专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2002033111A3 NUCLEIC ACID CONSTRUCTS AND CELLS, AND METHODS UTILIZING SAME FOR MODIFYING THE ELECTROPHYSIOLOGICAL FUNCTION OF EXCITABLE TISSUES 审中-公开
公开(公告)号：WO2002033111A3
公开(公告)日：2002-04-25
申请号：PCT/IL2001/000833
申请日：2001-09-05
申请人： TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. , FELD, Yair , GEPSTEIN, Lior , MAROM, Shimon , FRANK, Meira
发明人： FELD, Yair , GEPSTEIN, Lior , MAROM, Shimon , FRANK, Meira
IPC分类号： C07H21/04
摘要： A method of modifying the electrophysiological function of an excitable tissue region of an individual is provided. The method includes the step of implanting cells into the excitable tissue region. Each implanted cell is (a) capable of forming gap junctions with at least one cell of the excitable tissue region; and (b) capable of forming a functional ion channel or transporter, wherein the functional ion channel or transporter is capable of modifying the electrophysiological function of the excitable tissue region.

2. 发明申请

WO2006018836A2 NUCLEIC ACID CONSTRUCTS AND CELLS, AND METHODS UTILIZING SAME FOR MODIFYING THE ELECTROPHYSIOLOGICAL FUNCTION OF EXCITABLE TISSUES 审中-公开
标题翻译：核酸结构和细胞，以及用于修饰可激活组织的电生理功能的方法
公开(公告)号：WO2006018836A2
公开(公告)日：2006-02-23
申请号：PCT/IL2005/000881
申请日：2005-08-15
申请人： GENEGRAFTS LTD. , FELD, Yair , GEPSTEIN, Lior , MAROM, Shimon
发明人： FELD, Yair , GEPSTEIN, Lior , MAROM, Shimon
IPC分类号： A61K48/00 , C07H21/04 , C07K14/705 , C12N5/08
CPC分类号： A61K48/005 , A61K35/12 , C07H21/04
摘要： Polynucleotide expression constructs, populations of cells and methods of treating diseases caused by dysfunction in, or damage to, excitable tissues are provided.
摘要翻译：提供多核苷酸表达构建体，细胞群和治疗由可激活组织的功能障碍或损害引起的疾病的方法。

3. 发明申请

WO2008078325A2 A METHOD OF TREATING SCHIZOPHRENIA 审中-公开
标题翻译：一种治疗精神分裂症的方法
公开(公告)号：WO2008078325A2
公开(公告)日：2008-07-03
申请号：PCT/IL2007/001606
申请日：2007-12-25
申请人： GENEGRAFTS LTD. , MAROM, Shimon , GLUZMAN, Zoya , FELD, Yair
发明人： MAROM, Shimon , GLUZMAN, Zoya , FELD, Yair
IPC分类号： A61K38/17
CPC分类号： A61K35/33
摘要： A method of treating schizophrenia in a subject in need thereof is provided. The method comprising, administering to the subject a therapeutically effective amount of cells expressing at least one exogenous polypeptide forming a connexin channel and/or a hyperpolarizing ion channel, thereby treating the schizophrenia in the subject.
摘要翻译：提供了在有需要的受试者中治疗精神分裂症的方法。该方法包括向受试者施用表达至少一种形成连接蛋白通道和/或超极化离子通道的至少一种外源多肽的细胞，由此治疗受试者中的精神分裂症。

4. 发明申请

WO2007069247A2 POLYNUCLEOTIDES AND POLYPEPTIDE OF HUMAN KV1.3, COMPOSITIONS COMPRISING SAME AND METHODS OF USING SAME 审中-公开
标题翻译：人KV1.3的多核苷酸和多肽，包含其的组合物及其使用方法
公开(公告)号：WO2007069247A2
公开(公告)日：2007-06-21
申请号：PCT/IL2006/001431
申请日：2006-12-12
申请人： GENEGRAFTS LTD. , BRESLER, Tal , FELD, Yair , MAROM, Shimon , MIARI, Reem
发明人： BRESLER, Tal , FELD, Yair , MAROM, Shimon , MIARI, Reem
IPC分类号： A61K48/00 , C07K14/705
CPC分类号： C07K14/705 , A61K38/00
摘要： An isolated polypeptide comprising, contiguously, a first amino acid sequence being at least 90 % homologous to amino acid coordinates 1-398 of SEQ ID NO: 2, a tryptophan residue and a second amino acid sequence being at least 90 % homologous to amino acid coordinates 400-523 of SEQ ID NO:2. Also provided are polynucleotide sequences encoding this polypeptide and uses of same in the treatment of medical conditions associated with ion channel insufficiency.
摘要翻译：分离的多肽，其连续性包含与SEQ ID NO：2的氨基酸坐标1-398至少90％同源的色氨酸残基和与氨基酸至少90％同源的第二氨基酸序列 SEQ ID NO：2的坐标400-523。还提供了编码该多肽的多核苷酸序列及其在治疗与离子通道功能不全相关的医学病症中的用途。

5. 发明申请

WO2020026234A1 TRANSCATHETER ARTIFICIAL CUSP FOR VALVE INSUFFICIENCY 审中-公开
公开(公告)号：WO2020026234A1
公开(公告)日：2020-02-06
申请号：PCT/IL2019/050853
申请日：2019-07-28
申请人： FELD, Yair
发明人： FELD, Yair
IPC分类号： A61F2/06 , A61F2/02 , A61F2/24 , A61F2/82 , A61F2/848 , A61F2/86 , A61F2/90
摘要： The present invention relates to an obstructing device comprising a hollow tubular member comprising a. a proximal opening at its proximal end; b. a substantially tubular surface extending distally from said proximal opening; c. a distal end. The obstructing device further comprises a grasping arm extending distally from said opening at the proximal end; wherein the distal end is either closed or comprises a small orifice. The present invention relates to a method of delivery of said device.

6. 发明申请

WO2003007778A2 IN-VIVO METHOD AND DEVICE FOR IMPROVING DIASTOLIC FUNCTION OF THE LEFT VENTRICLE 审中-公开
标题翻译：用于改善左肝门静脉功能的体内方法和装置
公开(公告)号：WO2003007778A2
公开(公告)日：2003-01-30
申请号：PCT/IL2002/000547
申请日：2002-07-04
申请人： RELAXIS LTD. , FELD, Yair
发明人： FELD, Yair
IPC分类号： A61B
CPC分类号： A61F2/2481 , A61B17/00234 , A61B17/00491 , A61B17/0401 , A61B17/0469 , A61B17/064 , A61B2017/048 , A61F2/2487 , A61F2002/249 , A61F2002/30079 , A61F2210/009
摘要： A method and device featuring at least one component providing a potential to kinetic converted elastic, magnetic repulsion, or, an elastic and magnetic repulsion, pushing, pulling, or, pulling and pushing, type of radially outward expansive force or pressure to an inner, outer, intermediate, and, combination thereof, wall region of the left ventricle, for reducing intraluminal hydrostatic pressure of the left ventricle (LV filling pressure) during the ventricular diastolic stage of the cardiac cycle, thereby, improving diastolic function of the left ventricle of the heart in subjects having a condition of diastolic heart failure (DHF), while minimally disturbing systolic function of the heart. The expansive force or pressure is in a range of about 5 - 20 mm Hg, whereby, left ventricular end diastolic pressure (LVEDP) is reduced down to the normal range of about 6 - 12 mm Hg, during ventricular diastole of the heart.
摘要翻译：一种方法和装置，其特征在于至少一个部件提供动力转换的弹性，磁性排斥，或弹性和磁性排斥，推动，拉动或拉动和推动径向向外的膨胀力或压力的类型到内部，外部，中间和组合的左心室的壁区域，用于在心脏周期的心室舒张期期间降低左心室的腔内静水压（LV填充压力），由此改善左心室舒张功能具有舒张性心力衰竭状况（DHF）的受试者的心脏，同时心脏的收缩功能最小化。膨胀力或压力在约5-20mm Hg的范围内，由此，在心脏心室舒张期间，左心室舒张末期压（LVEDP）降低至约6-12mm Hg的正常范围。

7. 发明申请

WO2015193880A1 CONTINUOUS IMPLANTABLE PERITONEAL DIALYSIS 审中-公开
标题翻译：连续可植入的透析
公开(公告)号：WO2015193880A1
公开(公告)日：2015-12-23
申请号：PCT/IL2015/050598
申请日：2015-06-14
申请人： FELD, Yair
发明人： FELD, Yair
IPC分类号： A61M1/28
CPC分类号： A61M1/285 , A61M1/28 , A61M25/0041 , A61M25/10 , A61M27/008 , A61M2205/04 , A61M2205/75 , A61M2210/1021 , A61M2210/1085
摘要： A system and method for draining excessive fluid from a body cavity or space. The system comprises an implantable fluid penetrable chamber comprising a frame covered by a fluid permeable mesh configured to enable fluids to penetrate therethrough. The system further comprises a catheter connected at a first end to one of said chamber sides/walls or penetrates therethrough; and optionally further comprises a pump placed inside or outside of said chamber.
摘要翻译：用于从体腔或空间排出过量流体的系统和方法。该系统包括可植入液体可渗透腔室，其包括被流体渗透的网状物覆盖的框架，该网眼构造成使得流体能够穿透其中。该系统还包括在第一端连接到所述室侧/壁之一或穿过其中的导管; 并且可选地还包括放置在所述室的内部或外部的泵。

8. 发明申请

WO2006117785A3 METHODS FOR REDUCING HYDROSTATIC ORGAN PRESSURE 审中-公开
公开(公告)号：WO2006117785A3
公开(公告)日：2006-11-09
申请号：PCT/IL2006/000525
申请日：2006-05-04
申请人： FELD, Yair
发明人： FELD, Yair
IPC分类号： A61B19/00 , A61M29/00
摘要： A method for stretching at least a portion of an organ to decrease interstitial hydrostatic pressure and improve at least one organ function. The method comprises providing at least one elastically compressible anchor, compressing the at least one anchor, anchoring the at least one anchor to a portion of an organ from the group of organs consisting of: a kidney, a liver, a bladder, and a stomach. The method further comprises releasing the compressing, thereby stretching the portion and decreasing interstitial hydrostatic pressure.

9. 发明申请

WO2004066805A2 IN VIVO DEVICE FOR IMPROVING DIASTOLIC VENTRICULAR FUNCTION 审中-公开
标题翻译：用于改善腹腔功能的体内器件
公开(公告)号：WO2004066805A2
公开(公告)日：2004-08-12
申请号：PCT/IL2004/000072
申请日：2004-01-26
申请人： CORASSIST CARDIOVASCULAR LTD. , DUBI, Shay , FELD, Yair
发明人： DUBI, Shay , FELD, Yair
IPC分类号： A61B
CPC分类号： A61F2/2481 , A61B17/00234 , A61B17/0401 , A61B2017/00243 , A61B2017/00867 , A61B2017/0441 , A61B2017/0496
摘要： The present invention provides an in vivo device for improving diastolic function of the heart, comprising: at least one elastic component that may be operatively connected to the external surface of the left or right ventricle of the heart by means of connecting elements, wherein said elastic component comprises essentially longitudinal members arranged such that the lateral separation therebetween may be increased or decreased in response to elastic deformation of said elastic component, and wherein said essentially longitudinal members are arranged such that said elastic component is curved in both the vertical and horizontal planes, such that its inner surface may be adapted to the curvature of the external ventricular surface of the heart, such that said elastic component is capable of exerting both radially outward expansive and tangentially-directed forces on the external surface of the cardiac ventricle.
摘要翻译：本发明提供一种用于改善心脏舒张功能的体内装置，包括：至少一个弹性部件，其可通过连接元件与心脏的左心室或右心室的外表面可操作地连接，其中所述弹性组件包括基本纵向构件，其布置成使得它们之间的横向分离可以响应于所述弹性构件的弹性变形而增加或减小，并且其中所述基本上纵向构件布置成使得所述弹性构件在垂直和水平面中均弯曲，使得其内表面可以适应于心脏的外部心室表面的曲率，使得所述弹性部件能够在心室的外表面上施加径向向外的膨胀和切向力。

10. 发明申请

WO2012123950A3 DEVICES FOR URETHRAL TREATMENT 审中-公开
公开(公告)号：WO2012123950A3
公开(公告)日：2012-09-20
申请号：PCT/IL2012/050094
申请日：2012-03-15
申请人： PROARC MEDICAL LTD. , BAR-ON, Raz , SHABAT Roni , GOLAN, Shai , LENGEL, Yoav , FELD, Yair
发明人： BAR-ON, Raz , SHABAT Roni , GOLAN, Shai , LENGEL, Yoav , FELD, Yair
IPC分类号： A61F2/04 , A61B17/3207
摘要： A dilation device (206) for an intra-body lumen, for example, a urethra partially occluded by an enlarged prostate in the form of a resilient curved body configured to be implanted in a cut around the lumen, and a method for dilating such a lumen by implanting a dilation device in a cut around the outside of the lumen. Also, a deployment system (300) including a delivery device for the implant, and a device for dilating the lumen before and while the cut is being made, and a method of using the implant and the deployment system. The implant may be formed of a strip or a coiled wire. The cut may be performed in part by the implant. The cut may be performed by a sharp edge, and/or by application of electrical current to the area being cut, or by a piezoelectric transducer.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式