专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

JP2012085556A Method for diagnosis of breast cancer 审中-公开
标题翻译：乳腺癌诊断方法
公开(公告)号：JP2012085556A
公开(公告)日：2012-05-10
申请号：JP2010233483
申请日：2010-10-18
申请人： Shinya Watanabe , 慎哉渡邉
发明人： WATANABE SHINYA , ITO EMI , IMAI JUNICHI , OTAKE TORU , FUJITA TEIZO , SAKAI YUKA
IPC分类号： C12Q1/68 , A61K31/7088 , A61K39/395 , A61K48/00 , A61P15/00 , A61P35/00 , C12M1/00 , C12N15/09 , G01N33/53 , G01N33/574 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a triple-negative breast cancer detection marker, a method for detection or diagnosis of triple-negative breast cancer using the marker, and a kit for detection or diagnosis of triple-negative breast cancer.SOLUTION: A melanoma inhibitory activity (MIA) gene, whose expression level is low in Luminal A, Luminal B and HER2 diseases among sub-types of breast cancer but whose expression level becomes high in the triple-negative breast cancer, and polypeptides encoded by the gene are used as triple-negative breast cancer detection markers. The triple-negative breast cancer detection markers are detected by using a detection probe for the triple-negative breast cancer marker gene and antibodies against polypeptides encoded by the gene, so that the triple-negative breast cancer can be quickly and securely detected or diagnosed.
摘要翻译：要解决的问题：提供三阴性乳腺癌检测标记，使用该标记物检测或诊断三阴性乳腺癌的方法，以及用于三阴性乳腺癌的检测或诊断的试剂盒。解决方案：一种黑素瘤抑制活性（MIA）基因，其乳腺癌亚型中的Luminal A，Luminal B和HER2疾病的表达水平低，但在三阴性乳腺癌中其表达水平变高，由该基因编码的多肽用作三阴性乳腺癌检测标记。通过使用三阴性乳腺癌标记基因的检测探针和针对由该基因编码的多肽的抗体来检测三阴性乳腺癌检测标记，从而可以快速且可靠地检测或诊断三阴性乳腺癌。版权所有（C）2012，JPO＆INPIT

2. 发明专利

JP2012085554A Method for discriminating subtype of breast cancer 审中-公开
标题翻译：用于鉴别乳腺癌亚型的方法
公开(公告)号：JP2012085554A
公开(公告)日：2012-05-10
申请号：JP2010233481
申请日：2010-10-18
申请人： Shinya Watanabe , 慎哉渡邉
发明人： WATANABE SHINYA , ITO EMI , IMAI JUNICHI , OTAKE TORU , FUJITA TEIZO , SAKAI YUKA
IPC分类号： C12N15/09 , A61K31/7088 , A61K39/395 , A61K48/00 , A61P35/00 , C12Q1/68 , G01N33/574 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a marker for detecting triple negative breast cancer; to provide a method for detecting or diagnosing the triple negative breast cancer with the marker; and to provide a kit for detecting or diagnosing the triple negative breast cancer.SOLUTION: SCRG1 gene which is low in expression level in Luminal A, Luminal B and HER2 diseases and rises the expression level in the triple negative breast cancer on the other hand among the sub-types of breast cancer, and a polypeptide encoded by the gene are used as markers for detecting the triple negative breast cancer. A probe for detecting the triple negative breast cancer marker gene and an antibody for the polypeptide encoded by the gene are used. Thus, the marker for detecting the triple negative breast cancer can be detected, and the triple negative breast cancer can quickly and surely be detected or diagnosed.
摘要翻译：要解决的问题：提供检测三阴性乳腺癌的标记物; 提供用该标记检测或诊断三阴性乳腺癌的方法; 并提供用于检测或诊断三阴性乳腺癌的试剂盒。解决方案：在Luminal A，Luminal B和HER2疾病中表达水平低的SCRG1基因和乳腺癌亚型之间的三阴性乳腺癌的表达水平升高，编码的多肽该基因被用作检测三阴性乳腺癌的标志物。使用检测三阴性乳腺癌标记基因的探针和由该基因编码的多肽的抗体。因此，可以检测出三重阴性乳腺癌的检测标记，能够快速，可靠地检测或诊断三阴性乳腺癌。版权所有（C）2012，JPO＆INPIT

3. 发明专利

JP2012085555A Marker for diagnosing breast cancer 审中-公开
标题翻译：用于诊断乳腺癌的标记
公开(公告)号：JP2012085555A
公开(公告)日：2012-05-10
申请号：JP2010233482
申请日：2010-10-18
申请人： Shinya Watanabe , 慎哉渡邉
发明人： WATANABE SHINYA , ITO EMI , IMAI JUNICHI , OTAKE TORU , FUJITA TEIZO , SAKAI YUKA
IPC分类号： C12N15/09 , C12Q1/68 , G01N33/574 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a marker for detecting triple negative breast cancer; to provide a method for detecting or diagnosing the triple negative breast cancer with the marker; and to provide a kit for detecting or diagnosing the triple negative breast cancer.SOLUTION: MMP7 gene which is low in expression level in Luminal A, Luminal B and HER2 diseases among the sub-types of breast cancer, and rises the expression level in the triple negative breast cancer on the other hand, and a polypeptide encoded by the gene are used as markers for detecting the triple negative breast cancer. A probe for detecting the triple negative breast cancer marker gene and an antibody for the polypeptide encoded by the gene are used. Thus, the marker for detecting the triple negative breast cancer can be detected, and the triple negative breast cancer can quickly and surely be detected or diagnosed.
摘要翻译：要解决的问题：提供检测三阴性乳腺癌的标记物; 提供用该标记检测或诊断三阴性乳腺癌的方法; 并提供用于检测或诊断三阴性乳腺癌的试剂盒。解决方案：在乳腺癌亚型中Luminal A，Luminal B和HER2疾病的表达水平低的MMP7基因和三阴性乳腺癌的表达水平升高，另一方面，多肽由该基因编码用作检测三阴性乳腺癌的标记物。使用检测三阴性乳腺癌标记基因的探针和由该基因编码的多肽的抗体。因此，可以检测出三重阴性乳腺癌的检测标记，能够快速，可靠地检测或诊断三阴性乳腺癌。版权所有（C）2012，JPO＆INPIT

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式