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    • 2. 发明申请
    • ADMINISTRATION OF INSULIN BY JET INJECTION
    • 通过喷射注射胰岛素的管理
    • WO2004041331A1
    • 2004-05-21
    • PCT/US2003/004062
    • 2003-02-12
    • ANTARES PHARMA, INC.PASS, FranklinVELUSSI, Mario
    • PASS, FranklinVELUSSI, Mario
    • A61M5/30
    • A61M5/30
    • The invention relates to a method for minimizing mean blood glucose levels in an insulin dependent patient by administering insulin to the patient in a sufficiently fast manner to provide a difference of 50% or less between high and low blood glucose levels. Advantageously, the insulin is administered to the patient by jet injection and the high and low blood glucose levels differ by an amount that is less than that which would be obtained after injection of insulin by a conventional needle syringe. The invention also relates to a method for reducing mean blood glucose levels in an insulin dependent patient that is receiving insulin through a conventional syringe and needle arrangement. This method provides for administration of the insulin to the patient by jet injection rather than by the syringe by substituting a jet injector for the syringe.
    • 本发明涉及通过以足够快的方式向患者施用胰岛素以在高血糖水平和低血糖水平之间提供50%或更低的差异来最小化胰岛素依赖患者中的平均血糖水平的方法。 有利地,胰岛素通过射流注射施用于患者,并且高血糖和低血糖水平的量小于通过常规针注射器注射胰岛素后获得的量。 本发明还涉及一种通过常规注射器和针装置接收胰岛素的胰岛素依赖患者中降低平均血糖水平的方法。 该方法提供了通过喷射注射而不是通过将注射器替换为注射器的喷射器来向患者施用胰岛素。