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1. 发明授权

US09486126B2 Endoscopic helix tissue grasping device 有权
标题翻译：内窥镜螺旋组织抓取装置
公开(公告)号：US09486126B2
公开(公告)日：2016-11-08
申请号：US13539777
申请日：2012-07-02
申请人： Stephen West , David Miller , Vladimir Mitelberg , Donald K. Jones
发明人： Stephen West , David Miller , Vladimir Mitelberg , Donald K. Jones
IPC分类号： A61B17/062 , A61B1/018 , A61B17/04 , A61B1/04 , A61B17/06 , A61B17/068 , A61B17/00 , A61B17/064 , A61B17/29
CPC分类号： A61B1/018 , A61B1/04 , A61B17/00234 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/0491 , A61B17/06123 , A61B17/0625 , A61B17/068 , A61B2017/00296 , A61B2017/00349 , A61B2017/0042 , A61B2017/00477 , A61B2017/0409 , A61B2017/0417 , A61B2017/0454 , A61B2017/0464 , A61B2017/0496 , A61B2017/06047 , A61B2017/0608 , A61B2017/0649 , A61B2017/2912
摘要： An endoscopic tissue grasper device includes a flexible tubular member, a flexible shaft extending through the tubular member, a proximal handle for moving the shaft and tubular member relative to each other, and a distal helical coil having a sharpened end for engaging tissue. The helical coil has a proximal close wound portion, a distal open wound portion, and an intermediate transition portion between the proximal and distal portions. The flexible shaft extends into the proximal and intermediate portions and is secured thereto, which prevents tissue engaged by the helical coil from becoming wedged in the transition portion and thereby facilitates release of the coil from engaged tissue. In addition, a bearing sheath is provided between the shaft and tubular member to prevent the shaft from binding during operation.
摘要翻译：内窥镜组织抓取装置包括柔性管状构件，延伸穿过管状构件的柔性轴，用于相对于彼此移动轴和管状构件的近侧手柄，以及具有用于接合组织的尖端的远端螺旋线圈。螺旋线圈具有近端紧密缠绕部分，远端开口缠绕部分以及近端部分和远端部分之间的中间过渡部分。柔性轴延伸到近侧和中间部分并且固定到其上，这防止由螺旋线圈接合的组织楔入过渡部分，从而有助于将线圈从接合的组织释放。此外，在轴和管状构件之间设置有轴承护套以防止轴在操作期间装订。

2. 发明申请

US20130006287A1 Endoscopic Helix Tissue Grasping Device 有权
标题翻译：内窥镜螺旋组织抓取装置
公开(公告)号：US20130006287A1
公开(公告)日：2013-01-03
申请号：US13539777
申请日：2012-07-02
申请人： Stephen West , David Miller , Vladimir Mitelberg , Donald K. Jones
发明人： Stephen West , David Miller , Vladimir Mitelberg , Donald K. Jones
IPC分类号： A61B17/94
CPC分类号： A61B1/018 , A61B1/04 , A61B17/00234 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/0491 , A61B17/06123 , A61B17/0625 , A61B17/068 , A61B2017/00296 , A61B2017/00349 , A61B2017/0042 , A61B2017/00477 , A61B2017/0409 , A61B2017/0417 , A61B2017/0454 , A61B2017/0464 , A61B2017/0496 , A61B2017/06047 , A61B2017/0608 , A61B2017/0649 , A61B2017/2912
摘要： An endoscopic tissue grasper device includes a flexible tubular member, a flexible shaft extending through the tubular member, a proximal handle for moving the shaft and tubular member relative to each other, and a distal helical coil having a sharpened end for engaging tissue. The helical coil has a proximal close wound portion, a distal open wound portion, and an intermediate transition portion between the proximal and distal portions. The flexible shaft extends into the proximal and intermediate portions and is secured thereto, which prevents tissue engaged by the helical coil from becoming wedged in the transition portion and thereby facilitates release of the coil from engaged tissue. In addition, a bearing sheath is provided between the shaft and tubular member to prevent the shaft from binding during operation.
摘要翻译：内窥镜组织抓取装置包括柔性管状构件，延伸穿过管状构件的柔性轴，用于相对于彼此移动轴和管状构件的近侧手柄，以及具有用于接合组织的尖端的远端螺旋线圈。螺旋线圈具有近端紧密缠绕部分，远侧开口缠绕部分以及近端部分和远端部分之间的中间过渡部分。柔性轴延伸到近侧和中间部分并且固定到其上，这防止由螺旋线圈接合的组织楔入过渡部分，从而有助于将线圈从接合的组织释放。此外，在轴和管状构件之间设置有轴承护套以防止轴在操作期间装订。

3. 发明申请

US20120271327A1 Endoscopic Tissue Grasping Systems and Methods 审中-公开
标题翻译：内镜组织抓取系统和方法
公开(公告)号：US20120271327A1
公开(公告)日：2012-10-25
申请号：US13539661
申请日：2012-07-02
申请人： Stephen West , David Miller , Vladimir Mitelberg , Donald K. Jones
发明人： Stephen West , David Miller , Vladimir Mitelberg , Donald K. Jones
IPC分类号： A61B17/04
CPC分类号： A61B1/018 , A61B1/04 , A61B17/00234 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/0491 , A61B17/06123 , A61B17/0625 , A61B17/068 , A61B2017/00296 , A61B2017/00349 , A61B2017/0042 , A61B2017/00477 , A61B2017/0409 , A61B2017/0417 , A61B2017/0454 , A61B2017/0464 , A61B2017/0496 , A61B2017/06047 , A61B2017/0608 , A61B2017/0649 , A61B2017/2912
摘要： An endoscopic tissue grasper device includes a flexible tubular member, a flexible shaft extending through the tubular member, a proximal handle for moving the shaft and tubular member relative to each other, and a distal helical coil having a sharpened end for engaging tissue. The tissue grasper is advanced through a working channel of an endoscope, engaged relative to tissue, and retracted to pull tissue into a path of a movable needle coupled at a distal end of the endoscope so that the needle can be passed through the tissue. The needle is preferably provided with a suture so that as the needle is passed through the tissue a stitch is formed.
摘要翻译：内窥镜组织抓取装置包括柔性管状构件，延伸穿过管状构件的柔性轴，用于相对于彼此移动轴和管状构件的近侧手柄，以及具有用于接合组织的尖端的远端螺旋线圈。组织抓取器前进通过内窥镜的工作通道，相对于组织接合并且缩回以将组织拉入连接在内窥镜的远端的可移动针的路径，使得针可以穿过组织。针优选地设置有缝合线，使得当针穿过组织时，形成线迹。

4. 发明授权

US11083364B2 Endoscopic tissue grasping systems and methods 有权
公开(公告)号：US11083364B2
公开(公告)日：2021-08-10
申请号：US13539661
申请日：2012-07-02
申请人： Stephen West , David Miller , Vladimir Mitelberg , Donald K. Jones
发明人： Stephen West , David Miller , Vladimir Mitelberg , Donald K. Jones
IPC分类号： A61B1/018 , A61B17/04 , A61B1/04 , A61B17/06 , A61B17/062 , A61B17/068 , A61B17/00 , A61B17/064 , A61B17/29
摘要： An endoscopic tissue grasper device includes a flexible tubular member, a flexible shaft extending through the tubular member, a proximal handle for moving the shaft and tubular member relative to each other, and a distal helical coil having a sharpened end for engaging tissue. The tissue grasper is advanced through a working channel of an endoscope, engaged relative to tissue, and retracted to pull tissue into a path of a movable needle coupled at a distal end of the endoscope so that the needle can be passed through the tissue. The needle is preferably provided with a suture so that as the needle is passed through the tissue a stitch is formed.

5. 发明授权

US11007416B2 Pickleball barrier 有权
公开(公告)号：US11007416B2
公开(公告)日：2021-05-18
申请号：US16406636
申请日：2019-05-08
申请人： David Miller
发明人： David Miller
IPC分类号： A63B71/02 , E04H17/16 , A63B69/00
摘要： A deployable pickleball barrier includes a plurality of panels having a first rigid surface, a second rigid surface, and a substantially straight channel coupling the rigid surfaces. Each of the plurality of panels are coupled with another of the plurality of panels by an interpanel joint that includes a rigid bond and a plurality of fold lines formed in the first rigid surface to form a rightwardly biasing hinge. Each of the plurality of panels includes an intrapanel joint including a plurality of fold lines formed in the second rigid surface to form a leftwardly biasing hinge. The deployable pickleball barrier can be folded at each of the hinges to alternate between a deployed configuration and a folded configuration.

6. 发明授权

US10363087B2 Tissue resection device 有权
公开(公告)号：US10363087B2
公开(公告)日：2019-07-30
申请号：US12902747
申请日：2010-10-12
申请人： David Miller , Todd Dalton , Mitch Gilkey
发明人： David Miller , Todd Dalton , Mitch Gilkey
IPC分类号： A61B18/14
摘要： Instruments and methods are provided for performing submucosal medical procedures in a desired area of the digestive tract using endoscopy. The instruments include a mucosal resection device, a tissue grasper and a snare. Systems include a combination of one or more of such instruments. Embodiments of various methods for performing the procedures are also provided.

7. 发明授权

US09584496B2 Systems and methods for securely monitoring an individual 有权
标题翻译：用于安全监控个人的系统和方法
公开(公告)号：US09584496B2
公开(公告)日：2017-02-28
申请号：US13497123
申请日：2012-09-05
申请人： Rick V. Murakami , David Miller , Matthew W. Pettit , Larry V. Lunt
发明人： Rick V. Murakami , David Miller , Matthew W. Pettit , Larry V. Lunt
IPC分类号： G05B19/00 , G06F7/00 , G08B29/00 , H04L9/00 , H04L29/06 , G06F21/32 , G06F21/34 , G06F21/62 , G06K9/00 , H04M1/67
CPC分类号： H04L63/08 , G06F21/32 , G06F21/34 , G06F21/6245 , G06K9/00885 , G06K9/00979 , H04L63/166 , H04M1/67
摘要： A biometric sensor may be coupled to a portable communications device, such as a cellular telephone. The biometric sensor may be configured to acquire one or more measurements of biological characteristics of an individual. One or more of the measurements may relate to internal, sub-epidermal characteristics of the individual, such as non-volitional processes occurring within the individual, sub-epidermal structures within the individual, or the like. A biometric marker may be derived from one or more of the measurements. The portable communications device may be activated responsive to deriving the biometric marker. The activation may include transmitting the measurements and/or biometric markers derived therefrom to a receiver using the portable communications device.
摘要翻译：生物测定传感器可以耦合到诸如蜂窝电话的便携式通信设备。生物测定传感器可以被配置为获取个体的生物学特征的一个或多个测量值。一个或多个测量可以涉及个体的内部，亚表皮特征，例如个体内发生的非传染性过程，个体内的亚表皮结构等。可以从一个或多个测量中导出生物特征标记。可以响应于导出生物特征标记来激活便携式通信设备。激活可以包括使用便携式通信设备将从其导出的测量和/或生物测定标记传送到接收机。

8. 发明申请

US20160333585A1 GLAZING PANEL ROOFING SYSTEM 有权
标题翻译：玻璃面板系统
公开(公告)号：US20160333585A1
公开(公告)日：2016-11-17
申请号：US15153521
申请日：2016-05-12
申请人： David Miller , Frank Kosciolek
发明人： David Miller , Frank Kosciolek
IPC分类号： E04D13/03 , F16B33/00 , F16B25/10
CPC分类号： E04D3/08 , E04D2003/0818 , E04D2003/0856 , F16B25/10 , F16B2005/0678
摘要： A glazing panel roofing system includes a glazing panel and glazing panel brackets configured to clamp upon one of the side edge surfaces of the glazing panel. The glazing panel includes two flat face surfaces and two side edge surfaces. The glazing panel brackets are configured to clamp upon one of the side edge surfaces of the glazing panel. Each glazing panel bracket includes a base clamping feature including a base gripping feature surface configured to abut a first surface of the flat face surfaces, a top clamping feature including a top gripping feature surface configured to abut a second surface of the flat face surfaces, and a threaded fastener securing the top clamping feature to the base clamping feature, wherein torque applied to the threaded fastener changes a clamping force applied between the top clamping feature and the base clamping feature upon the glazing panel.
摘要翻译：玻璃幕墙屋顶系统包括玻璃板和玻璃板支架，其构造成夹紧在玻璃板的一个侧边缘表面上。上光板包括两个平面表面和两个侧边缘表面。玻璃板支架被配置为夹紧玻璃板的一个侧边缘表面。每个上光板托架包括基部夹紧特征，其包括构造成邻接平坦表面的第一表面的基部夹持特征表面，顶部夹持特征，包括构造成邻接平坦表面的第二表面的顶部抓握特征表面，以及将顶部夹紧特征固定到基部夹紧特征的螺纹紧固件，其中施加到螺纹紧固件的扭矩将施加在顶部夹紧特征和基部夹持特征之间的夹紧力改变在玻璃板上。

9. 发明授权

US09290456B2 Pyridazinone compounds and their use as DAAO inhibitors 有权
标题翻译：哒嗪酮化合物及其作为DAAO抑制剂的用途
公开(公告)号：US09290456B2
公开(公告)日：2016-03-22
申请号：US14240045
申请日：2012-08-21
申请人： William Farnaby , Charlotte Fieldhouse , Katherine Hazel , Catrina Kerr , Natasha Kinsella , David Livermore , Kevin Merchant , David Miller
发明人： William Farnaby , Charlotte Fieldhouse , Katherine Hazel , Catrina Kerr , Natasha Kinsella , David Livermore , Kevin Merchant , David Miller
IPC分类号： C07D237/16 , C07D401/06 , A61K31/50 , A61K31/501 , C07D401/10 , C07D407/10 , A61K45/06 , C07D237/18 , C07D237/22 , C07D405/06 , C07F7/08
CPC分类号： A61K31/50 , A61K31/501 , A61K45/06 , C07D237/16 , C07D237/18 , C07D237/22 , C07D401/06 , C07D401/10 , C07D405/06 , C07D407/10 , C07F7/0812
摘要： The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1 and R2 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
摘要翻译：本发明提供式（I）化合物及其药学上可接受的盐，其中R1和R2如说明书中所定义，其制备方法，含有它们的药物组合物及其在治疗中的用途。

10. 发明授权

US09101735B2 Catheter control systems 有权
标题翻译：导管控制系统
公开(公告)号：US09101735B2
公开(公告)日：2015-08-11
申请号：US12499011
申请日：2009-07-07
申请人： Chris A. Rothe , Juan Diego Perea , David Miller , Vahid Saadat , Zachary J. Malchano , Ruey-Feng Peh
发明人： Chris A. Rothe , Juan Diego Perea , David Miller , Vahid Saadat , Zachary J. Malchano , Ruey-Feng Peh
IPC分类号： A61B1/01 , A61M25/01 , A61M25/00
CPC分类号： A61M25/0147 , A61M25/0074 , A61M25/0082 , A61M25/0105 , A61M25/0136 , A61M2025/015
摘要： Catheter control systems which facilitate the tracking of an angle of deflection of a catheter distal end can be used for any number of procedures where catheter orientation relative to the body is desirable, e.g., in transseptal access procedures where an accurate angle of puncture of the septal wall is desirable. Such control systems may comprise a steerable handle which is oriented relative to the catheter steerable section to provide for consistent catheter articulation upon corresponding manipulation of the steering ring. Another variation may utilize an orientation indicator to track the deflectable distal end. For instance, an orientation marker as visualized through an imaging hood on the distal end may correspond to identical orientation markers on the control handle such that articulation of a steering mechanism in a direction relative to the orientation markers deflects the catheter distal end in a corresponding direction relative to the visualized orientation markers.
摘要翻译：促进跟踪导管远端的偏转角度的导管控制系统可用于任何数量的程序，其中导管相对于身体的取向是期望的，例如在中间通道的准确的穿刺角度墙是理想的。这样的控制系统可以包括相对于导管可转向部分定向的可操纵手柄，以在相应操纵转向环时提供一致的导管关节运动。另一种变型可以利用取向指示器来跟踪可偏转的远端。例如，通过远端上的成像罩可视化的取向标记可以对应于控制手柄上的相同的取向标记，使得转向机构在相对于定向标记的方向上的关节转动导管远端在相应方向相对于可视化的取向标记。

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