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    • 1. 发明授权
    • Method and apparatus for assessment of fluid responsiveness
    • 评估液体反应性的方法和装置
    • US08529458B2
    • 2013-09-10
    • US12891795
    • 2010-09-27
    • Sunghan KimPedro Mateo Riobo AboyJames McNames
    • Sunghan KimPedro Mateo Riobo AboyJames McNames
    • A61B5/02
    • A61B5/0205A61B5/412A61B5/4848A61B2505/03
    • Methods and apparatus for determining a cardiac parameter from cardiovascular pressure signals including arterial blood pressure (ABP) and the photoplethysmographic signal to quantify the degree of amplitude modulation due to respiration and predict fluid responsiveness are disclosed. Disclosed embodiments include a method for assessing fluid responsiveness implemented in a digital computer with one or more processors comprising: (a) measuring a cardiovascular signal, and (b) computing a dynamic index predictive of fluid responsiveness from said cardiovascular signal using a nonlinear state space estimator. According to one particular embodiment, and without limitation, the nonlinear state space estimator is based on a model for cardiovascular signals such as arterial blood pressure or plethysmogram signals, and employs a marginalized particle filter to estimate a dynamic index predictive of fluid responsiveness that is substantially equivalent to a variation in pulse pressure of said cardiovascular signal.
    • 公开了用于从心血管压力信号(包括动脉血压(ABP))和光电体积描记信号确定心脏参数的方法和装置,以量化由呼吸引起的幅度调制程度并预测流体反应性。 公开的实施例包括用于评估在具有一个或多个处理器的数字计算机中实现的流体响应性的方法,包括:(a)测量心血管信号,以及(b)使用非线性状态空间计算预测来自所述心血管信号的流体响应性的动态指数 估计。 根据一个特定实施例,非限制性地,非线性状态空间估计器基于诸如动脉血压或体积描记信号的心血管信号的模型,并且使用边缘化的粒子滤波器来估计预测流体响应性的动态指数,其基本上 相当于所述心血管信号的脉压的变化。
    • 2. 发明申请
    • Method and Apparatus for Assessment of Fluid Responsiveness
    • 流体响应性评估方法与装置
    • US20110077532A1
    • 2011-03-31
    • US12891795
    • 2010-09-27
    • Sunghan KimMateo AboyJames McNames
    • Sunghan KimMateo AboyJames McNames
    • A61B5/021A61B5/02
    • A61B5/0205A61B5/412A61B5/4848A61B2505/03
    • Methods and apparatus for determining a cardiac parameter from cardiovascular pressure signals including arterial blood pressure (ABP) and the photoplethysmographic signal to quantify the degree of amplitude modulation due to respiration and predict fluid responsiveness are disclosed. Disclosed embodiments include a method for assessing fluid responsiveness implemented in a digital computer with one or more processors comprising: (a) measuring a cardiovascular signal, and (b) computing a dynamic index predictive of fluid responsiveness from said cardiovascular signal using a nonlinear state space estimator. According to one particular embodiment, and without limitation, the nonlinear state space estimator is based on a model for cardiovascular signals such as arterial blood pressure or plethysmogram signals, and employs a marginalized particle filter to estimate a dynamic index predictive of fluid responsiveness that is substantially equivalent to a variation in pulse pressure of said cardiovascular signal.
    • 公开了用于从心血管压力信号(包括动脉血压(ABP))和光电体积描记信号确定心脏参数的方法和装置,以量化由呼吸引起的幅度调制程度并预测流体反应性。 公开的实施例包括用于评估在具有一个或多个处理器的数字计算机中实现的流体响应性的方法,包括:(a)测量心血管信号,以及(b)使用非线性状态空间计算预测来自所述心血管信号的流体响应性的动态指数 估计。 根据一个特定实施例,非限制性地,非线性状态空间估计器基于诸如动脉血压或体积描记信号的心血管信号的模型,并且使用边缘化的粒子滤波器来估计预测流体响应性的动态指数,其基本上 相当于所述心血管信号的脉压的变化。
    • 6. 发明授权
    • Monomers, conjugated polymers and electronic devices using such polymers
    • 单体,共轭聚合物和使用这种聚合物的电子器件
    • US07138483B2
    • 2006-11-21
    • US10771014
    • 2004-02-03
    • Hailiang WangFrank P. UckertSunghan Kim
    • Hailiang WangFrank P. UckertSunghan Kim
    • C08G69/00C08G75/00C08G73/00C07D291/00C07D277/00
    • C08G73/22C08G61/10C08G61/123
    • The energy levels (HOMO, LUMO) of the conjugated polymer are tuned independently, so that an energy match on both sides of the device can be accomplished while keeping the emission color in the blue region. Such polymers can be formed by polymerization of a mixture of monomers. The mixture of the monomers contains at least one monomer having an electron-deficient group sandwiched by two aromatic hydrocarbon groups (“Monomer (I)”) and at least one hole transporting (“HT”) monomer. The mixture of monomers may also contain a solubility enhancement (“SE”) monomer and/or a Branching Monomer. Such polymers can be used in fabricating light emitting diodes to achieve some of the best device performance to date including high efficiency and blue color purity.
    • 共轭聚合物的能级(HOMO,LUMO)被独立地调谐,使得能够在将发射颜色保持在蓝色区域中的同时实现装置两侧的能量匹配。 这样的聚合物可以通过单体混合物的聚合形成。 单体的混合物含有至少一个具有被两个芳族烃基(“单体(I)”)和至少一个空穴传输(“HT”)单体夹在中的电子缺陷基团的单体。 单体的混合物还可以含有溶解度增强(“SE”)单体和/或支化单体。 这样的聚合物可以用于制造发光二极管,以实现迄今为止的一些最佳的器件性能,包括高效率和蓝色纯度。