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1. 发明授权

US4557600A Process and device for the control and mixing of a fluid current subjected to centrifugal force 失效
标题翻译：用于控制和混合受到离心力的流体流的过程和装置
公开(公告)号：US4557600A
公开(公告)日：1985-12-10
申请号：US413011
申请日：1982-08-30
申请人： Sigmar Klose , Manfred Pasch , Wolfgang Kleemann , Friedhelm Vieth , Herbert Buschek
发明人： Sigmar Klose , Manfred Pasch , Wolfgang Kleemann , Friedhelm Vieth , Herbert Buschek
IPC分类号： G01N35/00 , B04B5/04 , G01N21/07 , G01N37/00 , G01N1/10
CPC分类号： B04B5/0407 , G01N21/07 , G01N2035/00495 , Y10T436/111666
摘要： A process and a device for the centrifugal control and mixing of a limited volumes of fluid, especially in the rotor of a centrifugal analyzer, has at least one baffle chamber, in a flow canal for the fluid the volume of which is greater than the volume of fluid. It is so shaped that, when the device is rotated at a sufficiently high first speed of rotation, the fluid remains in it. An outlet canal is connected to the baffle chamber the fluid. At least a part thereof lies closer to the axis of rotation than the fluid surface during the rotation with the first speed of rotation. The walls of the outlet canal consist of a material which is wettable by the fluid and, in combination therewith, have cross-section which forces the fluid out of the baffle chamber; by boundary surface force when the device is rotated at a second, slower speed.
摘要翻译：用于离心控制和混合有限体积的流体的方法和装置，特别是在离心分析器的转子中具有至少一个挡板室，用于用于流体的流道中，该流体的体积大于体积的流体。它是如此的形状，使得当装置以足够高的第一旋转速度旋转时，流体保留在其中。出口管连接到挡板室的流体。至少其一部分在与第一旋转速度旋转期间比流体表面更靠近旋转轴线。出口管的壁由可被流体润湿的材料组成，并且与其组合具有迫使流体离开挡板的横截面; 当装置以第二，较慢的速度旋转时，通过边界表面力。

2. 发明授权

US4690899A Process and device for carrying out analytical determinations 失效
标题翻译：用于进行分析测定的过程和设备
公开(公告)号：US4690899A
公开(公告)日：1987-09-01
申请号：US751368
申请日：1985-07-02
申请人： Sigmar Klose , Manfred Pasch , Helmut Schlumberger , Wolfgang Kleemann , Friedhelm Vieth
发明人： Sigmar Klose , Manfred Pasch , Helmut Schlumberger , Wolfgang Kleemann , Friedhelm Vieth
IPC分类号： G01N33/48 , G01N21/07 , G01N33/543 , G01N33/563 , G01N33/68 , G01N21/11
CPC分类号： G01N21/07 , G01N33/54366 , G01N33/563 , G01N33/6857 , Y10T436/111666
摘要： In a process for carrying out an analytical determination by mixing and incubating a sample liquid with at least one dry reagent which is soluble therein to form a reaction mixture liquid and measuring a parameter in the reaction mixture liquid, the sample liquid is first transported along a transport path to the soluble dry reagent and the resulting reaction mixture liquid then further transported along the transport path. The further transporting of the reaction mixture liquid along the transport path is under the influence of a force-change cycle in which centrifugal force and a further force alternately predominate to determine the direction of the further transporting along the transport path. At least one further liquid is transported on another path, part of which is separate from and part of which is common with the transport path, by the force-change cycle in such a manner that at least two of the liquids pass through the common part of the transport path chronologically separated.
摘要翻译：在通过将样品液体与可溶于其中的至少一种干试剂混合并孵育以形成反应混合物液体并测量反应混合物液体中的参数的方法进行分析测定的过程中，首先将样品液体沿着向可溶性干试剂的输送路径和所得到的反应混合物液体进一步沿输送路径输送。反应混合物液体沿着输送路径的进一步输送受力变化循环的影响，其中离心力和进一步的力交替占主导地位，以确定沿输送路径进一步输送的方向。至少一个另外的液体在另一个路径上被传送，其中一部分液体通过力 - 变化循环分开并且其一部分与输送路径共同，使得至少两个液体通过公共部分的运输路径按时间顺序分隔。

3. 发明授权

US4915911A Device for rinsing out a substance present in a zone 失效
标题翻译：用于冲洗区域中存在的物质的装置
公开(公告)号：US4915911A
公开(公告)日：1990-04-10
申请号：US98780
申请日：1987-09-21
申请人： Sigmar Klose , Manfred Pasch , Helmut Schlumberger , Wolfgang Kleeman , Friedhelm Vieth
发明人： Sigmar Klose , Manfred Pasch , Helmut Schlumberger , Wolfgang Kleeman , Friedhelm Vieth
IPC分类号： G01N33/48 , B01J4/00 , B01L3/00 , G01N21/07 , G01N33/543 , G01N35/00
CPC分类号： G01N21/07 , B01L3/5027
摘要： The present invention provides a device for rinsing out a substance present in a zone (d) with a liquid rinsing agent in several rinsing steps and for transferring the rinsing agent emerging from the zone (d) in the last rinsing step to a cuvette (K), wherein the zone (d) is present on a rotor (R) of variable speed of rotation, radially inwardly of the zone (d) on the rotor (R) there is provided a pump chamber (PK) for the rinsing agent which is connected with the zone (d) via a valve chamber (VK2) which fills, under the action of centrifugal force, above a predetermined speed of rotation, from the pump chamber (PK) and empties below the predetermined speed of rotation into the zone (d) and the zone (d) is connected with the cuvette (K) via a pipe (4) which, in one section, the axis of which has a component directed radially outwardly, is directed into a waste chamber (AK).
摘要翻译：本发明提供了一种用于在几个漂洗步骤中用液体漂洗剂冲洗出区域（d）中存在的物质的装置，并用于将在最后一个漂洗步骤中从（d）区域出来的漂洗剂转移到比色皿），其中所述区域（d）存在于所述转子（R）上的所述区域（d）的径向向内的可变速度转子（R）上，其中设置有用于所述漂洗剂的泵室（PK），所述泵室通过阀室（VK2）与区域（d）连接，阀室（VK2）在离心力的作用下从泵室（PK）溢出超过预定转速，并且在预定转速下排空到区域（d）和区域（d）经由管道（4）与试管（K）连接，管道（4）在其一个部分中具有径向向外指向的部件被引导到废物室（AK）中。

4. 发明授权

US09156012B2 Method and device for mixing samples on a support 有权
标题翻译：在支架上混合样品的方法和装置
公开(公告)号：US09156012B2
公开(公告)日：2015-10-13
申请号：US12015000
申请日：2008-01-16
申请人： Karl-Heinz Mann , Thomas Mayer , Friedhelm Vieth
发明人： Karl-Heinz Mann , Thomas Mayer , Friedhelm Vieth
IPC分类号： B01F13/02 , B01F13/00 , B01L3/00 , G01N35/00
CPC分类号： B01F13/0272 , B01F13/0059 , B01F2215/0037 , B01J2219/00493 , B01J2219/00511 , B01J2219/00605 , B01L3/508 , G01N2035/00544 , Y10T436/25
摘要： A method for detecting analytes in a liquid is provided in which the liquid is subjected to a mixing treatment on an area of a support which has in particular immobilized reactants, wherein in the mixing treatment the liquid is impinged upon by a stream of gas that sweeps across at least some areas of the support surface in a scanning manner by means of a jet directed towards the support surface. The invention also concerns a method for mixing a liquid sample comprising an analyte and a device for carrying out the method.
摘要翻译：提供了一种用于检测液体中分析物的方法，其中对特别是固定化反应物的载体的区域进行混合处理，其中在混合处理中，液体被扫过的气流冲击通过朝向支撑表面的射流以扫描方式跨过支撑表面的至少一些区域。本发明还涉及用于混合包含分析物的液体样品和用于实施该方法的装置的方法。

5. 发明申请

US20060019243A1 Method and device for mixing samples on a support 审中-公开
公开(公告)号：US20060019243A1
公开(公告)日：2006-01-26
申请号：US11146343
申请日：2005-06-06
申请人： Karl-Heinz Mann , Thomas Mayer , Friedhelm Vieth
发明人： Karl-Heinz Mann , Thomas Mayer , Friedhelm Vieth
IPC分类号： C12Q1/70 , C12M1/34 , G01N33/551
CPC分类号： B01F13/0272 , B01F13/0059 , B01F2215/0037 , B01J2219/00493 , B01J2219/00511 , B01J2219/00605 , B01L3/508 , G01N2035/00544 , Y10T436/25
摘要： A method for detecting analytes in a liquid is provided in which the liquid is subjected to a mixing treatment on an area of a support which has in particular immobilized reactants, wherein in the mixing treatment the liquid is impinged upon by a stream of gas that sweeps across at least some areas of the support surface in a scanning manner by means of a jet directed towards the support surface. The invention also concerns a method for mixing a liquid sample comprising an analyte and a device for carrying out the method.

6. 发明申请

US20080113450A1 METHOD AND DEVICE FOR MIXING SAMPLES ON A SUPPORT 有权
标题翻译：用于在支持上混合样本的方法和装置
公开(公告)号：US20080113450A1
公开(公告)日：2008-05-15
申请号：US12015000
申请日：2008-01-16
申请人： Karl-Heinz Mann , Thomas Mayer , Friedhelm Vieth
发明人： Karl-Heinz Mann , Thomas Mayer , Friedhelm Vieth
IPC分类号： G01N33/566 , G01N1/00
CPC分类号： B01F13/0272 , B01F13/0059 , B01F2215/0037 , B01J2219/00493 , B01J2219/00511 , B01J2219/00605 , B01L3/508 , G01N2035/00544 , Y10T436/25
摘要： A method for detecting analytes in a liquid is provided in which the liquid is subjected to a mixing treatment on an area of a support which has in particular immobilized reactants, wherein in the mixing treatment the liquid is impinged upon by a stream of gas that sweeps across at least some areas of the support surface in a scanning manner by means of a jet directed towards the support surface. The invention also concerns a method for mixing a liquid sample comprising an analyte and a device for carrying out the method.
摘要翻译：提供了一种用于检测液体中分析物的方法，其中对特别是固定化反应物的载体的区域进行混合处理，其中在混合处理中，液体被扫过的气流冲击通过朝向支撑表面的射流以扫描方式跨过支撑表面的至少一些区域。本发明还涉及用于混合包含分析物的液体样品和用于实施该方法的装置的方法。

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