneously transmitting a signal representing a detection parameter to a receiver by a telemetry link. SOLUTION: A monitoring apparatus for medical care includes a support member 10 shown as a self or balloon dilation stent, on which an electronic module 12 which is fitted to supply electric power with an embedded electric source 14 connected with a conductor 16 is fixed. The electric source 14 is contained inside a fluid impervious casing 18 in the body, and the electronic circuit containing the module 12 has a closed electric field-through 22. When it is disposed in a cavity of a blood vessel, the support unit 10 is tubular and let blood stream pass through. It is possible to obtain excellent estimation of the left ventricle end expanding period pressure significant to remedy CHF and high blood pressure by disposing a stent in a pulmonary artery or its arterial branch with a temperature/pressure/flow volume measuring circuit.

4. 发明申请

WO2011149913A3 MEDICAL DEVICES INCLUDING DUPLEX STAINLESS STEEL 审中-公开
标题翻译：包括双相不锈钢的医疗设备
公开(公告)号：WO2011149913A3
公开(公告)日：2012-04-05
申请号：PCT/US2011037707
申请日：2011-05-24
申请人： MAYO FOUNDATION , SANDHU GURPREET S , SIMARI ROBERT D , HOLMES DAVID R , DRAGOMIR DAESCU M DAN , PARAKKA ANTHONY P
发明人： SANDHU GURPREET S , SIMARI ROBERT D , HOLMES DAVID R , DRAGOMIR DAESCU M DAN , PARAKKA ANTHONY P
IPC分类号： A61F2/02 , A61F2/915 , A61L27/04 , A61L27/40
CPC分类号： A61F2/82 , A61F2/915 , A61F2230/0054 , A61L31/022 , A61L31/14
摘要： Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The endoprostheses comprise a tubular member capable of maintaining patency of a bodily vessel. The tubular member includes a duplex stainless steel (e.g., 2205 stainless steel), which may be magnetized.
摘要翻译：公开了医疗装置，例如内用假体，以及制造装置的方法。内用假体包括能够保持身体血管通畅的管状构件。管状构件包括可被磁化的双相不锈钢（例如2205不锈钢）。

5. 发明申请

WO0006239A2 CATHETER HAVING FLOW DIFFUSING TIP 审中-公开
标题翻译：具有流动扩口的导管
公开(公告)号：WO0006239A2
公开(公告)日：2000-02-10
申请号：PCT/US9917012
申请日：1999-07-27
申请人： TRICARDIA LLC
发明人： BERRY DAVID , HOLMES DAVID R , SCHWARTZ ROBERT S , VANTASSEL ROBERT A
IPC分类号： A61M25/00 , A61M25/14
CPC分类号： A61M25/0075 , A61M2025/0076
摘要： An intravascular catheter having a flow diffusing distal tip includes a plurality of cuts formed through the tubular wall thereof so as to define a plurality of generally U-shaped flaps, the flaps being disposed in at least one and preferably two axially displaced bands. When contrast fluid or the like is injected under pressure into the proximal end of the catheter, the flow of the liquid exits the openings in which the plurality of flaps are hinged, causing the flaps to vibrate and effectively eliminate any tendency for the contrast media to be expelled as a jet from the open distal end of the catheter. Having an open distal end allows the catheter to be passed over a guidewire.
摘要翻译：具有流动扩散远侧末端的血管内导管包括通过其管状壁形成的多个切口，以便限定多个大致U形的翼片，翼片设置在至少一个且优选两个轴向移位的带中。当在压力下将对比液或类似物注入导管的近端时，液体的流动离开多个襟翼铰接的开口，导致襟翼振动并有效地消除造影剂的任何倾向作为射流从导管的开放远端排出。具有开放的远端允许导管穿过导丝。

6. 发明专利

CA2444505A1 SYRINGE SYSTEM 未知
公开(公告)号：CA2444505A1
公开(公告)日：2002-10-24
申请号：CA2444505
申请日：2002-04-11
申请人： TRICARDIA LLC
发明人： VANTASSEL ROBERT A , SCHWARTZ ROBERT S , HOLMES DAVID R
IPC分类号： A61B17/00 , A61B17/34 , A61M5/145 , A61M5/158 , A61M5/168 , A61M5/31 , A61M5/32 , A61M25/00 , A61M5/20 , A61M5/315
摘要： A medical device is provided having a needle or a catheter, insertable into a living body, which defines a plurality of holes in fluid communication with a central lumen. The holes may be of various patterns located and angled to create a desired injectate cloud pattern when an injectate is forced through the central lumen and through the plurality of holes. One embodiment provide s various designs including a moveable sheath or stylet used to selectively occlude one or more of the holes while in use, thereby providing an operatin g physician a way to manipulate the cloud pattern anytime during the introduction of the injectate. A reducer may be used in conjunction with the se needles which provides an increased degree of control when injecting very small quantities of fluid.

7. 发明专利

NO20002244A 未知
公开(公告)号：NO20002244A
公开(公告)日：2000-11-06
申请号：NO20002244
申请日：2000-04-28
申请人： TRICARDIA LLC
发明人： VANTASSEL ROBERT A , SCHWARTZ ROBERT S , HOLMES DAVID R
IPC分类号： A61B5/00 , A61B5/01 , A61B5/0205 , A61B5/0215 , A61B5/026 , A61B5/028 , A61B5/0295 , A61B17/00 , A61F2/82
CPC分类号： A61F2/82 , A61B5/0031 , A61B5/02055 , A61B5/0215 , A61B5/026 , A61B5/413 , A61B5/6882 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623

8. 发明专利

NO980902L 未知
公开(公告)号：NO980902L
公开(公告)日：1999-09-03
申请号：NO980902
申请日：1998-03-02
申请人： TRICARDIA LLC
发明人： TASSEL ROBERT A VAN , SCHWARTZ ROBERT S , HOLMES DAVID R
IPC分类号： A61B17/00 , A61B17/34 , A61M25/08 , A61M5/32 , A61M5/34 , A61M25/00
摘要： An instrument for achieving rapid hemostasis at the conclusion of a catheterization procedure comprises a device for injecting a fluid hemostatic agent into a puncture wound that is operatively associated with a conventional introducer sheath component of the introducer used to gain assess to a blood vessel using the Seldinger technique. The hemostatic agent injection device includes a tubular member that can be concentrically disposed with a tubular introducer sheath so as to be slidable therealong and where the injection device includes a hemostatic agent inlet port at a proximal end thereof and an ejection port at a distal end, the two ports being interconnected by a lumen. In a first embodiment, the hemostatic agent injection device is adapted to coaxially surround the introducer sheath and in an alternate embodiment, the injection device is coaxially disposed within the lumen of the introducer sheath.

9. 发明专利

DE60033688T2 未知
公开(公告)号：DE60033688T2
公开(公告)日：2007-11-15
申请号：DE60033688
申请日：2000-12-18
申请人： TRICARDIA LLC
发明人： VANTASSEL ROBERT A , HOLMES DAVID R , SCHWARTZ ROBERT S
IPC分类号： A61B17/00 , C12N15/09 , A61K31/711 , A61K48/00 , A61M5/158 , A61M5/32 , A61M25/00 , A61M31/00 , A61P43/00
摘要： The invention provides surgical needles with a porous distal portion from which a liquid injectate will weep or ooze multidirectionally under injection pressure while the porous distal portion of the needle is inserted into a body surface. The porous distal portion of the needle can be fabricated from a porous carbon, metal, ceramic or polymer and preferably has a decreasing gradient of impedance to fluid flowing to the point of the needle to compensate for the falling off of injection pressure as fluid moves towards the point, thereby ensuring uniform weeping of the injectate along the injection course. The needle is adapted for attachment to a catheter or syringe. In another embodiment, a surgical assemblage is provided wherein a porous distal portion having similar fluid flow characteristics is located along the distal end of a catheter, and a needle point is attached to the distal end of the catheter (e.g., a steerable catheter) for piercing tissue. A guidance catheter can be used to direct the invention devices to a remote internal injection site. The invention devices and methods can be used to inject fluids (including those containing nucleic acids for gene therapy) into interior body walls or tissue, such as a beating heart, without substantial loss of fluid and without substantial damage to tissue caused by injectate.

10. 发明专利

DE60033688D1 未知
公开(公告)号：DE60033688D1
公开(公告)日：2007-04-12
申请号：DE60033688
申请日：2000-12-18
申请人： TRICARDIA LLC
发明人： VANTASSEL ROBERT A , HOLMES DAVID R , SCHWARTZ ROBERT S
IPC分类号： A61B17/00 , C12N15/09 , A61K31/711 , A61K48/00 , A61M5/158 , A61M5/32 , A61M25/00 , A61M31/00 , A61P43/00
摘要： The invention provides surgical needles with a porous distal portion from which a liquid injectate will weep or ooze multidirectionally under injection pressure while the porous distal portion of the needle is inserted into a body surface. The porous distal portion of the needle can be fabricated from a porous carbon, metal, ceramic or polymer and preferably has a decreasing gradient of impedance to fluid flowing to the point of the needle to compensate for the falling off of injection pressure as fluid moves towards the point, thereby ensuring uniform weeping of the injectate along the injection course. The needle is adapted for attachment to a catheter or syringe. In another embodiment, a surgical assemblage is provided wherein a porous distal portion having similar fluid flow characteristics is located along the distal end of a catheter, and a needle point is attached to the distal end of the catheter (e.g., a steerable catheter) for piercing tissue. A guidance catheter can be used to direct the invention devices to a remote internal injection site. The invention devices and methods can be used to inject fluids (including those containing nucleic acids for gene therapy) into interior body walls or tissue, such as a beating heart, without substantial loss of fluid and without substantial damage to tissue caused by injectate.

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