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1. 发明申请

US20120132593A1 SYSTEMS AND METHODS FOR MAGNETIC SEPARATION OF BIOLOGICAL MATERIALS 审中-公开
标题翻译：用于生物材料磁分离的系统和方法
公开(公告)号：US20120132593A1
公开(公告)日：2012-05-31
申请号：US12957240
申请日：2010-11-30
申请人： Sunil Srinivasa Murthy , James William Bray , Shankar Chandrasekaran , Arvind Kumar Tiwari , Aaron Joseph Dulgar-Tulloch , Munish Vishwas Inamdar
发明人： Sunil Srinivasa Murthy , James William Bray , Shankar Chandrasekaran , Arvind Kumar Tiwari , Aaron Joseph Dulgar-Tulloch , Munish Vishwas Inamdar
IPC分类号： B03C1/02 , B07C5/34 , C12M1/42
CPC分类号： C12M47/10 , B03C1/0332 , B03C1/288 , B03C2201/26 , B07C5/344 , C12M47/02
摘要： A magnetic separator comprising a separation chamber is provided. The separation chamber comprises a having an inlet and at least one outlet opposite the inlet in a downstream direction, and a magnetic source operatively coupled to the separation chamber. The magnetic source comprises a plurality of magnets that can be selectively turned off and on to create a dynamic magnetic field in the separation chamber.
摘要翻译：提供了一种包括分离室的磁选机。分离室包括具有入口和在下游方向上与入口相对的至少一个出口以及可操作地耦合到分离室的磁源。磁源包括可以选择性地关闭和接通以在分离室中产生动态磁场的多个磁体。

2. 发明申请

US20120135494A1 SYSTEMS AND METHODS FOR MAGNETIC SEPARATION OF BIOLOGICAL MATERIALS 审中-公开
标题翻译：用于生物材料磁分离的系统和方法
公开(公告)号：US20120135494A1
公开(公告)日：2012-05-31
申请号：US12957254
申请日：2010-11-30
申请人： Sunil Srinivasa Murthy , James William Bray , Shankar Chandrasekaran , Arvind Kumar Tiwari , Aaron Joseph Dulgar-Tulloch , Munish Vishwas Inamdar
发明人： Sunil Srinivasa Murthy , James William Bray , Shankar Chandrasekaran , Arvind Kumar Tiwari , Aaron Joseph Dulgar-Tulloch , Munish Vishwas Inamdar
IPC分类号： C12N13/00 , C07K1/14 , C07H21/00 , C12M1/00 , B01D11/02
CPC分类号： B07C5/344 , B03C1/0332 , B03C1/288 , B03C2201/26 , C07K1/14 , C12M47/02 , C12M47/10 , C12N1/02 , C12N13/00
摘要： A magnetic separator comprising a separation chamber is provided. The magnetic separator comprises an inlet and at least one outlet, and a magnetic source operatively coupled to the separation chamber and comprising a plurality of magnets that can be selectively turned off and on to create a dynamic magnetic field in the separation chamber.
摘要翻译：提供了一种包括分离室的磁选机。磁分离器包括入口和至少一个出口，以及可操作地耦合到分离室的磁源，并且包括可以选择性地关闭和打开以在分离室中产生动态磁场的多个磁体。

3. 发明申请

US20110024331A1 HIGH THROUGHPUT MAGNETIC ISOLATION TECHNIQUE AND DEVICE FOR BIOLOGICAL MATERIALS 有权
标题翻译：高强度磁分离技术和生物材料装置
公开(公告)号：US20110024331A1
公开(公告)日：2011-02-03
申请号：US12533180
申请日：2009-07-31
申请人： Sunil Srinivasa Murthy , Aaron Joseph Dulgar-Tulloch , James William Bray , Shankar Chandrasekaran , Arvind Kumar Tiwari
发明人： Sunil Srinivasa Murthy , Aaron Joseph Dulgar-Tulloch , James William Bray , Shankar Chandrasekaran , Arvind Kumar Tiwari
IPC分类号： B03C1/01
CPC分类号： B03C1/288 , B03C1/0332 , B03C1/0335 , B03C2201/18 , B03C2201/26
摘要： The present application discloses a process for the high throughput separation of at least one distinct biological material from a sample using magnetic tags and a magnetic separation set up capable of processing at least about 106 units/second. A magnetic field gradient is used to deflect target material bearing a magnet tag from one laminar flow stream to another so that the magnetically tagged target material exits a separation chamber via a different outlet than the rest of the sample. The process is applicable to isolating several distinct biological materials by directing each via magnetic deflection to its own unique outlet. The application also discloses a system for performing the process and a kit that includes the system and the magnetic tags.
摘要翻译：本申请公开了一种使用磁性标签和至少能够处理至少约106单位/秒的磁分离装置从至少一种不同的生物材料与样品分离高通量的方法。使用磁场梯度将具有磁性标签的目标材料从一个层流流转移到另一层，使得磁标记的靶材料通过与样品其余部分不同的出口离开分离室。该方法适用于通过将每个通过磁偏转指向其自己的独特出口来分离几种不同的生物材料。本申请还公开了一种用于执行该过程的系统和包括该系统和磁性标签的套件。

4. 发明授权

US08083069B2 High throughput magnetic isolation technique and device for biological materials 有权
标题翻译：高通量磁隔离技术和生物材料装置
公开(公告)号：US08083069B2
公开(公告)日：2011-12-27
申请号：US12533180
申请日：2009-07-31
申请人： Sunil Srinivasa Murthy , Aaron Joseph Dulgar-Tulloch , James William Bray , Shankar Chandrasekaran , Arvind Kumar Tiwari
发明人： Sunil Srinivasa Murthy , Aaron Joseph Dulgar-Tulloch , James William Bray , Shankar Chandrasekaran , Arvind Kumar Tiwari
IPC分类号： B03C1/00 , B07C5/02
CPC分类号： B03C1/288 , B03C1/0332 , B03C1/0335 , B03C2201/18 , B03C2201/26
摘要： The present application discloses a process for the high throughput separation of at least one distinct biological material from a sample using magnetic tags and a magnetic separation set up capable of processing at least about 106 units/second. A magnetic field gradient is used to deflect target material bearing a magnet tag from one laminar flow stream to another so that the magnetically tagged target material exits a separation chamber via a different outlet than the rest of the sample. The process is applicable to isolating several distinct biological materials by directing each via magnetic deflection to its own unique outlet. The application also discloses a system for performing the process and a kit that includes the system and the magnetic tags.
摘要翻译：本申请公开了一种使用磁性标签和至少能够处理至少约106单位/秒的磁分离装置从至少一种不同的生物材料与样品分离高通量的方法。使用磁场梯度将具有磁性标签的目标材料从一个层流流转移到另一层，使得磁标记的靶材料通过与样品其余部分不同的出口离开分离室。该方法适用于通过将每个通过磁偏转指向其自己的独特出口来分离几种不同的生物材料。本申请还公开了一种用于执行该过程的系统和包括该系统和磁性标签的套件。

5. 发明申请

US20120291570A1 SENSOR ASSEMBLIES AND METHODS OF ASSEMBLING SAME 失效
标题翻译：传感器组件及其组装方法
公开(公告)号：US20120291570A1
公开(公告)日：2012-11-22
申请号：US13112187
申请日：2011-05-20
申请人： Jacob John Kittleson , Shankar Chandrasekaran , Munish Vishwas Inamdar
发明人： Jacob John Kittleson , Shankar Chandrasekaran , Munish Vishwas Inamdar
IPC分类号： G01D7/02 , B23P17/04 , G01D21/00
CPC分类号： G01D11/30 , G01D11/245
摘要： A method for assembling a sensor assembly includes providing a sensing device configured to measure at least one variable. The method also includes at least partially enclosing a magnetic material within an enclosure. At least a portion of the enclosure is manufactured from a material having a permeability that facilitates forming a magnetic field therein. The method also includes coupling the sensing device to a first portion of the enclosure. The enclosure includes at least one second portion that is movable with respect to the first portion of the enclosure such that a magnetic coupling force is induced external to the enclosure to facilitate coupling the sensor assembly to a magnetic surface.
摘要翻译：一种用于组装传感器组件的方法包括提供被配置为测量至少一个变量的感测装置。该方法还包括在外壳内至少部分地包围磁性材料。外壳的至少一部分由具有促进其中形成磁场的渗透性的材料制成。该方法还包括将感测装置耦合到外壳的第一部分。所述外壳包括至少一个第二部分，所述至少一个第二部分可相对于所述外壳的所述第一部分移动，使得在所述外壳外部引入磁耦合力以便于将所述传感器组件耦合到磁性表面。

6. 发明授权

US08667856B2 Sensor assemblies and methods of assembling same 失效
标题翻译：传感器组件及组装方法
公开(公告)号：US08667856B2
公开(公告)日：2014-03-11
申请号：US13112187
申请日：2011-05-20
申请人： Jacob John Kittleson , Shankar Chandrasekaran , Munish Vishwas Inamdar
发明人： Jacob John Kittleson , Shankar Chandrasekaran , Munish Vishwas Inamdar
IPC分类号： G01D21/00 , G01D7/02 , B25B11/00
CPC分类号： G01D11/30 , G01D11/245
摘要： A method for assembling a sensor assembly includes providing a sensing device configured to measure at least one variable. The method also includes at least partially enclosing a magnetic material within an enclosure. At least a portion of the enclosure is manufactured from a material having a permeability that facilitates forming a magnetic field therein. The method also includes coupling the sensing device to a first portion of the enclosure. The enclosure includes at least one second portion that is movable with respect to the first portion of the enclosure such that a magnetic coupling force is induced external to the enclosure to facilitate coupling the sensor assembly to a magnetic surface.
摘要翻译：一种用于组装传感器组件的方法包括提供被配置为测量至少一个变量的感测装置。该方法还包括在外壳内至少部分地包围磁性材料。外壳的至少一部分由具有促进其中形成磁场的渗透性的材料制成。该方法还包括将感测装置耦合到外壳的第一部分。所述外壳包括至少一个第二部分，所述至少一个第二部分可相对于所述外壳的所述第一部分移动，使得在所述外壳外部引入磁耦合力以便于将所述传感器组件耦合到磁性表面。

7. 发明授权

US07338640B2 Thermopile-based gas sensor 失效
标题翻译：基于热电堆的气体传感器
公开(公告)号：US07338640B2
公开(公告)日：2008-03-04
申请号：US11095243
申请日：2005-03-31
申请人： Sunil Srinivasa Murthy , Anis Zribi , Shankar Chandrasekaran
发明人： Sunil Srinivasa Murthy , Anis Zribi , Shankar Chandrasekaran
IPC分类号： B32B5/02 , B32B27/04 , B32B27/12 , G01N7/00 , G01N21/00
CPC分类号： G01N25/4893 , Y10T436/11
摘要： A method of manufacturing a sensor is provided. The method includes disposing a sacrificial layer on a substrate, disposing a low-thermal-conductivity layer on the sacrificial layer, and disposing a first set of conductive arms and a second set of conductive arms on the low-thermal-conductivity layer to form a plurality of thermal junctions. The plurality of thermal junctions is adapted to form a plurality of hot junctions and a plurality of cold junctions when subjected to a difference in temperature. The method also includes removing the sacrificial layer and a portion of the low-thermal-conductivity layer to form a cavity therein. The cavity is configured to provide insulation for the plurality of hot junctions. A thermopile sensor is also provided, and a calorimetric gas sensor implementing the thermopile sensor is provided.
摘要翻译：提供一种制造传感器的方法。该方法包括在衬底上设置牺牲层，在牺牲层上设置低热导率层，以及将第一组导电臂和第二组导电臂设置在低热导率层上以形成多个热路口。多个热接头适于在经受温差时形成多个热接点和多个冷接点。该方法还包括去除牺牲层和低热导率层的一部分以在其中形成空腔。空腔构造成为多个热接点提供绝缘。还提供热电堆传感器，并提供实现热电堆传感器的量热气体传感器。

8. 发明申请

US20110166800A1 FLOW SENSOR ASSEMBLIES 失效
标题翻译：流量传感器总成
公开(公告)号：US20110166800A1
公开(公告)日：2011-07-07
申请号：US12683474
申请日：2010-01-07
申请人： Ertugrul Berkcan , Shankar Chandrasekaran , Bo Li , Stanton Earl Weaver, JR.
发明人： Ertugrul Berkcan , Shankar Chandrasekaran , Bo Li , Stanton Earl Weaver, JR.
IPC分类号： G01F1/00
CPC分类号： G01F1/66 , G01F1/712
摘要： A flow sensor assembly is provided and includes a flow conduit configured to impart a disturbance to a flow, multiple sensors disposed at respective sensing locations along the flow conduit. Each sensor is responsive to the disturbance of the flow and generates a corresponding response signal. The flow sensor assembly further includes a processor operably connected to each sensor, the processor being configured to compute a cross-correlation function between the response signals generated by said sensors, and determine a flow rate and a direction for the flow through the conduit based on the computed cross-correlation function. Additional flow sensor assembly arrangements are also disclosed.
摘要翻译：提供了一种流量传感器组件，并且包括配置成对流动造成干扰的流动管道，设置在沿着流动管道的各个感测位置处的多个传感器。每个传感器响应于流动的干扰并产生相应的响应信号。所述流量传感器组件还包括可操作地连接到每个传感器的处理器，所述处理器被配置为计算由所述传感器产生的所述响应信号之间的互相关函数，并且基于所述传感器确定流速和通过所述导管的流动的方向计算的互相关函数。还公开了附加的流量传感器组件装置。

9. 发明申请

US20110075142A1 OPTICAL DETECTION SYSTEM 审中-公开
标题翻译：光学检测系统
公开(公告)号：US20110075142A1
公开(公告)日：2011-03-31
申请号：US12566809
申请日：2009-09-25
申请人： Sandip Maity , Ayan Banerjee , Shankar Chandrasekaran , Anis Zribi , Shivappa Ningappa Goravar , David Cecil Hays , Dirk Lange , Renato Guida
发明人： Sandip Maity , Ayan Banerjee , Shankar Chandrasekaran , Anis Zribi , Shivappa Ningappa Goravar , David Cecil Hays , Dirk Lange , Renato Guida
IPC分类号： G01J3/28 , G01N21/25 , G02B6/10 , G02B27/00
CPC分类号： G01J3/26 , G01J3/02 , G01J3/0208 , G01J3/0218 , G01J3/0229 , G01J3/1895 , G01J3/44 , G02B6/29358
摘要： Optical detection systems and optical spectrometric systems are presented. One embodiment is a parallelized optical detection system. The detection system includes collector optics configured to receive an input optical signal, a plurality of optical filters and a plurality of tunable cavities. The collector optics includes at least one collector lens and at least one fiber multiplexer. The plurality of optical filters are configured to receive the input optical signal from the fiber multiplexer, and have serially varying pass band configured to filter the input optical signal at respective bandwidths. Each of the plurality of tunable cavities is optically coupled to each filter of the respective plurality of optical filters to receive a respective filtered output signal. The plurality of tunable cavities have band-pass frequencies with center frequencies staggered. At least one fiber demultiplexer is configured to receive respective filtered signals from the plurality of tunable cavities, and at least one detector is configured to receive and detect an output optical signal from the demultiplexer.
摘要翻译：介绍了光学检测系统和光谱系统。一个实施例是并行光学检测系统。检测系统包括被配置为接收输入光信号的收集器光学器件，多个光学滤波器和多个可调谐空腔。收集器光学器件包括至少一个收集透镜和至少一个光纤多路复用器。多个光学滤波器被配置为从光纤多路复用器接收输入光信号，并且具有被配置为在相应带宽处对输入光信号进行滤波的串联变化的通带。多个可调谐空腔中的每一个光学耦合到相应的多个滤光器的每个滤光器以接收相应的滤波输出信号。多个可调谐腔具有中心频率交错的带通频率。至少一个光纤解复用器被配置为从多个可调谐空腔接收相应的滤波信号，并且至少一个检测器被配置为接收和检测来自解复用器的输出光信号。

10. 发明申请

US20100220331A1 Micro-electromechanical system fabry-perot filter cavity 审中-公开
标题翻译：微机电系统fabry-perot过滤器腔
公开(公告)号：US20100220331A1
公开(公告)日：2010-09-02
申请号：US11447779
申请日：2006-06-06
申请人： Anis Zribi , Glenn S. Claydon , David C. Hays , Stacey Kennerly , Long Que , Shankar Chandrasekaran , Shivappa Goravar , Ayan Banerjee
发明人： Anis Zribi , Glenn S. Claydon , David C. Hays , Stacey Kennerly , Long Que , Shankar Chandrasekaran , Shivappa Goravar , Ayan Banerjee
IPC分类号： G01J3/45 , G02B26/00
CPC分类号： G01J3/26 , G01J3/06 , G02B26/001
摘要： According to some embodiments, a micro-electrical mechanical system apparatus includes an actuator within a plane and at least one movable mirror oriented substantially normal to the plane. The actuator may move the movable mirror with respect to a fixed mirror oriented substantially normal to the plane and substantially parallel to the movable mirror. The space between the fixed and movable mirrors might comprise, for example, a Fabry-Perot filter cavity for a spectrometer.
摘要翻译：根据一些实施例，微电机械系统装置包括在平面内的致动器和基本上垂直于该平面定向的至少一个可移动镜。致动器可以相对于基本上垂直于平面定向并且基本上平行于可移动镜的固定镜移动可移动镜。固定镜和可移动镜之间的空间可以包括例如用于光谱仪的法布里 - 珀罗滤光腔。

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