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1. 发明授权

US06777003B1 Iodine complex of alkyl polyglycosides 失效
标题翻译：烷基多糖苷的碘络合物
公开(公告)号：US06777003B1
公开(公告)日：2004-08-17
申请号：US08482579
申请日：1995-06-07
申请人： Suresh Desai , John Frederick Hessel
发明人： Suresh Desai , John Frederick Hessel
IPC分类号： A01N5912
CPC分类号： A01N59/12 , A01N43/16 , A01N25/30 , A01N2300/00
摘要： An iodine complex concentrate containing (a) from about 0.5 to about 30% by weight of iodine; (b) from about 0.2 to about 14% by weight of an iodide component selected from the group consisting of iodide salt, iodide acid and mixtures thereof; and (c) from about 2% to about 85% by weight of a nonionic sugar surfactant selected from the group consisting of alkyl glucose esters, aldobionamides, gluconamides, glyceramides, glyceroglycolipids, polygydroxy fatty acid amides, alkyl polyglycosides having the general formula I: R1O(R2O)b(Z)a I wherein R1 is a monovalent organic radical having from about 6 to about 30 carbon atoms; R2 is divalent alkylene radical having from 2 to 4 carbon atoms; Z is a saccharide residue having 5 or 6 carbon atoms; b is a number having a value from 0 to about 12; a is a number having a value from 1 to about 6, and mixtures thereof, all weights being based on the weight of the concentrate.
摘要翻译：一种碘络合物浓缩物，其含有（a）约0.5至约30重量％的碘; （b）约0.2至约14重量％的选自碘化物盐，碘酸及其混合物的碘化物组分; 和（c）约2％至约85％重量的选自烷基葡萄糖酯，醛二酰胺，葡糖酰胺，甘油酰胺，甘油糖脂，聚羟基脂肪酸酰胺，具有通式I的烷基多糖苷的非离子糖表面活性剂：其中R 1是具有约6至约30个碳原子的一价有机基团; R2是具有2至4个碳原子的二价亚烷基; Z是具有5或6个碳原子的糖残基; b是0至约12的数值; a是1至约6的数值，以及它们的混合物，所有重量均以浓缩物的重量为基准。

2. 发明授权

US07101683B2 Methods for the simultaneous detection of HCV antigens and HCV antibodies 有权
公开(公告)号：US07101683B2
公开(公告)日：2006-09-05
申请号：US09891983
申请日：2001-06-26
申请人： Dinesh O. Shah , George J. Dawson , Anthony Scott Muerhoff , Xingli Jiang , Robin A. Gutierrez , Thomas P. Leary , Suresh Desai , James L. Stewart
发明人： Dinesh O. Shah , George J. Dawson , Anthony Scott Muerhoff , Xingli Jiang , Robin A. Gutierrez , Thomas P. Leary , Suresh Desai , James L. Stewart
IPC分类号： C11Q1/00 , C12Q1/70 , G01N33/53
CPC分类号： C07K14/005 , C12N2770/24222 , G01N33/5767 , G01N2469/10 , G01N2469/20
摘要： The subject invention relates to methods for the simultaneous detection of Hepatitis C Virus (HCV) antigens as well as antibodies produced in response to HCV antigens. Furthermore, the subject invention allows one to detect antigens in the early, acute stage of infection, even prior to the development of antibodies, thereby allowing for early detection of infected blood and blood products, thus improving the safety of the blood supply.

3. 发明授权

US06727092B2 Methods for the simultaneous detection of HCV antigens and HCV antibodies 有权
标题翻译：同时检测HCV抗原和HCV抗体的方法
公开(公告)号：US06727092B2
公开(公告)日：2004-04-27
申请号：US10173480
申请日：2002-06-17
申请人： Dinesh Shah , George Dawson , A. Scott Muerhoff , Thomas P. Leary , Robin A. Guetierrez , Lily Jiang , Suresh Desai , James L. Stewart
发明人： Dinesh Shah , George Dawson , A. Scott Muerhoff , Thomas P. Leary , Robin A. Guetierrez , Lily Jiang , Suresh Desai , James L. Stewart
IPC分类号： C12N1574
CPC分类号： C07K14/005 , C12N2770/24222 , G01N33/5767 , G01N2469/10 , G01N2469/20
摘要： The subject invention relates to methods for the simultaneous detection of Hepatitis C Virus (HCV) antigens as well as antibodies produced in response to HCV antigens. Furthermore, the subject invention allows one to detect antigens in the early, acute stage of infection, even prior to the development of antibodies, thereby allowing for early detection of infected blood and blood products, thus improving the safety of the blood supply.
摘要翻译：本发明涉及同时检测丙型肝炎病毒（HCV）抗原以及响应HCV抗原产生的抗体的方法。此外，本发明允许在感染的早期，急性期中检测抗原，甚至在抗体发生之前，从而允许早期检测感染的血液和血液制品，从而提高血液供应的安全性。

4. 发明授权

US06855809B2 Methods for the simultaneous detection of HCV antigens and HCV antibodies 有权
标题翻译：同时检测HCV抗原和HCV抗体的方法
公开(公告)号：US06855809B2
公开(公告)日：2005-02-15
申请号：US10753910
申请日：2004-01-07
申请人： Dinesh O. Shah , George J. Dawson , A. Scott Muerhoff , Lily Jiang , Robin A. Gutierrez , Thomas P. Leary , Suresh Desai , James L. Stewart
发明人： Dinesh O. Shah , George J. Dawson , A. Scott Muerhoff , Lily Jiang , Robin A. Gutierrez , Thomas P. Leary , Suresh Desai , James L. Stewart
IPC分类号： G01N33/543 , C07K14/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/04 , G01N21/76 , G01N33/576 , C07K14/00 , A61K39/00 , C07H21/00 , C07K14/08 , C12N15/62
CPC分类号： C07K14/005 , C12N2770/24222 , G01N33/5767 , G01N2469/10 , G01N2469/20
摘要： The subject invention relates to methods for the simultaneous detection of Hepatitis C Virus (HCV) antigens as well as antibodies produced in response to HCV antigens. Furthermore, the subject invention allows one to detect antigens in the early, acute stage of infection, even prior to the development of antibodies, thereby allowing for early detection of infected blood and blood products, thus improving the safety of the blood supply.
摘要翻译：本发明涉及同时检测丙型肝炎病毒（HCV）抗原以及响应HCV抗原产生的抗体的方法。此外，本发明允许在感染的早期，急性期中检测抗原，甚至在抗体发生之前，从而允许早期检测感染的血液和血液制品，从而提高血液供应的安全性。

5. 发明授权

US06395472B1 Methods of utilizing the TT virus 失效
标题翻译： TT病毒的使用方法
公开(公告)号：US06395472B1
公开(公告)日：2002-05-28
申请号：US09245248
申请日：1999-02-05
申请人： Thomas P. Leary , James Erker , Michelle Chalmers , John Simons , Larry Birkenmeyer , Scott Muerhoff , Tami Pilot-Matias , Suresh Desai , Isa Mushahwar
发明人： Thomas P. Leary , James Erker , Michelle Chalmers , John Simons , Larry Birkenmeyer , Scott Muerhoff , Tami Pilot-Matias , Suresh Desai , Isa Mushahwar
IPC分类号： C12Q170
CPC分类号： C12Q1/701 , Y10S977/804
摘要： The present invention relates to nucleic oligomer primers or probes useful for detection of TTV in test samples. Also provided are assays which utilize these primers and probes, as well as test kits which contain these oligomer primers and/or probes. In addition, the present invention encompasses the use of TTV nucleotide sequences as nucleic acid vectors and as markers for determining transmission between individuals as well as the route thereof. Additionally, the present invention encompasses a method of detecting TTV infection prior to xenotransplatation of a tissue or organ.
摘要翻译：本发明涉及用于在测试样品中检测TTV的核酸低聚物引物或探针。还提供了利用这些引物和探针的测定法，以及含有这些寡聚体引物和/或探针的测试试剂盒。此外，本发明包括TTV核苷酸序列作为核酸载体的用途以及用于确定个体间传播的标记及其途径。此外，本发明包括在组织或器官的异种移植之前检测TTV感染的方法。

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