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1. 发明申请

US20050171140A1 HMG-CoA reductase inhibitors and method 有权
标题翻译： HMG-CoA还原酶抑制剂及方法
公开(公告)号：US20050171140A1
公开(公告)日：2005-08-04
申请号：US10989138
申请日：2004-11-15
申请人： Stephen O'Connor , Jeffrey Robl , Saleem Ahmad , Sharon Bisaha , Natesan Murugesan , Khehyong Ngu , Yan Shi , Philip Stein , Nachimuthu Soundararajan , Kenneth Natalie , Laxma Kolla , Justin Sausker , Sandra Quinlan , Junying Fan , Dejah Petsch , Zhenrong Guo
发明人： Stephen O'Connor , Jeffrey Robl , Saleem Ahmad , Sharon Bisaha , Natesan Murugesan , Khehyong Ngu , Yan Shi , Philip Stein , Nachimuthu Soundararajan , Kenneth Natalie , Laxma Kolla , Justin Sausker , Sandra Quinlan , Junying Fan , Dejah Petsch , Zhenrong Guo
IPC分类号： A61K31/435 , A61K31/4745 , A61K31/505 , C07D211/76 , C07D213/80 , C07D401/14 , C07D471/02 , C07D471/04 , C07D491/04 , C07D498/04 , C07D513/04
CPC分类号： C07D213/80 , C07D211/76 , C07D401/14 , C07D471/04 , C07D491/04 , C07D498/04 , C07D513/04
摘要： Compounds are provided having the following structure and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, U, V, W, Y, and n are as defined above, which compounds are HMG CoA reductase inhibitors and thus are active in inhibiting cholesterol biosynthesis, modulating blood serum lipids, for example, lowering LDL cholesterol and/or increasing HDL cholesterol, and treating hyperlipidemia, dyslipidemia, hypercholesterolemia, hypertriglyceridemia and atherosclerosis as well as Alzheimer's disease and osteoporosis and may be employed as hormone replacement therapy. A method for treating the above diseases employing the above compounds is also provided.
摘要翻译：提供具有以下结构的化合物及其药学上可接受的盐，其中R 1，R 2，R 3，R 4，其中U，V，W，Y和n如上所定义，这些化合物是HMG CoA还原酶抑制剂，因此具有抑制胆固醇生物合成，调节血清脂质的作用，例如降低LDL胆固醇和/或增加 HDL胆固醇，治疗高脂血症，血脂异常，高胆固醇血症，高甘油三酯血症和动脉粥样硬化以及阿尔茨海默病和骨质疏松症，可用作激素替代疗法。还提供了使用上述化合物治疗上述疾病的方法。

2. 发明授权

US08488651B1 Encoding scheme for data transfer 有权
标题翻译：数据传输编码方案
公开(公告)号：US08488651B1
公开(公告)日：2013-07-16
申请号：US13204522
申请日：2011-08-05
申请人： Robert Mack , Stephen O'Connor
发明人： Robert Mack , Stephen O'Connor
IPC分类号： H04B1/00
CPC分类号： H04B1/707 , H04B2201/709709
摘要： A spread spectrum slip time encoding scheme encodes data values with one or more Pseudo Noise (PN) codes and generates a corresponding PN encoded data stream. Other data values are encoded into the PN encoded data stream by varying a slip time between the 10 encoded data values.
摘要翻译：扩频滑移时间编码方案用一个或多个伪噪声（PN）码对数据值进行编码，并产生相应的PN编码数据流。通过改变10个编码数据值之间的滑移时间，将其它数据值编码到PN编码数据流中。

3. 发明授权

US07893772B1 System and method of loading a programmable counter 有权
标题翻译：加载可编程计数器的系统和方法
公开(公告)号：US07893772B1
公开(公告)日：2011-02-22
申请号：US12327751
申请日：2008-12-03
申请人： Nathan Moyal , David Wright , Stephen O'Connor
发明人： Nathan Moyal , David Wright , Stephen O'Connor
IPC分类号： H03K21/00 , H03K23/00 , H03L7/18
CPC分类号： H03K23/665 , H03K21/406 , H03L7/099 , H03L7/104 , H03L7/183 , H03L2207/06
摘要： A system and method of loading a programmable counter includes storing a first digital divide value in a register. The first digital divide value is then loaded from the register to a programmable counter. The method further includes writing a second digital divide value to the register at a time responsive to a time remaining to complete a counting cycle of the programmable counter.
摘要翻译：加载可编程计数器的系统和方法包括将第一数字除法值存储在寄存器中。然后，第一数字分频值从寄存器加载到可编程计数器。该方法还包括在响应于剩余时间完成可编程计数器的计数周期的时间向寄存器写入第二数字除法值。

4. 发明申请

US20100179125A1 SUBSTITUTED 4-AMINO-PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS 有权
标题翻译：取代的4-氨基吡咯烷酮衍生物有助于治疗与增殖性疾病有关的高血压病和疾病
公开(公告)号：US20100179125A1
公开(公告)日：2010-07-15
申请号：US12552923
申请日：2009-09-02
申请人： Julie A. Dixon , Barton Phillips , Furahi Achebe , Harold C. E. Kluender , Jason Newcom , Kyle Parcella , Steven Magnuson , Zhenqiu Hong , Zhonghua Zhang , Zheng Liu , Uday Khire , Lei Wang , Martin Michels , Brent Chandler , Stephen O'Connor
发明人： Julie A. Dixon , Barton Phillips , Furahi Achebe , Harold C. E. Kluender , Jason Newcom , Kyle Parcella , Steven Magnuson , Zhenqiu Hong , Zhonghua Zhang , Zheng Liu , Uday Khire , Lei Wang , Martin Michels , Brent Chandler , Stephen O'Connor
IPC分类号： A61K31/53 , C07D487/04 , A61K31/5377 , A61K31/541 , A61K31/553 , A61P35/00 , C12N5/00
CPC分类号： C07D487/04
摘要： This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.
摘要翻译：本发明涉及新颖的吡咯并三嗪化合物，含有这些化合物的药物组合物，以及这些化合物或组合物用于治疗高增殖和/或血管生成障碍，作为唯一试剂或与其它活性成分组合的用途。

5. 发明授权

US07696303B2 Polymers their preparation and uses 有权
标题翻译：聚合物的制备和用途
公开(公告)号：US07696303B2
公开(公告)日：2010-04-13
申请号：US10514137
申请日：2003-05-09
申请人： Richard O'Dell , Carl Towns , Brian Tierney , Stephen O'Connor , Ilaria Grizzi , Clare L. Foden , Nalinkumar Patel , Mark L. Leadbeater , Lorraine Murtagh
发明人： Richard O'Dell , Carl Towns , Brian Tierney , Stephen O'Connor , Ilaria Grizzi , Clare L. Foden , Nalinkumar Patel , Mark L. Leadbeater , Lorraine Murtagh
IPC分类号： H01L51/54 , H05B33/14 , C09K11/06 , C08G61/12
CPC分类号： H01L51/0043 , C08G61/02 , C08G61/12 , C08G73/026 , C09K11/06 , C09K2211/1408 , C09K2211/1416 , C09K2211/1425 , C09K2211/1433 , H01L51/0039 , H01L51/0059 , H01L51/5012 , Y10S428/917
摘要： A polymer for use in an optical device comprising a first, optionally substituted, repeat unit of formula and a second, optionally substituted, repeat unit of formula wherein each Ar and Ar′ is the same or different and comprises an optionally substituted aryl or heteroaryl group and optionally a third, optionally substituted, repeat unit in a molar ratio of no greater than 5%, the third repeat unit having a formula —Ar—N(Ar)—Ar— and having a single nitrogen atom in its backbone.
摘要翻译：一种用于光学器件的聚合物，其包含第一，任选取代的式的重复单元和第二，任选取代的重复单元，其中每个Ar和Ar'相同或不同，并且包含任选取代的芳基或杂芳基和任选的第三，任选取代的重复单元，其摩尔比不大于5％，第三重复单元具有式-Ar-N（Ar）-Ar-，并且在其主链中具有单个氮原子。

6. 发明申请

US20090253762A1 PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY 失效
公开(公告)号：US20090253762A1
公开(公告)日：2009-10-08
申请号：US12206721
申请日：2008-09-08
申请人： Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
发明人： Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
IPC分类号： A61K31/428 , C07D277/82 , C07D413/02 , A61K31/416 , A61K31/423 , C07D405/02
CPC分类号： C07D263/58 , C07D235/30 , C07D263/60 , C07D277/42 , C07D277/58 , C07D277/82 , C07D405/12 , C07D413/12 , C07D417/12
摘要： This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.

7. 发明申请

US20090236972A1 PHOSPHORESCENT OLED 有权
标题翻译：磷光OLED
公开(公告)号：US20090236972A1
公开(公告)日：2009-09-24
申请号：US11721321
申请日：2005-12-12
申请人： Carl Towns , Stephen O'Connor , Andrew Bruce Holmes
发明人： Carl Towns , Stephen O'Connor , Andrew Bruce Holmes
IPC分类号： H01J1/63 , B05D5/12 , C09K11/06
CPC分类号： H01L51/0085 , H01L51/0039 , H01L51/0043 , H01L51/5016 , Y02E60/36 , Y10S428/917
摘要： An organic light emitting device having a phase-separated light-emissive layer comprising: a charge transport phase comprising a charge transport material; and an emitting phase, the emitting phase comprising a plurality of discrete emissive domains dispersed in the charge transport phase, each emitting domain comprising a host material and one or more metal complexes for emitting light by phosphorescence; wherein the charge transport material has a T1 energy level lower than the T1 energy level of the metal complexes and the host material has a T1 energy level higher than the T1 energy level of the metal complexes.
摘要翻译：一种具有相分离的发光层的有机发光器件，包括：电荷输送相，其包含电荷输送材料; 和发射相，所述发射相包括分散在所述电荷传输阶段中的多个离散发射畴，每个发射区包括主体材料和一个或多个通过磷光发射光的金属络合物; 其中所述电荷传输材料具有低于所述金属络合物的T1能级的T1能级，并且所述主体材料具有高于所述金属络合物的T1能级的T1能级。

8. 发明授权

US07091228B2 Preparation and use of aryl alkyl acid derivatives for the treatment of obesity 失效
公开(公告)号：US07091228B2
公开(公告)日：2006-08-15
申请号：US10839833
申请日：2004-05-06
申请人： Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
发明人： Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
IPC分类号： A61K31/428 , A61K31/426 , C07D277/82 , C07D277/42
CPC分类号： C07D263/58 , C07D235/30 , C07D263/60 , C07D277/42 , C07D277/58 , C07D277/82 , C07D405/12 , C07D413/12 , C07D417/12
摘要： This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.

9. 发明申请

US20050137920A1 Information technology enterprise manager and product portfolio manager application module 有权
标题翻译：信息技术企业经理和产品组合经理应用模块
公开(公告)号：US20050137920A1
公开(公告)日：2005-06-23
申请号：US10745837
申请日：2003-12-22
申请人： Stephen O'Connor , Thomas Niermann
发明人： Stephen O'Connor , Thomas Niermann
IPC分类号： G06Q10/00 , G06F17/60
CPC分类号： G06Q10/06 , G06Q10/06313
摘要： This document discusses, among other things, an information technology (IT) enterprise manager system. In one example, the system includes data groups organized into IT Services, IT Resources, and IT Consumers data groups. The IT Resources data group may include one or more of an IT Applications data group, an IT Assets data group, an IT Staff Data group, and an IT Vendors data group. The IT Consumers data group may include one or both of a Business Processes data group and an IT Clients data group. Information in one data group may use a link to other information in another data group. In one example, the system provides tools and methods for managing a portfolio IT projects through various phases of their lifecycles, such as during project definition, establishing a business case for the project, project design and implementation, and/or project wrap-up. For example, the system may provide user interface displays and report generation that permit the user to compare different projects, such as using business value, probability of success and/or other factors for performing the comparison.
摘要翻译：本文件除其他外，讨论了信息技术（IT）企业管理系统。在一个示例中，系统包括组织成IT服务，IT资源和IT消费者数据组的数据组。 IT资源数据组可能包括一个或多个IT应用程序数据组，IT资产数据组，IT人员数据组和IT供应商数据组。 IT消费者数据组可以包括业务流程数据组和IT客户端数据组中的一个或两个。一个数据组中的信息可以使用到其他数据组中的其他信息的链接。在一个示例中，系统提供了通过其生命周期的各个阶段来管理投资组合IT项目的工具和方法，例如在项目定义期间，为项目建立业务案例，项目设计和实施以及/或项目总结。例如，系统可以提供允许用户比较不同项目的用户界面显示和报告生成，例如使用业务价值，成功概率和/或用于执行比较的其他因素。

10. 发明申请

US20090105122A1 Selective neuropeptide y2 receptor agonists 审中-公开
标题翻译：选择性神经肽y2受体激动剂
公开(公告)号：US20090105122A1
公开(公告)日：2009-04-23
申请号：US10576674
申请日：2004-11-23
申请人： Kevin Lumb , Lynn Decarr , Philip Coish , Stephen O'Connor
发明人： Kevin Lumb , Lynn Decarr , Philip Coish , Stephen O'Connor
IPC分类号： A61K38/28 , C07K7/08 , C07K7/06 , A61K38/08 , A61K38/10
CPC分类号： C07K16/44 , A61K38/00 , C07K14/57545
摘要： This invention provides peptides that act as selective NPY2 receptor agonists in vitro and are efficacious in vivo to reduce food intake. The invention is a peptide selected from a specific group of derivatized NPY-related peptides, or functional equivalents thereof. The invention is also directed to a method of treating a metabolic disease in a mammal comprising administering a therapeutically effective amount of the peptides to said mammal to reduce food intake and body weight.
摘要翻译：本发明提供了在体外作为选择性NPY2受体激动剂的肽并且在体内有效以减少食物摄取。本发明是选自特定组的衍生化的NPY相关肽或其功能等同物的肽。本发明还涉及一种治疗哺乳动物代谢疾病的方法，包括向所述哺乳动物施用治疗有效量的肽以减少食物摄入和体重。

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