专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2011133617A1 NANO-HYBRID DELIVERY SYSTEM FOR SEQUENTIAL UTILIZATION OF PASSIVE AND ACTIVE TARGETING 审中-公开
标题翻译：用于无源和有源目标的连续使用的纳米混合交付系统
公开(公告)号：WO2011133617A1
公开(公告)日：2011-10-27
申请号：PCT/US2011/033158
申请日：2011-04-20
申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , HONG, Seungpyo , LIU, Ying
发明人： HONG, Seungpyo , LIU, Ying
IPC分类号： A01N25/26 , A61K9/14
CPC分类号： A61K9/127 , A61K9/1273 , A61K9/14 , A61K9/146 , A61K9/5153
摘要： The present invention features nanohybrid drug delivery composition which combines both passive and active targeting for the prevention and treatment of disease. The composition is shell-encapsulated multivalent polymeric scaffold with a therapeutic agent and targeting agent attached thereto.
摘要翻译：本发明的特征在于纳米杂交药物递送组合物，其组合用于预防和治疗疾病的被动和主动靶向。该组合物是具有与其连接的治疗剂和靶向剂的壳包封的多价聚合物支架。

2. 发明申请

WO2010124227A2 METHODS AND DEVICES FOR CAPTURING CIRCULATING TUMOR CELLS 审中-公开
标题翻译：用于捕获循环肿瘤细胞的方法和装置
公开(公告)号：WO2010124227A2
公开(公告)日：2010-10-28
申请号：PCT/US2010/032266
申请日：2010-04-23
申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , HONG, Seungpyo , EDDINGTON, David , MYUNG, Ja Hye , LAUNIERE, Cari
发明人： HONG, Seungpyo , EDDINGTON, David , MYUNG, Ja Hye , LAUNIERE, Cari
IPC分类号： G01N33/574 , G01N33/68 , C12N5/09
CPC分类号： G01N33/574
摘要： A method of capturing a Circulating Tumor Cell (CTC) from a sample includes introducing a sample into a microfluidic device having a cell capture surface and a flow modification surface under conditions that allow a CTC to bind to a cell rolling-inducing agent and a capturing agent disposed on the cell capture surface. The flow modification surface induces a rotational flow within the sample as it flows through the microfluidic device.
摘要翻译：从样品捕获循环肿瘤细胞（CTC）的方法包括将样品引入到具有细胞捕获表面和流动修饰表面的微流体装置中，该条件允许CTC结合细胞转导诱导剂和捕获药剂置于细胞捕获表面上。流动修饰表面在样品流过微流体装置时会引起样品内的旋转流动。

3. 发明申请

WO2012116073A2 AMPHIPHILIC DENDRON-COILS, MICELLES THEREOF AND USES 审中-公开
标题翻译： AMPHIPHILIC DENDRON-COILS，MICELLES THEREOF AND USES
公开(公告)号：WO2012116073A2
公开(公告)日：2012-08-30
申请号：PCT/US2012/026133
申请日：2012-02-22
申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , HONG, Seungpyo , BAE, Jin, Woo
发明人： HONG, Seungpyo , BAE, Jin, Woo
CPC分类号： A61K9/1075 , A61K9/5031 , A61K31/352 , A61K31/405 , A61K47/10 , A61K47/34 , A61K47/44 , C08G63/66 , C08G63/912 , C08G81/00 , C08G83/003 , C08G83/004 , C08G83/008 , C12Q1/02 , G01N33/574
摘要： The invention generally relates to the fields of drug delivery and cell capture. In particular, the invention relates to amphiphilic dendron-coils, micelles thereof and their use for drug delivery vehicles and/or cell capture.
摘要翻译：本发明一般涉及药物递送和细胞捕获的领域。特别地，本发明涉及两亲性树突状线圈，其胶束及其用于药物递送载体和/或细胞捕获的用途。

4. 发明申请

WO2015134972A2 BIOMIMETIC MICROFLUID DEVICE FOR CAPTURING CIRCULATING TUMOR CELLS 审中-公开
标题翻译：用于捕获循环肿瘤细胞的生物微流体装置
公开(公告)号：WO2015134972A2
公开(公告)日：2015-09-11
申请号：PCT/US2015/019466
申请日：2015-03-09
申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
发明人： HONG, Seungpyo , MYUNG, Ja Hye
IPC分类号： G01N33/574
CPC分类号： G01N33/57492 , B01L3/5027 , B01L2300/0636 , B01L2300/0654 , B01L2300/0816 , B01L2300/0861 , B01L2300/0877
摘要： A method of capturing a Circulating Tumor Cell (CTC) and Circulating Cancer Cells (CSC) from a sample includes introducing a sample into a flow based multichannel device having a cell capture surface and a flow modification surface under conditions that allow a CTC to bind to a cell rolling-inducing agent and a capturing agent disposed on the cell capture surface. The invention also provides for flow based multichannel devices to capture CTCs and CSCs from a sample.
摘要翻译：从样品捕获循环肿瘤细胞（CTC）和循环癌细胞（CSC）的方法包括将样品引入具有细胞捕获表面和流动修饰表面的基于流的多通道装置中，所述条件允许CTC结合细胞转导诱导剂和设置在细胞捕获表面上的捕获剂。本发明还提供了用于从样品捕获CTC和CSC的基于流的多通道装置。

5. 发明申请

WO2016183270A1 METHOD FOR MONITORING EFFICACY OF A CANCER THERAPY USING CIRCULATING TUMOR CELLS AS A BIOMARKER 审中-公开
标题翻译：使用循环肿瘤细胞作为生物标志物监测癌症治疗效果的方法
公开(公告)号：WO2016183270A1
公开(公告)日：2016-11-17
申请号：PCT/US2016/031982
申请日：2016-05-12
申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
发明人： WANG, Andrew , EBLAN, Michael , HONG, Seungpyo , MYUNG, Ja, Hye
IPC分类号： A61N5/10 , G01N33/566 , G01N33/574
CPC分类号： G01N33/57488 , A61N5/10 , G01N33/56966 , G01N2800/52
摘要： Methods for monitoring efficacy of cancer therapies, e.g. , radiation therapy, using circulating tumor cell kinetics as a predictive marker are described.
摘要翻译：描述了使用循环肿瘤细胞动力学作为预测标记来监测癌症疗法，例如放射疗法的功效的方法。

6. 发明授权

EP2678042B1 AMPHIPHILIC DENDRON-COILS, MICELLES THEREOF AND USES 有权
标题翻译：两性绦虫线圈，胶束及其用途
公开(公告)号：EP2678042B1
公开(公告)日：2018-05-09
申请号：EP12749426.8
申请日：2012-02-22
申请人： The Board of Trustees of the University of Illinois
发明人： HONG, Seungpyo , BAE, Jin, Woo
IPC分类号： A61K47/50
CPC分类号： A61K9/1075 , A61K9/5031 , A61K31/352 , A61K31/405 , A61K47/10 , A61K47/34 , A61K47/44 , C08G63/66 , C08G63/912 , C08G81/00 , C08G83/003 , C08G83/004 , C08G83/008 , C12Q1/02 , G01N33/574
摘要： The invention generally relates to the fields of drug delivery and cell capture. In particular, the invention relates to amphiphilic dendron-coils, micelles thereof and their use for drug delivery vehicles and/or cell capture.

7. 发明公开

EP3114484A2 BIOMIMETIC MICROFLUID DEVICE FOR CAPTURING CIRCULATING TUMOR CELLS 审中-公开
标题翻译：生物化学药物氟康唑
公开(公告)号：EP3114484A2
公开(公告)日：2017-01-11
申请号：EP15759126.4
申请日：2015-03-09
申请人： The Board of Trustees of the University of Illinois
发明人： HONG, Seungpyo , MYUNG, Ja Hye
IPC分类号： G01N33/574
CPC分类号： G01N33/57492 , B01L3/5027 , B01L2300/0636 , B01L2300/0654 , B01L2300/0816 , B01L2300/0861 , B01L2300/0877
摘要： A method of capturing a Circulating Tumor Cell (CTC) and Circulating Cancer Cells (CSC) from a sample includes introducing a sample into a flow based multichannel device having a cell capture surface and a flow modification surface under conditions that allow a CTC to bind to a cell rolling-inducing agent and a capturing agent disposed on the cell capture surface. The invention also provides for flow based multichannel devices to capture CTCs and CSCs from a sample.
摘要翻译：从样品中捕获循环肿瘤细胞（CTC）和循环癌细胞（CSC）的方法包括将样品引入具有细胞捕获表面和流动修饰表面的基于流的多通道装置中，所述条件允许CTC结合细胞滚动诱导剂和设置在细胞捕获表面上的捕获剂。本发明还提供了用于从样品捕获CTC和CSC的基于流的多通道装置。

8. 发明公开

EP2678042A2 AMPHIPHILIC DENDRON-COILS, MICELLES THEREOF AND USES 有权
标题翻译：两亲DENDRON COIL，胶束ORDER及其用途
公开(公告)号：EP2678042A2
公开(公告)日：2014-01-01
申请号：EP12749426.8
申请日：2012-02-22
申请人： The Board of Trustees of the University of Illinois
发明人： HONG, Seungpyo , BAE, Jin, Woo
IPC分类号： A61K47/48 , A61K47/30 , A61K9/127 , A61P35/00
CPC分类号： A61K9/1075 , A61K9/5031 , A61K31/352 , A61K31/405 , A61K47/10 , A61K47/34 , A61K47/44 , C08G63/66 , C08G63/912 , C08G81/00 , C08G83/003 , C08G83/004 , C08G83/008 , C12Q1/02 , G01N33/574
摘要： The invention generally relates to the fields of drug delivery and cell capture. In particular, the invention relates to amphiphilic dendron-coils, micelles thereof and their use for drug delivery vehicles and/or cell capture.

9. 发明申请

WO2010044509A1 MOTION TRACKING METHOD USING SCANNING DEVICE 审中-公开
标题翻译：使用扫描设备的运动跟踪方法
公开(公告)号：WO2010044509A1
公开(公告)日：2010-04-22
申请号：PCT/KR2008/006881
申请日：2008-11-21
申请人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , KIM, Jinwook , HONG, Seungpyo , KO, Heedong
发明人： KIM, Jinwook , HONG, Seungpyo , KO, Heedong
IPC分类号： H04N1/04 , H04N5/00
CPC分类号： G01S17/66
摘要： The motion tracking method disclosed herein suggests a method for precisely tracking the motion of a scanning device by correcting the surrounding information distortedly recognized due to the time differences between pieces of information regarding the surroundings of the device over one scanning cycle. The method, as a motion tracking method of a scanning device collecting the surrounding information corresponding to a plurality of the points of the surroundings, includes collecting the surrounding information, obtaining the displacement data of the scanning device using the surrounding information, updating the velocity of the scanning device using the displacement data of the scanning device, correcting the surrounding information using the updated velocity of the scanning device, and determining location and position information of the scanning device using the corrected surrounding information. According to the method herein, the motion of the scanning device may be more precisely tracked because the surrounding information is corrected based on the velocity of the scanning device.
摘要翻译：本文公开的运动跟踪方法提出了一种通过校正由于在一个扫描周期上与设备的周围环境相关的信息之间的时间差异而失真识别的周围信息来精确跟踪扫描设备的运动的方法。作为收集与周围的多个点对应的周围信息的扫描装置的运动跟踪方法，包括收集周围信息，使用周围信息获取扫描装置的位移数据，更新速度所述扫描装置使用所述扫描装置的位移数据，使用所述扫描装置的更新速度来校正所述周围信息，以及使用所述校正的周围信息来确定所述扫描装置的位置和位置信息。根据本文的方法，可以更精确地跟踪扫描装置的运动，因为基于扫描装置的速度来校正周围的信息。

10. 发明申请

WO2009043057A2 CELL ROLLING SEPARATION 审中-公开
标题翻译：细胞滚动分离
公开(公告)号：WO2009043057A2
公开(公告)日：2009-04-02
申请号：PCT/US2008/078204
申请日：2008-09-29
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY , KARNIK, Rohit, Nandkumar , HONG, Seungpyo , MEI, Ying , ANDERSON, Daniel, Griffith , KARP, Jeffrey, Michael , LANGER, Robert, S. , BOSE, Suman
发明人： KARNIK, Rohit, Nandkumar , HONG, Seungpyo , MEI, Ying , ANDERSON, Daniel, Griffith , KARP, Jeffrey, Michael , LANGER, Robert, S. , BOSE, Suman
IPC分类号： C12N5/08 , C07K16/28
CPC分类号： C12N5/0068 , B01L3/502715 , B01L3/502761 , B01L2200/0647 , B01L2300/0877 , B01L2300/16 , C12M23/16 , C12M47/02 , C12N5/0062 , C12N2501/58 , C12N2501/585 , C12N2533/50 , C12N2533/52 , C12N2535/10
摘要： The present invention provides systems for cell separation based on cell rolling on surfaces along edges of regions coated with cell adhesion molecules. A variety of designs of coated regions and edges are disclosed.
摘要翻译：本发明提供了基于在细胞粘附分子包被的区域的边缘上的表面上的细胞滚动的细胞分离系统。公开了涂覆区域和边缘的各种设计。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式