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1. 发明申请

WO2007019527A3 OPTICAL SENSOR AND METHODS FOR MEASURING MOLECULAR BINDING INTERACTIONS 审中-公开
公开(公告)号：WO2007019527A3
公开(公告)日：2007-02-15
申请号：PCT/US2006/030935
申请日：2006-08-04
申请人： TREX ENTERPRISES CORP. , RAUH-ADELMANN, Christine , TIGLI, Hus , MARTIN, Peter
发明人： RAUH-ADELMANN, Christine , TIGLI, Hus , MARTIN, Peter
IPC分类号： G01N33/48 , G06G7/48
摘要： Methods and devices for the measurement of molecular binding interactions. Preferred embodiments provide real-time measurements of kinetic binding and disassociation of molecules including binding and disassociation of protein molecules with other protein molecules and with other molecules. In preferred embodiments ligands are immobilized within pores of a porous silicon interaction region produced in a silicon substrate, after which analytes suspended in a fluid are flowed over the porous silicon region. Binding reactions occur when analyte molecules diffuse closely enough to the ligands to become bound. Preferably the binding and subsequent disassociation reactions are observed utilizing a white light source and thin film interference techniques with spectrometers arranged to detect changes in indices of refraction in the region where the binding and disassociation reactions occur. In preferred embodiments both ligands and analytes are delivered by computer controlled robotic fluid flow control techniques to the porous silicon interaction regions through microfluidic flow channels.

2. 发明申请

WO2010036220A1 MANY MILLION PIXEL IMAGE SENSOR 审中-公开
标题翻译：万亿像素图像传感器
公开(公告)号：WO2010036220A1
公开(公告)日：2010-04-01
申请号：PCT/US2008/011151
申请日：2008-09-26
申请人： TREX ENTERPRISES CORP. , MARTIN, Peter , JOHNSON, Paul , SEXTON, Chris
发明人： MARTIN, Peter , JOHNSON, Paul , SEXTON, Chris
IPC分类号： H01L31/062
CPC分类号： H01L27/14603 , H01L27/14634 , H01L27/14665
摘要： A CMOS image sensor with a many million pixel count. Applicants have developed techniques for combining its continuous layer photodiode CMOS sensor technology with CMOS integrated circuit lithography stitching techniques to provide digital cameras with an almost unlimited number of pixels. A preferred CMOS stitching technique exploits the precise alignment accuracy of CMOS stepper processes by using specialized mask sets to repeatedly produce a single pixel array pattern many times on a single silicon wafer with no pixel array discontinuities. The single array patterns are stitched together lithographically to form a pixel array of many million pixels. A continuous multilayer photodiode layer is deposited over the top of the many million pixel array to provide a many million pixel sensor with a fill factor of 100 percent or substantially 100 percent.
摘要翻译：具有数百万像素数的CMOS图像传感器。申请人已经开发出将连续层光电二极管CMOS传感器技术与CMOS集成电路光刻拼接技术相结合的技术，为数码相机提供几乎无限数量的像素。优选的CMOS拼接技术利用CMOS步进工艺的精确对准精度通过使用专门的掩模组在单个硅晶片上重复产生单个像素阵列图案多次而不存在像素阵列不连续性。将单阵列图案光刻地缝合在一起以形成数百万像素的像素阵列。连续的多层光电二极管层沉积在数百万像素阵列的顶部，以提供百万像素传感器，其填充因子为100％或基本为100％。

3. 发明申请

WO2006099216A1 DIGITAL X-RAY TOMOSYNTHESIS SYSTEM 审中-公开
标题翻译：数字X射线蛋白酶体系统
公开(公告)号：WO2006099216A1
公开(公告)日：2006-09-21
申请号：PCT/US2006/008745
申请日：2006-03-09
申请人： TREX ENTERPRISES CORP. , MARTIN, Peter , SPIVEY, Brett
发明人： MARTIN, Peter , SPIVEY, Brett
IPC分类号： G21K1/12 , H05G1/60 , A61B6/00 , G01N23/00
CPC分类号： A61B6/4441 , A61B6/025 , A61B6/4405 , A61B6/466 , A61B6/587 , A61B6/588 , G01N23/044 , G01N2223/419
摘要： Method and device for digital x-ray tomosynthesis. Tomographic and/or three-dimensional images of an object are obtained with an x-ray source and a digital x-ray image sensor. The source, object and sensor are positioned relative to each other and attenuatiation data is obtained for a large number of rays of x-radiation through the object. A special algorithm is provided to convert the data into images. To calculate the images the algorithm uses iterative processes with a least squares type technique but with generalized (as opposed to specific) functions. The algorithm solves for the functions which are the images. Preferred embodiments include a system having an x-ray point source with a cone of diverging x-rays, a two-dimensional digital x-ray image sensor, two linear translation stages to independently move both the x-ray source and the digital x-ray image sensor, two rotation mechanisms to rotate the two linear translation stages, a microprocessor to control the data acquisition, and a computer programmed with a special algorithm to calculate the tomographic images. A plurality of sets of digital data (representing x-ray algorithm images of an object) are acquired by the digital x-ray image sensor, with the x-ray source and the digital x-ray image sensor located at different positions and angles relative to the object. The digital data representing the x-ray attenuation images is stored in the computer.
摘要翻译：数字X射线断层合成的方法和装置。使用x射线源和数字X射线图像传感器获得物体的层析和/或三维图像。源，物体和传感器相对于彼此定位，并且通过物体获得大量X射线的光衰减数据。提供了一种特殊的算法来将数据转换为图像。为了计算图像，该算法使用具有最小二乘法技术的迭代过程，但是具有广义（与特定）功能相反。该算法解决了作为图像的功能。优选实施例包括具有具有发散x射线的锥体的x射线点源的系统，二维数字X射线图像传感器，用于独立地移动x射线源和数字x射线源的两个线性平移级，射线图像传感器，旋转两个线性转换阶段的两个旋转机构，一个微处理器来控制数据采集，以及一台用特殊算法编程的计算机来计算断层图像。多个数字数据组（表示对象的x射线算法图像）由数字X射线图像传感器获取，x射线源和数字X射线图像传感器位于不同的位置和角度相对对象。表示X射线衰减图像的数字数据被存储在计算机中。

4. 发明申请

WO2009150452A1 A PROCESS AND SYSTEM FOR DETERMINING THE POSITION AND VELOCITY OF AN OBJECT 审中-公开
标题翻译：用于确定对象的位置和速度的过程和系统
公开(公告)号：WO2009150452A1
公开(公告)日：2009-12-17
申请号：PCT/GB2009/050641
申请日：2009-06-09
申请人： BAE SYSTEMS PLC , MARTIN, Peter , MACLEAN, Adam, Bryce
发明人： MARTIN, Peter , MACLEAN, Adam, Bryce
IPC分类号： G01S13/22
CPC分类号： G01S13/227 , G01S13/582
摘要： A process for determining the position and velocity of an object is disclosed. The process comprises: -generating a first burst of pulses at a first pulse repetition frequency and subsequently receiving a first set of signals characteristic of the range and velocity of the object; -generating a second burst of pulses at a second pulse repetition frequency and subsequently receiving a second set of signals characteristic of range and velocity of the object; -generating a first data set representative of range and corresponding velocity values from the first set of signals; -generating a second data set representative of range and corresponding velocity values from the second set of signals; -summing a magnitude of a signal strength from each of the first and second data sets at corresponding range and velocity values; and, -comparing the magnitude of the summed signal strengths to a threshold value.
摘要翻译：公开了一种用于确定物体的位置和速度的过程。该过程包括： - 以第一脉冲重复频率产生第一脉冲串，随后接收特征为对象的范围和速度的第一组信号; - 以第二脉冲重复频率产生第二脉冲串，随后接收特征为所述对象的范围和速度的第二组信号; - 从第一组信号产生表示范围和相应速度值的第一数据集; - 产生代表来自所述第二组信号的范围和对应速度值的第二数据集; 在相应的范围和速度值下，从第一和第二数据组中的每个数据组中的信号强度的大小; 并且将相加的信号强度的幅度与阈值进行比较。

5. 发明申请

WO2008104764A1 ENGINE FUEL SUPPLY SYSTEM 审中-公开
标题翻译：发动机燃油供应系统
公开(公告)号：WO2008104764A1
公开(公告)日：2008-09-04
申请号：PCT/GB2008/000652
申请日：2008-02-27
申请人： INSPECS LIMITED , FLITCH LIMITED , MARTIN, Peter , SMITH, Andrew
发明人： MARTIN, Peter , SMITH, Andrew
IPC分类号： F02D41/00
CPC分类号： F02D41/0025 , F02D19/061 , F02D19/0615 , F02D19/0618 , F02D19/0623 , F02D19/0628 , F02D19/0647 , F02D19/066 , F02D19/0694 , F02D19/081 , F02D41/266 , F02D41/3094 , F02D2041/389 , F02D2400/11 , Y02T10/36
摘要： Apparatus for controlling dual fuel supply to a fuel injected engine having an electronic engine management system (1) that supplies a primary injector control signal (8) to each of primary fuel injectors (2), the apparatus comprising an emulator (11) that emulates the electrical characteristics of a primary injector, a fuel control switch (10) that switches the primary injector control signal (8) from the primary injector (2) to the emulator (11) when an alternative mode is selected, a monitor (16) that monitors the primary injector control signal (8) to produce a monitor signal, and a controller (4) that processes the monitor signal to derive an alternative control signal which is used to control the primary fuel supply or a mixture of the primary fuel and a secondary fuel such as LPG, to the engine. Preferably the primary fuel supply is modulated by controlling injector control pulses. A secondary fuel may also be injected (3) and controlled by the controller (4).
摘要翻译：一种用于控制向燃料喷射发动机的双燃料供应的装置，具有向主燃料喷射器（2）中的每一个提供主喷射器控制信号（8）的电子发动机管理系统（1），该装置包括模拟器主选择器的电特性，当选择替代模式时将主喷射器控制信号（8）从主注射器（2）切换到仿真器（11）的燃料控制开关（10）监视主喷射器控制信号（8）以产生监视信号;以及控制器（4），其处理监视信号以导出替代控制信号，该控制信号用于控制主要燃料供应或主要燃料和二次燃料如LPG，发动机。优选地，主燃料供应通过控制喷射器控制脉冲来调制。辅助燃料也可以被注入（3）并由控制器（4）控制。

6. 发明申请

WO2004064950A1 SPACER FOR SNOWBOARD 审中-公开
标题翻译：雪板间隔
公开(公告)号：WO2004064950A1
公开(公告)日：2004-08-05
申请号：PCT/CH2004/000035
申请日：2004-01-23
申请人： DAKUGA HOLDING LTD. , KUNZ, Jürg , MARTIN, Peter
发明人： KUNZ, Jürg , MARTIN, Peter
IPC分类号： A63C9/00
CPC分类号： A63C10/26 , A63C10/14 , A63C10/18 , A63C10/20 , A63C10/285
摘要： The invention is directed to an improved spacer (1) with at least one centre part (2) and at least one lateral part (3) comprising at least two different materials. The at least one lateral part serves as a load transfer and distribution mean between one of a tip or a heel of a snowboard boot (40) and a snowboard (20).
摘要翻译：本发明涉及具有至少一个中心部分（2）和包括至少两种不同材料的至少一个侧部（3）的改进的间隔物（1）。所述至少一个侧部用作在滑雪板靴（40）和滑雪板（20）的尖端或跟部中的一个之间的载荷传递和分布平均值。

7. 发明申请

WO2004005927A1 METHOD FOR DISCRIMINATION OF METAPLASIAS FROM NEOPLASTIC OR PRENEOPLASTIC LESIONS 审中-公开
标题翻译：用于从嗜酸性或原生态分离物中分离出蛋白质的方法
公开(公告)号：WO2004005927A1
公开(公告)日：2004-01-15
申请号：PCT/EP2003/050096
申请日：2003-04-08
申请人： MTM LABORATORIES AG , MARTIN, Peter
发明人： MARTIN, Peter
IPC分类号： G01N33/574
CPC分类号： C12Q1/6886 , C12Q1/708 , C12Q2600/112 , C12Q2600/158 , G01N33/57411 , G01N2333/025
摘要： The present invention relates to a method for discrimination of p16 INK4a overexpressing metaplasias from neoplastic or preneoplastic p16 INK4a overexpressing lesions by determination of the level of high risk HPV encoded gene-products such as e.g. HPV E2 and/or HPV E7 molecules in biological samples in the course of cytological testing procedures. The method thus enables for reduction of false positive results in the p16 INK4a based detection of anogenital lesions in cytological testing procedures.
摘要翻译：本发明涉及通过测定高危HPV编码基因产物的水平来鉴别过表达p16 过表达p16 过表达病变的p16 的化合物的方法。 HPV E2和/或HPV E7分子在生物样品中的细胞学检测过程中。因此，该方法能够在细胞学检测程序中基于p16 的肛门生成损伤检测中减少假阳性结果。

8. 发明申请

WO2008147882A1 SELF-LOCKING CYLINDER LOCK 审中-公开
标题翻译：自锁式气缸锁
公开(公告)号：WO2008147882A1
公开(公告)日：2008-12-04
申请号：PCT/US2008/064525
申请日：2008-05-22
申请人： CHATEAU PRODUCTS, INC. , MARTIN, Peter
发明人： MARTIN, Peter
IPC分类号： E05B29/04 , E05B29/00 , E05B27/00
CPC分类号： E05B27/083 , E05B9/04 , E05B67/36 , Y10T70/7684
摘要： A self-locking removable plug cylinder lock not requiring a key for the lock to be inserted into a latch aperture and secured in a locked position is provided. The lock includes a cylindrical tumbler-key plug and a locking pin positioned in a generally normal direction to an axial axis of the tumbler-key plug. The locking pin is operable to move in a generally radial inward direction without the use of a key when the plug lock is inserted into a latch aperture.
摘要翻译：提供了一种不需要用于将锁的钥匙插入闩锁孔并固定在锁定位置的自锁可拆卸插塞圆柱锁。该锁包括一个圆柱形的翻转开关插头和一个锁定销，该锁定销位于与转鼓钥匙插头的轴向方向大致正交的方向上。当插头锁插入闩锁孔时，锁定销可操作以在大致径向向内的方向上移动而不使用钥匙。

9. 发明申请

WO2005088311A1 METHOD FOR DETECTING NEOPLASTIC DISORDERS IN A SOLUBILIZED BODY SAMPLE 审中-公开
标题翻译：用于检测溶解性身体样品中的神经障碍的方法
公开(公告)号：WO2005088311A1
公开(公告)日：2005-09-22
申请号：PCT/EP2004/051872
申请日：2004-08-20
申请人： MTM LABORATORIES AG , RIDDER, Ruediger , REICHERT, Anja , VON KNEBEL DOEBERITZ, Magnus , HERKERT, Matthias , DUWE, Alexander , HIPFEL, Rainer , MARTIN, Peter
发明人： RIDDER, Ruediger , REICHERT, Anja , VON KNEBEL DOEBERITZ, Magnus , HERKERT, Matthias , DUWE, Alexander , HIPFEL, Rainer , MARTIN, Peter
IPC分类号： G01N33/574
CPC分类号： G01N33/57484 , G01N33/57411 , Y10T436/25
摘要： The present invention relates to a method for the early diagnosis of neoplastic disorders such as cancers as well as their precursor stages, particularly cancers of the respiratory tract, the urinary system, the reproductive tract, cancer associated with HPV infection or cancer of the anogenital tract, from solubilized body samples. The development of the kits and in-vitro diagnostic devices for the above purpose is also one aspect of the present invention.
摘要翻译：本发明涉及一种用于早期诊断肿瘤性疾病如癌症及其前体阶段的方法，特别是呼吸道癌症，泌尿系统，生殖道，与HPV感染有关的癌症或肛门生殖道癌症，来自溶解的身体样品。用于上述目的的试剂盒和体外诊断装置的开发也是本发明的一个方面。

10. 发明申请

WO2011123714A1 SUTURE PASSER SYSTEMS AND METHODS FOR TONGUE OR OTHER TISSUE SUSPENSION AND COMPRESSION 审中-公开
标题翻译：用于穿刺或其他组织悬挂和压缩的接头传呼系统和方法
公开(公告)号：WO2011123714A1
公开(公告)日：2011-10-06
申请号：PCT/US2011/030829
申请日：2011-03-31
申请人： SIESTA MEDICAL, INC. , VAN DER BURG, Erik , MARTIN, Peter , FEEZOR, Chris , HIROTSUKA, Mark , JACKSON, Jasper , CHENG, Christopher, T. , KOLBER, Michael , LISTON, Adam, H.
发明人： VAN DER BURG, Erik , MARTIN, Peter , FEEZOR, Chris , HIROTSUKA, Mark , JACKSON, Jasper , CHENG, Christopher, T. , KOLBER, Michael , LISTON, Adam, H.
IPC分类号： A61B17/06
CPC分类号： A61B17/0483 , A61B17/0401 , A61B17/0469 , A61B17/0485 , A61B17/0487 , A61B90/39 , A61B2017/00814 , A61B2017/0414 , A61B2017/044 , A61B2017/0448 , A61B2017/0454 , A61B2017/0461 , A61B2017/0472 , A61B2017/06052 , A61B2017/248 , A61B2090/309 , A61B2090/3966
摘要： Suture passer systems (100, 700) for tissue suspension and tissue compression, and more particularly for tongue suspension, are described. The system can include at least a first elongate tubular body or shaft (102, 702), a needle (104, 704) having a lateral bias carried by the elongate body, and a retrieval element (108, 708) operably connected to the elongate tubular body. The needle can have a substantially straight configuration when located within the elongate tubular body, and be configured to exit an opening at or near a distal end of the elongate tubular body and assume a laterally biased or curved shape to form a path through tissue (200). The needle is configured to carry a suture (105). The retrieval element can be configured to retrieve the suture carried by the needle after the needle has formed a curved or otherwise angled path through tissue. The system can also include one or more bone anchors to secure the suture loops. Methods of placing one or more suture loops into tissue, such as the base of the tongue, are also described.
摘要翻译：描述了用于组织悬浮和组织压缩，更具体地用于舌头悬挂的缝合路径系统（100,700）。所述系统可以包括至少第一细长管状体或轴（102,702），具有由细长主体承载的横向偏置的针（104,704）以及可操作地连接到细长体的回收元件（108,708）管状体。当位于细长管状体内时，针可以具有基本上直的构造，并且被配置为离开细长管状体的远端处或附近的开口，并且呈现横向偏置或弯曲形状以形成穿过组织的路径（200 ）。针被配置为携带缝合线（105）。回收元件可以被配置成在针已经形成弯曲的或以其他方式成角度的通过组织的路径之后检索由针承载的缝合线。该系统还可以包括一个或多个骨锚，以固定缝线环。还描述了将一个或多个缝合线环放置到组织中的方法，例如舌的基部。

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