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    • 1. 发明授权
    • Heater for chemical vapor deposition equipment
    • 化学气相沉积设备加热器
    • US5648006A
    • 1997-07-15
    • US385968
    • 1995-02-09
    • Suk-Ki MinMoo Sung KimSeong-Il KimYong Kim
    • Suk-Ki MinMoo Sung KimSeong-Il KimYong Kim
    • H05B3/20C23C16/46H05B3/16H05B3/68
    • C23C16/46H05B3/16
    • A heater for a chemical vapor deposition equipment includes a meandering heating wire made of either molybdenum or tungsten and having a diameter of about 1 mm. The heating wire is laid on a heater disc that is made of either molybdenum, tungsten or ceramic. The heater disc is holed at its center for receiving a susceptor rotating shaft. A plurality of heating wire fixtures support the heating wire on the heater disc while spacing the heating wire from the heater disc at an interval, thus to prevent the heating wire from directly contacting the heater disc. Each of the heating wire fixtures is provided with a pair of lateral through holes, that is, a heating wire hole formed in an upper section of each fixture and a fixing wire hole formed in a lower section of each fixture. The heater also includes heat resisting plates that are made of either molybdenum or tungsten and placed on the bottom surface and the side surface of the heater disc for preventing side and downward radiation of the heat of the heating wire. The heater heats a substrate to a high temperature not less than 1500.degree. C. and achieves an excellent heating efficiency.
    • 用于化学气相沉积设备的加热器包括由钼或钨制成并具有约1mm直径的曲折加热丝。 加热丝放置在由钼,钨或陶瓷制成的加热盘上。 加热盘在其中心处是用于接收基座旋转轴的。 多个加热线夹具支撑加热盘上的加热线,同时间隔加热丝与加热盘间隔开,从而防止加热线直接接触加热盘。 每个加热线夹具设置有一对横向通孔,即,形成在每个固定装置的上部中的加热丝孔和形成在每个夹具的下部中的固定线孔。 加热器还包括由钼或钨制成并且放置在加热盘的底表面和侧表面上的耐热板,用于防止加热丝的热量的侧向和向下辐射。 加热器将基板加热至不低于1500℃的高温,并实现优良的加热效率。
    • 5. 发明授权
    • Process for preparation of imipenem
    • 亚胺培南的制备方法
    • US07507814B2
    • 2009-03-24
    • US10563250
    • 2004-12-09
    • Hyun Seop BaeTae Seop HwangChan Yong AhnChang Hoon OhMoo Sung Kim
    • Hyun Seop BaeTae Seop HwangChan Yong AhnChang Hoon OhMoo Sung Kim
    • C07D477/20C07D477/18
    • C07D477/06C07D477/20C07D487/04
    • The invention provides a novel compound of Formula II which is useful in the preparation of imipenem monohydrate of Formula I, wherein R1 is a p-nitrobenzyl or p-methoxybenzyl group; and R2 and R3 may be identical to or different from each other and are each independently a C1-6alkyl or aryl group, or a derivative thereof, and a process for preparing the compound of Formula II by coupling (5R,6S) p-nitrobenzyl-3-(diphenylphosphono)-6-[(1R)-1-hydroxyethyl]-1-azabicyclo[3.2.0]hept-2-ene-7-one-2-carboxylate with 2-aminoetahnethiol hydrocloride in the presence of a base, followed by a reaction with a ketone. Further, the invention provides a process for preparing the compound of Formula I by reacting a compound of Formula II with isopropylformimidate or benzylformimidate in the presence of a base, followed by hydrogenation, separation and crystallization.
    • 本发明提供了一种新的式II化合物,其可用于制备式I的亚胺培南一水合物,其中R 1为对硝基苄基或对甲氧基苄基; 并且R 2和R 3可以彼此相同或不同,并且各自独立地为C 1-6烷基或芳基或其衍生物,以及通过将(5R,6S)对硝基苄基 -3-(二苯基膦酰基)-6 - [(1R)-1-羟乙基] -1-氮杂双环[3.2.0]庚-2-烯-7-酮-2-羧酸叔丁酯与2-氨基乙脑二醇氢氯化物 碱,然后与酮反应。 此外,本发明提供了通过在碱的存在下使式II化合物与异丙基甲酰亚胺酯或苄基甲酰亚氨酸酯反应,然后氢化,分离和结晶来制备式I化合物的方法。