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    • 3. 发明公开
    • Apparatus and method for determining functions of cells
    • Verfahren und Vorrichtung zur Ermittlung von Zelleigenschaften。
    • EP0337300A2
    • 1989-10-18
    • EP89106075.8
    • 1989-04-06
    • TORAY INDUSTRIES, INC.
    • Ikeda, YasuoSakai, KiyotakaItagaki, IchiroMikami, MasatoNagaoka, Shoji
    • G01N33/48G01N11/14G01N15/02
    • G01N33/48G01N11/14G01N15/0205G01N33/5091G01N2015/0084
    • An apparatus for determining the functioning properties of cells which includes a sample containing chamber (101), a rotor (2) disposed in the chamber (101) and having a conical surface (2a) which faces the inner bottom surface (36a) of the chamber (101) at an angle of not greater than 2°, a ray transmission path (28) from which a ray is projected into a sample of a cell suspension between the rotor (2) and the inner bottom surface (36a), and a transmitted ray detection path (29) from which transmittance from the sample is detected. The optical path length in the sample is not smaller than 1 cm. An adequate shear stress is applied to the sample by adjusting the gap between the rotor (2) and the inner bottom surface (36a) and rotating the rotor (2). A fine response by the cells caused by the applied shear stress, particularly the aggregation of platelets in a platelet suspension, can be accurately and quantitatively determined with a high sensitivity.
    • 一种用于确定电池的功能特性的装置,其包括样品容纳室(101),设置在所述室(101)中的转子(2),并且具有面向所述腔室的内底表面(36a)的锥形表面(2a) (101),角度不大于2°的射线传播路径(28),射线投射到转子(2)和内底表面(36a)之间的细胞悬浮液的样本中,以及 检测来自样品的透射率的透射光线检测路径(29)。 样品中的光程长度不小于1厘米。 通过调节转子(2)和内底表面(36a)之间的间隙并旋转转子(2),对样品施加足够的剪切应力。 可以以高灵敏度精确地和定量地确定由所施加的剪切应力引起的细胞的细小反应,特别是血小板悬浮液中的血小板聚集。