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1. 发明授权

US4689568A NMR chemical shift imaging method 失效
标题翻译： NMR化学位移成像方法
公开(公告)号：US4689568A
公开(公告)日：1987-08-25
申请号：US750475
申请日：1985-07-01
申请人： Shigeru Matsui , Kensuke Sekihara , Hideki Kohno , Takashi Onodera , Hidemi Shiono
发明人： Shigeru Matsui , Kensuke Sekihara , Hideki Kohno , Takashi Onodera , Hidemi Shiono
IPC分类号： G01R33/44 , A61B5/055 , A61B10/00 , G01R33/48 , G01R33/485 , G01R33/561 , G01R33/20
CPC分类号： G01R33/485 , G01R33/5616
摘要： An NMR imaging method which provides a three-dimensional image representative of the two-dimensional distribution of nuclear spin species resolved by chemical shift or the local spectra resolved by two-dimensional location. After the excitation of nuclear spins and the phase-encoding by application of a field gradient G.sub.y, a periodically inverting field gradient G.sub.x is generated to yield a continuous echo train. The echo train is sampled and separated into data of odd-numbered echoes and data of even-numbered echoes which data are in turn reconstructed into two-dimensional data arrays, respectively. The data thus reconstructed are three-dimensional Fourier-transformed.
摘要翻译：提供表示通过化学位移分解的核自旋物质的二维分布的三维图像的NMR成像方法或通过二维位置解析的局部光谱。在核自旋的激励和通过施加场梯度Gy的相位编码之后，产生周期性反转场梯度Gx以产生连续的回波串。回波串被采样并分离成奇数回波的数据和偶数回波的数据，数据又分别被重建成二维数据阵列。这样重建的数据是三维傅里叶变换的。

2. 发明授权

US4797616A High speed NMR spectroscopic imaging method 失效
标题翻译：高速NMR光谱成像方法
公开(公告)号：US4797616A
公开(公告)日：1989-01-10
申请号：US151901
申请日：1988-02-03
申请人： Shigeru Matsui , Takashi Onodera , Kensuke Sekihara , Hidemi Shiono , Hideki Kohno
发明人： Shigeru Matsui , Takashi Onodera , Kensuke Sekihara , Hidemi Shiono , Hideki Kohno
IPC分类号： G01R33/32 , A61B5/055 , A61B10/00 , G01R33/44 , G01R33/48 , G01R33/485 , G01R33/20
CPC分类号： G01R33/485
摘要： An NMR spectroscopic imaging method of obtaining separate spin distribution images for respective spectral components of the spectrum of an NMR signal caused by the chemical shift of nuclides of interest in an object includes providing for a transversal magnetization signal of the object placed in a static magnetic field. A position of the signal in a phase domain is translated in a K-space from the origin thereof. Further, the signal is sampled while rotating a position of the signal in the K-space plural times on a certain circle in the K-space by applying a rotating field gradient, thereby to obtain a group of signal data. Signal data trains each of which is composed of signal data present at the same position on the K-space in the signal data group obtained by the sampling during the plural signal rotations, is subjected to Fourier transformations, respectively, thereby effecting a spectral analysis of the NMR signal.
摘要翻译：由对象物质的化学位移引起的核磁共振信号频谱的各频谱分量的分离自旋分布图像的NMR分光成像方法包括提供放置在静磁场中的物体的横向磁化信号。信号在相位域中的位置从其原点在K空间中平移。此外，在通过施加旋转场梯度在K空间中的某个圆上多次旋转K空间中的信号的位置的同时对信号进行采样，从而获得一组信号数据。由多个信号旋转中的采样获得的信号数据组中的与K空间上的相同位置处的信号数据组成的信号数据串分别进行傅里叶变换，从而进行频谱分析 NMR信号。

3. 发明授权

US4716369A High speed imaging method with three-dimensional NMR 失效
标题翻译：高速成像方法采用三维NMR
公开(公告)号：US4716369A
公开(公告)日：1987-12-29
申请号：US746663
申请日：1985-06-20
申请人： Kensuke Sekihara , Shigeru Matsui , Hideki Kohno , Etsuji Yamamoto , Hidemi Shiono
发明人： Kensuke Sekihara , Shigeru Matsui , Hideki Kohno , Etsuji Yamamoto , Hidemi Shiono
IPC分类号： G01R33/485 , G01R33/561 , G01R33/20
CPC分类号： G01R33/485 , G01R33/5615 , G01R33/5616
摘要： The present invention is an imaging method using three-dimensional NMR to which an echo-planar method is applied. After excitation of nuclear spins, the gradient magnetic field Gx for phase-encoding is applied and there is repeated a sequence of measuring and obtaining an echo train of spin-echoes with a constant gradient magnetic field Gx and a periodically-inverted gradient magnetic field Gy, as varying the amount of encoding, so as to obtain the three-dimensional imaging by the Fourier-conversion. Moreover, after the selective excitation of spins within an X-Y surface, a 180.degree. radio frequency pulse is applied. As varying the time difference .tau..sub..epsilon. between the interval from the excitation until the application of the 180.degree. radio frequency pulse and the interval from the application thereof until a peak of a first echo of an echo train, three-dimensional imaging is carried out with a chemical shift axis as one axis by repeating the sequence and accomplishing Fourier-conversion with .tau..sub..epsilon. as a numerical variable.
摘要翻译：本发明是使用采用回波平面法的三维NMR的成像方法。在激励核自旋之后，施加用于相位编码的梯度磁场Gx，并且重复测量并获得具有恒定梯度磁场Gx和周期性反转梯度磁场Gy的自旋回波回波序列的序列，因为改变编码量，从而通过傅里叶变换获得三维成像。此外，在X-Y表面中的自旋选择性激发之后，施加180°射频脉冲。随着从激励到施加180°射频脉冲的间隔与从应用到应用的间隔直到回波列的第一回波的峰值之间的时间差τεε改变，三维成像是化学位移轴作为一个轴，通过重复该序列，并以tauε作为数值变量进行傅里叶变换。

4. 发明授权

US4211926A Tomographic imaging system 失效
标题翻译：断层成像系统
公开(公告)号：US4211926A
公开(公告)日：1980-07-08
申请号：US901241
申请日：1978-04-28
申请人： Chitose Nakaya , Hideki Kohno , Hidemi Shiono , Kensuke Sekihara , Shinji Yamamoto , Teruichi Tomura , Takayuki Hayakawa
发明人： Chitose Nakaya , Hideki Kohno , Hidemi Shiono , Kensuke Sekihara , Shinji Yamamoto , Teruichi Tomura , Takayuki Hayakawa
IPC分类号： G01N23/04 , A61B6/03 , A61B8/00 , G06Q50/22 , G06Q50/24 , G06T11/00 , G03B41/16
CPC分类号： A61B6/032
摘要： In a system in which the tomographic image of an object under investigation is produced on the basis of the amount of absorption of radiation by the object when a source of radiation and a plurality of radiation sensitive detectors with the object interposed therebetween are rotated around the object, the output signal from at least one of the plural detectors is used to correct the radiation absorption amount. Another selected one of the plural detectors may be used for checking whether the object is positioned within a useful detection view.
摘要翻译：在这样一个系统中，在被照明物体插入其间的物体的多个辐射敏感探测器围绕物体旋转时，基于物体的辐射吸收量产生被研究对象的断层图像使用来自多个检测器中的至少一个的输出信号来校正辐射吸收量。多个检测器中的另一选择的一个可以用于检查对象是否位于有用的检测视图内。

5. 发明授权

US4739265A NMR imaging method 失效
标题翻译： NMR成像方法
公开(公告)号：US4739265A
公开(公告)日：1988-04-19
申请号：US846151
申请日：1986-03-31
申请人： Etsuji Yamamoto , Kensuke Sekihara , Hidemi Shiono , Hideki Kohno
发明人： Etsuji Yamamoto , Kensuke Sekihara , Hidemi Shiono , Hideki Kohno
IPC分类号： G01R33/485 , G01R33/565 , G01R33/20
CPC分类号： G01R33/565 , G01R33/485 , G01R33/56527
摘要： A method for providing spin density distribution images of an object, discriminated with respect to plural chemical shifts. This method is performed by repeating a measurement sequence in a spin warp imaging method, of the spin data plural times, with a time difference .DELTA..tau. between a time interval .tau..sub.1 from spin excitation to a 180.degree. RF pulse and a time interval .tau..sub.2 from the 180.degree. RF pulse to a peak of a spin echo, altering .DELTA..tau. in the ways corresponding the number of chemical shifts to be discriminated from one another, subjecting the respective spin data to two-dimensional Fourier transform to provide plural sets of spin data for respective coordinates in a spatial domain, and solving simultaneous equations of the sets of spin data to provide spin densities corresponding to the respective chemical shifts.
摘要翻译：一种用于提供对象的自旋密度分布图像的方法，其被鉴别为多个化学位移。该方法通过在旋转数据成像方法中重复自旋数据多次的测量序列，其中从自旋激发到180°RF脉冲的时间间隔τ1与时间间隔τ2之间的时间差DELTAτ 从180°RF脉冲到自旋回波的峰值，以相应于要彼此区分的化学位移数的方式改变DELTA tau，对各自旋转数据进行二维傅里叶变换以提供多组旋转用于空间域中的各个坐标的数据，以及求解自旋数据组的联立方程以提供对应于各个化学位移的自旋密度。

6. 发明授权

US4212062A Tomographic imaging system 失效
标题翻译：断层成像系统
公开(公告)号：US4212062A
公开(公告)日：1980-07-08
申请号：US919627
申请日：1978-06-27
申请人： Hideki Kohno , Hidemi Shiono , Chitose Nakaya , Kensuke Sekihara , Teruichi Tomura , Shinji Yamamoto , Takayuki Hayakawa , Isao Horiba , Shigenobu Yanaka
发明人： Hideki Kohno , Hidemi Shiono , Chitose Nakaya , Kensuke Sekihara , Teruichi Tomura , Shinji Yamamoto , Takayuki Hayakawa , Isao Horiba , Shigenobu Yanaka
IPC分类号： G01N23/04 , A61B6/03 , G06Q50/22 , G06Q50/24 , G06T11/00 , G06F15/34
CPC分类号： A61B6/032 , G06T11/006 , Y10S378/901
摘要： A tomographic imaging system is disclosed in which the quantity of absorption or transmittance of a transmissive radiation by or through a certain tomographic cross-section of an object under consideration is detected and the distribution of radiation absorption or transmittance in the cross-section is reconstructed through a convolution operation. A weighting function used in the convolution operation is prepared with a predetermined one of its positive orders the value of which is an integration of the weighting function from the predetermined positive order to positive infinity and a predetermined one of its negative orders the value of which is in integration of the weighting function from the predetermined negative order to negative infinity.
摘要翻译：公开了一种断层图像成像系统，其中检测由所考虑的物体的特定断层摄影横截面或通过所考虑的物体的某些断层摄影横截面的透射辐射的吸收或透射率，并且通过以下方式重建横截面中的辐射吸收或透射率的分布：卷积运算在卷积运算中使用的加权函数以其正值中的预定的一个准备，该值的正值为加权函数从预定的正阶数到正无穷大的积分，以及负值的预定值，其值是将加权函数从预定的负数整合到负无穷大。

7. 发明授权

US4485480A Radiation image photographing apparatus 失效
标题翻译：辐射摄影装置
公开(公告)号：US4485480A
公开(公告)日：1984-11-27
申请号：US366781
申请日：1982-04-08
申请人： Hideki Kohno , Hidemi Shiono , Kensuke Sekihara , Shigenobu Yanaka , Takaji Suzuki
发明人： Hideki Kohno , Hidemi Shiono , Kensuke Sekihara , Shigenobu Yanaka , Takaji Suzuki
IPC分类号： G01N23/04 , A61B6/00 , A61B6/02 , H05G1/60 , G03B41/16
CPC分类号： A61B6/4476 , H05G1/60
摘要： A radiation-image photographing apparatus comprises a radiation source, a radiation detector disposed in opposition to the radiation source for detecting radiation through an object to be examined and to generate an electrical signal proportional to the amount of incident radiation, a scanning device for changing the relative, positional relationship between the radiation source and the radiation detector, an analog-to-digital converter for converting the output signal from the radiation detector to a digital quantity, a memory for storing the digital signal, an arithmetic unit, and a display unit. A plurality of measurements of a two-dimensional radiation absorption distribution of the object disposed between the radiation source and the radiation detector is obtained while the relative positional relationship between the radiation source and the radiation detector is being changed, and a linear arithmetic operation is performed on the plurality of image measurements, or a set of data passing a point within the object to be photographed, thereby displaying a cross-sectional image on a given cross-section approximately parallel to the radiation detector plane within the object to be examined.
摘要翻译：辐射图像拍摄装置包括辐射源，与辐射源相对设置的放射线检测器，用于检测通过待检查物体的辐射并产生与入射辐射量成比例的电信号;扫描装置，用于改变辐射源和辐射检测器之间的相对位置关系，用于将来自辐射检测器的输出信号转换为数字量的模拟 - 数字转换器，用于存储数字信号的存储器，运算单元和显示单元。在辐射源和辐射检测器之间的相对位置关系正在改变的同时，获得放置在辐射源和放射线检测器之间的物体的二维辐射吸收分布的多个测量值，并进行线性算术运算或多个图像测量中的一组数据，或者通过要拍摄的对象内的点的一组数据，从而在与被检查对象内的放射线检测器平面近似平行的给定横截面上显示横截面图像。

8. 发明授权

US5109197A Nuclear magnetic resonance multi-echo imaging method and apparatus 失效
标题翻译：核磁共振多重成像方法和装置
公开(公告)号：US5109197A
公开(公告)日：1992-04-28
申请号：US578766
申请日：1990-09-07
申请人： Takashi Onodera , Hidemi Shiono , Hideki Kohno
发明人： Takashi Onodera , Hidemi Shiono , Hideki Kohno
IPC分类号： A61B5/055 , G01R33/48 , G01R33/565
CPC分类号： G01R33/56554
摘要： A nuclear magnetic resonance multi-echo imaging method and an apparatus therefor in which gradient field pulses having predetermined products of intensity and time are applied on both sides of an inversion pulse in at least two of three directions which are orthogonal to each other to dephase components of a magnetization vector which leads to an artifact signal and an error signal, whereby only a normal echo signal can be sampled to form a correct image.

9. 发明授权

US4683433A Imaging method and apparatus using nuclear magnetic resonance 失效
标题翻译：使用核磁共振的成像方法和装置
公开(公告)号：US4683433A
公开(公告)日：1987-07-28
申请号：US636995
申请日：1984-08-02
申请人： Etsuji Yamamoto , Hideki Kohno , Masao Kuroda , Shigeru Matsui , Hidemi Shiono
发明人： Etsuji Yamamoto , Hideki Kohno , Masao Kuroda , Shigeru Matsui , Hidemi Shiono
IPC分类号： G01R33/20 , A61B5/055 , A61B10/00 , G01R33/48 , G01R33/54 , G01R33/56
CPC分类号： G01R33/482 , G01R33/56
摘要： An NMR imaging apparatus and method for detecting a nuclear spin resonance signal from an object, which is placed in a magnetic field, to produce images of the object. At an instant when the spins come into phase after the signal detection by a first spin excitation, RF magnetic field pulses are applied for rotating the direction of the spin to that opposite to the initial state. After that, the spin excitation and the signal direction of second time are conducted to measure the data which are different in the effect of the relaxation time from the first measurements. By repeating these sequences, it is possible to produce a plurality of images such as an intensity image or a relaxation time enhanced image.
摘要翻译：一种用于检测放置在磁场中的物体的核自旋共振信号的NMR成像设备和方法，以产生物体的图像。在通过第一自旋激发在信号检测之后自旋进入相位的瞬间，施加RF磁场脉冲以将旋转方向旋转到与初始状态相反的方向。之后，进行自旋激励和第二次的信号方向，以测量与第一次测量相比，松弛时间的影响不同的数据。通过重复这些序列，可以产生多个图像，例如强度图像或弛豫时间增强图像。

10. 发明授权

US4760339A NMR imaging method 失效
标题翻译： NMR成像方法
公开(公告)号：US4760339A
公开(公告)日：1988-07-26
申请号：US944001
申请日：1986-12-22
申请人： Etsuji Yamamoto , Koichi Sano , Hidemi Shiono , Hideki Kohno
发明人： Etsuji Yamamoto , Koichi Sano , Hidemi Shiono , Hideki Kohno
IPC分类号： A61B10/00 , A61B5/055 , G01R33/48 , G01R33/485 , G01R33/565 , G01R33/20
CPC分类号： G01R33/565 , G01R33/485 , G01R33/56527
摘要： An NMR imaging method is disclosed in which an object is measured in accordance with a pulse sequence capable of expressing a difference between two of a plurality of chemical shifts by a phase difference in a signal, that is, a pulse sequence 90.degree.-.tau..sub.a -180.degree.-.tau..sub.b -spin echo (where .tau..sub.a .noteq..tau..sub.b) to obtain spin distribution data, a histogram with respect to the phase of the spin distribution data is formed to regard a phase corresponding to that one of a plurality of peaks of the histogram which exists at one end of the histogram, as a position-independent offset phase which is contained in the spin distribution data and is peculiar to an NMR imaging apparatus, and the spin distribution data is corrected using the offset value thus obtained, to extract spin density distribution data for each of the chemical shifts from the corrected spin distribution data.
摘要翻译：公开了一种NMR成像方法，其中根据能够通过信号的相位差表示多个化学位移之间的差异的脉冲序列来测量物体，即脉冲序列90°-τa -180°-τb-自旋回波（其中τa NOTEQUAL tau b）为了获得自旋分布数据，形成相对于自旋分布数据的相位的直方图，以考虑与多个峰中的那一个相对应的相位存在于直方图的一端的直方图作为自旋分布数据中包含的并且是NMR成像设备特有的与位置无关的偏移相位，并且使用由此获得的偏移值来校正自旋分布数据，从校正的自旋分布数据中提取每个化学位移的自旋密度分布数据。

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