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    • 2. 发明申请
    • COATING COMPOSITION AND USES THEREOF
    • 涂料组合物及其用途
    • WO2016142298A1
    • 2016-09-15
    • PCT/EP2016/054679
    • 2016-03-04
    • THE QUEEN'S UNIVERSITY OF BELFAST
    • MCCOY, ColinGORMAN, SeanJONES, DavidCORBETT, DanielIRWIN, Nicola
    • C09D4/06
    • C09D4/06A61L27/34A61L29/085A61L31/10C08F271/02C08L39/06C08L51/00
    • The present invention provides a polymerizable coating composition comprising: (i) 1-vinyl-2-pyrrolidinone (NVP)and 2-hydroxyethyl methacrylate (2-HEMA) for forming a copolymer; (ii) a poly(vinyl pyrrolidone) (PVP) polymer having a molecular weight of at least 500,000 g.mol −1 ; (iii) a co-polymerizable crosslinker for crosslinking the 1-vinyl-2-pyrrolidinone (NVP)and the 2- hydroxyethyl methacrylate (2-HEMA); (iv) a co-polymerizable initiator for initiating co-polymerisation of the 1-vinyl-2-pyrrolidinone (NVP) and 2-hydroxyethyl methacrylate (2-HEMA); (v) a surfactant selected from non-ionic triblock copolymers of ethylene oxide/propylene oxide, nonionic triblock copolymers of poly(propylene oxide) (PPO) and poly(ethylene oxide) (PEO), tetrablock copolymers of PPO and PEO; Triton X-100 and derivatives thereof, polyethylene glycols and derivatives thereof, PEO derivatives of sorbitan monolaurate, and combinations of any two or more thereof; (vi) a solvent, wherein a vinyl component is 1-vinyl-2-pyrrolidinone for forming the copolymer and the PVP polymer, and an acrylate component is 2-hydroxyethyl methacrylate for forming the copolymer; wherein the vinyl and acrylate components are present at a molar ratio of between 10:1 and 1:10; and wherein 20-80% (w/w) of the vinyl componentis PVP polymer.
    • 本发明提供一种可聚合涂层组合物,其包含:(i)形成共聚物的1-乙烯基-2-吡咯烷酮(NVP)和甲基丙烯酸2-羟乙酯(2-HEMA) (ii)分子量至少为500,000g.mol-1的聚(乙烯基吡咯烷酮)(PVP)聚合物; (iii)用于交联1-乙烯基-2-吡咯烷酮(NVP)和甲基丙烯酸2-羟乙酯(2-HEMA)的共聚合交联剂; (iv)用于引发1-乙烯基-2-吡咯烷酮(NVP)和甲基丙烯酸2-羟乙酯(2-HEMA)的共聚合的共聚合引发剂; (v)选自环氧乙烷/环氧丙烷的非离子三嵌段共聚物,聚(环氧丙烷)(PPO)和聚(环氧乙烷)(PEO)的非离子三嵌段共聚物,PPO和PEO的四嵌段共聚物的表面活性剂; Triton X-100及其衍生物,聚乙二醇及其衍生物,山梨糖醇酐单月桂酸酯的PEO衍生物及其任意两种或多种的组合; (vi)溶剂,其中乙烯基组分是形成共聚物的1-乙烯基-2-吡咯烷酮和PVP聚合物,丙烯酸酯组分是用于形成共聚物的甲基丙烯酸2-羟乙酯; 其中乙烯基和丙烯酸酯组分以10:1至1:10的摩尔比存在; 并且其中20-80%(w / w)的乙烯基组分是PVP聚合物。