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1. 发明授权

US4590941A Cardiac pacer with improved battery system, output circuitry, and emergency operation 失效
标题翻译：心脏起搏器具有改进的电池系统，输出电路和紧急操作
公开(公告)号：US4590941A
公开(公告)日：1986-05-27
申请号：US542515
申请日：1983-10-17
申请人： Stanley H. Saulson , Edward A. Schroeppel , Peter P. Tarjan
发明人： Stanley H. Saulson , Edward A. Schroeppel , Peter P. Tarjan
IPC分类号： A61N1/37 , A61N1/378 , A61N1/36
CPC分类号： A61N1/378 , A61N1/3708
摘要： A fully implantable programmable cardiac pacer includes two main pacing channels driven by a crystal oscillator circuit. For each channel, amplitude and pulse width are programmed in paired combinations corresponding to monotonically increasing charge density. Selectively combinable constant current sources are shared by each channel. A low battery indicator system samples battery voltage relative to two threshold levels. In magnet rate, if the main battery voltage is above the first threshold, the fixed pacer output will be 70 beats per minute. If the battery voltage is between the first and second threshold levels, the fixed pacer output will be 62.5 beats per minute. An emergency RC oscillator continuously produces an output at 52.5 beats per minute and one millisecond pulse width. The emergency output is switched directly to the output of channel 2 when either the low battery voltage falls below the second threshold or the crystal oscillator frequency changes when tested by a frequency checking circuit using the output of the RC oscillator as a reference clock. An emergency battery is coupled to the main battery via a diode steering circuit which allows the remaining capacity to be combined with that of the emergency battery.
摘要翻译：完全可植入的可编程心脏起搏器包括由晶体振荡器电路驱动的两个主起搏通道。对于每个通道，幅度和脉冲宽度以对应于单调递增电荷密度的配对组合进行编程。可选择组合的恒流源由每个通道共享。低电量指示器系统相对于两个阈值电平对电池电压进行采样。在磁体速率下，如果主电池电压高于第一阈值，则固定起搏器输出将为每分钟70次。如果电池电压在第一和第二阈值水平之间，则固定的分路器输出将为每分钟62.5次。紧急RC振荡器连续产生每分钟52.5次和1毫秒脉冲宽度的输出。当电池电压低于第二阈值时，紧急输出直接切换到通道2的输出，或者通过使用RC振荡器的输出作为参考时钟的频率检查电路进行测试时，晶体振荡器频率发生变化。紧急电池通过二极管转向电路与主电池连接，二极管转向电路允许剩余容量与紧急电池组合。

2. 发明授权

US4437466A Cardiac pacer with improved battery system, output circuitry, and emergency operation 失效
标题翻译：心脏起搏器具有改进的电池系统，输出电路和紧急操作
公开(公告)号：US4437466A
公开(公告)日：1984-03-20
申请号：US239467
申请日：1981-03-02
申请人： Stanley H. Saulson , Edward A. Schroeppel , Peter P. Tarjan
发明人： Stanley H. Saulson , Edward A. Schroeppel , Peter P. Tarjan
IPC分类号： A61N1/37 , A61N1/378 , A61N1/36
CPC分类号： A61N1/378 , A61N1/3708
摘要： A fully implantable programmable cardiac pacer includes two main pacing channels driven by a crystal oscillator circuit. For each channel, amplitude and pulse width are programmed in paired combinations corresponding to monotonically increasing charge density. Selectively combinable constant current sources are shared by each channel. A low battery indicator system samples battery voltage relative to two threshold levels. In magnet rate, if the main battery voltage is above the first threshold, the fixed pacer output will be 70 beats per minute. If the battery voltage is between the first and second threshold levels, the first pacer output will be 62.5 beats per minute. An emergency RC oscillator continuously produces an output at 52.5 beats per minute and one millisecond pulse width. The emergency output is switched directly to the output of channel 2 when either the low battery voltage falls below the second threshold or the crystal oscillator frequency changes when tested by a frequency checking circuit using the output of the RC oscillator as a reference clock. An emergency battery is coupled to the main battery via a diode steering circuit which allows the remaining capacity to be combined with that of the emergency battery.
摘要翻译：完全可植入的可编程心脏起搏器包括由晶体振荡器电路驱动的两个主起搏通道。对于每个通道，幅度和脉冲宽度以对应于单调递增电荷密度的配对组合进行编程。可选择组合的恒流源由每个通道共享。低电量指示器系统相对于两个阈值电平对电池电压进行采样。在磁体速率下，如果主电池电压高于第一阈值，则固定起搏器输出将为每分钟70次。如果电池电压在第一和第二阈值水平之间，则第一个起搏器输出将为每分钟62.5次。紧急RC振荡器连续产生每分钟52.5次和1毫秒脉冲宽度的输出。当电池电压低于第二阈值时，紧急输出直接切换到通道2的输出，或者通过使用RC振荡器的输出作为参考时钟的频率检查电路进行测试时，晶体振荡器频率发生变化。紧急电池通过二极管转向电路与主电池连接，二极管转向电路允许剩余容量与紧急电池组合。

3. 发明授权

US4416282A Cardiac pacer with improved, output circuitry 失效
标题翻译：心脏起搏器具有改进的输出电路
公开(公告)号：US4416282A
公开(公告)日：1983-11-22
申请号：US239468
申请日：1981-03-02
申请人： Stanley H. Saulson , Peter P. Tarjan
发明人： Stanley H. Saulson , Peter P. Tarjan
IPC分类号： A61N1/37 , A61N1/372 , A61N1/36
CPC分类号： A61N1/3708 , A61N1/37211 , A61N1/37258
摘要： A fully implantable programmable cardiac pacer includes two main pacing channels driven by a crystal oscillator circuit. For each channel, amplitude and pulse width are programmed in paired combinations corresponding to monotonically increasing charge density. Selectively combinable constant current sources are shared by each channel. A low battery indicator system samples battery voltage relative to two threshold levels. In magnet rate, if the main battery voltage is above the first threshold, the fixed pacer output will be 70 beats per minute. If the battery voltage is between the first and second threshold levels, the fixed pacer output will be 62.5 beats per minute. An emergency RC oscillator continuously produces an output at 52.5 beats per minute and one millisecond pulse width. The emergency output is switched directly to the output of channel 2 when either the low battery voltage falls below the second threshold or the crystal oscillator frequency changes when tested by a frequency checking circuit using the output of the RC oscillator as a reference clock. An emergency battery is coupled to the main battery via a diode steering circuit which allows the remaining capacity to be combined with that of the emergency battery.
摘要翻译：完全可植入的可编程心脏起搏器包括由晶体振荡器电路驱动的两个主起搏通道。对于每个通道，幅度和脉冲宽度以对应于单调递增电荷密度的配对组合进行编程。可选择组合的恒流源由每个通道共享。低电量指示器系统相对于两个阈值电平对电池电压进行采样。在磁体速率下，如果主电池电压高于第一阈值，则固定起搏器输出将为每分钟70次。如果电池电压在第一和第二阈值水平之间，则固定的分路器输出将为每分钟62.5次。紧急RC振荡器连续产生每分钟52.5次和1毫秒脉冲宽度的输出。当电池电压低于第二阈值时，紧急输出直接切换到通道2的输出，或者通过使用RC振荡器的输出作为参考时钟的频率检查电路进行测试时，晶体振荡器频率发生变化。紧急电池通过二极管转向电路与主电池连接，二极管转向电路允许剩余容量与紧急电池组合。

4. 发明授权

US4608986A Pacing lead with straight wire conductors 失效
标题翻译：用直线导线起搏引线
公开(公告)号：US4608986A
公开(公告)日：1986-09-02
申请号：US656614
申请日：1984-10-01
申请人： William J. Beranek , Stanley H. Saulson
发明人： William J. Beranek , Stanley H. Saulson
IPC分类号： A61N1/05 , A61N1/04
CPC分类号： A61N1/056
摘要： The pacing lead comprises an elongate lead body which is made of pliable insulation material, which has a generally circular cross-section, which has a proximal end and a distal end and which has at least one lumen therein extending substantially the length thereof. At least one distal electrode or sensor is mounted to the lead body at or adjacent the distal end of the lead body. At least one proximal connector is mounted to the lead body at or adjacent the proximal end of the lead body. At least one uninsulated, relaxed, uncoiled wire conductor is loosely and slidably received in the lumen and is made of a material having a high flexibility and bendability such as of a nickel and titanium alloy. The wire conductor has a diameter less than the diameter of the at least one lumen and is connected at each end, respectively, to the distal electrode and the proximal connector.
摘要翻译：起搏引线包括细长的引线主体，其由柔韧的绝缘材料制成，其具有大致圆形的横截面，其具有近端和远端，并且其至少一个内腔基本上延伸长度延伸。至少一个远端电极或传感器在引线主体的远端处或邻近引线主体的远端处安装到引线主体。至少一个近端连接器在引线本体的近端处或邻近引线本体的近端处安装到引线主体。至少一个未绝缘的，松弛的，未开卷的电线导体松动地和可滑动地容纳在内腔中，并且由具有高的柔性和弯曲性的材料制成，例如镍和钛合金。电线导体的直径小于至少一个内腔的直径，并且在每个端部分别连接到远端电极和近端连接器。

5. 发明授权

US4576035A Self-calibrating differential condition sensor 失效
标题翻译：自校准差动传感器
公开(公告)号：US4576035A
公开(公告)日：1986-03-18
申请号：US763891
申请日：1985-08-09
申请人： Michael D. Hooven , Stanley H. Saulson
发明人： Michael D. Hooven , Stanley H. Saulson
IPC分类号： G01L27/00 , G01N27/416
CPC分类号： G01N27/4165 , G01L27/005
摘要： A self calibrating differential pressure sensor having a pair of pressure transducers connected in fluid series with two on/off valves. The system can be calibrated to eliminate base line or zero shift and can also be used to measure other variable conditions, such as differential voltage between two voltage points or differential chemical concentrations between two concentration points.
摘要翻译：一种自校准差压传感器，其具有一对压力传感器，该压力传感器与两个开关阀以流体系列连接。该系统可以进行校准，以消除基线或零点偏移，也可用于测量其他可变条件，例如两个电压点之间的差分电压或两个浓度点之间的差分化学浓度。

6. 发明授权

US4530368A Temporary bipolar pacing lead 失效
标题翻译：临时双极起搏线
公开(公告)号：US4530368A
公开(公告)日：1985-07-23
申请号：US613586
申请日：1984-05-24
申请人： Stanley H. Saulson , Walter H. Wesner
发明人： Stanley H. Saulson , Walter H. Wesner
IPC分类号： A61N1/05 , A61N1/04
CPC分类号： A61N1/0587
摘要： The bipolar temporary pacing lead comprises a lead body having a proximal end portion and a distal end portion and including first and second spaced apart wire conductors each encased in an insulating material to form insulated wire conductors. A curved needle is connected to at least one of the first and second wire conductors in the lead body distal end portion. A straight needle is connected to a first elongate non-conductive member and a second elongate non-conductive member which are connected by means of first and second terminal sleeves to proximal ends of the first and second wire conductors. The distal end portion of the lead body has insulation removed from portions of the respective first and second insulated conductors thereby to form in the lead body distal end portion a first electrode-forming, bare wire conductor portion and a second electrode-forming, bare wire conductor portion.
摘要翻译：双极临时起搏引线包括具有近端部分和远端部分的引线主体，并且包括第一和第二间隔开的导线导体，每个导体导体封装在绝缘材料中以形成绝缘线导体。弯曲的针连接到引线体远端部分中的第一和第二导线的至少一个。直针连接到第一细长非导电构件和第二细长非导电构件，第二细长非导电构件通过第一和第二端子套筒连接到第一和第二导线的近端。引线体的前端部具有从各自的第一绝缘导体和第二绝缘导体的部分去除的绝缘体，从而在引线体前端部形成有第一电极形成用裸线导体部和第二电极形成用裸线导体部分。

7. 发明授权

US4628944A Cardiac pacing lead with biodegradable fixation structure 失效
标题翻译：心脏起搏带有可生物降解的固定结构
公开(公告)号：US4628944A
公开(公告)日：1986-12-16
申请号：US817790
申请日：1986-01-07
申请人： David C. MacGregor , Stanley H. Saulson
发明人： David C. MacGregor , Stanley H. Saulson
IPC分类号： A61N1/05
CPC分类号： A61N1/057
摘要： Disclosed is a cardiac pacing lead comprising an electrical stimulating member (electrode) with a plurality of biodegradable fins adjacent to its tip and with or without a porous metal coating. After surgical introduction, temporary fixation of the device to the surface of the cardiac wall is supplied by the fins. The device achieves permanent fixation by ingrowth of viable tissue into the interstices of the porous electrode and/or by tissue ensheathment of the distal portion of the lead. The process of permanent fixation occurs over a period of weeks during which time the fins are gradually absorbed into the blood and/or adjacent tissue. The lead can also be used to stimulate tissue other than cardiac tissue, such as nervous system tissue.
摘要翻译：公开了一种心脏起搏引线，其包括电刺激构件（电极），其具有与其尖端相邻的多个可生物降解的翅片，并且具有或不具有多孔金属涂层。在手术引入之后，通过鳍片提供装置临时固定到心脏壁的表面。该装置通过活组织的向内生长进入多孔电极的间隙和/或通过导线的远端部分的组织接触而实现永久固定。永久固定的过程发生在几周的时间段内，翅片逐渐被血液和/或邻近的组织吸收。铅也可用于刺激心脏组织以外的组织，例如神经系统组织。

8. 发明授权

US4450842A Solid state reference electrode 失效
标题翻译：固态参考电极
公开(公告)号：US4450842A
公开(公告)日：1984-05-29
申请号：US318693
申请日：1981-11-06
申请人： Gregory L. Zick , Stanley H. Saulson
发明人： Gregory L. Zick , Stanley H. Saulson
IPC分类号： G01N27/30 , G01N27/48 , A61B5/00
CPC分类号： G01N27/301 , G01N33/4925
摘要： In the reference electrode construction disclosed herein, silver and silver chloride particles are incorporated in a mixture including a fusible glass frit. After being printed on a suitable substrate, the mixture is fired to bond the silver/silver chloride composite into a conductive film on the surface of the substrate.
摘要翻译：在本文公开的参考电极结构中，将银和氯化银颗粒引入包含可熔玻璃料的混合物中。在合适的基材上印刷之后，将该混合物烧结以将银/氯化银复合物粘合到基材表面上的导电膜中。

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