专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20160184616A1 HISTOTRIPSY USING VERY SHORT ULTRASOUND PULSES 审中-公开
标题翻译：使用非常短的超声波脉冲的感觉
公开(公告)号：US20160184616A1
公开(公告)日：2016-06-30
申请号：US14911273
申请日：2014-08-22
申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN
发明人： Charles A. CAIN , Adam MAXWELL , Zhen XU , Kuang-Wei LIN
IPC分类号： A61N7/00
CPC分类号： A61N7/00 , A61N2007/0039 , A61N2007/0065
摘要： Apparatus and methods are provided for applying ultrasound pulses into tissue or a medium in which the peak negative pressure (P−) of one or more negative half cycle(s) of the ultrasound pulses exceed(s) an intrinsic threshold of the tissue or medium, to directly form a dense bubble cloud in the tissue or medium without shock-scattering. In one embodiment, a microtripsy method of Histotripsy therapy comprises delivering an ultrasound pulse from an ultrasound therapy transducer into tissue, the ultrasound pulse having at least a portion of a peak negative pressure half-cycle that exceeds an intrinsic threshold in the tissue to produce a bubble cloud of at least one bubble in the tissue, and generating a lesion in the tissue with the bubble cloud. The intrinsic threshold can vary depending on the type of tissue to be treated. In some embodiments, the intrinsic threshold in tissue can range from 15-30 MPa.
摘要翻译：提供了用于将超声脉冲施加到组织或介质中的装置和方法，其中超声脉冲的一个或多个负半周的峰值负压（P-）超过组织或介质的固有阈值直接在组织或介质中形成致密的气泡云而不产生冲击散射。在一个实施例中，组织切除术治疗的微切术方法包括将超声脉冲从超声治疗换能器输送到组织中，所述超声脉冲具有超过组织中的固有阈值的至少一部分峰值负压半周期以产生组织中至少有一个气泡的气泡云，并在气泡云中产生组织中的病变。内在阈值可以根据待处理组织的类型而变化。在一些实施方案中，组织中的固有阈值可以在15-30MPa的范围内。

2. 发明申请

US20210008394A1 HISTOTRIPSY USING VERY SHORT ULTRASOUND PULSES 有权
公开(公告)号：US20210008394A1
公开(公告)日：2021-01-14
申请号：US17008369
申请日：2020-08-31
申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN
发明人： Charles A. CAIN , Adam MAXWELL , Zhen XU , Kuang-Wei LIN
IPC分类号： A61N7/00
摘要： Apparatus and methods are provided for applying ultrasound pulses into tissue or a medium in which the peak negative pressure (P−) of one or more negative half cycle(s) of the ultrasound pulses exceed(s) an intrinsic threshold of the tissue or medium, to directly form a dense bubble cloud in the tissue or medium without shock-scattering. In one embodiment, a microtripsy method of Histotripsy therapy comprises delivering an ultrasound pulse from an ultrasound therapy transducer into tissue, the ultrasound pulse having at least a portion of a peak negative pressure half-cycle that exceeds an intrinsic threshold in the tissue to produce a bubble cloud of at least one bubble in the tissue, and generating a lesion in the tissue with the bubble cloud. The intrinsic threshold can vary depending on the type of tissue to be treated. In some embodiments, the intrinsic threshold in tissue can range from 15-30 MPa.

3. 发明申请

US20140100459A1 BUBBLE-INDUCED COLOR DOPPLER FEEDBACK DURING HISTOTRIPSY 审中-公开
标题翻译：爆炸感染引发的多普勒反应
公开(公告)号：US20140100459A1
公开(公告)日：2014-04-10
申请号：US14046024
申请日：2013-10-04
申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN
发明人： Zhen XU , Ryan M. MILLER , Adam MAXWELL , Charles A. CAIN
IPC分类号： A61B8/08 , A61B17/22
CPC分类号： A61B8/488 , A61B5/0035 , A61B5/0059 , A61B5/0075 , A61B5/4848 , A61B8/54 , A61B8/543 , A61B17/22012 , A61B17/2258 , G01S15/8979 , G01S15/8981 , G01S15/899
摘要： A Histotripsy therapy system is provided that can include any number of features. In some embodiments, the system includes a high voltage power supply, a pulse generator electrically coupled to at least one signal switching amplifier, at least one matching network electrically coupled to the signal switching amplifier(s), and an ultrasound transducer having at least one transducer element. The Histotripsy therapy system can further include an ultrasound Doppler imaging system. The Doppler imaging system and the Histotripsy therapy system can be synchronized to enable color Doppler acquisition of the fractionation of tissue during Histotripsy therapy. Methods of use are also described.
摘要翻译：提供组织切除术治疗系统，其可以包括任何数量的特征。在一些实施例中，系统包括高电压电源，电耦合到至少一个信号切换放大器的脉冲发生器，电耦合到信号切换放大器的至少一个匹配网络，以及具有至少一个换能器元件。组织坏死治疗系统还可以包括超声多普勒成像系统。可以同步多普勒成像系统和组织学检查治疗系统，以便在组织切断治疗期间彩色多普勒获得组织分馏。还描述了使用方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式