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1. 发明申请

WO2011124092A1 LIQUID-ELECTRONIC HYBRID DIVIDER 审中-公开
标题翻译：液电子混合分流器
公开(公告)号：WO2011124092A1
公开(公告)日：2011-10-13
申请号：PCT/CN2011/000622
申请日：2011-04-11
申请人： THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY , WEN, Weijia , WANG, Limu , WANG, Xiang , LI, Shunbo
发明人： WEN, Weijia , WANG, Limu , WANG, Xiang , LI, Shunbo
IPC分类号： H01C10/00 , F15C1/04
CPC分类号： B01L3/502792 , B01L3/502784 , B01L7/52 , B01L2200/143 , B01L2300/0645 , B01L2300/0816 , B01L2400/0427 , B01L2400/0677 , F15C1/003 , F15C1/04 , Y10T137/206
摘要： An electronic-fluidic hybrid divider is provided, which is constructed by a simple planer droplet generation structure, a pair of signal electrodes (30, 31), and a responsive control valve, which is programmed to respond to only certain signal droplets (50), by a basic electronic principle: change of voltage share between impedances. Detected fluidic information is addressed in both electronic and fluidic forms, and a fluidic pathway is well-confined in a simple planar structure(although its control valve is in a second layer), thereby minimizing any fluidic disturbance. Various configurations comprise a plurality of identical structures, which can alter their cumulative functions by re-assignment of required voltage share. The hybrid divider can be assembled into a fluidic universal logic gate, of a simple two-inlet and one-outlet signal channels structure, and switch between sixteen functions by re-assigning voltage share. Complex logic functions can be achieved by a cascaded plurality of identical hybrid dividers, and a different logic function can be achieved by merely re-assigning the voltage share scheme.
摘要翻译：提供了一种电子流体混合分配器，其由简单的平面液滴产生结构，一对信号电极（30,31）和响应控制阀构成，其被编程为仅响应某些信号液滴（50），通过基本电子原理：改变阻抗之间的电压份额。检测到的流体信息以电子和流体形式被解决，并且流体路径被良好地限制在简单的平面结构中（尽管其控制阀处于第二层），从而最小化任何流体扰动。各种配置包括多个相同的结构，其可以通过重新分配所需的电压份额来改变其累积功能。混合分压器可以组装成流体通用逻辑门，具有简单的双入口和单出口信号通道结构，并通过重新分配电压共享在十六个功能之间切换。复杂的逻辑功能可以通过级联的多个相同的混合分频器实现，并且通过仅重新分配电压共享方案可以实现不同的逻辑功能。

2. 发明申请

WO2008076427A3 NAPHTHALENONE COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF 审中-公开
公开(公告)号：WO2008076427A3
公开(公告)日：2008-06-26
申请号：PCT/US2007/025819
申请日：2007-12-17
申请人： AMGEN INC. , ALLEN, Jennifer, R. , BISWAS, Kaustav , BRYAN, Marian, C. , BURLI, Roland , CAO, Guo-Qiang , FROHN, Michael, J. , GOLDEN, Jennifer, E. , MERCEDE, Stephanie , NEIRA, Susana , PETERKIN, Tanya , PICKRELL, Alexander, J. , REED, Anthony , TEGLEY, Christopher, M. , WANG, Xiang
发明人： ALLEN, Jennifer, R. , BISWAS, Kaustav , BRYAN, Marian, C. , BURLI, Roland , CAO, Guo-Qiang , FROHN, Michael, J. , GOLDEN, Jennifer, E. , MERCEDE, Stephanie , NEIRA, Susana , PETERKIN, Tanya , PICKRELL, Alexander, J. , REED, Anthony , TEGLEY, Christopher, M. , WANG, Xiang
IPC分类号： C07D311/96 , C07C235/82 , C07D213/56 , C07D213/61 , C07D307/94 , C07C237/24 , C07D221/20 , C07D215/48 , C07C59/88 , C07D217/02 , A61K31/352 , A61P9/10
摘要： Compounds of Formula (I) and Formula (II) are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula(I) and Formula (II) have the following structures, where the definitions of the variables are provided herein.

3. 发明申请

WO2009048527A1 SUBSTITUTED BIPHENYL GPR40 MODULATORS 审中-公开
标题翻译：取代的BIPHENYL GPR40调节器
公开(公告)号：WO2009048527A1
公开(公告)日：2009-04-16
申请号：PCT/US2008/011422
申请日：2008-10-03
申请人： AMGEN INC. , KIM, Yong-Jae , BROWN, Sean, P. , CAO, Qiong , DRANSFIELD, Paul, J. , DU, Xiaohui , HOUZE, Jonathan , JIAO, Xian Yun , KOHN, Todd, J. , LAI, Sujen , LI, An-Rong , LIN, Daniel , LUO, Jian , MEDINA, Julio, C. , REAGAN, Jeffrey, D. , PATTAROPONG, Vatee , SCHWARZ, Margrit , SHEN, Wang , SU, Yongli , SWAMINATH, Gayathri , VIMOLRATANA, Marc , WANG, Xiang , XIONG, Yumei , YANG, Li , YU, Ming , ZHANG, Jie , ZHU, Liusheng
发明人： KIM, Yong-Jae , BROWN, Sean, P. , CAO, Qiong , DRANSFIELD, Paul, J. , DU, Xiaohui , HOUZE, Jonathan , JIAO, Xian Yun , KOHN, Todd, J. , LAI, Sujen , LI, An-Rong , LIN, Daniel , LUO, Jian , MEDINA, Julio, C. , REAGAN, Jeffrey, D. , PATTAROPONG, Vatee , SCHWARZ, Margrit , SHEN, Wang , SU, Yongli , SWAMINATH, Gayathri , VIMOLRATANA, Marc , WANG, Xiang , XIONG, Yumei , YANG, Li , YU, Ming , ZHANG, Jie , ZHU, Liusheng
IPC分类号： C07C59/68 , C07C217/54 , C07C323/19 , C07D213/64 , A61K31/192 , A61K31/4415 , A61P3/10
CPC分类号： C07C323/62 , C07C59/68 , C07C59/72 , C07C217/54 , C07C217/62 , C07C317/22 , C07C323/19 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2601/16 , C07C2601/18 , C07C2602/42 , C07C2603/74 , C07D213/64 , C07D309/12
摘要： The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I: where the definitions of the variables are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.
摘要翻译：本发明提供了可用于例如治疗受试者的代谢紊乱的化合物。这些化合物具有通式I：其中本文提供变量的定义。本发明还提供了组合物，其包括化合物在制备药物和用于治疗代谢性疾病例如II型糖尿病中的使用方法。

4. 发明申请

WO2014165548A2 INDOLINE ALKALOID COMPOUNDS 审中-公开
标题翻译：吲哚类碱性化合物
公开(公告)号：WO2014165548A2
公开(公告)日：2014-10-09
申请号：PCT/US2014/032585
申请日：2014-04-01
申请人： THE REGENTS OF THE UNIVERISITY OF COLORADO, A BODY CORPORATE , WANG, Xiang , PODOLL, Jessica , CHANG, Le
发明人： WANG, Xiang , PODOLL, Jessica , CHANG, Le
IPC分类号： A61K31/4747
CPC分类号： C07D209/86 , A61K31/403 , A61K31/404 , A61K31/407 , A61K31/424 , A61K31/43 , A61K31/437 , A61K31/454 , A61K31/475 , A61K31/546 , A61K45/06 , A61K2300/00
摘要： The present invention relates to indoline alkaloid compounds. In particular, indoline alkaloid compounds of the invention have antibacterial activity and/or are capable of resensitizing the susceptibility of methicillin-resistant S. aureus to a β-lactam antibiotic. The present invention also relates to a method for producing and using the same.
摘要翻译：本发明涉及二氢吲哚生物碱化合物。特别地，本发明的二氢吲哚生物碱化合物具有抗细菌活性和/或能够使耐甲氧西林金黄色葡萄球菌对β-内酰胺抗生素的敏感性敏感。本发明还涉及其制造和使用方法。

5. 发明申请

WO2012052871A1 A WATERPROOF DEVICE 审中-公开
标题翻译：防水设备
公开(公告)号：WO2012052871A1
公开(公告)日：2012-04-26
申请号：PCT/IB2011/054444
申请日：2011-10-10
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , WANG, Xiang , MASON, Martin
发明人： WANG, Xiang , MASON, Martin
IPC分类号： H01M2/10 , H01M2/04 , H05K5/00
CPC分类号： H01M2/1022 , H01M2/0434 , H05K5/061
摘要： This invention provides a device comprising a housing with an opening at its corner, defined by a first and a second sidewall and a top wall, the first sidewall comprising a first slope; a lid to seal the opening, comprising a first, a second, a third and a fourth edge, the first edge comprising a second slope corresponding to the first slope, and the third edge comprising a first tab; a fastening means to fasten the housing and the lid to one another; and a sealing layer to seal the housing and the lid. When the lid is fitted to the housing, retaining forces along 3 orthogonal directions are generated simultaneously.
摘要翻译：本发明提供了一种装置，其包括在其角部处具有由第一和第二侧壁和顶壁限定的开口的壳体，第一侧壁包括第一斜面; 用于密封所述开口的盖，包括第一，第二，第三和第四边缘，所述第一边缘包括对应于所述第一斜面的第二边缘，所述第三边缘包括第一突出部; 紧固装置，用于将壳体和盖子彼此紧固; 以及用于密封壳体和盖子的密封层。当盖子安装到壳体上时，同时产生沿着3个正交方向的保持力。

6. 发明申请

WO2009059281A1 COMPOSITIONS AND METHODS FOR USING CA9 PROTEIN TO STIMULATE AN IMMUNE RESPONSE 审中-公开
标题翻译：使用CA9蛋白刺激免疫应答的组合物和方法
公开(公告)号：WO2009059281A1
公开(公告)日：2009-05-07
申请号：PCT/US2008/082217
申请日：2008-11-03
申请人： HEALTH RESEARCH INC. , KIM, Hyung , WANG, Yanping , WANG, Xiang , SUBJECK, John
发明人： KIM, Hyung , WANG, Yanping , WANG, Xiang , SUBJECK, John
IPC分类号： A61K39/38
CPC分类号： A61K39/0011 , A61K2039/5154 , A61K2039/6031 , A61K2039/6043 , A61K2039/622
摘要： Provided are methods for stimulating an immune response to an antigen by administering a composition to an individual in an amount effective to stimulate an immune response to the antigen. The stimulated immune response to the antigen is greater than the immune response stimulated by the antigen in the absence of CA9 protein. The compositions provided contain a complex that includes an antigen and an isolated CA9 protein.
摘要翻译：提供了通过以有效刺激对抗原的免疫应答的量向个体施用组合物来刺激对抗原的免疫应答的方法。对抗原的刺激免疫应答大于在不存在CA9蛋白时由抗原刺激的免疫应答。提供的组合物含有包含抗原和分离的CA9蛋白的复合物。

7. 发明申请

WO2006029404A1 SYSTEM FOR CONTROL OF STICKIES IN RECOVERED AND VIRGIN PAPER PROCESSING 审中-公开
标题翻译：用于控制恢复和虚拟纸张处理中的纸张的系统
公开(公告)号：WO2006029404A1
公开(公告)日：2006-03-16
申请号：PCT/US2005/032487
申请日：2005-09-08
申请人： ENZYMATIC DEINKING TECHNOLOGIES, LLC , WANG, Xiang , MA, Jianhua , TAUSCHE, James, G.
发明人： WANG, Xiang , MA, Jianhua , TAUSCHE, James, G.
IPC分类号： D21H21/02
CPC分类号： D21H21/02 , D21C9/08 , D21H17/22 , D21H17/45 , D21H17/67 , D21H23/765
摘要： Enhanced removal and/or control of adhesives or sticky materials, "stickies", from recovered paper stock or virgin pulp fibers is achieved using a combination of enzyme treatment with adsorbents and/or absorbents. Pulp stock to be treated is typically obtained from old magazines, newspapers, household waste, but may include corrugated boxes and office waste. Virgin pulps may include mechanical, chemical, or semi-chemical pulps. Enzymes typically include hydrolases such as cellulases, hemicellulases, pectinases, amylases, and lipases such as esterases, lyases such as pectate lyases, and oxidoreductases. Adsorbents include activated bentonite, microparticles, talc, clay and modified silica. Absorbents typically include water soluble polymers, dispersants, coagulatants and agglomerants.
摘要翻译：使用酶处理与吸附剂和/或吸收剂的组合来实现从回收的纸料或原始纸浆纤维中增强粘合剂或粘性材料“粘性”的去除和/或控制。待处理的纸浆通常是从旧杂志，报纸，家庭垃圾中获得的，但可能包括瓦楞纸箱和办公室废物。处女纸可能包括机械，化学或半化学纸浆。酶通常包括水解酶如纤维素酶，半纤维素酶，果胶酶，淀粉酶和脂肪酶如酯酶，裂解酶如果胶酸裂合酶和氧化还原酶。吸附剂包括活性膨润土，微粒，滑石，粘土和改性二氧化硅。吸收剂通常包括水溶性聚合物，分散剂，凝结剂和附聚物。

8. 发明申请

WO2012158418A1 GAS PHASE HETEROGENEOUS CATALYTIC OXIDATION OF ALKANES TO ALIPHATIC KETONES AND/OR OTHER OXYGENATES 审中-公开
标题翻译：气相异构催化氧化氧化烯烃和/或其他氧化剂
公开(公告)号：WO2012158418A1
公开(公告)日：2012-11-22
申请号：PCT/US2012/037033
申请日：2012-05-09
申请人： EVERNU TECHNOLOGY LLC , LIN, Manhua , WANG, Xiang , YEOM, Younghoon
发明人： LIN, Manhua , WANG, Xiang , YEOM, Younghoon
IPC分类号： C07C29/00
CPC分类号： B01J23/28 , B01J21/08 , B01J23/002 , B01J23/30 , B01J23/92 , B01J35/1004 , B01J35/1014 , B01J35/1023 , B01J37/0036 , B01J37/0201 , B01J37/04 , B01J37/08 , B01J38/02 , B01J38/12 , B01J2523/00 , C07C29/50 , C07C45/33 , C07C45/34 , C07C2601/14 , Y02P20/582 , Y02P20/584 , C07C47/02 , C07C49/10 , C07C49/205 , C07C49/403 , B01J2523/15 , B01J2523/27 , B01J2523/68 , B01J2523/12 , B01J2523/3718
摘要： A catalyst, its method of preparation and its use for producing aliphatic ketones by subjecting alkanes C3 to C9 to a gas phase catalytic oxidation in the presence of air or oxygen, and, optionally, steam and / or one or more diluting gases. The catalyst comprises a catalytically active mixed metal oxide phase and a suitable support material onto and / or into which the active catalytic phase is dispersed.
摘要翻译：一种催化剂，其制备方法及其用于通过使烷烃C3至C9在空气或氧气存在下进行气相催化氧化以及任选的蒸汽和/或一种或多种稀释气体来生产脂族酮的用途。催化剂包含催化活性混合金属氧化物相和在其上分散有活性催化相的和/或其中的合适的载体材料。

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