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1. 发明申请

WO2017184199A1 DELIVERY OF SURFACTANT SOLUBLE AGENT 审中-公开
标题翻译：表面活性剂可溶剂的输送
公开(公告)号：WO2017184199A1
公开(公告)日：2017-10-26
申请号：PCT/US2016/058123
申请日：2016-10-21
申请人： THE PROCTER & GAMBLE COMPANY
发明人： CHANG, Debora, W. , JOHNSON, Eric, Scott , GLENN, Robert, Wayne, Jr. , THOMPSON, Todd, Ryan , CARTER, Michelle, Lynn , EDWARDS, Allison, Lynn , EADS, Charles, David , HERTENSTEIN, Stacy, Renee , CORDER, Jennifer, Anne , DIERSING, Steven, Louis , LI, Jianjun, Justin , PENG, Ruzhan
IPC分类号： A61K8/33 , A61K8/34 , A61K8/37 , A61K8/46 , A61K8/49 , A61Q5/00 , A61Q5/02 , A61Q13/00 , A61Q19/10
摘要： The present invention is directed to a personal care composition comprising from about 14% to about 40% of one or more surfactants; from about 0.1% to about 10% of one or more surfactant soluble agents having a ClogP greater than 3.0; wherein when the personal care composition is diluted to about 1.5% surfactant concentration has a ratio of surfactant diffusion coefficient to soluble agent diffusion coefficient greater than 1.2.
摘要翻译：本发明涉及一种个人护理组合物，其包含约14％至约40％的一种或多种表面活性剂; 约0.1％至约10％的一种或多种ClogP大于3.0的表面活性剂可溶剂; 其中当个人护理组合物稀释至约1.5％时，表面活性剂浓度具有大于1.2的表面活性剂扩散系数与可溶性试剂扩散系数的比率。

2. 发明申请

WO2011028758A2 APPARATUS AND METHODS FOR VISUAL DEMONSTRATION OF DENTAL EROSION ON SIMULATED DENTAL MATERIALS 审中-公开
标题翻译：模拟牙科材料对牙齿腐蚀的视觉演示的装置和方法
公开(公告)号：WO2011028758A2
公开(公告)日：2011-03-10
申请号：PCT/US2010/047455
申请日：2010-09-01
申请人： THE PROCTER & GAMBLE COMPANY , DRAKE, Phillip, Asa , PENG, Ruzhan , DECKNER, George, Endel
发明人： DRAKE, Phillip, Asa , PENG, Ruzhan , DECKNER, George, Endel
IPC分类号： A61K6/033
CPC分类号： G09B23/283 , A61K6/0017 , B05D1/185 , B05D2350/65 , G09B19/0084
摘要： Comparative effectiveness of various oral care products such as dentifrices on preventing dental erosion may be demonstrated using simulated enamel. A substrate is prepared. A mineral layer to simulate dental enamel is nucleated by solution growth on the substrate surface. Alternatively, the mineral layer may be nucleated on a template comprising a self-assembled monolayer formed on a gold layer deposited on the substrate surface. The mineral layer may comprise a homogeneous layer of hydroxyapatite or a thin veneer of hydroxyapatite on a layer of amorphous calcium phosphate. The simulated enamel is then optionally treated with an oral care product and subjected to an acid challenge. The amount of mineral layer remaining after the acid challenge dramatically illustrates the effectiveness or non-effectiveness of the oral care product at preventing dental erosion.
摘要翻译：各种口腔护理产品如洁齿剂对预防牙齿侵蚀的比较效果可以使用模拟搪瓷来证明。制备底物。用于模拟牙釉质的矿物层通过在基材表面上的溶液生长而成核。或者，矿物层可以在包含在沉积在基底表面上的金层上形成的自组装单层的模板上成核。矿物层可以在非晶磷酸钙层上包含羟基磷灰石的均匀层或羟基磷灰石的薄薄单板。然后任选地用口腔护理产品处理模拟的牙釉质并进行酸性攻击。在酸挑战之后残留的矿物层的量显着地说明了口腔护理产品在防止牙齿侵蚀方面的有效性或非效力。

3. 发明公开

EP2473151A2 APPARATUS AND METHODS FOR VISUAL DEMONSTRATION OF DENTAL EROSION ON SIMULATED DENTAL MATERIALS 有权
标题翻译：装置和方法有关模拟牙科材料牙酸蚀视觉呈现
公开(公告)号：EP2473151A2
公开(公告)日：2012-07-11
申请号：EP10752248.4
申请日：2010-09-01
申请人： The Procter & Gamble Company
发明人： DRAKE, Phillip, Asa , PENG, Ruzhan , DECKNER, George, Endel
IPC分类号： A61K6/033
CPC分类号： G09B23/283 , A61K6/0017 , B05D1/185 , B05D2350/65 , G09B19/0084
摘要： Comparative effectiveness of various oral care products such as dentifrices on preventing dental erosion may be demonstrated using simulated enamel A substrate is prepared. A mineral layer to simulate dental enamel is nucleated by solution growth on the substrate surface. Alternatively, the mineral layer may be nucleated on a template comprising a self-assembled monolayer formed on a gold layer deposited on the substrate surface. The mineral layer may comprise a homogeneous layer of hydroxyapatite or a thin veneer of hydroxyapatite on a layer of amorphous calcium phosphate. The simulated enamel is then optionally treated with an oral care product and subjected to an acid challenge. The amount of mineral layer remaining after the acid challenge illustrates the effectiveness or non-effectiveness of the oral care product at preventing dental erosion.
摘要翻译：的各种口腔护理产品比较效果：如关于预防牙侵蚀可使用模拟的釉质甲底物实例阐述洁齿剂制备。模拟牙釉质矿物层是由衬底表面上的溶液生长成核。可替代地，所述矿物层可以在模板包括形成沉积在基板表面上的金层上的自组装单层进行成核。该矿物层可以包括羟基磷灰石的均匀层或羟基磷灰石的无定形磷酸钙的层上的薄单板。该仿釉质然后用在口腔护理制品可选处理并进行酸挑战。后酸挑战剩余矿物层的量示出了在预防牙侵蚀的有效性或口腔护理产品的非有效性。

4. 发明授权

EP2473151B1 APPARATUS AND METHODS FOR VISUAL DEMONSTRATION OF DENTAL EROSION ON SIMULATED DENTAL MATERIALS 有权
标题翻译：用于在模拟牙科材料上可视化演示牙科蚀刻的装置和方法
公开(公告)号：EP2473151B1
公开(公告)日：2017-12-27
申请号：EP10752248.4
申请日：2010-09-01
申请人： The Procter & Gamble Company
发明人： DRAKE, Phillip, Asa , PENG, Ruzhan , DECKNER, George, Endel
IPC分类号： A61K6/00 , G09B23/28 , G09B19/00
CPC分类号： G09B23/283 , A61K6/0017 , B05D1/185 , B05D2350/65 , G09B19/0084

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