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    • 4. 发明专利
    • Agent suppressing decrease in preservative ability in amino acid-containing composition
    • 抑制含氨基酸组合物的抑制能力降低的代理
    • JP2011256137A
    • 2011-12-22
    • JP2010132388
    • 2010-06-09
    • Shiseido Co Ltd株式会社 資生堂
    • OKAWA MASAKIKOGA NOBUYOSHI
    • A61K8/44A61Q19/00
    • A61Q19/00A61K8/44A61K8/442A61K2800/10A61K2800/524
    • PROBLEM TO BE SOLVED: To provide an agent that suppresses a decrease in preservative ability in an amino acid-containing composition that has a sufficient preservative ability even if as low concentration of preservative as possible is used in combination therewith.SOLUTION: The agent that suppresses the decrease in the preservative ability is an amino acid-containing composition that contains D-amino acids. The D-amino acids may be D-glutamic acid and/or D-lysine hydrochloride. The contained amount of the agent that suppresses the decrease in the preservative ability in the amino acid-containing composition is 0.000015 to 10 mass%, and may be used in combination with 0.01 to 1.0 mass% of the preservative. The cosmetic material contains the agent that suppresses the decrease in the preservative ability in the amino acid-containing composition.
    • 待解决的问题:提供一种抑制具有足够防腐能力的含氨基酸组合物的防腐能力降低的试剂,即使与其结合使用尽可能低的防腐剂浓度也是如此。 解决方案:抑制防腐能力降低的试剂是含有D-氨基酸的含氨基酸的组合物。 D-氨基酸可以是D-谷氨酸和/或D-赖氨酸盐酸盐。 抑制含氨基酸组合物的防腐能力降低的试剂的含量为0.000015〜10质量%,可以与防腐剂的0.01〜1.0质量%组合使用。 化妆品含有抑制含氨基酸组合物的防腐能力降低的试剂。 版权所有(C)2012,JPO&INPIT
    • 6. 发明专利
    • Skin care composition for external use
    • 皮肤护理组合物外用
    • JP2008050273A
    • 2008-03-06
    • JP2006225018
    • 2006-08-22
    • Shiseido Co Ltd株式会社資生堂
    • OKAWA MASAKIOGAWA SHIGEYUKIKAMINUMA MIKIKOSUETSUGU MASARU
    • A61K8/33
    • PROBLEM TO BE SOLVED: To provide a skin care composition for external use that has satisfactory antiseptic effects without being influenced by pH or salts of a preparation system, prevents volatilization of 2-phenoxyethanol, undergoes no deterioration in antiseptic power with time, very hardly irritates skin, has no problem on stability such as separation or aggregation, and exhibits very high serviceability, stability and safety. SOLUTION: The skin care composition for external use comprises either one or two or more of diethylene glycol monoethers and triethylene glycol monoethers represented by general formula (1) (wherein R is a 5-8C alkyl or alkenyl group; and n is 2 or 3) and 2-phenoxyethanol. COPYRIGHT: (C)2008,JPO&INPIT
    • 待解决的问题:为了提供具有令人满意的防腐效果而不受制剂系统的pH或盐的影响的外用护肤组合物,防止2-苯氧基乙醇的挥发,不会随时间而消失抗菌功能, 极易刺激皮肤,在分离或聚集等稳定性方面没有问题,具有非常高的使用性,稳定性和安全性。 解决方案:外用皮肤护理组合物包含由通式(1)表示的二甘醇单醚和三甘醇单醚中的一种或两种以上(其中R为5-8C烷基或烯基; n为 2或3)和2-苯氧基乙醇。 版权所有(C)2008,JPO&INPIT
    • 7. 发明专利
    • Skin care composition
    • 皮肤护理组合物
    • JP2008050272A
    • 2008-03-06
    • JP2006225015
    • 2006-08-22
    • Shiseido Co Ltd株式会社資生堂
    • KAMINUMA MIKIKOSUETSUGU MASARUOKAWA MASAKIOGAWA SHIGEYUKI
    • A61K8/39A61Q19/00
    • PROBLEM TO BE SOLVED: To obtain a skin care composition, satisfying usability such as extremely low irritation to the skin, no greasiness, etc., having remarkably improved safety and stability. SOLUTION: The skin care composition mixed with a lower alcohol comprises one or more kinds selected from a diethylene glycol monoether and a triethylene glycol monoether represented by general formula (1) (R is either a 5-8C alkyl group or alkenyl group; n is 2 or 3) and no 1-3C lower alcohol, especially ethanol, or if mixed, the composition has ≤7 mass% of the lower alcohol mixed. COPYRIGHT: (C)2008,JPO&INPIT
    • 要解决的问题:为了获得皮肤护理组合物,满足使用性,例如对皮肤的刺激性极低,无油脂等,具有显着提高的安全性和稳定性。 < P>解决方案:与低级醇混合的皮肤护理组合物包含选自由通式(1)表示的二甘醇单醚和三甘醇单醚中的一种或多种(R是5-8C烷基或烯基 ; n为2或3),不含1-3C低级醇,特别是乙醇,或混合时,组合物的混合比例低于7%。 版权所有(C)2008,JPO&INPIT
    • 8. 发明专利
    • Method for producing powdery cosmetic
    • 生产粉末化妆品的方法
    • JP2008037844A
    • 2008-02-21
    • JP2006217951
    • 2006-08-10
    • Shiseido Co Ltd株式会社資生堂
    • HASEGAWA NOBUTSUGUSAKURAI TADASHIKAMINUMA MIKIKOSUETSUGU MASARUOKAWA MASAKI
    • A61K8/33A61Q1/12B01J2/04
    • PROBLEM TO BE SOLVED: To provide a powdery cosmetic having both excellent use feeling and sense of use, and to provide a method for producing the powdery cosmetic. SOLUTION: The method for producing the powdery cosmetic includes a slurry-preparing step for forming slurry by mixing a powder component, an oily component and a glycerol monoether represented by general formula (1): G-O-R (wherein, G is a residue obtained by removing one hydroxy group from glycerol; and R is an 8-12C alkyl or alkenyl group) in a volatile solvent, and a drying step for obtaining a dry powder by drying the resultant slurry. The dryer used in the drying step forms the slurry into fine droplets by mechanical shear force, and dries the slurry by blowing a drying gas to the fine droplets. The powdery cosmetic is obtained from the dried powder. COPYRIGHT: (C)2008,JPO&INPIT
    • 待解决的问题:提供具有优异的使用感和使用感的粉状化妆品,并提供粉状化妆品的制造方法。 解决方案:粉末化妆品的制造方法包括:通过混合由通式(1)表示的粉末成分,油性成分和甘油单醚形成浆料的浆料制备步骤:GOR(其中,G是残基 通过从甘油中除去一个羟基得到; R是8-12C烷基或链烯基);以及干燥步骤,通过干燥得到的浆料得到干燥粉末。 在干燥步骤中使用的干燥器通过机械剪切力将浆料形成细小液滴,并通过将干燥气体吹送到细小液滴来干燥浆料。 从干粉中得到粉状化妆品。 版权所有(C)2008,JPO&INPIT
    • 10. 发明专利
    • Water-in-oil type emulsified paste-like pharmaceutical preparation for lip
    • 油脂类型乳化型药物制剂
    • JP2011037723A
    • 2011-02-24
    • JP2009183906
    • 2009-08-06
    • Shiseido Co Ltd株式会社資生堂
    • ENDO YOSHIKIOKAWA MASAKI
    • A61K9/107A61K31/56A61K47/10A61K47/46
    • PROBLEM TO BE SOLVED: To provide a paste-like water-in-oil type emulsified pharmaceutical preparation for lips that is excellent in pharmaceutical stability and serviceability and free from antiseptic agents (for example, paraben-free) and gives a transparent feeling.
      SOLUTION: The water-in-oil type emulsified paste-like pharmaceutical preparation for lips comprises: (a) a dihydric alcohol (for example, propylene glycol, 1,3-butylene glycol or the like); (b) an oily component containing a solid or semi-solid oily component in a compounding ratio of at least 30 mass%; (c) 0.1-2.0 mass% of water; (d) a skin-restoring agent (for example, allantoin and derivatives thereof); (e) an anti-inflammatory agent (for example, glycyrrhetinic acid and derivatives thereof).
      COPYRIGHT: (C)2011,JPO&INPIT
    • 要解决的问题:提供药物稳定性和使用性优异且无防腐剂(例如,对羟基苯甲酸酯)的唇膏状膏状油包水型乳化药剂,并赋予透明 感觉。 油包水型乳化糊剂型口服药物制剂包括:(a)二元醇(例如丙二醇,1,3-丁二醇等); (b)含有至少30质量%的配比的固体或半固体油性成分的油性成分; (c)0.1〜2.0质量%的水; (d)皮肤恢复剂(例如尿囊素及其衍生物); (e)抗炎剂(例如甘草次酸及其衍生物)。 版权所有(C)2011,JPO&INPIT