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1. 发明授权

US08781254B2 Method, an apparatus and a computer program for data processing 有权
标题翻译：用于数据处理的方法，装置和计算机程序
公开(公告)号：US08781254B2
公开(公告)日：2014-07-15
申请号：US12516357
申请日：2007-11-26
申请人： Stewart Young , Daniel Bystrov , Thomas Netsch , Michael Kaus , Vladimir Pekar
发明人： Stewart Young , Daniel Bystrov , Thomas Netsch , Michael Kaus , Vladimir Pekar
IPC分类号： G06K9/36
CPC分类号： G06T7/149 , G06T7/12 , G06T7/70 , G06T2207/30016
摘要： A method of data processing is provided for estimating a position of an object in an image from a position of a reference object in a reference image. The method includes learning the position of the reference object in the reference image and its relation to a set of reference landmarks in the reference image, accessing the image, accessing the relation between the position of the reference object and the set of the reference landmarks, identifying a set of landmarks in the image corresponding to the set of the reference landmarks, and applying the relation to the set of landmarks in the image for estimating the position of the object in the image.
摘要翻译：提供一种数据处理方法，用于从参考图像中的参考对象的位置估计图像中的对象的位置。该方法包括：在参考图像中学习参考对象的位置及其与参考图像中的一组参考地标的关系，访问图像，访问参考对象的位置与参考地标集合之间的关系，识别对应于所述参考地标集合的图像中的一组地标，以及将所述关系应用于所述图像中的所述地标集合，以估计所述图像中的对象的位置。

2. 发明申请

US20100061632A1 METHOD, AN APPARATUS AND A COMPUTER PROGRAM FOR DATA PROCESSING 有权
标题翻译：方法，数据处理的装置和计算机程序
公开(公告)号：US20100061632A1
公开(公告)日：2010-03-11
申请号：US12516357
申请日：2007-11-26
申请人： Stewart Young , Daniel Bystrov , Thomas Netsch , Michael Kaus , Vladimir Pekar
发明人： Stewart Young , Daniel Bystrov , Thomas Netsch , Michael Kaus , Vladimir Pekar
IPC分类号： G06K9/34 , G06K9/46
CPC分类号： G06T7/149 , G06T7/12 , G06T7/70 , G06T2207/30016
摘要： The invention relates to a method for data processing. At stage 3 the position of the reference object in the reference image and its relation to a set of reference landmarks in the reference image is established at step 6. In order to enable this, the reference imaging of learning examples may be performed at step 2 and each reference image may be analyzed at step 4, the results may be stored in a suitably arranged database. In order to process the image under consideration, the image is accessed at step 11, the suitable landmark corresponding to the reference landmark in the reference image is identified at step 13 and the spatial relationship established at step 6 is applied to the landmark thereby providing the initial position of the object in the actual image. In case when for the object an imaging volume is selected, the method 1 according to the invention follows to step 7, whereby the scanning 17 is performed within the boundaries given by the thus established scanning volume. In case when for the object a model representative of the target is selected, the method 1 follows to the image segmentation step 19, whereby a suitable segmentation is performed. In case when for the model a deformable model is selected, the segmentation is performed by deforming the model thereby providing spatial boundaries of the target area. The invention further relates to an apparatus and a computer program for image processing.
摘要翻译：本发明涉及一种数据处理方法。在阶段3，在步骤6中建立参考图像中的参考对象的位置及其与参考图像中的一组参考标记的关系。为了实现这一点，可以在步骤2执行学习示例的参考成像并且可以在步骤4分析每个参考图像，结果可以存储在适当布置的数据库中。为了处理所考虑的图像，在步骤11访问图像，在步骤13识别与参考图像中的参考标记相对应的合适地标，并将在步骤6建立的空间关系应用于地标，从而提供物体在实际图像中的初始位置。在对于物体选择成像体积的情况下，根据本发明的方法1遵循步骤7，由此在由这样建立的扫描体积给出的边界内执行扫描17。在针对对象的情况下，选择了表示目标的模型，则对图像分割步骤19进行方法1，由此执行适当的分割。在为模型选择可变形模型的情况下，通过使模型变形从而提供目标区域的空间边界来执行分割。本发明还涉及一种用于图像处理的装置和计算机程序。

3. 发明授权

US08000508B2 User interface for motion analysis in kinematic MR studies 有权
标题翻译：用于运动学分析的用户界面
公开(公告)号：US08000508B2
公开(公告)日：2011-08-16
申请号：US11814406
申请日：2006-01-05
申请人： Daniel Bystrov , Vladimir Pekar , Kirsten Meetz , Thomas Netsch , Stewart Young
发明人： Daniel Bystrov , Vladimir Pekar , Kirsten Meetz , Thomas Netsch , Stewart Young
IPC分类号： G06K9/00
CPC分类号： G06T13/20 , G06T7/246 , G06T2207/10076 , G06T2207/10088 , G06T2207/30048
摘要： In a diagnostic imaging system (10), a user interface (82) facilitates viewing of 4D kinematic data sets. A set of reference points is selected in a first 3D image to designate an anatomical component. An algorithm (104) calculates a propagation of the selected reference points from the first 3D image into other 3D images. Transforms which describe the propagation of the reference points between 3D images are defined. An aligning algorithm (112) applies inverse of the transforms to the 3D images to define a series of frames for the video processor (120) to display, in which frames the designated anatomical component defined by the reference points in each of the 3D images remains fixed while the other portions of the anatomical region of interest move relative to the fixed designated anatomical component.
摘要翻译：在诊断成像系统（10）中，用户界面（82）便于观看4D运动数据集。在第一3D图像中选择一组参考点以指定解剖组件。算法（104）计算所选择的参考点从第一3D图像到其他3D图像的传播。定义描述3D图像之间参考点传播的变换。对准算法（112）将变换的逆向应用于3D图像以定义用于视频处理器（120）显示的一系列帧，其中由每个3D图像中的参考点定义的指定解剖组件保留固定，而感兴趣的解剖区域的其他部分相对于固定的指定解剖部件移动。

4. 发明申请

US20080069418A1 User Interface for Motion Analysis in Kinematic Mr Studies 有权
标题翻译：运动分析用户界面
公开(公告)号：US20080069418A1
公开(公告)日：2008-03-20
申请号：US11814406
申请日：2006-01-05
申请人： Daniel Bystrov , Vladimir Pekar , Kirsten Meetz , Thomas Netsch , Stewart Young
发明人： Daniel Bystrov , Vladimir Pekar , Kirsten Meetz , Thomas Netsch , Stewart Young
IPC分类号： G06K9/00
CPC分类号： G06T13/20 , G06T7/246 , G06T2207/10076 , G06T2207/10088 , G06T2207/30048
摘要： In a diagnostic imaging system (10), a user interface (82) facilitates viewing of 4D kinematic data sets. A set of reference points is selected in a first 3D image to designate an anatomical component. An algorithm (104) calculates a propagation of the selected reference points from the first 3D image into other 3D images. Transforms which describe the propagation of the reference points between 3D images are defined. An aligning algorithm (112) applies inverse of the transforms to the 3D images to define a series of frames for the video processor (120) to display, in which frames the designated anatomical component defined by the reference points in each of the 3D images remains fixed while the other portions of the anatomical region of interest move relative to the fixed designated anatomical component.
摘要翻译：在诊断成像系统（10）中，用户界面（82）便于观看4D运动数据集。在第一3D图像中选择一组参考点以指定解剖组件。算法（104）计算所选择的参考点从第一3D图像到其他3D图像的传播。定义描述3D图像之间参考点传播的变换。对准算法（112）将变换的逆向应用于3D图像以定义用于视频处理器（120）显示的一系列帧，其中由每个3D图像中的参考点定义的指定解剖组件保留固定，而感兴趣的解剖区域的其他部分相对于固定的指定解剖部件移动。

5. 发明申请

US20100295848A1 INTERACTIVE IMAGE SEGMENTATION 有权
标题翻译：互动图像分割
公开(公告)号：US20100295848A1
公开(公告)日：2010-11-25
申请号：US12863462
申请日：2009-01-07
申请人： Ruediger Grewer , Sebastian Dries , Daniel Bystrov , Vladimir Pekar , Torbjoern Vik , Heinrich Schulz , Michael Kaus
发明人： Ruediger Grewer , Sebastian Dries , Daniel Bystrov , Vladimir Pekar , Torbjoern Vik , Heinrich Schulz , Michael Kaus
IPC分类号： G06K9/34 , G06T17/00
CPC分类号： G06T7/11 , G06T2207/20101 , G06T2207/20128 , G06T2207/30004
摘要： When adapting models of anatomical structures in a patient for diagnosis or therapeutic planning, an atlas (26) of predesigned anatomical structure models or image volumes can be accessed, and a segmentation of one or more such structures can be selected and overlaid on an a 3D image of corresponding structure(s) in a clinical image (52) of a patient. A user can click on an initially unapproved segmentation 5 landmark (72) on the patient image (52), reposition the unapproved landmark, and approve the repositioned landmark. Remaining unapproved landmarks (72) are then repositioned as a function of the position of the approved landmark (92) using one or more interpolation techniques to adapt the model to the patient image on the fly.
摘要翻译：当适应用于诊断或治疗计划的患者中的解剖结构的模型时，可以访问预先设计的解剖结构模型或图像体积的图集（26），并且可以选择并覆盖在3D上的一个或多个这样的结构的分割在患者的临床图像（52）中的相应结构的图像。用户可以点击患者图像（52）上的最初未被批准的细分5地标（72），重新定位未经批准的地标，并批准重新定位的地标。然后通过使用一种或多种内插技术将剩余的未经批准的地标（72）重新定位为批准的地标（92）的位置的函数，以便将模型随时适应患者图像。

6. 发明授权

US08698795B2 Interactive image segmentation 有权
标题翻译：交互式图像分割
公开(公告)号：US08698795B2
公开(公告)日：2014-04-15
申请号：US12863462
申请日：2009-01-07
申请人： Ruediger Grewer , Sebastian Dries , Daniel Bystrov , Vladimir Pekar , Torbjoern Vik , Heinrich Schulz , Michael Kaus
发明人： Ruediger Grewer , Sebastian Dries , Daniel Bystrov , Vladimir Pekar , Torbjoern Vik , Heinrich Schulz , Michael Kaus
IPC分类号： G06T15/00 , G06K9/00
CPC分类号： G06T7/11 , G06T2207/20101 , G06T2207/20128 , G06T2207/30004
摘要： When adapting models of anatomical structures in a patient for diagnosis or therapeutic planning, an atlas (26) of predesigned anatomical structure models or image volumes can be accessed, and a segmentation of one or more such structures can be selected and overlaid on an a 3D image of corresponding structure(s) in a clinical image (52) of a patient. A user can click on an initially unapproved segmentation 5 landmark (72) on the patient image (52), reposition the unapproved landmark, and approve the repositioned landmark. Remaining unapproved landmarks (72) are then repositioned as a function of the position of the approved landmark (92) using one or more interpolation techniques to adapt the model to the patient image on the fly.
摘要翻译：当适应用于诊断或治疗计划的患者中的解剖结构的模型时，可以访问预先设计的解剖结构模型或图像体积的图集（26），并且可以选择并覆盖在3D上的一个或多个这样的结构的分割在患者的临床图像（52）中的相应结构的图像。用户可以点击患者图像（52）上的最初未被批准的分割5地标（72），重新定位未经批准的地标，并批准重新定位的地标。然后，使用一种或多种内插技术将剩余的未经批准的地标（72）重新定位为批准的地标（92）的位置的函数，以使模型在飞行中适应患者图像。

7. 发明授权

US08620056B2 Method, an apparatus, a system and a computer program for transferring scan geometry between subsequent scans 有权
标题翻译：用于在后续扫描之间传送扫描几何的方法，装置，系统和计算机程序
公开(公告)号：US08620056B2
公开(公告)日：2013-12-31
申请号：US12307620
申请日：2007-06-28
申请人： Daniel Bystrov , Vladimir Pekar , Stewart Young , Cornelis Johannes Fransiscus Maria Bergmans , Arianne Van Muiswinkel
发明人： Daniel Bystrov , Vladimir Pekar , Stewart Young , Cornelis Johannes Fransiscus Maria Bergmans , Arianne Van Muiswinkel
IPC分类号： G06K9/00 , G01V3/00 , A61B5/05
CPC分类号： G01R33/54 , G01R33/543 , G06T7/74 , G06T2207/30004 , G06T2207/30244
摘要： A method, an apparatus and a computer program for transferring scan geometry between a first region and a second region, similar to the first region includes identifying the first and second regions in an overview image, followed by determining of the first scan geometry corresponding to the first region. Then, the first scan geometry is transferred into the second scan geometry corresponding to the second region using information on geometrical correspondence between the first and second regions. The transferring includes establishing corresponding mappings between similar regions and their respective scan geometries.
摘要翻译：用于在第一区域和第二区域之间传送扫描几何形状的方法，装置和计算机程序类似于第一区域包括识别概览图像中的第一和第二区域，随后确定对应于第一区。然后，使用关于第一和第二区域之间的几何对应关系的信息将第一扫描几何图形转移到对应于第二区域的第二扫描几何中。转移包括在相似区域和它们各自的扫描几何之间建立相应的映射。

8. 发明申请

US20100100560A1 LEARNING ANATOMY DEPENDENT VIEWING PARAMETERS ON MEDICAL VIEWING WORKSTATIONS 审中-公开
标题翻译：在医疗观察工作台学习解剖学依据查看参数
公开(公告)号：US20100100560A1
公开(公告)日：2010-04-22
申请号：US12531695
申请日：2008-03-28
申请人： Daniel Bystrov , Stewart Young , Vladimir Pekar , Christian Adrian Cocosco
发明人： Daniel Bystrov , Stewart Young , Vladimir Pekar , Christian Adrian Cocosco
IPC分类号： G06F17/30 , G06F3/048
CPC分类号： G06T19/00 , G06F19/321 , G06T2210/41
摘要： The invention relates to a data processing apparatus and a method for providing visualisation parameters controlling the display of a medical image (12). The data processing apparatus comprises a mapping component (16). The mapping component (16) is arranged to receive a current dataset (15) corresponding to the medical image and comprising a content description thereof, to compare the content description of the current dataset (15) with a content description of a plurality of stored datasets, to select at least one further dataset out of the plurality of stored datasets, to retrieve stored visualisation parameters corresponding to the at least one further dataset, and to prepare the retrieved visualisation parameters as the visualisation parameters controlling the display of the medical image (12).
摘要翻译：本发明涉及一种用于提供控制医学图像（12）的显示的可视化参数的数据处理装置和方法。数据处理装置包括映射组件（16）。映射组件（16）被布置成接收与医学图像相对应的当前数据集（15）并且包括其内容描述，以将当前数据集（15）的内容描述与多个存储数据集的内容描述进行比较从多个存储的数据集中选择至少一个另外的数据集，以检索存储的与所述至少一个另外的数据集相对应的可视化参数，并且准备所检索的可视化参数作为控制医学图像显示的可视化参数（12 ）。

9. 发明申请

US20090208105A1 METHOD, AN APPARATUS, A SYSTEM AND A COMPUTER PROGRAM FOR TRANSFERRING SCAN GEOMETRY BETWEEN SUBSEQUENT SCANS 有权
标题翻译：方法，设备，系统和计算机程序，用于传输下一代扫描之间的扫描几何
公开(公告)号：US20090208105A1
公开(公告)日：2009-08-20
申请号：US12307620
申请日：2007-06-28
申请人： Daniel Bystrov , Vladimir Pekar , Stewart Young , Cornelis Johannes Fransiscus Maria Bergmans , Arianne Van Muiswinkel
发明人： Daniel Bystrov , Vladimir Pekar , Stewart Young , Cornelis Johannes Fransiscus Maria Bergmans , Arianne Van Muiswinkel
IPC分类号： G06K9/34 , G06K9/00
CPC分类号： G01R33/54 , G01R33/543 , G06T7/74 , G06T2207/30004 , G06T2207/30244
摘要： The invention relates to a method, an apparatus and a computer program for transferring scan geometry between a first region and a second region, similar to the first region. In the method according to the invention the first region and the second region are being identified (4), preferably in the overview image, followed by determination (6) of the first scan geometry corresponding to the first region. Then, the first scan geometry is being transferred into the second scan geometry corresponding to the second region, whereby information on geometrical correspondence between the first region and the second region is used. Preferably, the step of transferring comprises establishing corresponding mappings between similar regions and their respective scan geometries.
摘要翻译：本发明涉及一种用于在第一区域和第二区域之间传送扫描几何形状的方法，装置和计算机程序，类似于第一区域。在根据本发明的方法中，优选地在概述图像中识别第一区域和第二区域（4），随后确定对应于第一区域的第一扫描几何形状（6）。然后，第一扫描几何被转移到对应于第二区域的第二扫描几何中，由此使用关于第一区域和第二区域之间的几何对应关系的信息。优选地，传送步骤包括在相似区域和它们各自的扫描几何之间建立对应的映射。

10. 发明申请

US20120035463A1 AUTOMATED ANATOMY DELINEATION FOR IMAGE GUIDED THERAPY PLANNING 有权
标题翻译：自动化解剖图像指导治疗计划
公开(公告)号：US20120035463A1
公开(公告)日：2012-02-09
申请号：US13260735
申请日：2010-03-02
申请人： Vladimir Pekar , Daniel Bystrov
发明人： Vladimir Pekar , Daniel Bystrov
IPC分类号： A61B5/055 , A61N5/00 , A61N7/00 , A61B6/03
CPC分类号： A61N5/103 , G06F19/3481 , G16H20/40 , G16H30/20
摘要： When delineating anatomical structures in a medical image of a patient for radiotherapy planning, a processor (18) detects landmarks (24) in a low-resolution image (e.g., MRI or low-dose CT) and maps the detected landmarks to reference landmarks (28) in a reference contour of the anatomical structure. The mapped landmarks facilitate adjusting the reference contour to fit the anatomical structure. The adjusted reference contour data is transformed and applied to a second image using a thin-plate spline, and the adjusted high-resolution image is used for radiotherapy planning.
摘要翻译：当描绘用于放射治疗规划的患者的医学图像中的解剖结构时，处理器（18）以低分辨率图像（例如，MRI或低剂量CT）检测地标（24），并将检测到的地标映射到参考地标（ 28）在解剖结构的参考轮廓中。映射的标记有助于调整参考轮廓以适应解剖结构。使用薄板样条将调整后的参考轮廓数据变换并应用于第二图像，并且将调整后的高分辨率图像用于放射治疗计划。

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