专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2007143001A3 PROJECT MANAGEMENT SYSTEM 审中-公开
公开(公告)号：WO2007143001A3
公开(公告)日：2007-12-13
申请号：PCT/US2007/012792
申请日：2007-05-31
申请人： TOPCODER, INC. , MESSINGER, David , FERNANDEZ-IVERN, Javier , HUGHES, John, M. , HUGHES, Robert , NORMAN, Lorie, Ilene , JEFTS, Anthony
发明人： MESSINGER, David , FERNANDEZ-IVERN, Javier , HUGHES, John, M. , HUGHES, Robert , NORMAN, Lorie, Ilene , JEFTS, Anthony
IPC分类号： G06F9/46
摘要： A production contest management system enables management of workflow and scoring of projects, for example in a production contest environment. A project is divided into "phases." Project managers can specify project phases, and for each phase, required timing and deliverables. For phases that involve a review (e.g., screening, review board, peer review), scorecards used to perform the review may be specified. The scorecards are made accessible electronically to one or more reviewers. The scorecards may be available on-line, or may be downloaded, completed, and then uploaded. Once received, scorecards are tallied. In this way, the management system helps coordinate production of a product that is produced using production competitions. The system allows for simultaneous management of multiple projects and production teams.

2. 发明申请

WO2007127116A3 SYSTEMS AND METHODS FOR CONDUCTING PRODUCTION COMPETITIONS 审中-公开
公开(公告)号：WO2007127116A3
公开(公告)日：2007-11-08
申请号：PCT/US2007/009477
申请日：2007-04-18
申请人： TOPCODER, INC. , HUGHES, John, M. , LYDON, Michael , MESSINGER, David , LUCE, Marybeth , HUGHES, Robert , FERNANDEZ-IVERN, Javier
发明人： HUGHES, John, M. , LYDON, Michael , MESSINGER, David , LUCE, Marybeth , HUGHES, Robert , FERNANDEZ-IVERN, Javier
IPC分类号： G06F19/00
摘要： This invention relates to methods and a system for compensating contestants for participating in development competitions. In one embodiment, a method for compensating contestants for participating in development competitions includes conducting development competitions in which contestants each submit a development, and for each competition evaluating contestants' submissions; based on the evaluation, assigning a score to contestants' submissions, identifying a number of submissions having a score above a threshold value, designating the contestant who submitted a submission having a score above the threshold value that is the highest score to be the winner of that competition, and awarding performance points to contestants who submitted the identified submissions. The method further includes periodically awarding prizes to the contestants who receive the greatest number of performance points during the period.

3. 发明申请

WO2010045298A1 SYSTEM AND METHOD FOR ADVERTISING PLACEMENT AND/OR WEB SITE OPTIMIZATION 审中-公开
标题翻译：用于广告放置和/或网站优化的系统和方法
公开(公告)号：WO2010045298A1
公开(公告)日：2010-04-22
申请号：PCT/US2009/060605
申请日：2009-10-14
申请人： TOPCODER, INC. , HUGHES, John, M. , HUGHES, Robert
发明人： HUGHES, John, M. , HUGHES, Robert
IPC分类号： G06Q30/00
CPC分类号： G06Q30/0243 , G06Q30/02 , G06Q99/00
摘要： In general, in one aspect, a method for web site optimization includes publishing performance statistics of task performers, facilitating selection of task performers for participation in a competition based on the published performance statistics, facilitating optimization by each selected competitors, collecting response to the optimization of each selected competitor, updating the published performance statistics based on the response; and compensating the task performers based on the published performance statistics. In some embodiments, a prize is awarded to the task performer with the best performance. In some embodiments, a competition is conducted for the design of web site content to be optimized.
摘要翻译：一般来说，一方面，一种用于网站优化的方法包括发布任务执行者的绩效统计，便于基于所发布的绩效统计，参与竞争的任务执行者的选择，促进每个选定竞争对手的优化，收集对优化的响应每个选定的竞争对手，根据回应更新公布的绩效统计数据; 并根据已发布的性能统计信息补偿任务执行者。在一些实施例中，以最佳性能奖励给任务执行者。在一些实施例中，针对要优化的网站内容的设计进行竞争。

4. 发明申请

WO2009062087A1 PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES 审中-公开
标题翻译：制备尿嘧啶衍生物的方法
公开(公告)号：WO2009062087A1
公开(公告)日：2009-05-14
申请号：PCT/US2008/082873
申请日：2008-11-07
申请人： NEUROCRINE BIOSCIENCES, INC. , GALLAGHER, Donald , TREIBER, Laszlo , HUGHES, Robert , CAMPOPIANO, Onorato , WANG, Peng , ZHAO, Yuxin , CHOU, Shine , OUELLETTE, Michael , HETTINGER, Donald
发明人： GALLAGHER, Donald , TREIBER, Laszlo , HUGHES, Robert , CAMPOPIANO, Onorato , WANG, Peng , ZHAO, Yuxin , CHOU, Shine , OUELLETTE, Michael , HETTINGER, Donald
IPC分类号： C07D239/54 , C07D239/553
CPC分类号： C07D239/54 , C07D239/553
摘要： The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.
摘要翻译：本发明涉及用于制备结构（VI）的促性腺激素释放激素（GnRH）受体拮抗剂的方法和中间体; 及其立体异构体及其药学上可接受的盐。

5. 发明申请

WO2004046162A3 NON-STEROIDAL FXR AGONISTS 审中-公开
公开(公告)号：WO2004046162A3
公开(公告)日：2004-06-03
申请号：PCT/US2003/036195
申请日：2003-11-14
申请人： THE SCRIPPS RESEARCH INSTITUTE , NICOLAOU, Kyriacos, C. , ROECKER, Anthony, J. , HUGHES, Robert , PFEFFERKORN, Jeffrey, A.
发明人： NICOLAOU, Kyriacos, C. , ROECKER, Anthony, J. , HUGHES, Robert , PFEFFERKORN, Jeffrey, A.
IPC分类号： C07C233/61
摘要： ABSTRACT Potent non-steroidal farnesoid X receptor (FXR) agonists are N-aryl-N-arylmethyl amido and ureido compounds having the chemical structure represented by the following formula (I): INSERT FORMULA wherein E1 is (C1-C8)alkyl, cyclohexyl, 2-furyl, 3-furyl, 2-thienyl, 3-thienyl, phenyl, or NH(C1-C8)alkyl; L1 and L2 are both H, or together form a pi-bond; X1 is C(O), or CH2; Y1 is H, NHZ1, NH(Z2)Z3, or OZ4; aryl moiety A1 is selected from the group of radicals consisting of: INSERT FORMULA A2 and G1 - G11 are as defined in the specification; and T1 and T2 are each independently O, S, NH, or N(C1-C8)alkyl. The FXR agonists are useful as therapeutic agents for the treatment of diseases linked to cholesterol, bile acids, and their metabolism and homeostasis.

6. 发明申请

WO2010045085A1 SYSTEMS AND METHODS FOR PREDILUTION OF SWEETENER 审中-公开
标题翻译： SWEETENER预测系统与方法
公开(公告)号：WO2010045085A1
公开(公告)日：2010-04-22
申请号：PCT/US2009/059937
申请日：2009-10-08
申请人： THE COCA-COLA COMPANY , ZIESEL, Lawrence, B. , CARPENTER, Gregg , HUGHES, Robert , QUARTARONE, Daniel, S.
发明人： ZIESEL, Lawrence, B. , CARPENTER, Gregg , HUGHES, Robert , QUARTARONE, Daniel, S.
IPC分类号： B67D7/74
CPC分类号： B67D1/07 , B67D1/0021 , B67D1/0043 , B67D1/0044 , B67D1/0857
摘要： A beverage dispensing system using a sweetener. The beverage dispensing system may include a dispensing nozzle, a sweetener source with the sweetener at more than about 65° brix, a first diluent source with a first diluent, a mixing chamber in communication with the sweetener source and the first diluent source so as to dilute the sweetener to less than about 65° brix, and a second diluent source with a second diluent so as to dilute further the sweetener upstream of the dispensing nozzle.
摘要翻译：一种使用甜味剂的饮料分配系统。饮料分配系统可以包括分配喷嘴，甜味剂源，其甜味剂具有大于约65°的白利糖度，具有第一稀释剂的第一稀释剂源，与甜味剂源和第一稀释剂源连通的混合室，将甜味剂稀释至小于约65°白利糖度，并用第二稀释剂稀释第二稀释剂源，以便在分配喷嘴上游进一步稀释甜味剂。

7. 发明申请

WO2004024081A2 ACETYL 2-HYDROXY-1,3 DIAMINOALKANES 审中-公开
标题翻译：乙炔2-羟基-1,3-二氨基二醇
公开(公告)号：WO2004024081A2
公开(公告)日：2004-03-25
申请号：PCT/US2003/028503
申请日：2003-09-10
申请人： ELAN PHARMACEUTICALS, INC. , PFIZER, INC. , MAILLARD, Michel , BALDWIN, Eric, T. , BECK, James, T. , HUGHES, Robert , JOHN, Varghese , PULLEY, Shon, R. , TENBRINK, Ruth
发明人： MAILLARD, Michel , BALDWIN, Eric, T. , BECK, James, T. , HUGHES, Robert , JOHN, Varghese , PULLEY, Shon, R. , TENBRINK, Ruth
IPC分类号： A61K
CPC分类号： C07C233/36 , C07C235/10 , C07C235/74 , C07C271/24 , C07C311/05 , C07C327/30 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2602/10 , C07D209/14 , C07D213/38 , C07D213/64 , C07D215/233 , C07D215/38 , C07D215/42 , C07D215/46 , C07D217/22 , C07D233/61 , C07D233/64 , C07D237/08 , C07D237/14 , C07D239/26 , C07D239/38 , C07D241/12 , C07D249/08 , C07D261/08 , C07D265/02 , C07D277/28 , C07D295/135 , C07D307/52 , C07D309/14 , C07D311/68 , C07D311/74 , C07D333/20 , C07D333/22 , C07D335/06 , C07D405/04 , C07D407/06 , C07D409/12 , C07D495/04
摘要： Disclosed are compounds of the formula: (I) where variables Z, X, R 15 , R 2 , R 3 , and R c are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal.
摘要翻译：公开了式（I）的化合物，其中变量Z，X，R 15，R 2，R 3和R c在本文中定义。本文公开的化合物是β-分泌酶的抑制剂，因此可用于治疗阿尔茨海默氏病和以哺乳动物中Aβ肽沉积为特征的其它疾病。

8. 发明申请

WO2011050215A1 PROCESS FOR PREPARING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR 审中-公开
标题翻译： CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR制备调节剂的方法
公开(公告)号：WO2011050215A1
公开(公告)日：2011-04-28
申请号：PCT/US2010/053628
申请日：2010-10-21
申请人： VERTEX PHARMACEUTICALS INCORPORATED , AMBHAIKAR, Narendra, Bhalchandra , HUGHES, Robert , HURLEY, Dennis, James , LEE, Elaine, Chungmin , LITTLER, Benjamin , NUMA, Mehdi , ROEPER, Stefanie , SHETH, Urvi
发明人： AMBHAIKAR, Narendra, Bhalchandra , HUGHES, Robert , HURLEY, Dennis, James , LEE, Elaine, Chungmin , LITTLER, Benjamin , NUMA, Mehdi , ROEPER, Stefanie , SHETH, Urvi
IPC分类号： C07D215/56 , C07D487/08
CPC分类号： C07D487/08 , C07D215/56
摘要： The present invention relates to processes for preparing solid state forms of N-(4-(7-azabicyclo[2.2. 1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, including Compound 1 Form A, Compound 1 Form A- HCl, Compound 1 Form B, and Compound 1 Form B-HCl, any combination of these forms, pharmaceutical compositions thereof, and methods of treatment therewith.
摘要翻译：本发明涉及制备固体形式的N-（4-（7-氮杂双环[2.2.1]庚-7-基）-2-（三氟甲基）苯基）-4-氧代-5-（三氟甲基） -1,4-二氢喹啉-3-甲酰胺，包括化合物1形式A，化合物1形式A- HCl，化合物1形式B和化合物1形式B-HCl，这些形式的任何组合，其药物组合物，以及治疗。

9. 发明申请

WO2011035139A1 PROCESS FOR PREPARING AZABICYCLIC COMPOUNDS 审中-公开
标题翻译：制备亚氨基化合物的方法
公开(公告)号：WO2011035139A1
公开(公告)日：2011-03-24
申请号：PCT/US2010/049306
申请日：2010-09-17
申请人： VERTEX PHARMACEUTICALS INCORPORATED , AMBHAIKAR, Narendra, Bhalchandra , BEAR, Brian, Richard , FANNING, Lev, T., D. , HUGHES, Robert , LITTLER, Benjamin
发明人： AMBHAIKAR, Narendra, Bhalchandra , BEAR, Brian, Richard , FANNING, Lev, T., D. , HUGHES, Robert , LITTLER, Benjamin
IPC分类号： C07D487/08
CPC分类号： C07D487/08
摘要： The present invention relates to a process for preparing azabicyclic compounds that are useful intermediates for synthesizing pharmaceutical compounds or salts thereof.
摘要翻译：本发明涉及制备作为合成药物化合物或其盐的有用中间体的氮杂双环化合物的方法。

10. 发明申请

WO2005050573A1 CUSTOMER ADMINISTERED AUTOLOAD 审中-公开
标题翻译：客户管理AUTOLOAD
公开(公告)号：WO2005050573A1
公开(公告)日：2005-06-02
申请号：PCT/US2004/038424
申请日：2004-11-15
申请人： CUBIC CORPORATION , ANDREWS, David, W. , CALLAWAY, Leigh, L. , HUGHES, Robert , YOUNG, Douglas
发明人： ANDREWS, David, W. , CALLAWAY, Leigh, L. , HUGHES, Robert , YOUNG, Douglas
IPC分类号： G07B15/00
CPC分类号： G06Q20/363 , G07B15/00 , G07B15/04 , G07F7/0866 , G07F17/0014
摘要： A system and method for automatically loading a pre-selected value onto a fare card allows a patron to enter or leave a transit system gate without having to add a fare value at a vending machine. The automatic loading provides added convenience and security for the patron. The vehicle for the automatically-loaded value is either a credit card that is pre-authorized for use by the patron, or the patron’s available benefits. The automatic loading process may be utilized to autoload values of benefits only, or to load values from a combination of benefits and credit card transactions. The pre-selected autoload value is loaded onto the fare card at the gate before confirmation that the credit card transaction is authorized. The gate sends a message to a transit central computer that an autoload has occurred. The central computer determines whether benefits are available to fill the request, and forward a request for the difference to a credit processing company.
摘要翻译：用于将预选值自动加载到票价卡上的系统和方法允许顾客进入或离开运输系统门，而不必在自动售货机添加票价。自动加载为顾客提供了更多的便利和安全性。自动加载价值的车辆是预先授权给顾客使用的信用卡或顾客可用的利益。自动加载过程可以用于仅自动加载有益的价值，或者从利益和信用卡交易的组合中加载值。在确认信用卡交易被授权之前，预先选择的自动加载值被加载到门口的票价卡上。门向发送自动加载的中转计算机发送消息。中央计算机确定是否可以获得利益来填补请求，并向信用处理公司转发差额请求。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式