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1. 发明申请

US20080160040A1 PLANT-PRODUCED COMPOSITIONS FOR TREATING PAPILLOMAVIRUS INFECTION AND RELATED METHODS 审中-公开
标题翻译：用于治疗斑马鱼感染的植物生产组合物及相关方法
公开(公告)号：US20080160040A1
公开(公告)日：2008-07-03
申请号：US12028721
申请日：2008-02-08
申请人： Shin-je Ghim , A. Bennett Jenson , Amanda B. Lasnik , Donald M. Miller , Kenneth Palmer , Mark L. Smith
发明人： Shin-je Ghim , A. Bennett Jenson , Amanda B. Lasnik , Donald M. Miller , Kenneth Palmer , Mark L. Smith
IPC分类号： A61K39/12 , A61K35/76 , C12N15/37 , C12Q1/70 , A61P31/20
CPC分类号： A61K39/12 , A61K2039/5258 , A61K2039/55566 , A61K2039/6075 , A61K2039/70 , C07K14/005 , C07K2319/22 , C07K2319/735 , C12N7/00 , C12N15/8257 , C12N15/8258 , C12N2710/20022 , C12N2710/20034 , C12N2770/00022
摘要： Compositions for treating papillomavirus (PV) infection in a subject include a PV L2 polypeptide produced from a eukaryotic expression system.
摘要翻译：用于治疗受试者乳头瘤病毒（PV）感染的组合物包括由真核表达系统产生的PV L2多肽。

2. 发明申请

US20100221280A1 PLANT-PRODUCED COMPOSITIONS FOR TREATING PAPILLOMAVIRUS INFECTION AND RELATED METHODS 审中-公开
标题翻译：用于治疗斑马鱼感染的植物生产组合物及相关方法
公开(公告)号：US20100221280A1
公开(公告)日：2010-09-02
申请号：US12764183
申请日：2010-04-21
申请人： Shin-je Ghim , A. Bennett Jenson , Amanda B. Lasnik , Donald M. Miller , Kenneth Palmer , Mark L. Smith
发明人： Shin-je Ghim , A. Bennett Jenson , Amanda B. Lasnik , Donald M. Miller , Kenneth Palmer , Mark L. Smith
IPC分类号： A61K39/00 , C07K14/025 , A61K39/295 , A61K39/12 , A61P31/12 , C12P21/06
CPC分类号： A61K39/12 , A61K2039/5258 , A61K2039/55566 , A61K2039/6075 , A61K2039/70 , C07K14/005 , C07K2319/22 , C07K2319/735 , C12N7/00 , C12N15/8257 , C12N15/8258 , C12N2710/20022 , C12N2710/20034 , C12N2770/00022
摘要： Compositions for treating papillomavirus (PV) infection in a subject include a PV L2 polypeptide produced from a eukaryotic expression system.
摘要翻译：用于治疗受试者乳头瘤病毒（PV）感染的组合物包括由真核表达系统产生的PV L2多肽。

3. 发明申请

US20050051251A1 Tires with high strength reinforcement 失效
标题翻译：轮胎高强度加固
公开(公告)号：US20050051251A1
公开(公告)日：2005-03-10
申请号：US10970254
申请日：2004-10-21
申请人： Italo Sinopoli , Charles Hamiel , Dong Kim , Kenneth Kot , John Morgan , Kenneth Palmer , Amit Prakash , Michael Putinski , Jeffrey Smith
发明人： Italo Sinopoli , Charles Hamiel , Dong Kim , Kenneth Kot , John Morgan , Kenneth Palmer , Amit Prakash , Michael Putinski , Jeffrey Smith
IPC分类号： B29D30/38 , B60C9/00 , B60C9/02 , B60C9/08 , B60C9/18 , B60C9/20 , D07B1/06
CPC分类号： B60C9/02 , B60C9/0007 , B60C2200/14 , D07B1/0613 , D07B1/062 , D07B1/0626 , D07B1/0633 , D07B2201/2097 , D07B2205/3057 , Y10S57/902 , Y10T152/10765 , Y10T152/10855 , D07B2801/10
摘要： A strip of tire ply stock is reinforced with steel cords wherein the steel cords are constructed of high strength wire filament having at least a tensile strength of −2000 ×D+4400 MPa where D is the filament diameter in mm. Tires are constructed with the ply stock in the belt and/or carcass.
摘要翻译：一条轮胎帘布层钢丝绳用钢丝绳加固，其中钢帘线由至少拉伸强度为-2000×D + 4400MPa的高强度丝线构成，其中D是长丝直径（mm）。轮胎在皮带和/或胎体中用层压材料构造。

4. 外观设计

USD747498S1 Hunting blind 有权
公开(公告)号：USD747498S1
公开(公告)日：2016-01-12
申请号：US29477873
申请日：2013-12-27
申请人： Kenneth Palmer
设计人： Kenneth Palmer

5. 发明申请

US20060024821A1 Rolling circle replicon expression vector 审中-公开
公开(公告)号：US20060024821A1
公开(公告)日：2006-02-02
申请号：US11231725
申请日：2005-09-20
申请人： Kenneth Palmer , Gregory Pogue
发明人： Kenneth Palmer , Gregory Pogue
IPC分类号： C12N15/86
CPC分类号： C07K14/005 , A01K2217/05 , C12N15/79 , C12N15/86 , C12N2750/00022 , C12N2750/12043 , C12N2800/108 , C12N2830/42
摘要： A rolling circle DNA replicon which replicates in a host eukaryotic cell is disclosed which has a truncated replication cycle. The rolling circle DNA replicon comprises the following elements present on the same DNA molecule. It contains a Rep gene open reading frame from a virus belonging to the viral taxonomic families Geminiviridae, Circoviridae or genus Nanovirus. The Rep gene open reading frame is placed under transcriptional control of a promoter, which is placed 5′ of the gene. Any sequences that are required to be present in cis on the rolling circle DNA replicon in order that the Rep protein might promote replication of the rolling circle DNA replicon are included. An expression cassette for expression of an ancillary protein that is capable of creating a cellular environment permissive for replication of the rolling circle DNA replicon in the host cell of interest is also included. At least one expression cassette with an RNA polymerase II promoter, a multiple cloning site, and transcription termination and polyadenylation signals suitable for transcription of RNA molecules not normally intrinsic to a geminiviral, circoviral or nanoviral genome is also included.

6. 发明申请

US20060134604A1 Flexible method and apparatus for high throughput production and purification of multiple proteins 审中-公开
公开(公告)号：US20060134604A1
公开(公告)日：2006-06-22
申请号：US11303548
申请日：2005-12-16
申请人： Mark Smith , Kenneth Palmer , Gregory Pogue , John Lindbo , Kathleen Hanley , David Mannion , Gershon Wolfe
发明人： Mark Smith , Kenneth Palmer , Gregory Pogue , John Lindbo , Kathleen Hanley , David Mannion , Gershon Wolfe
IPC分类号： C12Q1/00 , G01N33/50
CPC分类号： C07K5/06165 , A61K38/00 , B01D15/1885 , B01D15/3804 , C07K5/06139
摘要： A plurality of proteins of interest, or peptides of interest, or other genetically expressed materials, are screened and subsequently produced using any of a variety of expression systems. The plurality of proteins are extracted from a plurality of separate, processed green juices, each green juice containing one of the proteins of interest. A multi-channel apparatus processes the various green juices, one green juice per channel. The apparatus is computer controlled such that the various valves in each channel and pump are controlled in an automated manner to extract each protein of interest and deliver each protein of interest into its own storage vessel.

7. 发明申请

US20050022911A1 Liquid hypergolic propellant 审中-公开
标题翻译：液体高效推进剂
公开(公告)号：US20050022911A1
公开(公告)日：2005-02-03
申请号：US10712534
申请日：2003-11-14
申请人： John Rusek , Kenneth Palmer , Donald Bower
发明人： John Rusek , Kenneth Palmer , Donald Bower
IPC分类号： C06B47/02 , C06D5/08 , C06B47/00
CPC分类号： C06D5/08 , C06B47/02
摘要： The present invention provides a liquid hypergolic propellant. In particular, a liquid hypergolic propellant is provided, containing reactive metals and/or reactive metal salts, and one or more liquid fuels, which is hypergolic when combined with an oxidizer. In addition, a sensitizer and gelling agent may be added. The reactive metals and/or reactive metal salts are defined by Formula I as follows: AxMyHz I. wherein A is one or more of any of Li, Na, and K; M is one or more of any of B, C, and Al; H is H; x is 0-3, y is 0 or greater, and z is 0 or greater, and wherein when x is 0, y is 1, and when y is 0, x is 1. The fuels are defined by the following Formula II as follows: CxHyOzNv II. wherein x is 0-8, y is 1-18, z is 0-4, and v is 0-5, and wherein when x is 0, v is 1 or greater.
摘要翻译：本发明提供了一种液体充型推进剂。特别地，提供含有反应性金属和/或反应性金属盐的一种或多种液体燃料，当与氧化剂组合时，该液体燃料是高效的。此外，可以加入敏化剂和胶凝剂。反应性金属和/或反应性金属盐由式I定义如下：AxMyHz I.其中A是Li，Na和K中的一种或多种; M是B，C和Al中的一种或多种; H为H; x为0-3，y为0或更大，z为0或更大，并且其中当x为0时，y为1，当y为0时，x为1.燃料由下式II定义为如下：CxHyOzNv II。其中x为0-8，y为1-18，z为0-4，v为0-5，而当x为0时，v为1或更大。

8. 发明申请

US20060218667A1 Plant-produced recombinant aprotinin and aprotinin variants 审中-公开
标题翻译：植物产生的重组抑肽酶和抑肽酶变体
公开(公告)号：US20060218667A1
公开(公告)日：2006-09-28
申请号：US11249685
申请日：2005-10-12
申请人： Fakhrieh Vojdani , Kenneth Palmer , Stephen Garger , Gregory Pogue
发明人： Fakhrieh Vojdani , Kenneth Palmer , Stephen Garger , Gregory Pogue
IPC分类号： A01H5/00 , C07H21/04 , C12N15/82 , C12N5/04 , A01H1/00 , C07K14/415
CPC分类号： C12N15/8257 , C07K1/34
摘要： The present invention relates to plant produced native aprotinin and aprotinin variants having enzyme-inhibitory, immunological and pharmacokinetic properties and their preparation. In a preferred method a recombinant RNA plant virus is used to express native aprotinin+variants thereof in Nicotiana plants.
摘要翻译：本发明涉及具有酶抑制，免疫学和药代动力学性质及其制备的植物产生的天然抑肽酶和抑肽酶变体。在优选的方法中，重组RNA植物病毒用于在烟草属植物中表达天然抑肽酶+变体。

9. 发明申请

US20050282263A1 Flexible vaccine assembly and vaccine delivery platform 审中-公开
标题翻译：灵活的疫苗组装和疫苗交付平台
公开(公告)号：US20050282263A1
公开(公告)日：2005-12-22
申请号：US11090497
申请日：2005-03-25
申请人： Alison McCormick , Mark Smith , Kenneth Palmer , John Lindbo , Long Nguyen , Gregory Pogue
发明人： Alison McCormick , Mark Smith , Kenneth Palmer , John Lindbo , Long Nguyen , Gregory Pogue
IPC分类号： C12N7/00 , C12N7/04 , C12N15/86
CPC分类号： C12N7/00 , A61K2039/5258 , C12N2710/20022 , C12N2770/00023
摘要： Herein described are various methods for making a vaccine that are made of re-assembled virus like particles (VLP). First, the VLPs are disassembled into coat proteins or encapsidation intermediate populations. Each population undergoes, for instance, chemical conjugation of unique peptide or nucleic moieties to form separate populations. Thereafter, a predetermined amount of each of the several (one or more) different coat proteins or encapsidation intermediates from the different populations is mixed and joined, forming intact VLPs, surrounding a nucleic acid core, that are composed of different coat proteins such that the reassembled VLP displays more than one peptide or other molecule. The nucleic acid can function either as a scaffold alone or can be engineered for the expression of an immunomodulatory protein in a eukaryotic cell.
摘要翻译：本文描述了制备由重新组装的病毒样颗粒（VLP）制成的疫苗的各种方法。首先，将VLP分解成外壳蛋白或衣壳化中间种群。每个群体经历例如独特的肽或核酸部分的化学共轭以形成分开的群体。此后，将来自不同群体的几种（一种或多种）不同外壳蛋白或壳化中间体中的每一种的预定量混合并连接，形成围绕核酸核心的完整VLP，其由不同的外壳蛋白组成，使得重组VLP显示多于一个肽或其他分子。核酸可以作为单独的支架起作用，或者可以被工程化以在真核细胞中表达免疫调节蛋白。

10. 发明授权

US06559118B1 Fragrance compounds 失效
标题翻译：香料化合物
公开(公告)号：US06559118B1
公开(公告)日：2003-05-06
申请号：US09980855
申请日：2001-12-07
申请人： Kenneth Palmer
发明人： Kenneth Palmer
IPC分类号： A61K746
CPC分类号： C11B9/0034 , C07C31/276 , C07C33/14
摘要： Novel compounds having the structure (I) where R1 is a lower alkyl group, R2, R3, R4 and R5 is each independently hydrogen or a lower alkyl group, R6 is hydrogen, a lower alkyl group, an alkylidene group or a lower alkenyl group and R7 is hydrogen or a lower alkyl group, have desirable odor properties, possibly of a blackcurrant, green, buchu, cassis nature, and find use in perfumes and perfumed products.
摘要翻译：具有结构（I）的新型化合物，其中R 1为低级烷基，R 2，R 3，R 4和R 5各自独立地为氢或低级烷基，R 6为氢，低级烷基，亚烷基或低级烯基并且R7是氢或低级烷基，具有可能具有黑醋栗，绿色，布丘，黑醋栗性质的所需气味特性，并用于香料和香料产品中。

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