专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2008092854A3 PAPILLOMAVIRUS E2 POLYPEPTIDE USED FOR VACCINATION 审中-公开
标题翻译： PAPILLOMAVIRUS E2多肽用于疫苗接种
公开(公告)号：WO2008092854A3
公开(公告)日：2008-10-30
申请号：PCT/EP2008051032
申请日：2008-01-29
申请人： TRANSGENE SA , BAUDIN MARTINE , BALLOUL JEAN-MARC , SILVESTRE NATHALIE
发明人： BAUDIN MARTINE , BALLOUL JEAN-MARC , SILVESTRE NATHALIE
IPC分类号： C12N15/86 , A61K39/12 , C07K14/025 , C12N7/04 , C12N15/863
CPC分类号： C07K14/005 , A61K2039/525 , C12N7/00 , C12N2710/20022
摘要： The present invention relates to the use of a nucleic acid molecule encoding at least one papillomavirus E2 polypeptide, or a vector, an infectious viral particle or a composition thereof for the preparation of a drug intended for treating a patient suffering from a persistent papillomavirus infection caused by at least one papillomavirus. The present invention also provides a vector comprising a nucleic acid molecule comprising a first nucleotide sequence encoding a papillomavirus E1 polypeptide and a second nucleotide sequence encoding a papillomavirus E2 polypeptide wherein the 3' portion of the first nucleotide which in the natural context is 100% identical to the 5' portion of the second nucleotide is modified so as to exhibit a percentage of identity between said portions of at most 75%.
摘要翻译：本发明涉及编码至少一种乳头状瘤病毒E2多肽或载体，感染性病毒颗粒或其组合物的核酸分子用于制备用于治疗患有持续性乳头瘤病毒感染的患者的药物的用途由至少一种乳头瘤病毒。本发明还提供了包含核酸分子的载体，所述核酸分子包含编码乳头瘤病毒E1多肽的第一核苷酸序列和编码乳头瘤病毒E2多肽的第二核苷酸序列，其中第一核苷酸的3'部分在天然环境中为100％对第二核苷酸的5'部分进行修饰，以使所述部分之间的同一性百分比至多为75％。

2. 发明申请

WO2007077256B1 AVIAN TELOMERASE REVERSE TRANSCRIPTASE 审中-公开
标题翻译： AVIAN TELOMERASE逆向转录
公开(公告)号：WO2007077256B1
公开(公告)日：2007-10-25
申请号：PCT/EP2007050120
申请日：2007-01-05
申请人： TRANSGENE SA , ERBS PHILIPPE , BALLOUL JEAN-MARC , KAPFER MARINA , SILVESTRE NATHALIE
发明人： ERBS PHILIPPE , BALLOUL JEAN-MARC , KAPFER MARINA , SILVESTRE NATHALIE
IPC分类号： C12N9/12
CPC分类号： C12N9/1276
摘要： The present invention notably relates to novel recombinant telomerase reverse transcriptases, nucleic acid molecules coding them, cells comprising said nucleic acid molecule and use of these cells for the production of substance of interest.
摘要翻译：本发明特别涉及新型重组端粒酶逆转录酶，编码它们的核酸分子，包含所述核酸分子的细胞以及这些细胞用于生产感兴趣的物质的用途。

3. 发明专利

JP2007254474A Pharmaceutical composition for treating papillomavirus tumor and infection 有权
标题翻译：用于治疗肺炎支原体肿瘤和感染的药物组合物
公开(公告)号：JP2007254474A
公开(公告)日：2007-10-04
申请号：JP2007092639
申请日：2007-03-30
申请人： Transgene Sa , トランジェーヌ、ソシエテ、アノニムTransgene S.A.
发明人： BALLOUL JEAN-MARC , BIZOUARNE NADINE , KIENY MARIE PAULE
IPC分类号： A61K39/00 , C12N15/09 , A61K31/00 , A61K31/70 , A61K31/7088 , A61K35/76 , A61K38/00 , A61K39/12 , A61K39/385 , A61K48/00 , A61P31/00 , A61P31/12 , A61P31/20 , A61P35/00 , C07K14/025 , C07K14/47 , C07K14/55 , C12N15/00 , C12N15/37 , C12R1/92
CPC分类号： C07K14/005 , A61K39/00 , C12N2710/20022 , C12N2710/24143
摘要： PROBLEM TO BE SOLVED: To provide a pharmaceutical composition intended for treatment or prevention of lesions associated with papillomaviruses and more particularly with human papillomaviruses (HPV) types 16, 18, 31, 33 and 45. SOLUTION: The invention relates to the pharmaceutical composition for treating or preventing including a polypeptide comprising a polypeptide from an early region and a polypeptide from a late region of a papillomavirus and optionally having immunostimulatory activity, or combined-with a polypeptide having immunostimulatory activity and a polypeptide from an early or late region of a papillomavirus, or alternatively, a recombinant vector containing inserted DNA fragments encoding the polypeptide combinations. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供旨在治疗或预防与乳头状瘤病毒相关的病变，特别是16,18,31,33和45型人乳头状瘤病毒（HPV）的药物组合物。解决方案：本发明涉及用于治疗或预防包括来自早期区域的多肽的多肽和来自乳头瘤病毒的晚期区域的多肽，并且任选地具有免疫刺激活性，或与具有免疫刺激活性的多肽和来自早期的多肽的组合或乳头瘤病毒的晚期区域，或者替代地，含有编码多肽组合的插入DNA片段的重组载体。版权所有（C）2008，JPO＆INPIT

4. 发明专利

JP2013027397A Avian telomerase reverse transcriptase 审中-公开
标题翻译： AVIAN TELOMERASE逆向转录
公开(公告)号：JP2013027397A
公开(公告)日：2013-02-07
申请号：JP2012198723
申请日：2012-09-10
申请人： Transgene Sa , トランジェーヌ、ソシエテ、アノニムTransgene S.A.
发明人： HERVE PHILIPPE , BALLOUL JEAN-MARC , KAPFER MARINA , SILVESTRE NATHALIE
IPC分类号： C12N15/09 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N7/00 , C12N9/10
CPC分类号： C12N9/1276
摘要： PROBLEM TO BE SOLVED: To provide a novel recombinant telomerase reverse transcriptases, nucleic acid molecules coding them, cells comprising the nucleic acid molecule and use of these cells for the production of substance of interest.SOLUTION: A polypeptide having a specific amino acid sequence and having a TERT activity, and the nucleic acid encoding the polypeptide are disclosed. A method that makes a cell that belongs to Anatidae immortal by the expression of the polypeptide is disclosed. A production method of the substance of interest by using the cell is disclosed. In addition, the use of the cell for the replication of a virus that includes a complementation cassette that enables the proliferation of the defective virus is disclosed.
摘要翻译：要解决的问题：为了提供新的重组端粒酶逆转录酶，编码它们的核酸分子，包含核酸分子的细胞和这些细胞用于产生感兴趣的物质的用途。解决方案：公开了具有特定氨基酸序列并具有TERT活性的多肽和编码该多肽的核酸。公开了通过多肽的表达使得属于不朽的id科的细胞的方法。公开了通过使用电池的感兴趣物质的制备方法。另外，公开了细胞用于复制病毒的应用，该病毒包括能够增加缺陷病毒的互补盒。版权所有（C）2013，JPO＆INPIT

5. 发明专利

JP2010057500A Antitumoral composition based on immunogenic polypeptide with modified cell location 审中-公开
标题翻译：基于具有改良细胞位置的免疫多聚体的抗肿瘤组合物
公开(公告)号：JP2010057500A
公开(公告)日：2010-03-18
申请号：JP2009253035
申请日：2009-11-04
申请人： Transgene Sa , トランジェーヌ、ソシエテ、アノニムTransgene S.A.
发明人： KIENY MARIE-PAULE , BALLOUL JEAN-MARC , BIZOUARNE NADINE
IPC分类号： C12N15/09 , A61K35/76 , A61K38/00 , A61K39/12 , A61P15/08 , A61P31/12 , A61P31/20 , A61P35/00 , A61P37/04 , A61P43/00 , C07K14/025 , C12N7/00
CPC分类号： C12N7/00 , A61K38/00 , C07K14/005 , C07K2319/00 , C12N2710/20022
摘要： PROBLEM TO BE SOLVED: To provide an antitumoral composition containing one or several kinds of immunogenic polypeptides as a therapeutic agent, wherein at least one of the polypeptides is modified so as to have a cell location different from its native location. SOLUTION: There are provided a composition based on a recombinant vector expressing the immunogenic polypeptide, a recombinant vector comprising at least one sequence coding for an immunogenic polypeptide originating from a precocious and/or tardive region of a papilloma virus having a modified location, a viral particle comprising the vector, and therapeutic use of the composition, the recombinant vector and the viral particle. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：待解决的问题：提供含有一种或几种免疫原性多肽作为治疗剂的抗肿瘤组合物，其中至少一种多肽被修饰以具有不同于其天然位置的细胞位置。提供了基于表达免疫原性多肽的重组载体的组合物，重组载体，其包含编码源自具有修饰位置的乳头瘤病毒的早熟和/或迟发性区域的免疫原性多肽的至少一个序列，包含载体的病毒颗粒和组合物，重组载体和病毒颗粒的治疗用途。版权所有（C）2010，JPO＆INPIT

6. 发明专利

JP2002330774A POXVIRUS HAVING TARGETED INFECTION SPECIFICITY 失效
公开(公告)号：JP2002330774A
公开(公告)日：2002-11-19
申请号：JP2001179289
申请日：2001-06-13
申请人： TRANSGENE SA
发明人： BALLOUL JEAN-MARC , PAUL STEPHANE , GEIST MICHEL
IPC分类号： C12N15/09 , A61K35/76 , A61K48/00 , A61P35/00 , C07K1/22 , C12N7/00 , C12N7/01 , C12R1/93
摘要： PROBLEM TO BE SOLVED: To provide poxvirus particles that are very useful in treatment for gene therapy, particularly in prophylaxis and therapy for mammalian cancers. SOLUTION: The objective poxvirus particles have the targeted infection specificity that is given by a heteroligand part that specifically recognizes and binds to the antiligand molecule locating itself on the surface of the target cells on the poxvirus particle surfaces. Further, this invention provide a vector including the nucleotide sequence encoding the chimera polypeptide including the heteroligand part and all of or a part of the surface polypeptides on the natural type poxvirus particles. In addition, this invention relates to a composition including these poxvirus particles or this vector.

7. 发明专利

JP2002320475A POXVIRUS WITH TARGETED INFECTION SPECIFICITY 失效
公开(公告)号：JP2002320475A
公开(公告)日：2002-11-05
申请号：JP2001153216
申请日：2001-04-13
申请人： TRANSGENE SA
发明人： BALLOUL JEAN-MARC , PAUL STEPHANE , GEIST MICHEL
IPC分类号： C12N15/09 , A61K35/76 , A61K38/00 , A61K39/275 , A61K39/285 , A61K47/48 , A61K48/00 , A61P3/10 , A61P31/00 , A61P35/00 , A61P37/00 , A61P43/00 , C07K14/065 , C07K14/07 , C07K14/705 , C07K19/00 , C12N7/00 , C12N7/01 , C12N7/02 , C12N7/04 , C12N15/39 , C12N15/62 , C12N15/63 , C12N15/86 , C12N15/863 , C12N15/869 , C12Q1/70 , C12R1/93
摘要： PROBLEM TO BE SOLVED: To provide a poxviral particle useful for gene therapy, especially prophylaxis or therapy of cancer in a mammal, and use thereof. SOLUTION: Disclosed is a poxviral particle with a targeted infection specificity given by a different kind of ligand portion capable of specifically recognizing and binding an anti-ligand molecule that exists on the surface of the poxvirus particle and localizes on surface of a target cell. Furthermore, a vector containing the different kind of ligand portion and a nucleotide sequence encoding a chimeric polypeptide containing all or a part of a surface polypeptide of a natural poxvirus particle, a composition containing the poxvirus particle or the vector and uses for therapeutic and prophylactic object are disclosed. The invention is very useful in the gene therapy, especially in the prophylaxis or the therapy of the cancer in the mammal.

8. 发明专利

AU2008209759B2 Papillomavirus E2 polypeptide used for vaccination 未知
公开(公告)号：AU2008209759B2
公开(公告)日：2013-03-21
申请号：AU2008209759
申请日：2008-01-29
申请人： TRANSGENE SA
发明人： BAUDIN MARTINE , BALLOUL JEAN-MARC , SILVESTRE NATHALIE
IPC分类号： C12N15/86 , A61K39/12 , C07K14/025 , C12N7/04 , C12N15/863
摘要： The present invention relates to the use of a nucleic acid molecule encoding at least one papillomavirus E2 polypeptide, or a vector, an infectious viral particle or a composition thereof for the preparation of a drug intended for treating a patient suffering from a persistent papillomavirus infection caused by at least one papillomavirus. The present invention also provides a vector comprising a nucleic acid molecule comprising a first nucleotide sequence encoding a papillomavirus E1 polypeptide and a second nucleotide sequence encoding a papillomavirus E2 polypeptide wherein the 3' portion of the first nucleotide which in the natural context is 100% identical to the 5' portion of the second nucleotide is modified so as to exhibit a percentage of identity between said portions of at most 75%.

9. 发明专利

BRPI0806350A2 未知
公开(公告)号：BRPI0806350A2
公开(公告)日：2011-09-06
申请号：BRPI0806350
申请日：2008-01-29
申请人： TRANSGENE SA
发明人： BAUDIN MARTINE , BALLOUL JEAN-MARC , SILVESTRE NATHALIE
IPC分类号： C12N15/86 , A61K39/12 , C07K14/025 , C12N7/04 , C12N15/863
摘要： The present invention provides a vector comprising a nucleic acid molecule encoding a papillomavirus E1 polypeptide and a nucleic acid molecule encoding a papillomavirus E2 polypeptide wherein said E1-encoding nucleic acid molecule and said E2-encoding nucleic acid molecule do not comprise a portion of 40 or more contiguous nucleotides exhibiting a percentage of identity of 75% or greater than 75%. The invention also provides a vector comprising a nucleic acid molecule comprising a first nucleotide sequence encoding a papillomavirus E1 polypeptide and a second nucleotide sequence encoding a papillomavirus E2 polypeptide wherein the 3' portion of the first nucleotide which in the natural context is 100% identical to the 5' portion of the second nucleotide is modified so as to exhibit a percentage of identity between said portions of at most 75%. The present invention further relates to the use of a nucleic acid molecule encoding at least one papillomavirus E2 polypeptide, or a vector, an infectious viral particle or a composition thereof for the preparation of a drug intended for treating a patient suffering from a persistent papillomavirus infection caused by at least one papillomavirus.

10. 发明专利

BRPI0706836A2 未知
公开(公告)号：BRPI0706836A2
公开(公告)日：2011-04-05
申请号：BRPI0706836
申请日：2007-01-05
申请人： TRANSGENE SA
发明人： ERBS PHILIPPE , BALLOUL JEAN-MARC , KAPFER MARINA , SILVESTRE NATHALIE
IPC分类号： C12N9/12
摘要： The present invention notably relates to novel recombinant telomerase reverse transcriptases, nucleic acid molecules coding them, cells comprising said nucleic acid molecule and use of these cells for the production of substance of interest.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式