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1. 发明授权

US08815578B2 Cell culture tube and multiple roller tube cell culture apparatus including the same 有权
标题翻译：细胞培养管和包括其的多辊管细胞培养装置
公开(公告)号：US08815578B2
公开(公告)日：2014-08-26
申请号：US12596693
申请日：2008-04-10
申请人： Sung Ho Shin , Jung Gyu Woo , Jai Myung Yang , Jai Jun Choung , Kyung Suk Kim , Mi Ran Choi
发明人： Sung Ho Shin , Jung Gyu Woo , Jai Myung Yang , Jai Jun Choung , Kyung Suk Kim , Mi Ran Choi
IPC分类号： C12M3/04 , C12M1/24
CPC分类号： C12M27/12 , C12M41/44
摘要： Disclosed is a cell culture tube, having in opposite end walls two respective eccentric openings which communicate with each other through an inner straight passage formed in the cell culture tube, in which the inner straight passage is tilted at an angle relative to a longitudinal axis of the cell culture tube to allow a culture medium to smoothly flow into and out of the inner passage through the openings. Also, provided is a multiple cell culture system using a plurality of the culture tubes.
摘要翻译：公开了一种细胞培养管，其在相对端壁处具有两个相应的偏心开口，所述偏心开口通过形成在细胞培养管中的内直通道彼此连通，其中内直通道相对于纵向轴线成一定角度倾斜细胞培养管，以允许培养基顺利地流入和流出通过开口的内部通道。此外，提供了使用多个培养管的多细胞培养系统。

2. 发明申请

US20100136672A1 Cell Culture Tube and Multiple Roller Tube Cell Culture Apparatus Including the Same 有权
标题翻译：细胞培养管和多辊管细胞培养装置包括它
公开(公告)号：US20100136672A1
公开(公告)日：2010-06-03
申请号：US12596693
申请日：2008-04-10
申请人： Sung Ho Shin , Jung Gyu Woo , Jai Myung Yang , Jai Jun Choung , Kyung Suk Kim , Mi Ran Choi
发明人： Sung Ho Shin , Jung Gyu Woo , Jai Myung Yang , Jai Jun Choung , Kyung Suk Kim , Mi Ran Choi
IPC分类号： C12M1/24
CPC分类号： C12M27/12 , C12M41/44
摘要： Disclosed is a cell culture tube, having in opposite end walls two respective eccentric openings which communicate with each other through an inner straight passage formed in the cell culture tube, in which the inner straight passage is tilted at an angle relative to a longitudinal axis of the cell culture tube to allow a culture medium to smoothly flow into and out of the inner passage through the openings. Also, provided is a multiple cell culture system using a plurality of the culture tubes.
摘要翻译：公开了一种细胞培养管，其在相对端壁处具有两个相应的偏心开口，所述偏心开口通过形成在细胞培养管中的内直通道彼此连通，其中内直通道相对于纵向轴线成一定角度倾斜细胞培养管，以允许培养基顺利地流入和流出穿过开口的内部通道。此外，提供了使用多个培养管的多细胞培养系统。

3. 发明申请

US20120121545A1 Pharmaceutical Composition For Bone Disease Treatment Or Countering Inflammation, Comprising Cartilage Stem Cells As An Active Principle 审中-公开
标题翻译：用于骨病治疗或抗炎的药物组合物，包括软骨干细胞作为主动原理
公开(公告)号：US20120121545A1
公开(公告)日：2012-05-17
申请号：US13144506
申请日：2010-01-15
申请人： Kyung Suk Kim , Jai Jun Choung , Hyun Soo Yoon , Jun Ho Lee , sae Kwang Ku
发明人： Kyung Suk Kim , Jai Jun Choung , Hyun Soo Yoon , Jun Ho Lee , sae Kwang Ku
IPC分类号： A61K35/32 , A61P19/08 , A61P29/00
CPC分类号： A61K35/32 , A61K35/12 , C12N5/0655 , C12N5/0662
摘要： Disclosed is a pharmaceutical composition for treating bone disease or countering inflammation containing cartilage stem cells as an active ingredient. The present disclosure provides a novel cell treatment regimen for bone disease and inflammatory disease using the cartilage stem cells as an active ingredient. When the cartilage stem cells of the present disclosure are administered into the articular capsule, the administered cartilage stem cells are highly effective in treating bone disease and inflammatory bone disease since they grow or differentiate into chondrocytes and exhibit an anti-inflammatory activity. Since the cartilage stem cells of the present disclosure do not express histocompatibility antigens which give rise to rejection in tissue or organ transplants, autologous cells or exogenous cells can be used during cell transplantation for treatment of bone disease and inflammation.
摘要翻译：公开了一种用于治疗骨病或抗炎的药物组合物，其含有软骨干细胞作为活性成分。本公开提供了使用软骨干细胞作为活性成分的用于骨疾病和炎性疾病的新型细胞治疗方案。当将本公开的软骨干细胞施用于关节囊时，所施用的软骨干细胞由于它们生长或分化成软骨细胞并表现出抗炎活性，因此在治疗骨病和炎症性骨病方面是非常有效的。由于本公开的软骨干细胞不表达在组织或器官移植中引起排斥反应的组织相容性抗原，因此在细胞移植期间可以使用自体细胞或外源细胞用于治疗骨疾病和炎症。

4. 发明申请

US20100304472A1 Cell Culture Apparatus and Mass Automatic Cell Culture Device Having It 有权
标题翻译：细胞培养装置及其自动细胞培养装置
公开(公告)号：US20100304472A1
公开(公告)日：2010-12-02
申请号：US12745029
申请日：2008-11-28
申请人： Kyung Suk Kim , Jai Jun Choung
发明人： Kyung Suk Kim , Jai Jun Choung
IPC分类号： C12M1/24
CPC分类号： G01N35/1095 , C12M23/08 , C12M23/22 , C12M23/38 , C12M23/44 , C12M23/48 , C12M23/58 , C12M27/10 , C12M29/00 , C12M41/48
摘要： The present invention relates to a cell culture apparatus and a mass automatic cell culture device having it. There is provided a cell culture apparatus comprising a cylindrical cell culture flask which is air-tightly sealed to culture a cell using a culture solution and various gases and formed of a transparent material to observe an internal portion thereof, an injection unit for supplying the cell and the culture solution into the cell culture flask, a collection unit for discharging the cells and the culture solution from the cell culture flask, and a cell culture flask receiving part which is comprised of first and second vertical frames in which a plurality of injecting parts and collecting parts for respectively receiving the injection unit and the collection unit are vertically formed to be opposed to each other, and plate type connection parts which are respectively disposed between upper ends and lower ends of the two opposed vertical frames to be spaced apart from each other in regular intervals, thereby connecting the first and second vertical frames, and a mass automatic cell culture device having it.
摘要翻译：细胞培养装置及具有该细胞培养装置的大容量自动细胞培养装置技术领域本发明涉及具有该细胞培养装置的大容量自动细胞培养装置。提供一种细胞培养装置，其包括圆筒形细胞培养瓶，气瓶密封以培养细胞，使用培养液和各种气体，并由透明材料形成，以观察其内部部分，用于供应细胞的注射单元将培养液投入到细胞培养烧瓶中，从细胞培养烧瓶中排出细胞和培养液的收集单元和由第一和第二纵向框架构成的细胞培养烧瓶容纳部，其中多个注射部并且用于分别接收注射单元和收集单元的收集部分被竖直地形成为彼此相对，并且分别设置在两个相对的竖直框架的上端和下端之间的板型连接部分与每个其他规则的间隔，从而连接第一和第二垂直框架和大规模自动细胞培养具有它的设备。

5. 发明授权

US08481305B2 Rotation driving device for cell culturing 有权
标题翻译：用于细胞培养的旋转驱动装置
公开(公告)号：US08481305B2
公开(公告)日：2013-07-09
申请号：US12744718
申请日：2008-11-28
申请人： Kyung Suk Kim , Jai Jun Choung
发明人： Kyung Suk Kim , Jai Jun Choung
IPC分类号： C12M1/22 , C12M3/00
CPC分类号： C12M27/10
摘要： The present invention relates to a rotation driving device for cell culturing, comprising: a power supplying unit operated by receiving an electric power from an outside; a rotational part rotated by the power supplying unit; and a driving part which is provided at an upper side of the rotational part and maintained in a stopped state during the rotation of the rotational part, and of which an inclination is changed according to a rotational direction of the rotational part. According to the present invention, there is provided a rotation driving device a rotation driving device which enables cells to be uniformly grown by equally distributing a culture solution with help of inclination control, of which a rotational speed is also controlled and which has a firm structure with a strong durability.
摘要翻译：本发明涉及一种用于细胞培养的旋转驱动装置，包括：通过从外部接收电力而操作的供电单元; 由所述供电单元旋转的旋转部; 以及驱动部，其设置在所述旋转部的上侧，并且在所述旋转部的旋转期间保持在停止状态，并且所述驱动部的倾斜度根据所述旋转部的旋转方向而变化。根据本发明，提供了一种旋转驱动装置，其具有旋转驱动装置，该旋转驱动装置使得能够通过倾斜控制的均匀分布培养液均匀地生长细胞，其旋转速度也被控制并且具有坚固的结构具有很强的耐久性。

6. 发明授权

US09057715B2 Cell culture apparatus and mass automatic cell culture device having it 有权
标题翻译：具有细胞培养装置和大容量自动细胞培养装置
公开(公告)号：US09057715B2
公开(公告)日：2015-06-16
申请号：US12745029
申请日：2008-11-28
申请人： Kyung Suk Kim , Jai Jun Choung
发明人： Kyung Suk Kim , Jai Jun Choung
IPC分类号： C12M1/24 , C12M3/00 , G01N35/10 , C12M1/00 , C12M3/04 , C12M1/36
CPC分类号： G01N35/1095 , C12M23/08 , C12M23/22 , C12M23/38 , C12M23/44 , C12M23/48 , C12M23/58 , C12M27/10 , C12M29/00 , C12M41/48
摘要： The present invention relates to a cell culture apparatus and a mass automatic cell culture device having it. There is provided a cell culture apparatus comprising a cylindrical cell culture flask which is air-tightly sealed and formed of a transparent material to observe an internal portion thereof, an injection unit for supplying the cell and the culture solution into the cell culture flask, a collection unit for discharging the cells and the culture solution from the cell culture flask, and a cell culture flask receiving part which is comprised of first and second vertical frames in which a plurality of injecting parts and collecting parts, and plate type connection parts which are respectively disposed between upper ends and lower ends of the two opposed vertical frames to be spaced apart from each other in regular intervals, and a mass automatic cell culture device having it.
摘要翻译：细胞培养装置及具有该细胞培养装置的大容量自动细胞培养装置技术领域本发明涉及具有该细胞培养装置的大容量自动细胞培养装置。提供一种细胞培养装置，其包括气密密封并由透明材料形成以观察其内部的圆柱形细胞培养瓶，用于将细胞和培养溶液供应到细胞培养瓶中的注射单元，用于从细胞培养瓶中排出细胞和培养液的收集单元和由多个注射部分和收集部分组成的第一和第二垂直框架的细胞培养烧瓶接受部分和板状连接部分分别设置在两个相对的垂直框架的上端和下端之间以规则的间隔彼此间隔开，以及具有该自动细胞培养装置的大容量自动细胞培养装置。

7. 发明申请

US20100304474A1 Rotation Driving Device for Cell Culturing 有权
标题翻译：细胞培养用旋转驱动装置
公开(公告)号：US20100304474A1
公开(公告)日：2010-12-02
申请号：US12744718
申请日：2008-11-28
申请人： Kyung Suk Kim , Jai Jun Choung
发明人： Kyung Suk Kim , Jai Jun Choung
IPC分类号： C12M1/10
CPC分类号： C12M27/10
摘要： The present invention relates to a rotation driving device for cell culturing, comprising: a power supplying unit operated by receiving an electric power from an outside; a rotational part rotated by the power supplying unit; and a driving part which is provided at an upper side of the rotational part and maintained in a stopped state during the rotation of the rotational part, and of which an inclination is changed according to a rotational direction of the rotational part. According to the present invention, there is provided a rotation driving device a rotation driving device which enables cells to be uniformly grown by equally distributing a culture solution with help of inclination control, of which a rotational speed is also controlled and which has a firm structure with a strong durability.
摘要翻译：本发明涉及一种用于细胞培养的旋转驱动装置，包括：通过从外部接收电力而操作的供电单元; 由所述供电单元旋转的旋转部; 以及驱动部，其设置在所述旋转部的上侧，并且在所述旋转部的旋转期间保持在停止状态，并且所述驱动部的倾斜度根据所述旋转部的旋转方向而变化。根据本发明，提供了一种旋转驱动装置，其具有旋转驱动装置，该旋转驱动装置使得能够通过倾斜控制的均匀分布培养液均匀地生长细胞，其旋转速度也被控制并且具有坚固的结构具有很强的耐久性。

8. 发明申请

US20100304473A1 Cell Culture Flask and the Cell Culture Device Having it 审中-公开
标题翻译：细胞培养瓶和细胞培养装置
公开(公告)号：US20100304473A1
公开(公告)日：2010-12-02
申请号：US12745127
申请日：2008-11-28
申请人： Kyung Suk Kim , Jai Jun Choung
发明人： Kyung Suk Kim , Jai Jun Choung
IPC分类号： C12M1/00
CPC分类号： C12M23/08 , C12M23/22 , C12M23/38 , C12M23/44 , C12M29/00 , C12M29/26
摘要： The present invention relates to a cell culture flask for culturing a cell using a culture solution, particularly to a cell culture flask enabling to culture a cell without any contamination, to automatically introduce and discharge the culture solution or gases and to be stacked in turn, and a cell culture device having the same. The present invention provides a cell culture flask comprising a culture space with a predetermined area for culturing the cell; one or more culture solution inlet ports for introducing the culture solution or the cell into the culture space; one or more culture solution outlet ports for discharging the culture solution or the cell supplied to the culture space; and one or more gas inlet ports for introducing the various gases into the culture space, wherein the cell culture flask is made airtight and formed of a transparent material so that a user can see an internal portion of the cell culture flask, and a cell culture device having the same.
摘要翻译：本发明涉及使用培养液培养细胞的细胞培养瓶，特别涉及能够培养细胞而没有任何污染的细胞培养烧瓶，以自动引入和排出培养液或气体，并依次层叠，和具有该细胞培养装置的细胞培养装置。本发明提供一种细胞培养瓶，其包含具有用于培养细胞的预定区域的培养空间; 用于将培养液或细胞引入培养空间的一个或多个培养溶液入口; 一个或多个培养液出口，用于排出供应到培养空间的培养液或细胞; 以及用于将各种气体引入培养空间的一个或多个气体入口，其中细胞培养瓶被气密地制成并由透明材料形成，使得使用者可以看到细胞培养瓶的内部部分和细胞培养物具有相同的装置

9. 发明授权

US09446061B2 Composition containing antibiotics and lysophosphatidylcholine for boosting immunity or treatment of bacterial infections 有权
标题翻译：含有抗生素和溶血磷脂酰胆碱的组合物，用于增强免疫力或治疗细菌感染
公开(公告)号：US09446061B2
公开(公告)日：2016-09-20
申请号：US14128688
申请日：2012-06-22
申请人： Jai Jun Choung , Sae Kwang Ku , Dong Keun Song
发明人： Jai Jun Choung , Sae Kwang Ku , Dong Keun Song
IPC分类号： A61K45/06 , A61K31/661 , A61K31/685
CPC分类号： A61K31/685 , A61K31/661 , A61K45/06 , A61K2300/00
摘要： The present invention relates to: a pharmaceutical composition containing lysophosphatidylcholine or analogs thereof and antibiotics as active ingredients for boosting immunity or the treatment of bacterial infections; a method for boosting immunity or the treatment of bacterial infections, which comprises a step for administering the composition; and a kit containing the composition for boosting immunity or the treatment of bacterial infections.
摘要翻译：本发明涉及：含有溶血磷脂酰胆碱或其类似物的药物组合物和作为增强免疫力或治疗细菌感染的活性成分的抗生素; 一种用于增强免疫力或治疗细菌感染的方法，其包括施用该组合物的步骤; 以及包含用于增强免疫力或治疗细菌感染的组合物的试剂盒。

10. 发明申请

US20150125554A1 METHOD FOR PREPARING GRANULES OR PILLS CONTAINING EXTRACTS IN HIGH CONCENTRATION 审中-公开
标题翻译：用于在高浓度下制备含有提取物的颗粒或桩的方法
公开(公告)号：US20150125554A1
公开(公告)日：2015-05-07
申请号：US14410054
申请日：2012-07-11
申请人： Chil Surk Yoon , Jai Jun Choung , Soo Hyun Sung
发明人： Chil Surk Yoon , Jai Jun Choung , Soo Hyun Sung
IPC分类号： A61K36/254 , A61K9/20 , A61K45/06 , A61K36/232 , A61K36/88 , A61K36/72 , A61K9/14 , A61K36/481
CPC分类号： A61K36/254 , A61K9/14 , A61K9/1688 , A61K9/20 , A61K9/2866 , A61K9/5047 , A61K9/5063 , A61K36/00 , A61K36/232 , A61K36/481 , A61K36/72 , A61K36/88 , A61K45/06
摘要： The present invention relates to a method for preparing a granule or a pill containing a plant, medicinal herb or traditional oriental medicine decoction extract, comprising the steps of: (a) injecting a powdered plant, medicinal herb or traditional oriental medicine decoction extract into a fluidized-bed device and spraying purified water or a solution of the same type of extract as the extract powder at the extract powder while fluidizing the same, thereby generating microgranules of the extract powder; and (b) injecting the microgranules generated at step (a) as seeds into the fluidized-bed device and spraying a solution of the extract while fluidizing the same, thereby growing the microgranules to a predetermined size of granule or pill. According to the present invention, it is possible to prepare a granule or a pill containing an extract in a high concentration.
摘要翻译：本发明涉及一种制备含有植物，药草或传统东方汤剂提取物的颗粒或丸剂的方法，包括以下步骤：（a）将粉状植物，药草或传统东方汤剂提取物注入流化床装置，并在提取粉末中将纯化水或提取物提取物的相同类型的提取物的溶液喷雾，同时使其流出，从而产生提取物粉末的微粒; 和（b）将步骤（a）产生的微粒作为种子注入到流化床装置中，并在使其流化的同时喷洒提取物的溶液，从而使微粒生长至预定尺寸的颗粒或丸剂。根据本发明，可以制备含有高浓度提取物的颗粒或丸剂。

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