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1. 发明申请

US20160151016A1 METHODS FOR DEFINING AEROBIC EXERCISE TRAINING ZONES FOR USE IN AN EXERCISE TRAINING PRESCRIPTION AND FOR PROVIDING FEEDBACK ON COMPLIANCE WITH THE PRESCRIPTION 审中-公开
标题翻译：用于定义运动训练课程中使用的急性练习训练区的方法，并提供符合规定的反馈
公开(公告)号：US20160151016A1
公开(公告)日：2016-06-02
申请号：US14308202
申请日：2014-06-18
申请人： Stephen T. Anderson , David Anderson , Bruce D. Johnson , Dianna Orr
发明人： Stephen T. Anderson , David Anderson , Bruce D. Johnson , Dianna Orr
IPC分类号： A61B5/00 , A61B5/0205 , A63B24/00
CPC分类号： A61B5/4866 , A61B5/024 , A61B5/0833 , A61B5/0836 , A61B5/4884 , A61B2503/10
摘要： A method of pattern recognition for defining aerobic HR training zones measured during incremental cardiopulmonary exercise testing wherein such HR training zones are derived from distinct points in the incremental exercise response for % fat, % CHO, and PetCO2. Also disclosed is a method for providing feedback to the exercising subject indicating the % time the subject exercised in each of the zones using recorded HR data from each workout.
摘要翻译：一种用于定义在增量心肺运动测试期间测量的有氧人力资源训练区域的模式识别方法，其中所述HR训练区域来自％脂肪，％CHO和PetCO2的递增运动反应中的不同点。还公开了一种用于向运动对象提供反馈的方法，其使用来自每次锻炼的记录的HR数据来指示在每个区域中运动的受试者的时间。

2. 发明授权

US08630811B2 Method for combining individual risk variables derived from cardiopulmonary exercise testing into a single variable 有权
标题翻译：将来自心肺运动测试的个体风险变量组合成单个变量的方法
公开(公告)号：US08630811B2
公开(公告)日：2014-01-14
申请号：US13533519
申请日：2012-06-26
申请人： Stephen T. Anderson , Dean J. MacCarter , Bruce D. Johnson
发明人： Stephen T. Anderson , Dean J. MacCarter , Bruce D. Johnson
IPC分类号： G06F19/00 , A61B5/08
CPC分类号： A61B5/4884 , A61B5/02028 , A61B5/0205 , A61B5/024 , A61B5/0833 , A61B5/0836 , A61B5/14542 , A61B5/221 , A61B5/7264 , A61B5/7275 , G06F19/00 , G06F19/3481 , G16H15/00 , G16H50/20
摘要： A method of pattern recognition for classifying the functional status of patients with chronic disease comprising characterizing the functional status based on a multivariable index (MVI) scoring system wherein the MVI is computed by summing a plurality of individual variable values as individual variable indexes (IVI) and dividing the sum by the number of variables and wherein the plurality of IVI includes rest PetCO2, ΔPetCO2, SaO2, QUES, Ve/VCO2 slope and Pcap and wherein each IVI is given an equivalent value of =4.00, the number increasing with increasing severity yielding an MVI value ranging from =4.00, normal to severe-very severe.
摘要翻译：一种用于分类患有慢性疾病的患者的功能状态的模式识别方法，包括基于多变量指数（MVI）评分系统表征功能状态，其中通过将多个个体变量值相加作为个体变量指数（IVI）来计算MVI，并且将所述和除以所述变量的数量，并且其中所述多个IVI包括休息PetCO2，DeltaPetCO2，SaO2，QUES，Ve / VCO2斜率和Pcap，并且其中每个IVI被给予等于<1.00至> = 4.00的值，随着严重程度的增加而增加，MVI值范围从<1.00>> 4.00，正常至严重非常严重。

3. 发明申请

US20120265447A1 METHOD FOR COMBINING INDIVIDUAL RISK VARIABLES DERIVED FROM CARDIOPULMONARY EXERCISE TESTING INTO A SINGLE VARIABLE 有权
标题翻译：将个体风险变量组合起来的方法从心脏运动测试转换为单变量
公开(公告)号：US20120265447A1
公开(公告)日：2012-10-18
申请号：US13533519
申请日：2012-06-26
申请人： Stephen T. Anderson , Dean J. MacCarter , Bruce D. Johnson
发明人： Stephen T. Anderson , Dean J. MacCarter , Bruce D. Johnson
IPC分类号： G06F19/00
CPC分类号： A61B5/4884 , A61B5/02028 , A61B5/0205 , A61B5/024 , A61B5/0833 , A61B5/0836 , A61B5/14542 , A61B5/221 , A61B5/7264 , A61B5/7275 , G06F19/00 , G06F19/3481 , G16H15/00 , G16H50/20
摘要： A method of pattern recognition for classifying the functional status of patients with chronic disease comprising characterizing the functional status based on a multivariable index (MVI) scoring system wherein the MVI is computed by summing a plurality of individual variable values as individual variable indexes (IVI) and dividing the sum by the number of variables and wherein the plurality of IVI includes rest PetCO2, ΔPetCO2, SaO2, QUES, Ve/VCO2 slope and Pcap and wherein each IVI is given an equivalent value of =4.00, the number increasing with increasing severity yielding an MVI value ranging from =4.00, normal to severe-very severe.
摘要翻译：一种用于分类患有慢性疾病的患者的功能状态的模式识别方法，包括基于多变量指数（MVI）评分系统表征功能状态，其中通过将多个个体变量值相加作为个体变量指数（IVI）来计算MVI，并且将所述和除以所述变量的数量，并且其中所述多个IVI包括剩余的PetCO2，Dgr; PetCO2，SaO2，QUES，Ve / VCO2斜率和Pcap，并且其中每个IVI被给予等价值<1.00至> = 4.00，该数字随着严重程度的增加而增加，产生从<1.00至> = 4.00的MVI值，正常至严重非常严重。

4. 发明授权

US08768463B2 Method of defining continuous heart rate vs AV delay values and sensed to paced AV delay offset in patients undergoing cardiac resynchronization therapy 有权
标题翻译：在进行心脏再同步治疗的患者中定义连续心率与AV延迟值并感测到起搏AV延迟偏移的方法
公开(公告)号：US08768463B2
公开(公告)日：2014-07-01
申请号：US12944001
申请日：2010-11-11
申请人： Stephen T. Anderson , Dean J. MacCarter
发明人： Stephen T. Anderson , Dean J. MacCarter
IPC分类号： A61N1/37
CPC分类号： A61N1/3682 , A61N1/3627
摘要： A method of data management for optimizing the patient outcome from the provision of cardiac resynchronization therapy (CRT) is described. A regression equation is constructed using 3 data points on a plot of AV delay vs. HR. The x-axis consist of the three points consist of resting HR, HR at the optimal AV delay value during light exercise, and the upper tracking or paced HR. The y-values associated with the three points consist of the AV delay values computed using an equation for ventricular filling time and the optimally determined AV delay value. Also described is a process for determining the sensed to paced AV delay offset. The combined processes yield 4 (the three constant values in the polynomial regression equation Y=b2X2+b1X+a and the sensed to paced AV delay offset) which can be stored on the patient's pacemaker for determining dynamically the AV delay value which is physiologically fine-tuned for each patient from resting HR to the upper tracking or paced HR. In combination with visual observation and computer-assisted ranking of the dependent variables, a physician can utilize the resulting information to render decisions on the optimal choice of the programming biventricular pacemakers/ICDs and DDDR pacemakers for individual patients.
摘要翻译：描述了一种用于从提供心脏再同步治疗（CRT）中优化患者结果的数据管理方法。在AV延迟与HR的图上使用3个数据点构建回归方程。 x轴由休息HR，轻度运动期间最佳AV延迟值处的HR以及上跟踪或起搏HR组成的三个点组成。与三点相关联的y值包括使用用于心室充盈时间的方程和最佳确定的AV延迟值计算的AV延迟值。还描述了一种用于确定感测到的起搏AV延迟偏移的过程。组合过程产生4（多项式回归方程中的三个常数值Y = b2X2 + b1X + a和感测到的AV延迟偏移），其可以存储在患者起搏器上以动态地确定生理学上良好的AV延迟值将每个患者的休息时间从静息HR调整到上部跟踪或节奏的HR。结合视觉观察和计算机辅助排列的因变量，医师可以利用所得到的信息来对个体患者的双心室起搏器/ ICD和DDDR起搏器编程的最佳选择作出决定。

5. 发明授权

US5410472A Method for conditioning or rehabilitating using a prescribed exercise program 失效
标题翻译：使用规定的锻炼计划进行调理或康复的方法
公开(公告)号：US5410472A
公开(公告)日：1995-04-25
申请号：US967357
申请日：1992-10-27
申请人： Stephen T. Anderson
发明人： Stephen T. Anderson
IPC分类号： A63B21/005 , A63B21/22 , A63B24/00 , G06F19/00 , G06F15/00
CPC分类号： A63B21/00181 , A63B24/00 , G06F19/3481 , A63B21/0058 , A63B21/225 , A63B2220/34 , A63B2220/54 , A63B2230/04 , A63B2230/30 , A63B2230/433 , A63B2230/436 , A63B24/0075 , G06F19/322 , Y10S482/90
摘要： A distributive method of physical rehabilitation and conditioning using an ergometer on which exercise protocols or workouts are performed by a subject is described. The intensity and duration of the workouts are defined as the independent variables and physiological and psychological variables are measured and treated as dependent variables. The exercise protocol is stored on a portable medium and the exercise program further defines a series of successive exercise sessions conducted over time in which the same exercise protocol is repeatedly performed by the subject; and, during the performance of which protocol, physiological and psychological variables are measured. The relative changes in one or more of the dependent variables which occur over the course of the series of sessions of the exercise training program measure progress and provide the basis for modification of the exercise protocol for the next exercise training program for that subject.
摘要翻译：描述使用由受试者执行运动协议或锻炼的测力计进行身体康复和调理的分布方法。锻炼的强度和持续时间被定义为独立变量，生理和心理变量被测量并作为因变量来处理。运动方案被存储在便携式介质上，并且运动程序进一步限定了随着时间的推移进行的一系列连续的运动会话，其中相同的运动协议被主体反复执行; 并且在执行哪个协议期间，测量生理和心理变量。运动训练计划的一系列会议期间发生的一个或多个因变量的相对变化衡量进展情况，并为下一次该项目的运动训练计划修改运动方案提供依据。

6. 发明申请

US20100016750A1 Pattern Recognition System for Classifying the Functional Status of Patients with Pulmonary Hypertension, Including Pulmonary Arterial and Pulmonary Vascular Hypertension 有权
标题翻译：用于分类肺动脉高压患者功能状态的模式识别系统，包括肺动脉和肺动脉高压
公开(公告)号：US20100016750A1
公开(公告)日：2010-01-21
申请号：US12567005
申请日：2009-09-25
申请人： Stephen T. Anderson , Dean J. MacCarter
发明人： Stephen T. Anderson , Dean J. MacCarter
IPC分类号： A61B5/08
CPC分类号： G06F19/3431 , A61B5/00 , A61B5/0205 , A61B5/024 , A61B5/0833 , A61B5/0836 , A61B5/4884 , A61B5/7264 , A61B5/7275 , G06F19/00 , G16H15/00 , G16H50/30
摘要： A method employing pattern recognition techniques for identifying the functional status of patients with Pulmonary Hypertension is described. This method describes a process by which sets of cardiopulmonary exercise gas exchange variables are measured during rest, exercise and recovery and stored as unique data sets. The data sets are then analyzed by a series of feature extraction steps, yielding a multi-parametric index (MPIPH) which reflects the current functional status of a patient. The method also employs a description scheme that provides a graphical image that juxtaposes the measured value of MPI to a reference classification system. An additional description scheme provides a trend plot of MPI values measured on a patient over time to provide feedback to the physician on the efficacy of therapy provided to the patient. The method will enable physicians to gather, view, and track complicated data using well-understood visualization techniques to better understand the consequences of their therapeutic actions.
摘要翻译：描述了采用模式识别技术识别肺动脉高压患者功能状态的方法。该方法描述了在休息，运动和恢复期间测量心肺运动气体交换变量的集合并作为唯一数据集存储的过程。然后通过一系列特征提取步骤分析数据集，产生反映患者当前功能状态的多参数指数（MPIPH）。该方法还采用描述方案，其提供将参考分类系统的MPI的测量值并置的图形图像。额外的描述方案提供了随着时间的推移在患者身上测量的MPI值的趋势图，以向医师提供关于提供给患者的疗效的反馈。该方法将使医师能够使用熟悉的可视化技术来收集，查看和跟踪复杂的数据，以更好地了解其治疗行为的后果。

7. 发明授权

US4463764A Cardiopulmonary exercise system 失效
标题翻译：心肺运动系统
公开(公告)号：US4463764A
公开(公告)日：1984-08-07
申请号：US306607
申请日：1981-09-29
申请人： Stephen T. Anderson , Catherine A. Anderson , Terrance J. Kapsen
发明人： Stephen T. Anderson , Catherine A. Anderson , Terrance J. Kapsen
IPC分类号： A61B5/22 , G06F19/00 , A61B5/08
CPC分类号： A61B5/222 , G06F19/3487 , G06F19/3406
摘要： A cardiopulmonary exercise system for real-time, breath-by-breath acquisition, analysis, display and printing of an individual's physiologic parameters. A microprocessor based waveform analyzer receives inputs from a CO.sub.2 analyzer, an ECG monitor, an O.sub.2 analyzer, and a pneumotachograph, and, optionally, can also connect a cycle ergometer, a treadmill, a cardiac stress system, and an ear oximeter. The waveform analyzer provides output data to a host central processor unit to which a CRT display, a graphics copier or hard-copy printer may be connected for providing medical data for assessment of an individual's heart and lungs, on a real-time basis whereby the level of fitness or underlying organic defects which may effect the cardiopulmonary system can be determined. The pneumotachograph, CO.sub.2 analyzer and O.sub.2 analyzer and ECG monitor provide analog signals representing flow, CO.sub.2 and O.sub.2 levels in expired air as well as heart rate. The waveform analyzer, under control of its dedicated microprocessor, performs an A/D conversion with the microprocessor also being used to calculate the tidal volume (V.sub.T), minute ventilation (V.sub.E), breathing frequency (f.sub.B), cardiac frequency (f.sub.C), inspiratory time (T.sub.I) and total time (T.sub.TOT) of last breath, fraction of CO.sub.2 in inspired gas (F.sub.ICO.sbsb.2) and fraction of O.sub.2 in inspired gas (F.sub.IO.sbsb.2), peak CO.sub.2 and O.sub.2 (F.sub.ETCO.sbsb.2 and F.sub.ETO.sbsb.2), and expired volumes of CO.sub.2 and O.sub.2 (VCO.sub.2 and VO.sub.2) breath-by-breath. The system of the preferred embodiment analyzes the individual's expirate at a sample rate of one hundred samples per second per channel with twelve bit resolution.
摘要翻译：一种心肺运动系统，用于实时，呼吸采集，分析，显示和打印个人的生理参数。基于微处理器的波形分析仪接收来自CO 2分析仪，ECG监测器，O 2分析仪和气动示波器的输入，并且还可以连接循环测力计，跑步机，心脏应激系统和耳鸣计。波形分析仪将输出数据提供给主机中央处理器单元，CRT显示器，图形复印机或硬拷贝打印机可以连接到主机中央处理器单元，用于提供用于个人心脏和肺部的评估的医疗数据，可以确定可能影响心肺系统的适应度或潜在的有机缺陷水平。气压示波器，CO2分析仪和O2分析仪和ECG监测器提供模拟信号，表示呼出空气中的流量，CO2和O2水平以及心率。波形分析仪在其专用微处理器的控制下进行A / D转换，微处理器也用于计算潮气量（VT），分钟通气（VE），呼吸频率（fB），心脏频率（fC）吸气时间（TI）和总时间（TTOT），吸入气体中二氧化碳分数（FICO2）和O2在吸入气体（FIO2），CO2和O2（FETCO2和FETO2）峰值中的分数，以及过量体积的二氧化碳和O2（VCO2和VO2）呼吸呼吸。优选实施例的系统以12位分辨率以每通道每秒100个样本的采样率分析个人的到期时间。

8. 发明授权

US08775093B2 Pattern recognition system for classifying the functional status of patients with pulmonary hypertension, including pulmonary arterial and pulmonary vascular hypertension 有权
标题翻译：用于分类肺动脉高压患者功能状态的模式识别系统，包括肺动脉和肺动脉高压
公开(公告)号：US08775093B2
公开(公告)日：2014-07-08
申请号：US12567005
申请日：2009-09-25
申请人： Stephen T. Anderson , Dean J. MacCarter
发明人： Stephen T. Anderson , Dean J. MacCarter
IPC分类号： G06F19/00 , A61B5/083 , A61B5/091 , A61B5/0205 , A61B5/00
CPC分类号： G06F19/3431 , A61B5/00 , A61B5/0205 , A61B5/024 , A61B5/0833 , A61B5/0836 , A61B5/4884 , A61B5/7264 , A61B5/7275 , G06F19/00 , G16H15/00 , G16H50/30
摘要： A method employing pattern recognition techniques for identifying the functional status of patients with Pulmonary Hypertension is described. This method describes a process by which sets of cardiopulmonary exercise gas exchange variables are measured during rest, exercise and recovery and stored as unique data sets. The data sets are then analyzed by a series of feature extraction steps, yielding a multi-parametric index (MPIPH) which reflects the current functional status of a patient. The method also employs a description scheme that provides a graphical image that juxtaposes the measured value of MPI to a reference classification system. An additional description scheme provides a trend plot of MPI values measured on a patient over time to provide feedback to the physician on the efficacy of therapy provided to the patient. The method will enable physicians to gather, view, and track complicated data using well-understood visualization techniques to better understand the consequences of their therapeutic actions.
摘要翻译：描述了采用模式识别技术识别肺动脉高压患者功能状态的方法。该方法描述了在休息，运动和恢复期间测量心肺运动气体交换变量的集合并作为唯一数据集存储的过程。然后通过一系列特征提取步骤分析数据集，产生反映患者当前功能状态的多参数指数（MPIPH）。该方法还采用描述方案，其提供将参考分类系统的MPI的测量值并置的图形图像。额外的描述方案提供了随着时间的推移在患者身上测量的MPI值的趋势图，以向医师提供关于提供给患者的疗效的反馈。该方法将使医师能够使用熟悉的可视化技术来收集，查看和跟踪复杂的数据，以更好地了解其治疗行为的后果。

9. 发明授权

US07225022B2 Method of optimizing patient outcome from cardiac resynchronization therapy 有权
标题翻译：从心脏再同步治疗优化患者结局的方法
公开(公告)号：US07225022B2
公开(公告)日：2007-05-29
申请号：US10797948
申请日：2004-03-11
申请人： Stephen T. Anderson , Dean J. MacCarter
发明人： Stephen T. Anderson , Dean J. MacCarter
IPC分类号： A61N1/365
CPC分类号： A61N1/36564 , A61B5/083 , A61B5/0833 , A61B5/0836 , A61B5/4884 , A61N1/3627 , A61N1/36557 , A61N1/37252
摘要： A method of data management for optimizing the patient outcome from the provision of cardiac resynchronization therapy (CRT) is described. This method describes a process by which sets of dynamic cardiopulmonary dependent variables are measured during steady-state conditions, displayed, and translated into quantitative and qualitative measurements while the independent variables of CRT, device lead placement and atrial-ventricular and interventricular delay settings of bi-ventricular pacemaker systems, are altered by a physician. In combination with visual observation and computer-assisted ranking of the dependent variables, a physician can utilize the resulting information to render decisions on the optimal choice of the independent variables.
摘要翻译：描述了一种用于从提供心脏再同步治疗（CRT）中优化患者结果的数据管理方法。该方法描述了在稳态条件下测量动态心肺依赖变量集合的过程，显示并转换为定量和定性测量，而CRT，设备引导位置和bi的心室和心室间延迟设置的独立变量室内起搏器系统由医生改变。结合视觉观察和因变量的计算机辅助排名，医生可以利用所得到的信息来对自变量的最佳选择作出决定。

10. 发明申请

US20120123493A1 Method of Defining Continuous Heart Rate vs AV Delay Values and Sensed to Paced AV Delay Offset in Patients Undergoing Cardiac Resynchronization Therapy 有权
标题翻译：在进行心脏再同步治疗的患者中定义连续心率与AV延迟值并感测到平均AV延迟偏移的方法
公开(公告)号：US20120123493A1
公开(公告)日：2012-05-17
申请号：US12944001
申请日：2010-11-11
申请人： Stephen T. Anderson , Dean J. MacCarter
发明人： Stephen T. Anderson , Dean J. MacCarter
IPC分类号： A61N1/365
CPC分类号： A61N1/3682 , A61N1/3627
摘要： A method of data management for optimizing the patient outcome from the provision of cardiac resynchronization therapy (CRT) is described. A regression equation is constructed using 3 data points on a plot of AV delay vs. HR. The x-axis consist of the three points consist of resting HR, HR at the optimal AV delay value during light exercise, and the upper tracking or paced HR. The y-values associated with the three points consist of the AV delay values computed using an equation for ventricular filling time and the optimally determined AV delay value. Also described is a process for determining the sensed to paced AV delay offset. The combined processes yield 4 (the three constant values in the polynomial regression equation Y=b2X2+b1X+a and the sensed to paced AV delay offset) which can be stored on the patient's pacemaker for determining dynamically the AV delay value which is physiologically fine-tuned for each patient from resting HR to the upper tracking or paced HR. In combination with visual observation and computer-assisted ranking of the dependent variables, a physician can utilize the resulting information to render decisions on the optimal choice of the programming biventricular pacemakers/ICDs and DDDR pacemakers for individual patients.
摘要翻译：描述了一种用于从提供心脏再同步治疗（CRT）中优化患者结果的数据管理方法。在AV延迟与HR的图上使用3个数据点构建回归方程。 x轴由休息HR，轻度运动期间最佳AV延迟值处的HR以及上跟踪或起搏HR组成的三个点组成。与三点相关联的y值包括使用用于心室充盈时间的方程和最佳确定的AV延迟值计算的AV延迟值。还描述了一种用于确定感测到的起搏AV延迟偏移的过程。组合过程产生4（多项式回归方程中的三个常数值Y = b2X2 + b1X + a和感测到的AV延迟偏移），其可以存储在患者起搏器上以动态地确定生理学上良好的AV延迟值将每个患者的休息时间从静息HR调整到上部跟踪或节奏的HR。结合视觉观察和计算机辅助排列的因变量，医师可以利用所得到的信息来对个体患者的双心室起搏器/ ICD和DDDR起搏器编程的最佳选择作出决定。

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