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1. 发明公开

EP1242066A4 USE OF 1-AMINOINDAN DERIVATIVES FOR TREATMENT OF MANIA IN BIPOLAR MOOD DISORDER 有权
标题翻译： 1至AMINOINDANDERIVATEN BAHANDLUNG躁狂症使用与双相型障碍
公开(公告)号：EP1242066A4
公开(公告)日：2004-09-01
申请号：EP00976661
申请日：2000-10-27
申请人： TEVA PHARMA
发明人： BARAK GABRIELA , LEVY RUTH
IPC分类号： A61P25/18 , A61K31/16 , A61K31/165 , A61K31/166 , A61K31/198
CPC分类号： A61K31/166 , A61K31/16 , A61K31/165

2. 发明专利

CA2387394A1 USE OF 1-AMINOINDAN DERIVATIVES FOR TREATMENT OF MANIA IN BIPOLAR MOOD DISORDER 未知
公开(公告)号：CA2387394A1
公开(公告)日：2001-05-03
申请号：CA2387394
申请日：2000-10-27
申请人： TEVA PHARMA
发明人： LEVY RUTH , BARAK GABRIELA
IPC分类号： A61P25/18 , A61K31/16 , A61K31/165 , A61K31/166 , A61K31/198
摘要： The subject invention provides a method of treating mania in bipolar disorde r in a subject comprising administering to the subject a therapeutically effective amount of derivatives of 1-aminoindan or their racemic mixtures, enantiomers, or salts, of general formula (I).

3. 发明专利

DE60029131D1 未知
公开(公告)号：DE60029131D1
公开(公告)日：2006-08-10
申请号：DE60029131
申请日：2000-10-27
申请人： TEVA PHARMA
发明人： BARAK GABRIELA , LEVY RUTH
IPC分类号： A61K31/16 , A61P25/18 , A61K31/165 , A61K31/166 , A61K31/198
摘要： The subject invention provides a method of treating mania in bipolar disorder in a subject comprising administering to the subject a therapeutically effective amount of derivatives of 1-aminoindan or their racemic mixtures, enantiomers, or salts, of the general formula:wherein n is 0 or 1;each of R1 and R2 are hydrogen, C1-C4 alkyl, halogen;R3 is hydrogen, C1-C4 alkyl, hydroxy, C1-C4 alkoxy;R4 is hydrogen, C1-C4 alkyl;R6 is hydrogen, substituted or unsubstituted C1-C12 alkyl, C6-C12 aryl, C7-C12 aralkyl or A-N-R9R10, provided that R6 is not methyl when R1, R2, R3 and R4 are hydrogen atoms,wherein A is substituted or unsubstituted C1-C12 alkyl, substituted or unsubstituted C6-C12 aryl, substituted or unsubstituted C7-C12 aralkyl, and each of R9 and R10 are independently hydrogen, C1-C12 alkyl, C6-C12 aryl, C7-C12 aralkyl, COOtBu, or indanyl;and racemic mixtures, enantiomers, and salts thereof.

4. 发明专利

AT331508T 未知
公开(公告)号：AT331508T
公开(公告)日：2006-07-15
申请号：AT00976661
申请日：2000-10-27
申请人： TEVA PHARMA
发明人： BARAK GABRIELA , LEVY RUTH
IPC分类号： A61P25/18 , A61K31/16 , A61K31/165 , A61K31/166 , A61K31/198
摘要： The subject invention provides a method of treating mania in bipolar disorder in a subject comprising administering to the subject a therapeutically effective amount of derivatives of 1-aminoindan or their racemic mixtures, enantiomers, or salts, of the general formula:wherein n is 0 or 1;each of R1 and R2 are hydrogen, C1-C4 alkyl, halogen;R3 is hydrogen, C1-C4 alkyl, hydroxy, C1-C4 alkoxy;R4 is hydrogen, C1-C4 alkyl;R6 is hydrogen, substituted or unsubstituted C1-C12 alkyl, C6-C12 aryl, C7-C12 aralkyl or A-N-R9R10, provided that R6 is not methyl when R1, R2, R3 and R4 are hydrogen atoms,wherein A is substituted or unsubstituted C1-C12 alkyl, substituted or unsubstituted C6-C12 aryl, substituted or unsubstituted C7-C12 aralkyl, and each of R9 and R10 are independently hydrogen, C1-C12 alkyl, C6-C12 aryl, C7-C12 aralkyl, COOtBu, or indanyl;and racemic mixtures, enantiomers, and salts thereof.

5. 发明专利

CA2387394C USE OF 1-AMINOINDAN DERIVATIVES FOR TREATMENT OF MANIA IN BIPOLAR MOOD DISORDER 未知
公开(公告)号：CA2387394C
公开(公告)日：2009-08-18
申请号：CA2387394
申请日：2000-10-27
申请人： TEVA PHARMA
发明人： BARAK GABRIELA , LEVY RUTH
IPC分类号： A61K31/165 , A61P25/18 , A61K31/16 , A61K31/166 , A61K31/198
摘要： The subject invention provides a method of treating mania in bipolar disorder in a subject comprising administering to the subject a therapeutically effective amount of derivatives of 1-aminoindan or their racemic mixtures, enantiomers, or salts, of general formula (I).

6. 发明专利

DE60029131T2 未知
公开(公告)号：DE60029131T2
公开(公告)日：2007-01-18
申请号：DE60029131
申请日：2000-10-27
申请人： TEVA PHARMA
发明人： BARAK GABRIELA , LEVY RUTH
IPC分类号： A61K31/16 , A61P25/18 , A61K31/165 , A61K31/166 , A61K31/198
摘要： The subject invention provides a method of treating mania in bipolar disorder in a subject comprising administering to the subject a therapeutically effective amount of derivatives of 1-aminoindan or their racemic mixtures, enantiomers, or salts, of the general formula:wherein n is 0 or 1;each of R1 and R2 are hydrogen, C1-C4 alkyl, halogen;R3 is hydrogen, C1-C4 alkyl, hydroxy, C1-C4 alkoxy;R4 is hydrogen, C1-C4 alkyl;R6 is hydrogen, substituted or unsubstituted C1-C12 alkyl, C6-C12 aryl, C7-C12 aralkyl or A-N-R9R10, provided that R6 is not methyl when R1, R2, R3 and R4 are hydrogen atoms,wherein A is substituted or unsubstituted C1-C12 alkyl, substituted or unsubstituted C6-C12 aryl, substituted or unsubstituted C7-C12 aralkyl, and each of R9 and R10 are independently hydrogen, C1-C12 alkyl, C6-C12 aryl, C7-C12 aralkyl, COOtBu, or indanyl;and racemic mixtures, enantiomers, and salts thereof.

7. 发明专利

AU775885B2 Use of 1-aminoindan derivatives for treatment of mania in bipolar mood disorder 未知
公开(公告)号：AU775885B2
公开(公告)日：2004-08-19
申请号：AU1440201
申请日：2000-10-27
申请人： TEVA PHARMA
发明人： BARAK GABRIELA , LEVY RUTH
IPC分类号： A61P25/18 , A61K31/16 , A61K31/165 , A61K31/166 , A61K31/198
摘要： The subject invention provides a method of treating mania in bipolar disorder in a subject comprising administering to the subject a therapeutically effective amount of derivatives of 1-aminoindan or their racemic mixtures, enantiomers, or salts, of the general formula:wherein n is 0 or 1;each of R1 and R2 are hydrogen, C1-C4 alkyl, halogen;R3 is hydrogen, C1-C4 alkyl, hydroxy, C1-C4 alkoxy;R4 is hydrogen, C1-C4 alkyl;R6 is hydrogen, substituted or unsubstituted C1-C12 alkyl, C6-C12 aryl, C7-C12 aralkyl or A-N-R9R10, provided that R6 is not methyl when R1, R2, R3 and R4 are hydrogen atoms,wherein A is substituted or unsubstituted C1-C12 alkyl, substituted or unsubstituted C6-C12 aryl, substituted or unsubstituted C7-C12 aralkyl, and each of R9 and R10 are independently hydrogen, C1-C12 alkyl, C6-C12 aryl, C7-C12 aralkyl, COOtBu, or indanyl;and racemic mixtures, enantiomers, and salts thereof.

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