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1. 发明申请

WO2008017685A1 NITRATE ESTERS OF PIPERIDINES 审中-公开
标题翻译：硝酸酯系列
公开(公告)号：WO2008017685A1
公开(公告)日：2008-02-14
申请号：PCT/EP2007/058207
申请日：2007-08-07
申请人： Speedel Experimenta AG , HEROLD, Peter , MAH, Robert , STUTZ, Stefan , TSCHINKE, Vincenzo , LYOTHIER, Isabelle , SCHUMACHER, Christoph , MARTI, Christiane , JOTTERAND, Nathalie
发明人： HEROLD, Peter , MAH, Robert , STUTZ, Stefan , TSCHINKE, Vincenzo , LYOTHIER, Isabelle , SCHUMACHER, Christoph , MARTI, Christiane , JOTTERAND, Nathalie
IPC分类号： C07D401/04 , C07D405/04 , C07D405/12 , C07D413/04 , A61K31/445 , A61P9/00
CPC分类号： C07D413/04 , C07D211/52 , C07D401/04 , C07D405/04 , C07D405/12
摘要： The application relates to novel nitrate ester derivatives of substituted piperidines of the general formula (I), wherein R 1 , R 2 , R 3 , X, Y and Z 0 , and m, n, p and q have the meanings explained in more detail in the description, a process for their preparation and the use of these compounds as a curative agent in cardiovascular diseases, in particular in high blood pressure and vascular and organ damage accompanying high blood pressure.
摘要翻译：本申请涉及通式（I）的取代哌啶的新型硝酸酯衍生物，其中R 1，R 2，R 3， X，Y和Z 0，m，n，p和q具有在说明书中更详细解释的含义，其制备方法和这些化合物作为心血管中的治疗剂的用途疾病，特别是伴有高血压的高血压和血管和器官损伤。

2. 发明申请

WO2009053452A1 4,4-DISUBSTITUTED PIPERIDINES 审中-公开
标题翻译： 4,4-取代的哌啶
公开(公告)号：WO2009053452A1
公开(公告)日：2009-04-30
申请号：PCT/EP2008/064417
申请日：2008-10-24
申请人： SPEEDEL EXPERIMENTA AG , HEROLD, Peter , MAH, Robert , TSCHINKE, Vincenzo , BEHNKE, Dirk , JELAKOVIC, Stjepan , JOTTERAND, Nathalie , STUTZ, Stefan , LYOTHIER, Isabelle
发明人： HEROLD, Peter , MAH, Robert , TSCHINKE, Vincenzo , BEHNKE, Dirk , JELAKOVIC, Stjepan , JOTTERAND, Nathalie , STUTZ, Stefan , LYOTHIER, Isabelle
IPC分类号： C07D413/14 , C07D413/12 , A61K31/538 , A61P9/12
CPC分类号： C07D413/12 , C07D413/14
摘要： The application relates to 4,4-disubstituted piperidines of the general formula (I) and their salts, preferably their pharmaceutically acceptable salts, in which R 2 , has the meanings explained in the description, a process for their preparation and the use of these compounds as medicines, especially as renin inhibitors.
摘要翻译：本申请涉及通式（I）的4,4-二取代哌啶及其盐，优选其药学上可接受的盐，其中R2具有说明书中所述的含义，其制备方法和这些化合物的用途作为药物，特别是作为肾素抑制剂。

3. 发明申请

WO2007141318A1 2,5-DISUBSTITUTED PIPERIDINES 审中-公开
标题翻译： 2,5-取代的哌啶
公开(公告)号：WO2007141318A1
公开(公告)日：2007-12-13
申请号：PCT/EP2007/055627
申请日：2007-06-07
申请人： SPEEDEL EXPERIMENTA AG , HEROLD, Peter , MAH, Robert , STUTZ, Stefan , TSCHINKE, Vincenzo , LYOTHIER, Isabelle , JELAKOVIC, Stjepan , QUIRMBACH, Michael , MARTI, Christiane
发明人： HEROLD, Peter , MAH, Robert , STUTZ, Stefan , TSCHINKE, Vincenzo , LYOTHIER, Isabelle , JELAKOVIC, Stjepan , QUIRMBACH, Michael , MARTI, Christiane
IPC分类号： C07D405/12 , C07D405/14 , C07D413/12 , C07D413/14 , A61K31/538 , A61P9/12
CPC分类号： C07D413/12 , C07D405/12 , C07D405/14 , C07D413/14
摘要： The application relates to 2,5-disubstituted piperidines, their preparation and use as medicines, especially as renin inhibitors, of the general formula (I) in which R, R 1 and X are each as defined in detail in the description, and pharmaceutical preparations comprising these compounds.
摘要翻译：本申请涉及2,5-二取代哌啶，其制备和用作药物，特别是作为通式（I）的肾素抑制剂，其中R 1，R 1和X 2各自如描述中的细节，以及包含这些化合物的药物制剂。

4. 发明申请

WO2007085651A1 PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS 审中-公开
标题翻译：制备有机化合物的方法
公开(公告)号：WO2007085651A1
公开(公告)日：2007-08-02
申请号：PCT/EP2007/050816
申请日：2007-01-29
申请人： Speedel Experimenta AG , HEROLD, Peter , STUTZ, Stefan , MAH, Robert , STOJANOVIC, Aleksandar , LYOTHIER, Isabelle , BEHNKE, Dirk , SPINDLER, Felix , BAPPERT, Erhard
发明人： HEROLD, Peter , STUTZ, Stefan , MAH, Robert , STOJANOVIC, Aleksandar , LYOTHIER, Isabelle , BEHNKE, Dirk , SPINDLER, Felix , BAPPERT, Erhard
IPC分类号： C07D231/56 , C07D471/04
CPC分类号： C07D471/04 , C07D231/56
摘要： Compounds of the formula I, in which R' 1 and R' 2 represent, independently of one another, H, C 1 -C 8 -alkyl, halogen, polyhalo-C 1 -C 8 -alkoxy, polyhalo-C 1 -C 8 -alkyl, C 1 -C 8 -alkoxy, C 1 -C 8 -alkoxy-C 1 -C 8 -alkyl or C 1 -C 8 -alkoxy-C 1 -C 8 -alkoxy, R' 1 and R' 2 not simultaneously representing H, and R' 3 represents C 1 -C 8 -alkyl and in which the carbon atom to which the R' 3 radical is bonded exhibits either the (R) or (S) configuration, the (R) configuration being preferred, can be obtained in high yields by a stereoselective addition of R' 3 -substituted propionates to RV and R' 2 -substituted unsaturated bicyclic heterocyclyl aldehydes of the formula R-CHO to give corresponding 3-R-3-hydroxy-2-R' 3 -propionates. Conversion of the OH group to a leaving group, subsequently a regioselective elimination to give 3-R-2-R' 3 -propenoates, followed by 1 ) the saponification to give the corresponding 3-R-2-R' 3 -propenoic acids, the enantioselective hydrogenation thereof to give corresponding chiral 3-R-2-R' 3 -propanoic acids and the reduction thereof, or 2) the saponification to give the corresponding 3-R-2-R' 3 -propenoic acids, the reduction thereof to give corresponding 3-R-2-R' 3 -allyl alcohols and the enantioselective hydrogenation thereof, or 3) the reduction to give corresponding 3-R-2-R' 3 -allyl alcohols and the enantioselective hydrogenation thereof, R being
摘要翻译：其中R 1'和R“2'的式I化合物彼此独立地表示H，C 1 -C 3烷基，烷基，卤素，多卤代-C 1 -C 8 - 烷氧基，多卤代-C 1 -C 1 - C 1 -C 8 - 烷氧基，C 1 -C 8 - 烷基，C 1 -C 8 - 烷氧基，C 1 -C 8 - - 烷氧基-C 1 -C 8 - 烷基或C 1 -C 8 - 烷氧基-C R 1'和R“2不同时表示H，R' N 3表示C 1 -C 8 - 烷基，并且其中R'3个基团的碳原子是（R）或（S）构型可以以高收率通过立体选择性添加R'3 - 取代丙酸酯至RV和R' 式R-CHO的2-取代的不饱和双环杂环基醛，得到相应的3-R-3-羟基-2R'3 - 丙酸酯。将OH基转化为离去基团，随后进行区域选择性消除，得到3-R-2-R“3 - 丙烯酸酯，然后1）皂化，得到相应的3-R-2 -R'3'-丙烯酸，其对映选择性氢化反应，得到相应的手性3-R-2-R'3'-丙酸及其还原剂，或2）皂化，得到相应的3-R-2-R“3 - 丙烯酸，将其还原，得到相应的3-R-2-R”3 - 烯丙基醇和其对映体选择性氢化，或3）还原反应得到相应的3-R-2-R“3 - 烯丙醇及其对映选择性氢化，R为

5. 发明申请

WO2008055941A1 PROCESS FOR PREPARING OF 2-ALKYL 3-ARYL PROP-2-2ENE-1-OLS 审中-公开
标题翻译：制备2-烷基-3-芳基丙-2-烯-1-醇的方法
公开(公告)号：WO2008055941A1
公开(公告)日：2008-05-15
申请号：PCT/EP2007/062024
申请日：2007-11-08
申请人： SPEEDEL EXPERIMENTA AG , HEROLD, Peter , MAH, Robert , STUTZ, Stefan , STOJANOVIC, Aleksandar , LYOTHIER, Isabelle , BEHNKE, Dirk
发明人： HEROLD, Peter , MAH, Robert , STUTZ, Stefan , STOJANOVIC, Aleksandar , LYOTHIER, Isabelle , BEHNKE, Dirk
IPC分类号： C07C29/36 , C07C29/44 , C07C41/18 , C07C41/30 , C07C43/23
CPC分类号： C07C41/20 , C07B2200/07 , C07C41/22 , C07C41/30 , C07C231/12 , C07C235/34 , C07C43/23 , C07C43/225
摘要： Process for preparing a compound of the formula (I) in which R 1 and R 2 are each independently H, C 1 -C 8 -alkyl, halogen, polyhalo-C 1 -C 8 -alkoxy, polyhalo-C 1 -C 8 -alkyl, C 1 -C 8 -alkoxy, C 1 -C 8 -alkoxy-C 1 -C 8 -alkyl, or C 1 -C 8 -alkoxy-C 1 -C 8 -alkoxy, where R 1 and R 2 are not both H, and R 3 is C 1 -C 8 -alkyl, which is characterized in that a) a compound of the formula (II) in which R 1 and R 2 are each as defined above and X is Br, I, triflate, toyslate or mesylate is reacted with prop-2-yn-1-ol to give the compound of the formula (III), b) the compound of the formula (III) is reacted with an alkyl-metal compound in which "alkyl" is as defined above for R 3 to give a compound of the formula (I).
摘要翻译：制备式（I）化合物的方法，其中R 1和R 2各自独立地为H，C 1 -C 3 烷基，卤素，多卤代-C 1 -C 8 - 烷氧基，多卤代-C 1 -C 3 C 1 -C 8烷基，C 1 -C 8 - 烷氧基，C 1 -C 8 - 烷基，C 1 -C 8 - 烷氧基，C 1 -C 8 - - 烷氧基-C 1 -C 8 - 烷基或C 1 -C 8 - 烷氧基-C 其中R 1和R 2都不是H，R 1和R 2都不是H， 3是C 1 -C 8 - 烷基，其特征在于a）式（II）的化合物，其中R 1 R 2和R 2各自如上所定义，X是Br，I，三氟甲磺酸酯，玩具和甲磺酸酯与丙-2-炔-1-醇反应，得到式（III）的化合物，b）式（III）化合物与烷基金属化合物反应，其中“烷基”如上述R 3所定义，得到式（I ）。

6. 发明申请

WO2008113835A1 PROCESS FOR PREPARING (R OR S)-5-{1-AZIDO-3-[6-METHOXY-5-(3-METHOXY-PROPOXY)-PYRIDIN-3-YLMETHYL]-4-METHYL-PENTYL}-3-ALKYL-DIHYDRO-FURAN-2-ONE 审中-公开
标题翻译：（R OR S）-5- {1-氨基-3- [6-甲氧基-5-（3-甲氧基 - 丙氧基） - 吡啶-3-基]甲基] -4-甲基戊-3-炔酸的方法 - 二氢 - 呋喃-2-酮
公开(公告)号：WO2008113835A1
公开(公告)日：2008-09-25
申请号：PCT/EP2008/053323
申请日：2008-03-19
申请人： SPEEDEL EXPERIMENTA AG , HEROLD, Peter , MAH, Robert , STUTZ, Stefan , STOJANOVIC, Aleksandar , LYOTHIER, Isabelle , BEHNKE, Dirk
发明人： HEROLD, Peter , MAH, Robert , STUTZ, Stefan , STOJANOVIC, Aleksandar , LYOTHIER, Isabelle , BEHNKE, Dirk
IPC分类号： C07D213/69
CPC分类号： C07D213/69 , C07D405/06
摘要： Compounds of the formula (E), in which R' 3 is isopropyl and R' 4 is C 1 -C 8 -alkyl, and in which the carbon atom to which the R' 3 radical is bonded has either (R) or (S) configuration, preference being given to (R) configuration, are obtainable in high yields A) by a stereoselective addition of isopropyl-substitutedpropionic esters to 6- methoxy-5-(3-methoxypropoxy)pyridine-3-carbaldehyde to give corresponding 2- {hydroxy-[6-methoxy-5-(3-methoxypropoxy)pyridin-3-yl]methyl}-3-methylbutanoic esters, subsequent conversion of the OH group to a leaving group, and a subsequent regioselective elimination to give 2-[1-[6-methoxy-5-(3-methoxypropoxy)pyridin-3-yl]- meth-(E)-ylidene]-3-methylbutanoic esters, followed by 1) hydrolysis to give the corresponding 2-[1-[6-methoxy-5-(3-methoxypropoxy)- pyridin-3-yl]meth-(E)-ylidene]-3-methylbutanoic acid, the enantioselective hydrogenation thereof to the corresponding chiral 2-[6-methoxy-5-(3-methoxy- propoxy)pyridin-3-ylmethyl]-3-methylbutanoic acid and the reduction thereof,or 2) hydrolysis to the corresponding 2-[1-[6-methoxy-5-(3-methoxypropoxy)pyridin-3- yl]meth-(E)-ylidene]-3-methylbutanoic acid, the reduction thereof to the corresponding 2-[1-[6-methoxy-5-(3-methoxypropoxy)pyridin-3-yl]meth-(E)-ylidene]-3- methylbutan-1-ol and the enantioselective hydrogenation thereof, or 3) reduction to the corresponding 2-[1-[6-methoxy-5-(3-methoxypropoxy)pyridin-3-yl]- meth-(E)-ylidene]-3-methylbutan-1-ol and the enantioselective hydrogenation thereof, or B) by a Sonogashira coupling of 5-bromo-2-methoxy-3-(3-methoxypropoxy)pyridine, SP-P2216_ATE -80- 5-iodo-2-methoxy-3-(3-methoxypropoxy)pyridine or of trifluoromethanesulphonic acid 6-methoxy-5-(3-methoxypropoxy)pyridin-3-yl ester with 2-propyn-1-ol to give 3-[6- methoxy-5-(3-methoxypropoxy)pyridin-3-yl]prop-2-yn-1-ol, followed by addition of an R' 3 -Grignard compound to give 2-[1-[6-methoxy-5-(3-methoxypropoxy)pyridin-3-yl]- meth-(E)-ylidene]-3-methylbutan-1-ol and the enantioselective hydrogenation thereof; substitution of the chiral 2-[6-methoxy-5-(3-methoxy-propoxy)-pyridin-3-ylmethyl]-3- methyl-butan-1-ol resulting from pathways A) or B)to give 5-(2-halomethyl-3-methyl- butyl)-2-methoxy-3-(3-methoxy-propoxy)-pyridine, coupling thereof with a (E)-(R)-5- halo-2-alkyl-pent-4-enoic acid amide, followed by halogenation,hydroxylation lactonizatization and azidation.
摘要翻译：式（E）的化合物，其中R'3是异丙基，R'4是C 1 -C 8烷基，（R）或（S）构型，其中R'3'基团所连接的碳原子具有（R）或（S）构型，优选为（R）构型）（3-甲氧基丙氧基）吡啶-3-甲醛立体选择性加成异丙基取代的丙酸酯得到相应的2- {羟基 - [6-甲氧基-5-（3-甲氧基丙氧基））吡啶-3-基]甲基} -3-甲基丁酸酯，随后将OH基转化为离去基团，随后进行区域选择性消除，得到2- [1- [6-甲氧基-5-（3-甲氧基丙氧基）吡啶-3-基] - 甲基 - （E） - 亚基] -3-甲基丁酸酯，然后1）水解，得到相应的2- [1- [6-甲氧基-5-（3-甲氧基丙氧基）吡啶-3-基]甲基 - （E） - 亚基] -3-甲基丁酸，其对映选择性氢化为相应的手性2- [6-甲氧基-5-（3-甲氧基 - 丙氧基）吡啶-3-基甲基] -3-甲基丁酸及其还原，或2）水解成相应的2- [1- [6-甲氧基-5-（3-甲氧基丙氧基）吡啶-3-基]甲基 - （E） - 亚基] -3-甲基丁酸，将其还原为相应的2- [1- [6-甲氧基-5-（3-甲氧基丙氧基）吡啶-3-基]甲基 - （E） - 亚基] 3-甲基丁-1-醇及其对映选择性氢化，或3）还原成相应的2- [1- [6-甲氧基-5-（3-甲氧基丙氧基）吡啶-3-基] - 甲基 - （E） - 亚基] -3-甲基丁-1-醇及其对映选择性氢化，或B）通过5-溴-2-甲氧基-3-（3-甲氧基丙氧基）吡啶的Sonogashira偶联，SP-P2216_ATE -80- -2-甲氧基-3-（3-甲氧基丙氧基）吡啶或三氟甲磺酸6-甲氧基-5-（3-甲氧基丙氧基）吡啶-3-基酯与2-丙炔-1-醇的混合物，得到3- [6-甲氧基 -5-（3-甲氧基丙氧基）吡啶-3-基]丙-2-炔-1-醇，然后加入R''3 - 标准化合物，得到2- [1- [ 6-甲氧基-5-（3-甲氧基丙氧基）吡啶-3-基] - m （E） - 亚基] -3-甲基丁-1-醇及其对映选择性氢化; 取代由途径A）或B）得到的手性2- [6-甲氧基-5-（3-甲氧基 - 丙氧基） - 吡啶-3-基甲基] -3-甲基 - 丁-1-醇，得到5-（ -2-甲氧基-3-（3-甲氧基 - 丙氧基） - 吡啶，与（E） - （R）-5-卤代-2-烷基 - 戊-4 - 烯酸酰胺，然后卤化，羟基化内酯化和叠氮化。

7. 发明申请

WO2008055939A2 PROCESS FOR PREPARING ORGANIC COMPOUNDS 审中-公开
标题翻译：制备有机化合物的方法
公开(公告)号：WO2008055939A2
公开(公告)日：2008-05-15
申请号：PCT/EP2007/062022
申请日：2007-11-08
申请人： Speedel Experimenta AG , HEROLD, Peter , MAH, Robert , STUTZ, Stefan , STOJANOVIC, Aleksandar , LYOTHIER, Isabelle , BEHNKE, Dirk
发明人： HEROLD, Peter , MAH, Robert , STUTZ, Stefan , STOJANOVIC, Aleksandar , LYOTHIER, Isabelle , BEHNKE, Dirk
IPC分类号： C07D231/56
CPC分类号： C07D231/56
摘要： Process for preparing a compound of the formula (I) in which Het is a bicyclic unsaturated heterocyclyl bonded to the rest of the molecule via a carbon atom, where the ring not bonded directly to the rest of the molecule is substituted by R 1 and R 2 , R 1 and R 2 are each independently H, C 1 -C 8 -alkyl, halogen, polyhalo-C 1 -C 8 -alkoxy, polyhalo-C 1 -C 8 -alkyl, C 1 -C 8 -alkoxy, C 1 -C 8 -alkoxy-C 1 -C 8 -alkyl, or C 1 -C 8 -alkoxy-C 1 -C 8 -alkoxy, where R 1 and R 2 are not both H, and R 3 is C 1 -C 8 -alkyl, which is characterized in that a) a compound of the formula ( II) in which Het, R 1 and R 2 are each as defined above and X is Br, I, triflate, tosylate or mesylate is reacted with prop-2-yn-1-ol to give a compound of the formula (III) and b) the compound of the formula (III) is reacted with an alkyl-metal compound in which "alkyl" is as defined above for R 3 to give a compound of the formula (I).
摘要翻译：制备其中Het是通过碳原子与分子的其余部分键合的双环不饱和杂环基的式（I）化合物的方法，其中不与分子的其余部分键合的环被R 1和R 2，R 1和R 2各自独立地为H，C 1〜 C 8 - 烷基，卤素，多卤代-C 1 -C 8 - 烷氧基，多卤代-C 1 - C 1 -C 8 - 烷基，C 1 -C 8 - 烷氧基，C 1 -C 8 - 烷基，C 1 -C 8 - 烷氧基-C 1 -C 8 - 烷基或C 1 -C 8 - 烷氧基 -C 1 -C 8 - 烷氧基，其中R 1和R 2不都是H，R 其特征在于a）式（II）化合物，其中Het，C 1 -C 6烷基，C 1 -C 6烷基， R 1和R 2各自如上所定义，X是Br，I，三氟甲磺酸酯，甲苯磺酸酯或甲磺酸酯与丙-2-炔-1-醇反应，得到一种化合物（III）和b）使式（III）的化合物与烷基金属化合物反应，其中“烷基”如上述R 3所定义，得到式（一世）。

8. 发明申请

WO2009106599A2 SUBSTITUTED PIPERIDINES AS THERAPEUTIC COMPOUNDS 审中-公开
标题翻译：用取代的哌啶作为治疗化合物
公开(公告)号：WO2009106599A2
公开(公告)日：2009-09-03
申请号：PCT/EP2009/052335
申请日：2009-02-27
申请人： NOVARTIS AG , HEROLD, Peter , MAH, Robert , STUTZ, Stefan , TSCHINKE, Vincenzo , LYOTHIER, Isabelle , JELAKOVIC, Stjepan
发明人： HEROLD, Peter , MAH, Robert , STUTZ, Stefan , TSCHINKE, Vincenzo , LYOTHIER, Isabelle , JELAKOVIC, Stjepan
IPC分类号： C07D405/12 , C07D405/14 , C07D413/12 , C07D413/14 , A61K31/445 , A61K31/4523 , A61K31/538 , A61K31/5386
CPC分类号： C07D405/12 , C07D405/14 , C07D413/12 , C07D413/14
摘要： Use of compounds of the general formula (I) and pharmaceutically acceptable salt thereof, in which R, R 1 and X have the definitions illustrated in detail in the description, as beta-secretase, cathepsin D, plasmepsin Il and/or HIV protease inhibitors.
摘要翻译：通式（I）的化合物及其药学上可接受的盐的用途，其中R 1，R 2和X具有在说明书中详细说明的定义，作为 β-分泌酶，组织蛋白酶D，plasmepsin II和/或HIV蛋白酶抑制剂。

9. 发明公开

EP2044059A1 2,5-DISUBSTITUTED PIPERIDINES 审中-公开
标题翻译： 2,5-DISUBSTITUIERTE PIPERIDINE
公开(公告)号：EP2044059A1
公开(公告)日：2009-04-08
申请号：EP07729989.9
申请日：2007-06-07
申请人： Speedel Experimenta AG
发明人： HEROLD, Peter , MAH, Robert , STUTZ, Stefan , TSCHINKE, Vincenzo , LYOTHIER, Isabelle , JELAKOVIC, Stjepan , QUIRMBACH, Michael , MARTI, Christiane
IPC分类号： C07D405/12 , C07D405/14 , C07D413/12 , C07D413/14 , A61K31/538 , A61P9/12
CPC分类号： C07D413/12 , C07D405/12 , C07D405/14 , C07D413/14
摘要： The application relates to 2,5-disubstituted piperidines, their preparation and use as medicines, especially as renin inhibitors, of the general formula (I) in which R, R1 and X are each as defined in detail in the description, and pharmaceutical preparations comprising these compounds.

10. 发明公开

EP1979323A1 PROCESS FOR THE STEREOSELECTIVE PREPARATION OF ALCOHOLS FROM ALPHA, BETA-INSATURATED COMPOUNDS 审中-公开
标题翻译：一种从ALPHA醇的立体选择性制备，β-不饱和化合物
公开(公告)号：EP1979323A1
公开(公告)日：2008-10-15
申请号：EP07726240.0
申请日：2007-01-29
申请人： Speedel Experimenta AG
发明人： HEROLD, Peter , STUTZ, Stefan , MAH, Robert , STOJANOVIC, Aleksandar , LYOTHIER, Isabelle , BEHNKE, Dirk , SPINDLER, Felix , BAPPERT, Erhard
IPC分类号： C07D231/56 , C07D471/04
CPC分类号： C07D471/04 , C07D231/56
摘要： A process for the synthesis of an alcohol of formula (I), using as intermediate a compound of formula (V).

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